RNA-seq Results

Results indicating the target gene (SPTBN2 ) expression regulated by m6A regulator (METTL3 )
2B33: Malignant haematopoietic neoplasm
In total 1 results
Result 1 indicating the SPTBN2 expression regulated by METTL3
Cell Line Raw 264.7 cell line CVCL_0493
Condition Leukemia Mus musculus
Treatment: METTL3 knockout Raw 264.7 cells
Control: Wild type Raw 264.7 cells
 GSE162248
Regulation
logFC: -7.43E-01
 p-value: 1.66E-02
2B91: Colorectal cancer
In total 2 results
Result 1 indicating the SPTBN2 expression regulated by METTL3
Cell Line Caco-2 cell line CVCL_0025
Condition Colorectal adenocarcinoma Homo sapiens
Treatment: shMETTL3 Caco-2 cells
Control: shNTC Caco-2 cells
 GSE167075
Regulation
logFC: -1.19E+00
 p-value: 2.92E-45
Result 2 indicating the SPTBN2 expression regulated by METTL3
Cell Line DKO-1 cell line CVCL_9798
Condition Colorectal cancer Homo sapiens
Treatment: METTL3 knockdown DKO-1 cell
Control: DKO-1 cell
 GSE182382
Regulation
logFC: -9.02E-01
 p-value: 4.70E-05
2C60: Breast cancer
In total 1 results
Result 1 indicating the SPTBN2 expression regulated by METTL3
Cell Line MDA-MB-231 CVCL_0062
Condition Breast cancer Homo sapiens
Treatment: METTL3 knockdown MDA-MB-231 cells
Control: MDA-MB-231 cells
 GSE70061
Regulation
logFC: -8.07E-01
 p-value: 4.45E-02
Healthy
In total 7 results
Result 1 indicating the SPTBN2 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
 GSE198513
Regulation
logFC: -1.22E+00
 p-value: 4.44E-23
Result 2 indicating the SPTBN2 expression regulated by METTL3
Cell Line Mouse testis
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mouse testis
Control: Mouse testis
 GSE99771
Regulation
logFC: -1.02E+00
 p-value: 1.38E-02
Result 3 indicating the SPTBN2 expression regulated by METTL3
Cell Line ARPE-19 cell line CVCL_0145
Condition Healthy Homo sapiens
Treatment: shMETTL3 ARPE-19 cells
Control: shControl ARPE-19 cells
 GSE202017
Regulation
logFC: -1.43E+00
 p-value: 7.91E-07
Result 4 indicating the SPTBN2 expression regulated by METTL3
Cell Line mouse embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- ESCs
Control: Wild type ESCs
 GSE145309
Regulation
logFC: 2.55E+00
 p-value: 9.59E-54
Result 5 indicating the SPTBN2 expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout mESCs
Control: Wild type mESCs
 GSE156481
Regulation
logFC: 1.86E+00
 p-value: 3.12E-20
Result 6 indicating the SPTBN2 expression regulated by METTL3
Cell Line E14.5 LSK cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout E14.5 LSK cells
Control: Wild type E14.5 LSK cells
 GSE148882
Regulation
logFC: -2.51E+00
 p-value: 3.35E-03
Result 7 indicating the SPTBN2 expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- mESCs
Control: Wild type ESCs
 GSE147849
Regulation
logFC: 1.45E+00
 p-value: 5.17E-03