Results indicating the target gene (RIG-I ) expression regulated by m6A regulator (METTL3 )
2B33: Malignant haematopoietic neoplasm
In total 1 results
Result 1 indicating the RIG-I expression regulated by METTL3
Cell Line Raw 264.7 cell line CVCL_0493
Condition Leukemia Mus musculus
Treatment: METTL3 knockout Raw 264.7 cells
Control: Wild type Raw 264.7 cells
GSE162248
Regulation
logFC: -8.64E-01
p-value: 2.38E-34
Healthy
In total 8 results
Result 1 indicating the RIG-I expression regulated by METTL3
Cell Line Pancreatic islets
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mice
Control: Mettl3 flox/flox mice
GSE155612
Regulation
logFC: 1.07E+00
p-value: 3.95E-03
Result 2 indicating the RIG-I expression regulated by METTL3
Cell Line LX2 cell line CVCL_5792
Condition Healthy Homo sapiens
Treatment: shMETTL3 LX2 cells
Control: shLuc LX2 cells
GSE207909
Regulation
logFC: -1.14E+00
p-value: 3.48E-03
Result 3 indicating the RIG-I expression regulated by METTL3
Cell Line mouse embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- ESCs
Control: Wild type ESCs
GSE145309
Regulation
logFC: 6.06E-01
p-value: 1.18E-25
Result 4 indicating the RIG-I expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout mESCs
Control: Wild type mESCs
GSE156481
Regulation
logFC: -1.72E+00
p-value: 9.43E-23
Result 5 indicating the RIG-I expression regulated by METTL3
Cell Line E14.5 LSK cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout E14.5 LSK cells
Control: Wild type E14.5 LSK cells
GSE148882
Regulation
logFC: 9.20E-01
p-value: 6.04E-15
Result 6 indicating the RIG-I expression regulated by METTL3
Cell Line Th1 cell line CVCL_5J51
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Th1 cells
Control: Wild type splenic Th1 cells
GSE129648
Regulation
logFC: 1.30E+00
p-value: 2.10E-13
Result 7 indicating the RIG-I expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout ES cells
Control: Wild type ES cells
GSE157262
Regulation
logFC: 1.11E+00
p-value: 4.01E-04
Result 8 indicating the RIG-I expression regulated by METTL3
Cell Line Bone-marrow-derived macrophages
Condition Healthy Mus musculus
Treatment: Mettl3fl/fl (KO) BMDMs
Control: Wild type BMDMs
GSE182865
Regulation
logFC: 6.98E-01
p-value: 5.78E-03