Results indicating the target gene (SIRT1 ) expression regulated by m6A regulator (METTL3 )
Healthy
In total 4 results
Result 1 indicating the SIRT1 expression regulated by METTL3
Cell Line Mouse testis
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mouse testis
Control: Mouse testis
GSE99771
Regulation
logFC: -3.40E+00
p-value: 1.89E-04
Result 2 indicating the SIRT1 expression regulated by METTL3
Cell Line Pancreatic islets
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mice
Control: Mettl3 flox/flox mice
GSE155612
Regulation
logFC: 9.68E-01
p-value: 1.92E-04
Result 3 indicating the SIRT1 expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout mESCs
Control: Wild type mESCs
GSE156481
Regulation
logFC: -7.40E-01
p-value: 1.00E-18
Result 4 indicating the SIRT1 expression regulated by METTL3
Cell Line Th1 cell line CVCL_5J51
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Th1 cells
Control: Wild type splenic Th1 cells
GSE129648
Regulation
logFC: -1.41E+00
p-value: 1.52E-02