Results indicating the target gene (PTEN ) expression regulated by m6A regulator (METTL3 )
2B90: Colon cancer
In total 1 results
Result 1 indicating the PTEN expression regulated by METTL3
Cell Line CT26 cell line CVCL_7254
Condition Colon adenocarcinoma Mus musculus
Treatment: METTL3 knockout CT26 cells
Control: CT26 cells
GSE142589
Regulation
logFC: -7.82E-01
p-value: 1.11E-02
2B91: Colorectal cancer
In total 1 results
Result 1 indicating the PTEN expression regulated by METTL3
Cell Line Caco-2 cell line CVCL_0025
Condition Colorectal adenocarcinoma Homo sapiens
Treatment: shMETTL3 Caco-2 cells
Control: shNTC Caco-2 cells
GSE167075
Regulation
logFC: 7.07E-01
p-value: 7.38E-25
Healthy
In total 4 results
Result 1 indicating the PTEN expression regulated by METTL3
Cell Line Pancreatic islets
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mice
Control: Mettl3 flox/flox mice
GSE155612
Regulation
logFC: 9.93E-01
p-value: 1.29E-04
Result 2 indicating the PTEN expression regulated by METTL3
Cell Line LX2 cell line CVCL_5792
Condition Healthy Homo sapiens
Treatment: shMETTL3 LX2 cells
Control: shLuc LX2 cells
GSE207909
Regulation
logFC: 9.60E-01
p-value: 1.46E-37
Result 3 indicating the PTEN expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout mESCs
Control: Wild type mESCs
GSE156481
Regulation
logFC: 7.35E-01
p-value: 3.63E-27
Result 4 indicating the PTEN expression regulated by METTL3
Cell Line Tfh cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Tfh cells
Control: Wild type splenic Tfh cells
GSE129648
Regulation
logFC: -8.93E-01
p-value: 1.18E-02