Results indicating the target gene (PLK1 ) expression regulated by m6A regulator (METTL3 )
2B33: Malignant haematopoietic neoplasm
In total 1 results
Result 1 indicating the PLK1 expression regulated by METTL3
Cell Line Raw 264.7 cell line CVCL_0493
Condition Leukemia Mus musculus
Treatment: METTL3 knockdown RAW264.7cells
Control: RAW 264.7cells
GSE192603
Regulation
logFC: 2.52E+00
p-value: 3.83E-02
Healthy
In total 7 results
Result 1 indicating the PLK1 expression regulated by METTL3
Cell Line Cerebral cortex
Condition Healthy Mus musculus
Treatment: FTO (f/f, Emx1-cre) cerebral cortex
Control: Wild type cerebral cortex
GSE154992
Regulation
logFC: 6.30E-01
p-value: 6.20E-06
Result 2 indicating the PLK1 expression regulated by METTL3
Cell Line Pancreatic islets
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mice
Control: Mettl3 flox/flox mice
GSE155612
Regulation
logFC: 1.45E+00
p-value: 5.61E-04
Result 3 indicating the PLK1 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3-deficient liver
Control: Wild type liver cells
GSE197800
Regulation
logFC: 3.67E+00
p-value: 6.71E-03
Result 4 indicating the PLK1 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
GSE198512
Regulation
logFC: 1.62E+00
p-value: 4.86E-02
Result 5 indicating the PLK1 expression regulated by METTL3
Cell Line LX2 cell line CVCL_5792
Condition Healthy Homo sapiens
Treatment: shMETTL3 LX2 cells
Control: shLuc LX2 cells
GSE207909
Regulation
logFC: -8.98E-01
p-value: 1.15E-18
Result 6 indicating the PLK1 expression regulated by METTL3
Cell Line ARPE-19 cell line CVCL_0145
Condition Healthy Homo sapiens
Treatment: shMETTL3 ARPE-19 cells
Control: shControl ARPE-19 cells
GSE202017
Regulation
logFC: 6.07E-01
p-value: 1.45E-02
Result 7 indicating the PLK1 expression regulated by METTL3
Cell Line Mesenchymal stem cell line
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mesenchymal stem cells
Control: Wild type mesenchymal stem cells
GSE114933
Regulation
logFC: -7.46E-01
p-value: 1.53E-04