Results indicating the target gene (NOTCH1 ) expression regulated by m6A regulator (METTL3 )
2B91: Colorectal cancer
In total 2 results
Result 1 indicating the NOTCH1 expression regulated by METTL3
Cell Line Caco-2 cell line CVCL_0025
Condition Colorectal adenocarcinoma Homo sapiens
Treatment: shMETTL3 Caco-2 cells
Control: shNTC Caco-2 cells
GSE167075
Regulation
logFC: -6.26E-01
p-value: 1.11E-02
Result 2 indicating the NOTCH1 expression regulated by METTL3
Cell Line DKO-1 cell line CVCL_9798
Condition Colorectal cancer Homo sapiens
Treatment: METTL3 knockdown DKO-1 cell
Control: DKO-1 cell
GSE182382
Regulation
logFC: -1.53E+00
p-value: 1.92E-06
2C60: Breast cancer
In total 1 results
Result 1 indicating the NOTCH1 expression regulated by METTL3
Cell Line MDA-MB-231 CVCL_0062
Condition Breast cancer Homo sapiens
Treatment: METTL3 knockdown MDA-MB-231 cells
Control: MDA-MB-231 cells
GSE70061
Regulation
logFC: -6.73E-01
p-value: 3.61E-03
Healthy
In total 6 results
Result 1 indicating the NOTCH1 expression regulated by METTL3
Cell Line Cerebral cortex
Condition Healthy Mus musculus
Treatment: FTO (f/f, Emx1-cre) cerebral cortex
Control: Wild type cerebral cortex
GSE154992
Regulation
logFC: 8.49E-01
p-value: 7.80E-18
Result 2 indicating the NOTCH1 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
GSE198512
Regulation
logFC: 1.16E+00
p-value: 4.35E-03
Result 3 indicating the NOTCH1 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3-deficient liver
Control: Wild type liver cells
GSE197800
Regulation
logFC: 6.35E-01
p-value: 2.93E-02
Result 4 indicating the NOTCH1 expression regulated by METTL3
Cell Line LX2 cell line CVCL_5792
Condition Healthy Homo sapiens
Treatment: shMETTL3 LX2 cells
Control: shLuc LX2 cells
GSE207909
Regulation
logFC: -6.68E-01
p-value: 1.32E-12
Result 5 indicating the NOTCH1 expression regulated by METTL3
Cell Line mouse embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- ESCs
Control: Wild type ESCs
GSE145309
Regulation
logFC: 1.79E+00
p-value: 4.31E-269
Result 6 indicating the NOTCH1 expression regulated by METTL3
Cell Line E14.5 LSK cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout E14.5 LSK cells
Control: Wild type E14.5 LSK cells
GSE148882
Regulation
logFC: -6.62E-01
p-value: 1.83E-23