Results indicating the target gene (AK4 ) expression regulated by m6A regulator (METTL3 )
2B33: Malignant haematopoietic neoplasm
In total 1 results
Result 1 indicating the AK4 expression regulated by METTL3
Cell Line Raw 264.7 cell line CVCL_0493
Condition Leukemia Mus musculus
Treatment: METTL3 knockdown RAW264.7cells
Control: RAW 264.7cells
GSE192603
Regulation
logFC: -1.22E+00
p-value: 3.20E-02
2B91: Colorectal cancer
In total 2 results
Result 1 indicating the AK4 expression regulated by METTL3
Cell Line Caco-2 cell line CVCL_0025
Condition Colorectal adenocarcinoma Homo sapiens
Treatment: shMETTL3 Caco-2 cells
Control: shNTC Caco-2 cells
GSE167075
Regulation
logFC: -5.87E-01
p-value: 2.40E-51
Result 2 indicating the AK4 expression regulated by METTL3
Cell Line DKO-1 cell line CVCL_9798
Condition Colorectal cancer Homo sapiens
Treatment: METTL3 knockdown DKO-1 cell
Control: DKO-1 cell
GSE182382
Regulation
logFC: -8.51E-01
p-value: 2.19E-02
2C60: Breast cancer
In total 1 results
Result 1 indicating the AK4 expression regulated by METTL3
Cell Line MDA-MB-231 CVCL_0062
Condition Breast cancer Homo sapiens
Treatment: METTL3 knockdown MDA-MB-231 cells
Control: MDA-MB-231 cells
GSE70061
Regulation
logFC: -8.28E-01
p-value: 1.32E-02
Healthy
In total 9 results
Result 1 indicating the AK4 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3-deficient liver
Control: Wild type liver cells
GSE197800
Regulation
logFC: -1.46E+00
p-value: 2.70E-09
Result 2 indicating the AK4 expression regulated by METTL3
Cell Line Cerebral cortex
Condition Healthy Mus musculus
Treatment: FTO (f/f, Emx1-cre) cerebral cortex
Control: Wild type cerebral cortex
GSE154992
Regulation
logFC: 6.13E-01
p-value: 1.37E-06
Result 3 indicating the AK4 expression regulated by METTL3
Cell Line Soma
Condition Healthy Mus musculus
Treatment: Mettl3-/- soma
Control: Wild type soma
GSE171199
Regulation
logFC: -8.32E-01
p-value: 2.90E-02
Result 4 indicating the AK4 expression regulated by METTL3
Cell Line LX2 cell line CVCL_5792
Condition Healthy Homo sapiens
Treatment: shMETTL3 LX2 cells
Control: shLuc LX2 cells
GSE207909
Regulation
logFC: 1.30E+00
p-value: 3.26E-30
Result 5 indicating the AK4 expression regulated by METTL3
Cell Line mouse embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- ESCs
Control: Wild type ESCs
GSE145309
Regulation
logFC: -1.01E+00
p-value: 6.30E-151
Result 6 indicating the AK4 expression regulated by METTL3
Cell Line E14.5 LSK cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout E14.5 LSK cells
Control: Wild type E14.5 LSK cells
GSE148882
Regulation
logFC: 1.25E+00
p-value: 7.15E-17
Result 7 indicating the AK4 expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout ES cells
Control: Wild type ES cells
GSE157262
Regulation
logFC: -7.72E-01
p-value: 1.08E-03
Result 8 indicating the AK4 expression regulated by METTL3
Cell Line Th1 cell line CVCL_5J51
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Th1 cells
Control: Wild type splenic Th1 cells
GSE129648
Regulation
logFC: 2.85E+00
p-value: 2.25E-02
Result 9 indicating the AK4 expression regulated by METTL3
Cell Line Mesenchymal stem cell line
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mesenchymal stem cells
Control: Wild type mesenchymal stem cells
GSE114933
Regulation
logFC: -1.02E+00
p-value: 2.87E-02