Results indicating the target gene (HMGA2 ) expression regulated by m6A regulator (METTL3 )
2B33: Malignant haematopoietic neoplasm
In total 1 results
Result 1 indicating the HMGA2 expression regulated by METTL3
Cell Line Raw 264.7 cell line CVCL_0493
Condition Leukemia Mus musculus
Treatment: METTL3 knockout Raw 264.7 cells
Control: Wild type Raw 264.7 cells
GSE162248
Regulation
logFC: -7.15E-01
p-value: 4.46E-21
2B90: Colon cancer
In total 1 results
Result 1 indicating the HMGA2 expression regulated by METTL3
Cell Line CT26 cell line CVCL_7254
Condition Colon adenocarcinoma Mus musculus
Treatment: METTL3 knockout CT26 cells
Control: CT26 cells
GSE142589
Regulation
logFC: -1.20E+00
p-value: 8.49E-04
2B91: Colorectal cancer
In total 1 results
Result 1 indicating the HMGA2 expression regulated by METTL3
Cell Line Caco-2 cell line CVCL_0025
Condition Colorectal adenocarcinoma Homo sapiens
Treatment: shMETTL3 Caco-2 cells
Control: shNTC Caco-2 cells
GSE167075
Regulation
logFC: 7.84E-01
p-value: 1.68E-53
Healthy
In total 8 results
Result 1 indicating the HMGA2 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
GSE198513
Regulation
logFC: -1.01E+00
p-value: 6.84E-25
Result 2 indicating the HMGA2 expression regulated by METTL3
Cell Line Cerebral cortex
Condition Healthy Mus musculus
Treatment: FTO (f/f, Emx1-cre) cerebral cortex
Control: Wild type cerebral cortex
GSE154992
Regulation
logFC: 1.70E+00
p-value: 8.42E-08
Result 3 indicating the HMGA2 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3-deficient liver
Control: Wild type liver cells
GSE197800
Regulation
logFC: 2.73E+00
p-value: 4.65E-02
Result 4 indicating the HMGA2 expression regulated by METTL3
Cell Line LX2 cell line CVCL_5792
Condition Healthy Homo sapiens
Treatment: shMETTL3 LX2 cells
Control: shLuc LX2 cells
GSE207909
Regulation
logFC: 4.44E+00
p-value: 5.85E-138
Result 5 indicating the HMGA2 expression regulated by METTL3
Cell Line ARPE-19 cell line CVCL_0145
Condition Healthy Homo sapiens
Treatment: shMETTL3 ARPE-19 cells
Control: shControl ARPE-19 cells
GSE202017
Regulation
logFC: -1.46E+00
p-value: 3.06E-05
Result 6 indicating the HMGA2 expression regulated by METTL3
Cell Line HUVEC cell line
Condition Healthy Homo sapiens
Treatment: shMETTL3 HUVEC cells
Control: shScramble HUVEC cells
GSE157544
Regulation
logFC: -9.22E-01
p-value: 1.29E-04
Result 7 indicating the HMGA2 expression regulated by METTL3
Cell Line mouse embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- ESCs
Control: Wild type ESCs
GSE145309
Regulation
logFC: 9.77E-01
p-value: 5.62E-52
Result 8 indicating the HMGA2 expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout ESCs
Control: Wild type ESCs
GSE146466
Regulation
logFC: -5.94E-01
p-value: 5.43E-04