General Information of the m6A Regulator (ID: REG00023)
Regulator Name YTH domain-containing protein 2 (YTHDC2)
Synonyms
3'-5' RNA helicase YTHDC2; hYTHDC2
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Gene Name YTHDC2
Regulator Type ERASER READER WRITER
Regulator Link Click to View Full Information of This Regulator
Full List of Target Gene(s) of This m6A Regulator ( Full Data Download )
Protein coding
Gene with protein product
In total 459 target gene(s)
Actin related protein T1 (ACTRT1) [1]
HGNC ID HGNC:24027
Ensembl ID ENSG00000123165
Uniprot ID ACTT1_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Acylphosphatase 2 (ACYP2) [1]
HGNC ID HGNC:180
Ensembl ID ENSG00000170634
Uniprot ID ACYP2_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
ADAM metallopeptidase domain 28 (ADAM28) [1]
HGNC ID HGNC:206
Ensembl ID ENSG00000042980
Uniprot ID ADA28_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
ADP ribosylation factor guanine nucleotide exchange factor 1 (ARFGEF1) [1]
HGNC ID HGNC:15772
Ensembl ID ENSG00000066777
Uniprot ID BIG1_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Alanyl-tRNA synthetase domain containing 1 (AARSD1) [1]
HGNC ID HGNC:28417
Ensembl ID ENSG00000266967
Uniprot ID AASD1_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Aldo-keto reductase family 7 member A2 (AKR7A2) [1]
HGNC ID HGNC:389
Ensembl ID ENSG00000053371
Uniprot ID ARK72_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Angiogenin (ANG) [1]
HGNC ID HGNC:483
Ensembl ID ENSG00000214274
Uniprot ID ANGI_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Ankyrin repeat domain 30B like (ANKRD30BL) [1]
HGNC ID HGNC:35167
Ensembl ID ENSG00000163046
Uniprot ID A30BL_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Arachidonate lipoxygenase 3 (ALOXE3) [1]
HGNC ID HGNC:13743
Ensembl ID ENSG00000179148
Uniprot ID LOXE3_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
ArfGAP with dual PH domains 1 (ADAP1) [1]
HGNC ID HGNC:16486
Ensembl ID ENSG00000105963
Uniprot ID ADAP1_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Pseudogene
Pseudogene
In total 11 target gene(s)
Caspase 16, pseudogene (CASP16P) [1]
HGNC ID HGNC:27290
Ensembl ID ENSG00000228146
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
CTAGE family member 11, pseudogene (CTAGE11P) [1]
HGNC ID HGNC:37293
Ensembl ID ENSG00000214249
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Family with sequence similarity 86 member C2, pseudogene (FAM86C2P) [1]
HGNC ID HGNC:42392
Ensembl ID ENSG00000160172
Uniprot ID F86C2_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
FSHD region gene 2 family member E, pseudogene (FRG2EP) [1]
HGNC ID HGNC:51365
Ensembl ID ENSG00000282842
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Leucine decarboxylase 1, pseudogene (LINC01225) [1]
HGNC ID HGNC:49677
Ensembl ID ENSG00000260386
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MLLT10 pseudogene 1 (MLLT10P1) [1]
HGNC ID HGNC:15794
Ensembl ID ENSG00000238151
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MT-RNR2 like 1 (pseudogene) (MTRNR2L1) [1]
HGNC ID HGNC:37155
Ensembl ID ENSG00000256618
Uniprot ID HMN1_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MT-RNR2 like 8 (pseudogene) (MTRNR2L8) [1]
HGNC ID HGNC:37165
Ensembl ID ENSG00000255823
Uniprot ID HMN8_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
PAFAH1B2 pseudogene 2 (LOC643711) [1]
HGNC ID HGNC:54906
Ensembl ID ENSG00000257501
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
PDE4DIP pseudogene 4 (LOC101929798) [1]
HGNC ID HGNC:55083
Ensembl ID ENSG00000275585
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Long non-coding
Long non-coding RNA
In total 40 target gene(s)
B4GAT1 divergent transcript (LOC102724064) [1]
HGNC ID HGNC:56070
Ensembl ID ENSG00000255468
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
DIAPH2 antisense RNA 1 (DIAPH2-AS1) [1]
HGNC ID HGNC:16972
Ensembl ID ENSG00000236256
Uniprot ID EPAG_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
FAM167A antisense RNA 1 (FAM167A-AS1) [1]
HGNC ID HGNC:15548
Ensembl ID ENSG00000184608
Uniprot ID FAAS1_HUMAN
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
FOXN3 antisense RNA 2 (FOXN3-AS2) [1]
HGNC ID HGNC:30119
Ensembl ID ENSG00000259073
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Long intergenic non-protein coding RNA 1470 (LINC01470) [1]
HGNC ID HGNC:51105
Ensembl ID ENSG00000249484
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Long intergenic non-protein coding RNA 1570 (LINC01570) [1]
HGNC ID HGNC:51382
Ensembl ID ENSG00000260338
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Long intergenic non-protein coding RNA 1623 (LINC01623) [1]
HGNC ID HGNC:52050
Ensembl ID ENSG00000225595
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Long intergenic non-protein coding RNA 163 (LINC00163) [1]
HGNC ID HGNC:33165
Ensembl ID ENSG00000234880
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Long intergenic non-protein coding RNA 1793 (LINC01793) [1]
HGNC ID HGNC:52583
Ensembl ID ENSG00000222030
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Long intergenic non-protein coding RNA 1815 (LINC01815) [1]
HGNC ID HGNC:52619
Ensembl ID ENSG00000235519
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Short non-coding
Micro RNA
In total 8 target gene(s)
MicroRNA 1976 (MIR1976) [1]
HGNC ID HGNC:37064
Ensembl ID ENSG00000238705
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 3675 (MIR3675) [1]
HGNC ID HGNC:38973
Ensembl ID ENSG00000263811
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 4274 (MIR4274) [1]
HGNC ID HGNC:38194
Ensembl ID ENSG00000266690
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 4468 (MIR4468) [1]
HGNC ID HGNC:41533
Ensembl ID ENSG00000284028
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 5188 (MIR5188) [1]
HGNC ID HGNC:43502
Ensembl ID ENSG00000265345
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 604 (MIR604) [1]
HGNC ID HGNC:32860
Ensembl ID ENSG00000207612
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 663b (MIR663B) [1]
HGNC ID HGNC:35270
Ensembl ID ENSG00000221288
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 8068 (MIR8068) [1]
HGNC ID HGNC:50238
Ensembl ID ENSG00000273912
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Misc RNA
In total 2 target gene(s)
Ribonuclease P RNA component H1 (RPPH1) [1]
HGNC ID HGNC:19273
Ensembl ID ENSG00000277209
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA component of mitochondrial RNA processing endoribonuclease (RMRP) [1]
HGNC ID HGNC:10031
Ensembl ID ENSG00000277027
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Ribosomal RNA
In total 5 target gene(s)
RNA, 18S ribosomal 5 (RNA18S5) [1]
HGNC ID HGNC:37657
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 28S ribosomal 5 (RNA28S5) [1]
HGNC ID HGNC:37659
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 45S pre-ribosomal 5 (RNA45S5) [1]
HGNC ID HGNC:44273
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 5.8S ribosomal 5 (RNA5-8S5) [1]
HGNC ID HGNC:37660
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 5S ribosomal 9 (RNA5S9) [1]
HGNC ID HGNC:34370
Ensembl ID ENSG00000201321
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Small nuclear RNA
In total 10 target gene(s)
RNA, U1 small nuclear 4 (RNU1-4) [1]
HGNC ID HGNC:10128
Ensembl ID ENSG00000207389
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, U11 small nuclear (RNU11) [1]
HGNC ID HGNC:10108
Ensembl ID ENSG00000274978
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, U4 small nuclear 2 (RNU4-2) [1]
HGNC ID HGNC:10193
Ensembl ID ENSG00000202538
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, U6atac small nuclear (RNU6ATAC) [1]
HGNC ID HGNC:34017
Ensembl ID ENSG00000221676
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, variant U1 small nuclear 1 (RNVU1-1) [1]
HGNC ID HGNC:10133
Ensembl ID ENSG00000207340
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, variant U1 small nuclear 14 (RNVU1-14) [1]
HGNC ID HGNC:48319
Ensembl ID ENSG00000207501
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, variant U1 small nuclear 15 (RNVU1-15) [1]
HGNC ID HGNC:48320
Ensembl ID ENSG00000207205
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, variant U1 small nuclear 17 (RNVU1-17) [1]
HGNC ID HGNC:48322
Ensembl ID ENSG00000207349
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, variant U1 small nuclear 19 (RNVU1-19) [1]
HGNC ID HGNC:48324
Ensembl ID ENSG00000275538
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, variant U1 small nuclear 6 (RNVU1-6) [1]
HGNC ID HGNC:48314
Ensembl ID ENSG00000201558
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Small nucleolar RNA
In total 8 target gene(s)
Small Cajal body-specific RNA 2 (SCARNA2) [1]
HGNC ID HGNC:32558
Ensembl ID ENSG00000278249
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small Cajal body-specific RNA 28 (SCARNA28) [1]
HGNC ID HGNC:50388
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small nucleolar RNA, C/D box 118 (SNORD118) [1]
HGNC ID HGNC:32952
Ensembl ID ENSG00000200463
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small nucleolar RNA, C/D box 133 (SNORD133) [1]
HGNC ID HGNC:50414
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small nucleolar RNA, C/D box 3D (SNORD3D) [1]
HGNC ID HGNC:33192
Ensembl ID ENSG00000277947
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small nucleolar RNA, C/D box 56 (SNORD56) [1]
HGNC ID HGNC:10206
Ensembl ID ENSG00000229686
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small nucleolar RNA, C/D box 97 (SNORD97) [1]
HGNC ID HGNC:32760
Ensembl ID ENSG00000238622
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small nucleolar RNA, H/ACA box 89 (SNORA89) [1]
HGNC ID HGNC:50393
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Vault RNA
In total 3 target gene(s)
Vault RNA 1-1 (VTRNA1-1) [1]
HGNC ID HGNC:12654
Ensembl ID ENSG00000199990
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Vault RNA 1-2 (VTRNA1-2) [1]
HGNC ID HGNC:12655
Ensembl ID ENSG00000202111
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Vault RNA 1-3 (VTRNA1-3) [1]
HGNC ID HGNC:12656
Ensembl ID ENSG00000202515
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Y RNA
In total 1 target gene(s)
RNA, Ro60-associated Y1 (RNY1) [1]
HGNC ID HGNC:10242
Ensembl ID ENSG00000201098
Method iCLIP-seq GSE78030; GSE86214
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
References
Ref 1 m(6)A RNA methylation promotes XIST-mediated transcriptional repression. Nature. 2016 Sep 15;537(7620):369-373. doi: 10.1038/nature19342. Epub 2016 Sep 7.
Ref 2 m(6)A in mRNA coding regions promotes translation via the RNA helicase-containing YTHDC2. Nat Commun. 2019 Nov 25;10(1):5332.