General Information of the m6A Regulator (ID: REG00012)
Regulator Name Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)
Synonyms
IGF2 mRNA-binding protein 1; IMP-1; IMP1; Coding region determinant-binding protein; CRD-BP; IGF-II mRNA-binding protein 1; VICKZ family member 1; Zipcode-binding protein 1; ZBP-1; CRDBP; VICKZ1; ZBP1
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Gene Name IGF2BP1
Regulator Type ERASER READER WRITER
Regulator Link Click to View Full Information of This Regulator
Full List of Target Gene(s) of This m6A Regulator ( Full Data Download )
Protein coding
Gene with protein product
In total 13741 target gene(s)
3-oxoacid CoA-transferase 1 (OXCT1) [1]
HGNC ID HGNC:8527
Ensembl ID ENSG00000083720
Uniprot ID SCOT1_HUMAN
Method RIP-seq logFC: 1.01E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Acidic residue methyltransferase 1 (ARMT1) [1]
HGNC ID HGNC:17872
Ensembl ID ENSG00000146476
Uniprot ID ARMT1_HUMAN
Method RIP-seq logFC: 2.18E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Acylglycerol kinase (AGK) [1]
HGNC ID HGNC:21869
Ensembl ID ENSG00000006530
Uniprot ID AGK_HUMAN
Method RIP-seq logFC: 1.02E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
ADP ribosylation factor like GTPase 2 binding protein (ARL2BP) [1]
HGNC ID HGNC:17146
Ensembl ID ENSG00000102931
Uniprot ID AR2BP_HUMAN
Method RIP-seq logFC: 3.62E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
ADP ribosylation factor like GTPase 6 (ARL6) [1]
HGNC ID HGNC:13210
Ensembl ID ENSG00000113966
Uniprot ID ARL6_HUMAN
Method RIP-seq logFC: 1.09E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Alpha and gamma adaptin binding protein (AAGAB) [1]
HGNC ID HGNC:25662
Ensembl ID ENSG00000103591
Uniprot ID AAGAB_HUMAN
Method RIP-seq logFC: 1.25E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase (AASDHPPT) [1]
HGNC ID HGNC:14235
Ensembl ID ENSG00000149313
Uniprot ID ADPPT_HUMAN
Method RIP-seq logFC: 1.59E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Ankyrin repeat domain 36B (ANKRD36B) [1]
HGNC ID HGNC:29333
Ensembl ID ENSG00000196912
Uniprot ID AN36B_HUMAN
Method RIP-seq logFC: 1.22E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Asparaginyl-tRNA synthetase 2, mitochondrial (NARS2) [1]
HGNC ID HGNC:26274
Ensembl ID ENSG00000137513
Uniprot ID SYNM_HUMAN
Method RIP-seq logFC: 1.39E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
ATP synthase F1 subunit alpha (ATP5A1) [1]
HGNC ID HGNC:823
Ensembl ID ENSG00000152234
Uniprot ID ATPA_HUMAN
Method RIP-seq logFC: 1.05E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Pseudogene
Immunoglobulin pseudogene
In total 1 target gene(s)
Immunoglobulin lambda variable 1-41 (pseudogene) (IGLV1-41) [6]
HGNC ID HGNC:5878
Ensembl ID ENSG00000253818
Method RNA-seq GSE116133
Condition knock down
Evidence logFC: -1.877216668; p-value: 0.044439907
Cell Line Huh-7 cell line Hepatocellular carcinoma Homo sapiens CVCL_0336
Click to Download All Target Gene of This Genetic Class
Pseudogene
In total 1532 target gene(s)
ADAM metallopeptidase domain 1A (pseudogene) (ADAM1A) [1]
HGNC ID HGNC:187
Ensembl ID ENSG00000229186
Method RIP-seq logFC: 2.17E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Adenylate kinase 4 pseudogene 1 (AK4P1) [1]
HGNC ID HGNC:364
Ensembl ID ENSG00000263535
Method RIP-seq logFC: 1.10E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
ALG1 chitobiosyldiphosphodolichol beta-mannosyltransferase like (ALG1L) [1]
HGNC ID HGNC:33721
Ensembl ID ENSG00000189366
Uniprot ID ALG1L_HUMAN
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Ankyrin repeat domain 18D, pseudogene (ANKRD18DP) [1]
HGNC ID HGNC:28016
Ensembl ID ENSG00000226435
Method RIP-seq logFC: 1.57E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Ankyrin repeat domain 20 family member A2, pseudogene (ANKRD20A2) [1]
HGNC ID HGNC:31979
Ensembl ID ENSG00000183148
Uniprot ID A20A2_HUMAN
Method RIP-seq logFC: 1.02E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
ATP binding cassette subfamily A member 11, pseudogene (ABCA11P) [1]
HGNC ID HGNC:31
Ensembl ID ENSG00000251595
Method RIP-seq logFC: 2.76E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
ATP synthase F1 subunit epsilon pseudogene 2 (ATP5EP2) [1]
HGNC ID HGNC:34026
Ensembl ID ENSG00000180389
Uniprot ID AT5EL_HUMAN
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
ATP synthase peripheral stalk-membrane subunit b pseudogene 1 (ATP5F1P1) [1]
HGNC ID HGNC:39742
Ensembl ID ENSG00000224451
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
BANF1 pseudogene 3 (BANF1P3) [1]
HGNC ID HGNC:43883
Ensembl ID ENSG00000237758
Method RIP-seq logFC: 2.00E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Centromere protein C pseudogene 1 (CENPCP1) [1]
HGNC ID HGNC:1855
Ensembl ID ENSG00000226982
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Long non-coding
Long non-coding RNA
In total 1707 target gene(s)
ADNP antisense RNA 1 (ADNP-AS1) [1]
HGNC ID HGNC:51227
Ensembl ID ENSG00000259456
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
ANKRD10 intronic transcript 1 (ANKRD10-IT1) [1]
HGNC ID HGNC:39891
Ensembl ID ENSG00000229152
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
DCUN1D2 antisense RNA (DCUN1D2-AS) [1]
HGNC ID HGNC:39889
Ensembl ID ENSG00000233613
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
DDIT4 antisense RNA 1 (RP11-442H21.2) [1]
HGNC ID HGNC:52379
Ensembl ID ENSG00000269926
Method RIP-seq logFC: 1.00E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
DIAPH1 antisense RNA 1 (CTD-2024I7.13) [1]
HGNC ID HGNC:40177
Ensembl ID ENSG00000246422
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
EHD4 antisense RNA 1 (EHD4-AS1) [1]
HGNC ID HGNC:51418
Ensembl ID ENSG00000259883
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
HDAC4 antisense RNA 1 (AC062017.1) [1]
HGNC ID HGNC:54064
Ensembl ID ENSG00000222020
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
HOXC cluster antisense RNA 1 (HOXC-AS1) [1]
HGNC ID HGNC:43749
Ensembl ID ENSG00000250451
Method RIP-seq logFC: 1.37E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
KCNMB2 antisense RNA 1 (KCNMB2-AS1) [1]
HGNC ID HGNC:51409
Ensembl ID ENSG00000237978
Method RIP-seq logFC: 1.25E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Long intergenic non-protein coding RNA 1338 (LINC01338) [1]
HGNC ID HGNC:50547
Ensembl ID ENSG00000281327
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Short non-coding
Micro RNA
In total 786 target gene(s)
MicroRNA 3648-1 (MIR3648-1) [1]
HGNC ID HGNC:38941
Ensembl ID ENSG00000275708
Method RIP-seq logFC: 1.16E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 3648-2 (MIR3648-2) [1]
HGNC ID HGNC:50843
Ensembl ID ENSG00000264462
Method RIP-seq logFC: 1.16E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 3651 (MIR3651) [1]
HGNC ID HGNC:38897
Ensembl ID ENSG00000281156
Method RIP-seq logFC: 3.63E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 101-2 (MIR101-2) [1]
HGNC ID HGNC:31489
Ensembl ID ENSG00000199065
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 103a-1 (MIR103A1) [1]
HGNC ID HGNC:31490
Ensembl ID ENSG00000199035
Method eCLIP-seq GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 103a-2 (MIR103A2) [1]
HGNC ID HGNC:31491
Ensembl ID ENSG00000199024
Method eCLIP-seq GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 103b-1 (MIR103B1) [1]
HGNC ID HGNC:35384
Ensembl ID ENSG00000283612
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 103b-2 (MIR103B2) [1]
HGNC ID HGNC:35385
Ensembl ID ENSG00000283320
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 106b (MIR106B) [1]
HGNC ID HGNC:31495
Ensembl ID ENSG00000208036
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MicroRNA 1180 (MIR1180) [1]
HGNC ID HGNC:35261
Ensembl ID ENSG00000221540
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Misc RNA
In total 5 target gene(s)
Telomerase RNA component (TERC) [1]
HGNC ID HGNC:11727
Ensembl ID ENSG00000270141
Method RIP-seq logFC: 1.28E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Ribonuclease P RNA component H1 (RPPH1) [1]
HGNC ID HGNC:19273
Ensembl ID ENSG00000277209
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA component of mitochondrial RNA processing endoribonuclease (RMRP) [1]
HGNC ID HGNC:10031
Ensembl ID ENSG00000277027
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small NF90 (ILF3) associated RNA A9 (SNAR-A9) [1]
HGNC ID HGNC:34312
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small NF90 (ILF3) associated RNA E (SNAR-E) [1]
HGNC ID HGNC:34325
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Ribosomal RNA
In total 22 target gene(s)
RNA, 5S ribosomal 1 (RNA5S1) [1]
HGNC ID HGNC:34362
Ensembl ID ENSG00000199352
Method RIP-seq logFC: 5.97E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 5S ribosomal 10 (RNA5S10) [1]
HGNC ID HGNC:34371
Ensembl ID ENSG00000199910
Method RIP-seq logFC: 5.97E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 5S ribosomal 11 (RNA5S11) [1]
HGNC ID HGNC:34372
Ensembl ID ENSG00000199334
Method RIP-seq logFC: 5.97E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 5S ribosomal 12 (RNA5S12) [1]
HGNC ID HGNC:34373
Ensembl ID ENSG00000199270
Method RIP-seq logFC: 5.97E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 5S ribosomal 13 (RNA5S13) [1]
HGNC ID HGNC:34374
Ensembl ID ENSG00000202526
Method RIP-seq logFC: 5.97E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 5S ribosomal 14 (RNA5S14) [1]
HGNC ID HGNC:34375
Ensembl ID ENSG00000201355
Method RIP-seq logFC: 5.97E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 5S ribosomal 15 (RNA5S15) [1]
HGNC ID HGNC:34376
Ensembl ID ENSG00000201925
Method RIP-seq logFC: 5.97E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 5S ribosomal 16 (RNA5S16) [1]
HGNC ID HGNC:34377
Ensembl ID ENSG00000202257
Method RIP-seq logFC: 5.97E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 5S ribosomal 17 (RNA5S17) [1]
HGNC ID HGNC:34378
Ensembl ID ENSG00000200370
Method RIP-seq logFC: 5.97E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, 5S ribosomal 2 (RNA5S2) [1]
HGNC ID HGNC:34363
Ensembl ID ENSG00000201588
Method RIP-seq logFC: 5.97E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Small nuclear RNA
In total 37 target gene(s)
RNA, U4 small nuclear 1 (RNU4-1) [1]
HGNC ID HGNC:10192
Ensembl ID ENSG00000200795
Method RIP-seq logFC: 2.60E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, U4 small nuclear 2 (RNU4-2) [1]
HGNC ID HGNC:10193
Ensembl ID ENSG00000202538
Method RIP-seq logFC: 1.84E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, U6 small nuclear 1 (RNU6-1) [1]
HGNC ID HGNC:10227
Ensembl ID ENSG00000206625
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, U6 small nuclear 2 (RNU6-2) [1]
HGNC ID HGNC:34270
Ensembl ID ENSG00000207357
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, U6 small nuclear 7 (RNU6-7) [1]
HGNC ID HGNC:34284
Ensembl ID ENSG00000201654
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, U6 small nuclear 8 (RNU6-8) [1]
HGNC ID HGNC:34285
Ensembl ID ENSG00000202337
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, U6 small nuclear 9 (RNU6-9) [1]
HGNC ID HGNC:34269
Ensembl ID ENSG00000207507
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, variant U1 small nuclear 2 (RNU1-13P) [1]
HGNC ID HGNC:48308
Ensembl ID ENSG00000238825
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, variant U1 small nuclear 32 (RNU1-106P) [1]
HGNC ID HGNC:48448
Ensembl ID ENSG00000207110
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, variant U1 small nuclear 7 (RNVU1-7) [1]
HGNC ID HGNC:37500
Ensembl ID ENSG00000206585
Method RIP-seq logFC: 2.39E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Small nucleolar RNA
In total 322 target gene(s)
Small Cajal body-specific RNA 10 (SCARNA10) [1]
HGNC ID HGNC:32567
Ensembl ID ENSG00000239002
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small Cajal body-specific RNA 13 (SCARNA13) [1]
HGNC ID HGNC:32570
Ensembl ID ENSG00000252481
Method RIP-seq logFC: 1.89E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small Cajal body-specific RNA 21 (SCARNA21) [1]
HGNC ID HGNC:32579
Ensembl ID ENSG00000252835
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small Cajal body-specific RNA 6 (SCARNA6) [1]
HGNC ID HGNC:32562
Ensembl ID ENSG00000251791
Method RIP-seq logFC: 1.81E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small Cajal body-specific RNA 7 (SCARNA7) [1]
HGNC ID HGNC:32563
Ensembl ID ENSG00000238741
Method RIP-seq logFC: 2.54E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small Cajal body-specific RNA 8 (SCARNA8) [1]
HGNC ID HGNC:32564
Ensembl ID ENSG00000251733
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small nucleolar RNA, C/D box 10 (SNORD10) [1]
HGNC ID HGNC:32706
Ensembl ID ENSG00000238917
Method RIP-seq logFC: 4.10E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small nucleolar RNA, C/D box 118 (SNORD118) [1]
HGNC ID HGNC:32952
Ensembl ID ENSG00000200463
Method RIP-seq logFC: 2.17E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small nucleolar RNA, C/D box 13 (SNORD13) [1]
HGNC ID HGNC:32711
Ensembl ID ENSG00000239039
Method RIP-seq logFC: 1.59E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Small nucleolar RNA, C/D box 15A (SNORD15A) [1]
HGNC ID HGNC:10114
Ensembl ID ENSG00000206941
Method RIP-seq logFC: 5.43E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Transfer RNA
In total 1 target gene(s)
Mitochondrially encoded tRNA-Ser (UCN) 1 (MT-TS1) [1]
HGNC ID HGNC:7497
Ensembl ID ENSG00000210151
Method RIP-seq logFC: 1.37E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Vault RNA
In total 4 target gene(s)
Vault RNA 1-1 (VTRNA1-1) [1]
HGNC ID HGNC:12654
Ensembl ID ENSG00000199990
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Vault RNA 1-2 (VTRNA1-2) [1]
HGNC ID HGNC:12655
Ensembl ID ENSG00000202111
Method eCLIP-seq GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Vault RNA 1-3 (VTRNA1-3) [1]
HGNC ID HGNC:12656
Ensembl ID ENSG00000202515
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Vault RNA 2-1 (VTRNA2-1) [1]
HGNC ID HGNC:37054
Ensembl ID ENSG00000270123
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
Y RNA
In total 2 target gene(s)
RNA, Ro60-associated Y3 (RNY3) [1]
HGNC ID HGNC:10243
Ensembl ID ENSG00000202354
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RNA, Ro60-associated Y1 (RNY1) [3]
HGNC ID HGNC:10242
Ensembl ID ENSG00000201098
Method RNA-seq GSE146805
Condition knock down
Evidence logFC: 0.639027158; p-value: 0.036011186
Cell Line PANC-1 cell line Pancreatic ductal adenocarcinoma Homo sapiens CVCL_0480
Click to Download All Target Gene of This Genetic Class
Other
Complex locus constituent
In total 10 target gene(s)
Protocadherin alpha 10 (PCDHA10) [1]
HGNC ID HGNC:8664
Ensembl ID ENSG00000250120
Uniprot ID PCDAA_HUMAN
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Protocadherin alpha subfamily C, 1 (PCDHAC1) [1]
HGNC ID HGNC:8676
Ensembl ID ENSG00000248383
Uniprot ID PCDC1_HUMAN
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Protocadherin alpha 3 (PCDHA3) [5]
HGNC ID HGNC:8669
Ensembl ID ENSG00000255408
Uniprot ID PCDA3_HUMAN
Method RNA-seq GSE161086
Condition knock down
Evidence logFC: -0.783417685; p-value: 0.006936404
Cell Line BE2C Healthy Homo sapiens .
Protocadherin alpha 4 (PCDHA4) [4]
HGNC ID HGNC:8670
Ensembl ID ENSG00000204967
Uniprot ID PCDA4_HUMAN
Method RNA-seq GSE146546
Condition knock out
Evidence logFC: -0.823876546; p-value: 0.021974315
Cell Line A549 Lung adenocarcinoma Homo sapiens CVCL_0023
UDP glucuronosyltransferase family 1 member A1 (UGT1A1) [6]
HGNC ID HGNC:12530
Ensembl ID ENSG00000241635
Uniprot ID UD11_HUMAN
Method RNA-seq GSE116133
Condition knock down
Evidence logFC: 0.788343173; p-value: 0.001211562
Cell Line Huh-7 cell line Hepatocellular carcinoma Homo sapiens CVCL_0336
UDP glucuronosyltransferase family 1 member A2, pseudogene (UGT1A2P) [4]
HGNC ID HGNC:12534
Ensembl ID ENSG00000228445
Method RNA-seq GSE146546
Condition knock out
Evidence logFC: -0.695193382; p-value: 0.034370901
Cell Line A549 Lung adenocarcinoma Homo sapiens CVCL_0023
UDP glucuronosyltransferase family 1 member A6 (UGT1A6) [6]
HGNC ID HGNC:12538
Ensembl ID ENSG00000167165
Uniprot ID UD16_HUMAN
Method RNA-seq GSE116133
Condition knock down
Evidence logFC: -0.962927811; p-value: 0.002564303
Cell Line Huh-7 cell line Hepatocellular carcinoma Homo sapiens CVCL_0336
UDP glucuronosyltransferase family 1 member A7 (UGT1A7) [6]
HGNC ID HGNC:12539
Ensembl ID ENSG00000244122
Uniprot ID UD17_HUMAN
Method RNA-seq GSE116133
Condition knock down
Evidence logFC: 0.71962342; p-value: 0.002448471
Cell Line Huh-7 cell line Hepatocellular carcinoma Homo sapiens CVCL_0336
UDP glucuronosyltransferase family 1 member A8 (UGT1A8) [6]
HGNC ID HGNC:12540
Ensembl ID ENSG00000242366
Uniprot ID UD18_HUMAN
Method RNA-seq GSE116133
Condition knock down
Evidence logFC: -1.363756264; p-value: 0.025732674
Cell Line Huh-7 cell line Hepatocellular carcinoma Homo sapiens CVCL_0336
UDP glucuronosyltransferase family 1 member A9 (UGT1A9) [4]
HGNC ID HGNC:12541
Ensembl ID ENSG00000241119
Uniprot ID UD19_HUMAN
Method RNA-seq GSE146546
Condition knock out
Evidence logFC: 1.590722944; p-value: 0.004785631
Cell Line A549 Lung adenocarcinoma Homo sapiens CVCL_0023
Click to Download All Target Gene of This Genetic Class
Endogenous retrovirus
In total 4 target gene(s)
Endogenous retrovirus group 48 member 1 (ERVH48-1) [1]
HGNC ID HGNC:17216
Ensembl ID ENSG00000233056
Uniprot ID SUPYN_HUMAN
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Endogenous retrovirus group K3 member 1 (ERVK3-1) [1]
HGNC ID HGNC:30466
Ensembl ID ENSG00000142396
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Endogenous retrovirus group K13 member 1 (ERVK13-1) [5]
HGNC ID HGNC:27548
Ensembl ID ENSG00000260565
Uniprot ID ENK13_HUMAN
Method RNA-seq GSE161086
Condition knock down
Evidence logFC: 0.72990027; p-value: 0.000491503
Cell Line BE2C Healthy Homo sapiens .
Endogenous retrovirus group K9, member 11 (ERVK9-11) [6]
HGNC ID HGNC:51160
Ensembl ID ENSG00000269486
Method RNA-seq GSE116133
Condition knock down
Evidence logFC: 1.033986296; p-value: 0.001633979
Cell Line Huh-7 cell line Hepatocellular carcinoma Homo sapiens CVCL_0336
Click to Download All Target Gene of This Genetic Class
Immunoglobulin gene
In total 4 target gene(s)
Immunoglobulin heavy variable 3-33 (IGHV3-33) [5]
HGNC ID HGNC:5596
Ensembl ID ENSG00000211955
Uniprot ID HV333_HUMAN
Method RNA-seq GSE161086
Condition knock down
Evidence logFC: -0.803351743; p-value: 0.0355388
Cell Line BE2C Healthy Homo sapiens .
Immunoglobulin lambda constant 2 (IGLC2) [4]
HGNC ID HGNC:5856
Ensembl ID ENSG00000211677
Uniprot ID IGLC2_HUMAN
Method RNA-seq GSE146802
Condition knock down
Evidence logFC: -3.762772972; p-value: 2.88E-07
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
Immunoglobulin lambda variable 1-51 (IGLV1-51) [5]
HGNC ID HGNC:5882
Ensembl ID ENSG00000211644
Uniprot ID LV151_HUMAN
Method RNA-seq GSE161086
Condition knock down
Evidence logFC: -1.102231871; p-value: 0.010930085
Cell Line BE2C Healthy Homo sapiens .
Immunoglobulin lambda variable 5-52 (IGLV5-52) [5]
HGNC ID HGNC:5926
Ensembl ID ENSG00000211643
Uniprot ID LV552_HUMAN
Method RNA-seq GSE161086
Condition knock down
Evidence logFC: -1.056166791; p-value: 0.0198791
Cell Line BE2C Healthy Homo sapiens .
Click to Download All Target Gene of This Genetic Class
Protocadherin
In total 26 target gene(s)
Protocadherin beta 1 (PCDHB1) [1]
HGNC ID HGNC:8680
Ensembl ID ENSG00000171815
Uniprot ID PCDB1_HUMAN
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Protocadherin beta 14 (PCDHB14) [1]
HGNC ID HGNC:8685
Ensembl ID ENSG00000120327
Uniprot ID PCDBE_HUMAN
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Protocadherin beta 2 (PCDHB2) [1]
HGNC ID HGNC:8687
Ensembl ID ENSG00000112852
Uniprot ID PCDB2_HUMAN
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Protocadherin gamma subfamily C, 5 (PCDHGC5) [1]
HGNC ID HGNC:8718
Ensembl ID ENSG00000240764
Uniprot ID PCDGM_HUMAN
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Protocadherin beta 13 (PCDHB13) [6]
HGNC ID HGNC:8684
Ensembl ID ENSG00000187372
Uniprot ID PCDBD_HUMAN
Method RNA-seq GSE116059
Condition knock down
Evidence logFC: -0.800286049; p-value: 0.012042776
Cell Line ES-2 cell line Ovarian cancer Homo sapiens CVCL_3509
Protocadherin beta 15 (PCDHB15) [6]
HGNC ID HGNC:8686
Ensembl ID ENSG00000113248
Uniprot ID PCDBF_HUMAN
Method RNA-seq GSE116059
Condition knock down
Evidence logFC: -0.720353165; p-value: 0.005205251
Cell Line ES-2 cell line Ovarian cancer Homo sapiens CVCL_3509
Protocadherin beta 5 (PCDHB5) [2]
HGNC ID HGNC:8690
Ensembl ID ENSG00000113209
Uniprot ID PCDB5_HUMAN
Method RNA-seq GSE109604
Condition knock down
Evidence logFC: -1.082257881; p-value: 0.002081071
Cell Line ES-2 cell line Ovarian cancer Homo sapiens CVCL_3509
Protocadherin beta 6 (PCDHB6) [6]
HGNC ID HGNC:8691
Ensembl ID ENSG00000113211
Uniprot ID PCDB6_HUMAN
Method RNA-seq GSE116059
Condition knock down
Evidence logFC: -0.599575404; p-value: 0.013771507
Cell Line ES-2 cell line Ovarian cancer Homo sapiens CVCL_3509
Protocadherin beta 8 (PCDHB8) [6]
HGNC ID HGNC:8693
Ensembl ID ENSG00000120322
Uniprot ID PCDB8_HUMAN
Method RNA-seq GSE116059
Condition knock down
Evidence logFC: -0.730533913; p-value: 0.004810916
Cell Line ES-2 cell line Ovarian cancer Homo sapiens CVCL_3509
Protocadherin gamma subfamily A, 1 (PCDHGA1) [2]
HGNC ID HGNC:8696
Ensembl ID ENSG00000204956
Uniprot ID PCDG1_HUMAN
Method RNA-seq GSE109604
Condition knock down
Evidence logFC: -0.876544611; p-value: 0.014466132
Cell Line ES-2 cell line Ovarian cancer Homo sapiens CVCL_3509
Click to Download All Target Gene of This Genetic Class
Readthrough
In total 51 target gene(s)
BCL2L2-PABPN1 readthrough (BCL2L2-PABPN1) [1]
HGNC ID HGNC:42959
Ensembl ID ENSG00000258643
Uniprot ID B2CL2_HUMAN
Method RIP-seq logFC: 2.66E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
BIVM-ERCC5 readthrough (BIVM-ERCC5) [1]
HGNC ID HGNC:43690
Ensembl ID ENSG00000270181
Method RIP-seq logFC: 1.14E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
CENPS-CORT readthrough (APITD1-CORT) [1]
HGNC ID HGNC:38843
Ensembl ID ENSG00000251503
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
DTX2P1-UPK3BP1-PMS2P11 readthrough, transcribed pseudogene (DTX2P1-UPK3BP1-PMS2P11) [1]
HGNC ID HGNC:42360
Ensembl ID ENSG00000265479
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
FMC1-LUC7L2 readthrough (C7orf55-LUC7L2) [1]
HGNC ID HGNC:44671
Ensembl ID ENSG00000269955
Method RIP-seq logFC: 1.63E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
FPGT-TNNI3K readthrough (FPGT-TNNI3K) [1]
HGNC ID HGNC:42952
Ensembl ID ENSG00000259030
Method RIP-seq logFC: 1.61E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
INMT-MINDY4 readthrough (NMD candidate) (INMT-FAM188B) [1]
HGNC ID HGNC:41995
Ensembl ID ENSG00000254959
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
NME1-NME2 readthrough (NME1-NME2) [1]
HGNC ID HGNC:33531
Ensembl ID ENSG00000011052
Method RIP-seq logFC: 1.98E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
PEDS1-UBE2V1 readthrough (TMEM189-UBE2V1) [1]
HGNC ID HGNC:33521
Ensembl ID ENSG00000124208
Method RIP-seq logFC: 1.75E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
RAB4B-EGLN2 readthrough (NMD candidate) (RAB4B-EGLN2) [1]
HGNC ID HGNC:44465
Ensembl ID ENSG00000171570
Method RIP-seq logFC: Inf GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Click to Download All Target Gene of This Genetic Class
T cell receptor gene
In total 5 target gene(s)
T cell receptor alpha constant (TRAC) [5]
HGNC ID HGNC:12029
Ensembl ID ENSG00000277734
Uniprot ID TRAC_HUMAN
Method RNA-seq GSE161086
Condition knock down
Evidence logFC: 0.752716327; p-value: 0.001742881
Cell Line BE2C Healthy Homo sapiens .
T cell receptor alpha joining 32 (TRAJ32) [5]
HGNC ID HGNC:12062
Ensembl ID ENSG00000211857
Method RNA-seq GSE161086
Condition knock down
Evidence logFC: 0.914671951; p-value: 0.001238512
Cell Line BE2C Healthy Homo sapiens .
T cell receptor beta joining 2-2P (non-functional) (TRBJ2-2P) [6]
HGNC ID HGNC:12170
Ensembl ID ENSG00000211766
Method RNA-seq GSE116059
Condition knock down
Evidence logFC: -2.482800946; p-value: 0.001274954
Cell Line ES-2 cell line Ovarian cancer Homo sapiens CVCL_3509
T cell receptor beta variable 13 (TRBV13) [4]
HGNC ID HGNC:12188
Ensembl ID ENSG00000276405
Uniprot ID TVB13_HUMAN
Method RNA-seq GSE146803
Condition knock down
Evidence logFC: -1.221021829; p-value: 0.009422013
Cell Line MV3 cell line Amelanotic melanoma Homo sapiens CVCL_W280
T cell receptor beta variable 29/OR9-2 (non-functional) (TRBV29OR9-2) [6]
HGNC ID HGNC:12211
Ensembl ID ENSG00000223394
Method RNA-seq GSE116059
Condition knock down
Evidence logFC: -1.312634507; p-value: 0.022121906
Cell Line ES-2 cell line Ovarian cancer Homo sapiens CVCL_3509
Click to Download All Target Gene of This Genetic Class
Unknown
In total 12 target gene(s)
Ribosomal protein SA pseudogene 58 (RPSAP58) [1]
HGNC ID HGNC:36809
Ensembl ID ENSG00000225178
Method RIP-seq logFC: 4.77E+00 GSE90639
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Adhesion G protein-coupled receptor F2 (ADGRF2) [1]
HGNC ID HGNC:18991
Ensembl ID ENSG00000164393
Uniprot ID AGRF2_HUMAN
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Chromosome 1 putative open reading frame 220 (C1orf220) [1]
HGNC ID HGNC:33805
Ensembl ID ENSG00000213057
Uniprot ID CA220_HUMAN
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Chromosome 10 putative open reading frame 55 (C10orf55) [1]
HGNC ID HGNC:31008
Ensembl ID ENSG00000222047
Uniprot ID CJ055_HUMAN
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
elongin A3, pseudogene (TCEB3C) [1]
HGNC ID HGNC:24617
Ensembl ID ENSG00000288631
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Long intergenic non-protein coding RNA 672 (LINC00672) [1]
HGNC ID HGNC:44353
Ensembl ID ENSG00000263874
Method eCLIP-seq GSE78507; GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
MYCN opposite strand (MYCNOS) [1]
HGNC ID HGNC:16911
Ensembl ID ENSG00000233718
Uniprot ID NCYM_HUMAN
Method eCLIP-seq GSE78507
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Zinc finger protein 883 (ZNF883) [1]
HGNC ID HGNC:27271
Ensembl ID ENSG00000228623
Uniprot ID ZN883_HUMAN
Method eCLIP-seq GSE92021
Cell Line HEK293T Normal Homo sapiens CVCL_0063
Chromosome 19 putative open reading frame 48 (C19orf48) [4]
HGNC ID HGNC:29667
Ensembl ID ENSG00000167747
Uniprot ID CS048_HUMAN
Method RNA-seq GSE146802
Condition knock down
Evidence logFC: -0.704195036; p-value: 0.013120715
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
Chromosome 22 putative open reading frame 46 (C22orf46) [4]
HGNC ID HGNC:26294
Ensembl ID ENSG00000184208
Uniprot ID CV046_HUMAN
Method RNA-seq GSE146802
Condition knock down
Evidence logFC: -1.976150832; p-value: 0.003625234
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
Click to Download All Target Gene of This Genetic Class
References
Ref 1 Recognition of RNA N(6)-methyladenosine by IGF2BP proteins enhances mRNA stability and translation. Nat Cell Biol. 2018 Mar;20(3):285-295. doi: 10.1038/s41556-018-0045-z. Epub 2018 Feb 23.
Ref 2 IGF2BP1 enhances an aggressive tumor cell phenotype by impairing miRNA-directed downregulation of oncogenic factors. Nucleic Acids Res. 2018 Jul 6;46(12):6285-6303.
Ref 3 IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression hallmark in cancer [IGF2BP1 KD in PANC-1 (total RNA)]
Ref 4 The oncofetal RNA-binding protein IGF2BP1 is a druggable, post-transcriptional super-enhancer of E2F-driven gene expression in cancer. Nucleic Acids Res. 2020 Sep 4;48(15):8576-8590.
Ref 5 IGF2BP1, a Conserved Regulator of RNA Turnover in Cancer. Front Mol Biosci. 2021 Mar 22;8:632219.
Ref 6 IGF2BP1 promotes SRF-dependent transcription in cancer in a m6A- and miRNA-dependent manner. Nucleic Acids Res. 2019 Jan 10;47(1):375-390. doi: 10.1093/nar/gky1012.