m6A Target Genes of This Regulator

General Information of the m6A Regulator (ID: REG00006)
Regulator Name Methyltransferase-like 14 (METTL14)
Synonyms
N6-adenosine-methyltransferase non-catalytic subunit; hMETTL14; KIAA1627
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Gene Name METTL14
Regulator Type ERASER READER WRITER
Regulator Link Click to View Full Information of This Regulator
Full List of Target Gene(s) of This m6A Regulator ( Full Data Download )
Protein coding
Gene with protein product
In total 3481 target gene(s)
1-acylglycerol-3-phosphate O-acyltransferase 3 (AGPAT3) [1]
HGNC ID HGNC:326
Ensembl ID ENSG00000160216
Uniprot ID PLCC_HUMAN
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: 1.015583179; p-value: 0.010953298
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
15-hydroxyprostaglandin dehydrogenase (HPGD) [2]
HGNC ID HGNC:5154
Ensembl ID ENSG00000164120
Uniprot ID PGDH_HUMAN
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 1.283808036; p-value: 0.004497545
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
2'-5'-oligoadenylate synthetase 1 (OAS1) [2]
HGNC ID HGNC:8086
Ensembl ID ENSG00000089127
Uniprot ID OAS1_HUMAN
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 0.590208105; p-value: 0.02715503
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
2'-5'-oligoadenylate synthetase like (OASL) [2]
HGNC ID HGNC:8090
Ensembl ID ENSG00000135114
Uniprot ID OASL_HUMAN
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 0.871612292; p-value: 0.006228615
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
24-dehydrocholesterol reductase (DHCR24) [1]
HGNC ID HGNC:2859
Ensembl ID ENSG00000116133
Uniprot ID DHC24_HUMAN
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: 2.774607122; p-value: 0.000175737
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
3'(2'), 5'-bisphosphate nucleotidase 1 (BPNT1) [2]
HGNC ID HGNC:1096
Ensembl ID ENSG00000162813
Uniprot ID BPNT1_HUMAN
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 0.819604802; p-value: 0.005344457
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
3'-phosphoadenosine 5'-phosphosulfate synthase 2 (PAPSS2) [2]
HGNC ID HGNC:8604
Ensembl ID ENSG00000198682
Uniprot ID PAPS2_HUMAN
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: -1.106052673; p-value: 0.000536431
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) [1]
HGNC ID HGNC:5006
Ensembl ID ENSG00000113161
Uniprot ID HMDH_HUMAN
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: 0.941076315; p-value: 0.019705495
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
3-hydroxy-3-methylglutaryl-CoA synthase 1 (HMGCS1) [1]
HGNC ID HGNC:5007
Ensembl ID ENSG00000112972
Uniprot ID HMCS1_HUMAN
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: 0.787472569; p-value: 0.009057911
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
3-hydroxy-3-methylglutaryl-CoA synthase 2 (HMGCS2) [1]
HGNC ID HGNC:5008
Ensembl ID ENSG00000134240
Uniprot ID HMCS2_HUMAN
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: -0.751502445; p-value: 0.006215967
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
Click to Download All Target Gene of This Genetic Class
Pseudogene
Pseudogene
In total 28 target gene(s)
5-hydroxytryptamine receptor 7 pseudogene 1 (HTR7P1) [2]
HGNC ID HGNC:30411
Ensembl ID ENSG00000183935
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 1.287190754; p-value: 0.002462879
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
AFG3 like matrix AAA peptidase subunit 1, pseudogene (AFG3L1P) [2]
HGNC ID HGNC:314
Ensembl ID ENSG00000223959
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 0.828226925; p-value: 1.35E-05
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
AMZ2 pseudogene 1 (AMZ2P1) [2]
HGNC ID HGNC:26491
Ensembl ID ENSG00000214174
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 1.965165449; p-value: 0.013033264
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
Annexin A2 pseudogene 1 (ANXA2P1) [2]
HGNC ID HGNC:538
Ensembl ID ENSG00000213406
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 0.599927987; p-value: 0.040399227
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
Annexin A2 pseudogene 2 (ANXA2P2) [2]
HGNC ID HGNC:539
Ensembl ID ENSG00000231991
Uniprot ID AXA2L_HUMAN
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: -7.246569436; p-value: 0.008876002
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
ATP binding cassette subfamily C member 13 (pseudogene) (ABCC13) [2]
HGNC ID HGNC:16022
Ensembl ID ENSG00000243064
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: -2.289128754; p-value: 1.41E-109
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
ATPase H+ transporting accessory protein 1 like (pseudogene) (ATP6AP1L) [2]
HGNC ID HGNC:28091
Ensembl ID ENSG00000205464
Uniprot ID VAS1L_HUMAN
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: -1.206873954; p-value: 0.011850311
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
Carbonic anhydrase 5B pseudogene 1 (CA5BP1) [2]
HGNC ID HGNC:29544
Ensembl ID ENSG00000186312
Uniprot ID CA5BL_HUMAN
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 0.771122375; p-value: 0.001206411
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
Caspase 16, pseudogene (CASP16P) [1]
HGNC ID HGNC:27290
Ensembl ID ENSG00000228146
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: -0.690240075; p-value: 0.049422781
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
CEA cell adhesion molecule 22, pseudogene (CEACAM22P) [2]
HGNC ID HGNC:38029
Ensembl ID ENSG00000230666
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 0.622185653; p-value: 0.01970801
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
Click to Download All Target Gene of This Genetic Class
Long non-coding
Long non-coding RNA
In total 84 target gene(s)
ANKRD10 intronic transcript 1 (ANKRD10-IT1) [1]
HGNC ID HGNC:39891
Ensembl ID ENSG00000229152
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: 9.723557072; p-value: 0.012826751
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
APOA1 antisense RNA (APOA1-AS) [1]
HGNC ID HGNC:40079
Ensembl ID ENSG00000235910
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: -1.548145485; p-value: 1.41E-05
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
BAZ1A antisense RNA 1 (BAZ1A-AS1) [1]
HGNC ID HGNC:55440
Ensembl ID ENSG00000258738
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: -1.240237706; p-value: 1.45E-22
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
C1QTNF1 antisense RNA 1 (C1QTNF1-AS1) [1]
HGNC ID HGNC:44351
Ensembl ID ENSG00000265096
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: -0.630403019; p-value: 8.65E-05
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
C2orf74 divergent transcript (C2orf74-DT) [1]
HGNC ID HGNC:27941
Ensembl ID ENSG00000212978
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: -0.687116048; p-value: 0.001211568
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
C6orf47 antisense RNA 1 (C6orf47-AS1) [1]
HGNC ID HGNC:39767
Ensembl ID ENSG00000227198
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: 0.676367193; p-value: 0.006573602
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
Cancer susceptibility 2 (CASC2) [2]
HGNC ID HGNC:22933
Ensembl ID ENSG00000177640
Uniprot ID CASC2_HUMAN
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 0.587395398; p-value: 0.003104922
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
CCDC18 antisense RNA 1 (CCDC18-AS1) [1]
HGNC ID HGNC:52262
Ensembl ID ENSG00000223745
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: -2.561765607; p-value: 0.00040836
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
CDKN2B antisense RNA 1 (CDKN2B-AS1) [1]
HGNC ID HGNC:34341
Ensembl ID ENSG00000240498
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: 1.681670924; p-value: 0.001316605
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
CFLAR antisense RNA 1 (CFLAR-AS1) [2]
HGNC ID HGNC:14437
Ensembl ID ENSG00000226312
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: -0.930649447; p-value: 0.047222484
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
Click to Download All Target Gene of This Genetic Class
Short non-coding
Micro RNA
In total 2 target gene(s)
MicroRNA 221 (MIR221) [2]
HGNC ID HGNC:31601
Ensembl ID ENSG00000207870
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 1.044152985; p-value: 0.004238443
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
MicroRNA 614 (MIR614) [2]
HGNC ID HGNC:32870
Ensembl ID ENSG00000283759
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 1.046519198; p-value: 0.009628725
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
Click to Download All Target Gene of This Genetic Class
Small nucleolar RNA
In total 1 target gene(s)
Small nucleolar RNA, C/D box 93 (SNORD93) [2]
HGNC ID HGNC:32755
Ensembl ID ENSG00000221740
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: -0.953600767; p-value: 0.008296716
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
Click to Download All Target Gene of This Genetic Class
Other
Complex locus constituent
In total 2 target gene(s)
Protocadherin alpha 3 (PCDHA3) [2]
HGNC ID HGNC:8669
Ensembl ID ENSG00000255408
Uniprot ID PCDA3_HUMAN
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: -0.894898363; p-value: 0.002698175
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
UDP glucuronosyltransferase family 1 member A1 (UGT1A1) [1]
HGNC ID HGNC:12530
Ensembl ID ENSG00000241635
Uniprot ID UD11_HUMAN
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: -2.7338212; p-value: 0.000126197
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
Click to Download All Target Gene of This Genetic Class
Protocadherin
In total 4 target gene(s)
Protocadherin beta 13 (PCDHB13) [1]
HGNC ID HGNC:8684
Ensembl ID ENSG00000187372
Uniprot ID PCDBD_HUMAN
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: -0.899090626; p-value: 0.001770559
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
Protocadherin beta 7 (PCDHB7) [1]
HGNC ID HGNC:8692
Ensembl ID ENSG00000113212
Uniprot ID PCDB7_HUMAN
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: -0.610876206; p-value: 0.027906864
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
Protocadherin beta 8 (PCDHB8) [1]
HGNC ID HGNC:8693
Ensembl ID ENSG00000120322
Uniprot ID PCDB8_HUMAN
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: -0.728428425; p-value: 0.001874381
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
Protocadherin gamma subfamily B, 1 (PCDHGB1) [1]
HGNC ID HGNC:8708
Ensembl ID ENSG00000254221
Uniprot ID PCDGD_HUMAN
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: -0.721259825; p-value: 0.00633808
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
Click to Download All Target Gene of This Genetic Class
Readthrough
In total 2 target gene(s)
CRYZL2P-SEC16B readthrough (CRYZL2P-SEC16B) [1]
HGNC ID HGNC:53757
Ensembl ID ENSG00000254154
Method RNA-seq GSE121949
Condition knock down
Evidence logFC: 0.836372464; p-value: 0.003382732
Cell Line HepG2 Hepatocellular carcinoma Homo sapiens CVCL_0027
Leucine rich transmembrane and O-methyltransferase domain containing (LRTOMT) [2]
HGNC ID HGNC:25033
Ensembl ID ENSG00000284922
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 2.425834497; p-value: 0.032845157
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
Click to Download All Target Gene of This Genetic Class
Unknown
In total 2 target gene(s)
Chromosome 1 putative open reading frame 220 (C1orf220) [2]
HGNC ID HGNC:33805
Ensembl ID ENSG00000213057
Uniprot ID CA220_HUMAN
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: -1.771075916; p-value: 0.00614083
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
Chromosome 10 putative open reading frame 55 (C10orf55) [2]
HGNC ID HGNC:31008
Ensembl ID ENSG00000222047
Uniprot ID CJ055_HUMAN
Method RNA-seq GSE81164
Condition knock down
Evidence logFC: 1.902074656; p-value: 0.024477019
Cell Line MDA-MB-231 Breast cancer Homo sapiens CVCL_0062
Click to Download All Target Gene of This Genetic Class
References
Ref 1 Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13.
Ref 2 Cross-talk among writers, readers, and erasers of m(6)A regulates cancer growth and progression. Sci Adv. 2018 Oct 3;4(10):eaar8263. doi: 10.1126/sciadv.aar8263. eCollection 2018 Oct.