m6A-centered Drug Response Information
General Information of the Drug (ID: M6APDG01598)
Name |
Testosterone cypionate
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Synonyms |
Testodrin prolongatum; Testosterone 17beta-cyclopentylpropionate; Testosterone 17beta-cypionate; Testosterone cyclopentanepropionate; Testosterone cyclopentylpropionate; Testosterone cypionate [USP]; Testandrone; Testiculosterone; Testim; Testobase; Testoderm; Testogel; Testopropon; Testosteroid; Testosteron; Testosterona; Testosteronum; Testostosterone; Testoviron; Testoviron Schering; Testoviron T; Testrone; Testryl; Virormone; Virosterone; testosterone; trans-Testosterone; 58-22-0; AndroGel; Androderm; Androlin; Andronaq; Andropatch; Andrusol; Cristerona T; Cristerone T; Homosteron; Homosterone; LibiGel; Malerone; Mertestate; Neotestis; Oreton; Orquisteron; Perandren; Primotest; Primoteston; Relibra; Sustanon; Sustanone; Synandrol F; Teslen; UNII-M0XW1UBI14; depAndro 100; depAndro 200; 58-20-8; Andro-Cyp; Androst-4-en-3-one, 17-(3-cyclopentyl-1-oxopropoxy)-, (17b)-; CHEBI:9463; DEPO; Dep-Test; Depo-Testadiol; Depo-Testosterone; Depotest; Depovirin; Durandro; Jectatest; M0XW1UBI14; Malogen CYP; NSC 9157; Pertestis; T-Ionate-P.A; TESTOSTERONE CYPIONATE
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Status |
Approved
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Structure |
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Formula |
C27H40O3
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InChI |
1S/C27H40O3/c1-26-15-13-20(28)17-19(26)8-9-21-22-10-11-24(27(22,2)16-14-23(21)26)30-25(29)12-7-18-5-3-4-6-18/h17-18,21-24H,3-16H2,1-2H3/t21-,22-,23-,24-,26-,27-/m0/s1
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InChIKey |
HPFVBGJFAYZEBE-ZLQWOROUSA-N
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PubChem CID | |||||
INTEDE Drug ID |
Target Gene(s) and Their Upstream m6A Regulator, Together with the Effect of Target Gene(s) in Drug Response
The target genes involved in drug-target interaction (such as drug-metabolizing enzymes, drug transporters and therapeutic targets) and drug-mediated cell death signaling (including modulating DNA damage and repair capacity, escaping from drug-induced apoptosis, autophagy, cellular metabolic reprogramming, oncogenic bypass signaling, cell microenvironment, cell stemness, etc.) could be regulated by m6A regulator(s) and affected their corresponding drug response. You can browse detailed information on drug-related target gene(s) mediated by m6A regulators.
Aromatase (CYP19A1)
Fat mass and obesity-associated protein (FTO)
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Aromatase (CYP19A1) is a therapeutic target for Testosterone cypionate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Testosterone cypionate through regulating the expression of Aromatase (CYP19A1). | [1], [2] | ||
Cytochrome P450 1B1 (CYP1B1)
Methyltransferase-like 14 (METTL14)
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 1B1 (CYP1B1) is a therapeutic target for Testosterone cypionate. The Methyltransferase-like 14 (METTL14) has potential in affecting the response of Testosterone cypionate through regulating the expression of Cytochrome P450 1B1 (CYP1B1). | [3], [4] | ||
Methyltransferase-like 3 (METTL3)
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 1B1 (CYP1B1) is a therapeutic target for Testosterone cypionate. The Methyltransferase-like 3 (METTL3) has potential in affecting the response of Testosterone cypionate through regulating the expression of Cytochrome P450 1B1 (CYP1B1). | [4], [5] | ||
Cytochrome P450 2C8 (CYP2C8)
Fat mass and obesity-associated protein (FTO)
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Testosterone cypionate. The Fat mass and obesity-associated protein (FTO) has potential in affecting the response of Testosterone cypionate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [6], [7] | ||
Methyltransferase-like 14 (METTL14)
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Testosterone cypionate. The Methyltransferase-like 14 (METTL14) has potential in affecting the response of Testosterone cypionate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [6], [7] | ||
Methyltransferase-like 3 (METTL3)
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Testosterone cypionate. The Methyltransferase-like 3 (METTL3) has potential in affecting the response of Testosterone cypionate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [6], [7] | ||
YTH domain-containing protein 2 (YTHDC2)
In total 1 mechanisms lead to this potential drug response | ||||
Response Summary | Cytochrome P450 2C8 (CYP2C8) is a therapeutic target for Testosterone cypionate. The YTH domain-containing protein 2 (YTHDC2) has potential in affecting the response of Testosterone cypionate through regulating the expression of Cytochrome P450 2C8 (CYP2C8). | [6], [7] | ||
References