m6A-centered Disease Response Information
General Information of the Disease (ID: M6ADIS0063)
| Name |
Trachea cancer
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|---|---|---|---|---|---|
| ICD |
ICD-11: 2C24
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Full List of Target Gene(s) of This m6A-centered Disease Response
Oxidative stress-induced growth inhibitor 1 (OSGIN1)
| In total 1 item(s) under this target gene | ||||
| Experiment 1 Reporting the m6A-centered Disease Response by This Target Gene | [1] | |||
| Response Summary | METTL3 regulates PM 2.5-induced cell injury by targeting Oxidative stress-induced growth inhibitor 1 (OSGIN1) in human airway epithelial cells. | |||
| Responsed Disease | Trachea cancer [ICD-11: 2C24] | |||
| Target Regulator | Methyltransferase-like 3 (METTL3) | WRITER | ||
| Target Regulation | Up regulation | |||
| Cell Process | Cell injury | |||
| Cell apoptosis | ||||
| In-vitro Model | A-549 | Lung adenocarcinoma | Homo sapiens | CVCL_0023 |
| HBE (Human bronchial epithelial cell line) | ||||