General Information of the m6A Target Gene (ID: M6ATAR01748)
Target Name Hexokinase-3 (HK3)
Synonyms
EC 2.7.1.1; Hexokinase type III; HK III; Hexokinase-C
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Gene Name HK3
Chromosomal Location 5q35.2
Family Hexokinase family
Function
Catalyzes the phosphorylation of hexose, such as D-glucose and D-fructose, to hexose 6-phosphate (D-glucose 6-phosphate and D-fructose 6-phosphate, respectively) (PubMed:8717435). Mediates the initial step of glycolysis by catalyzing phosphorylation of D-glucose to D-glucose 6-phosphate (PubMed:8717435).
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Gene ID 3101
Uniprot ID
HXK3_HUMAN
HGNC ID
HGNC:4925
KEGG ID
hsa:3101
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
Non-coding RNA
m6A Regulator: Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05229
Epigenetic Regulator Circ_ZBTB44
Regulated Target Insulin like growth factor 2 mRNA binding protein 3 (IGF2BP3)
Crosstalk relationship ncRNA → m6A
Disease Renal cell carcinoma
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01748)
Hexokinase-3 (HK3)
5-methylcytidine (m5C)
In total 3 m6A sequence/site(s) in this target gene
mod ID: M5CSITE003695 Click to Show/Hide the Full List
mod site chr5:176887069-176887070:- [2]
Sequence ACTTCCAGCAGAAGCAGGGCCTGAGCGGGCAGAGCCTCCCA
Seq Type List Bisulfite-seq
Transcript ID List ENST00000509717.5; ENST00000292432.10; ENST00000506834.5
External Link RMBase: m5C_site_36441
mod ID: M5CSITE003696 Click to Show/Hide the Full List
mod site chr5:176887070-176887071:- [2]
Sequence GACTTCCAGCAGAAGCAGGGCCTGAGCGGGCAGAGCCTCCC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000506834.5; ENST00000292432.10; ENST00000509717.5
External Link RMBase: m5C_site_36442
mod ID: M5CSITE003697 Click to Show/Hide the Full List
mod site chr5:176887075-176887076:- [2]
Sequence TCGTGGACTTCCAGCAGAAGCAGGGCCTGAGCGGGCAGAGC
Seq Type List Bisulfite-seq
Transcript ID List ENST00000509717.5; ENST00000292432.10; ENST00000506834.5
External Link RMBase: m5C_site_36444
N6-methyladenosine (m6A)
In total 1 m6A sequence/site(s) in this target gene
mod ID: M6ASITE072874 Click to Show/Hide the Full List
mod site chr5:176881367-176881368:- [3]
Sequence GGTGGAGAAGATCCGGGAGAACCGGGGCCTGGAAGAGCTGG
Motif Score 2.930744048
Cell/Tissue List peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000506834.5; ENST00000292432.10; ENST00000514666.1
External Link RMBase: m6A_site_699365