General Information of the m6A Target Gene (ID: M6ATAR01735)
Target Name Hydroxymethylglutaryl-CoA synthase, mitochondrial (HMGCS2)
Synonyms
HMG-CoA synthase; EC 2.3.3.10; 3-hydroxy-3-methylglutaryl coenzyme A synthase
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Gene Name HMGCS2
Chromosomal Location 1p12
Family Thiolase-like superfamily, HMG-CoA synthase family
Function
Catalyzes the first irreversible step in ketogenesis, condensing acetyl-CoA to acetoacetyl-CoA to form HMG-CoA, which is converted by HMG-CoA reductase (HMGCR) into mevalonate.
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Gene ID 3158
Uniprot ID
HMCS2_HUMAN
HGNC ID
HGNC:5008
KEGG ID
hsa:3158
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
Non-coding RNA
m6A Regulator: Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1)
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05192
Epigenetic Regulator LOC101928222
Regulated Target Insulin like growth factor 2 mRNA binding protein 1 (IGF2BP1)
Crosstalk relationship ncRNA → m6A
Disease Colorectal cancer
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01735)
Hydroxymethylglutaryl-CoA synthase, mitochondrial (HMGCS2)
N6-methyladenosine (m6A)
In total 10 m6A sequence/site(s) in this target gene
mod ID: M6ASITE046097 Click to Show/Hide the Full List
mod site chr1:119748281-119748282:- [2]
Sequence GAGGGCTGGGTCCTTGCCTCACAGGCTGCCTCTGTCCCCTT
Motif Score 2.047297619
Cell/Tissue List kidney
Seq Type List m6A-REF-seq
Transcript ID List ENST00000369406.7
External Link RMBase: m6A_site_48274
mod ID: M6ASITE046098 Click to Show/Hide the Full List
mod site chr1:119759961-119759962:- [3]
Sequence TGCCATGGTGGTCTGTGGAGACATTGCCGTCTATCCCAGTG
Motif Score 2.897386905
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000369406.7; ENST00000476640.1; ENST00000544913.2
External Link RMBase: m6A_site_48275
mod ID: M6ASITE046099 Click to Show/Hide the Full List
mod site chr1:119764289-119764290:- [3]
Sequence GTCAAAACAGTGCTCATGGAACTCTTCCAGGATTCAGGCAA
Motif Score 3.373380952
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000544913.2; ENST00000476640.1; ENST00000369406.7
External Link RMBase: m6A_site_48276
mod ID: M6ASITE046100 Click to Show/Hide the Full List
mod site chr1:119764303-119764304:- [3]
Sequence ACAAGTCCAAAGCTGTCAAAACAGTGCTCATGGAACTCTTC
Motif Score 2.20572619
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000369406.7; ENST00000476640.1; ENST00000544913.2
External Link RMBase: m6A_site_48277
mod ID: M6ASITE046101 Click to Show/Hide the Full List
mod site chr1:119764333-119764334:- [3]
Sequence GGCTGGAAGTAGGCACTGAGACCATCATTGACAAGTCCAAA
Motif Score 2.876744048
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000369406.7; ENST00000544913.2; ENST00000476640.1
External Link RMBase: m6A_site_48278
mod ID: M6ASITE046102 Click to Show/Hide the Full List
mod site chr1:119764365-119764366:- [3]
Sequence GCGCATACAGCTCCCATGGGACTCTGTGGGCAGGCTGGAAG
Motif Score 4.065041667
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000369406.7; ENST00000476640.1; ENST00000544913.2
External Link RMBase: m6A_site_48279
mod ID: M6ASITE046103 Click to Show/Hide the Full List
mod site chr1:119764428-119764429:- [2]
Sequence CTTCTGCTCAGTCCAAGAGGACATCAACTCCCTGTGCCTGA
Motif Score 3.643047619
Cell/Tissue List kidney; liver; iSLK
Seq Type List m6A-REF-seq; MeRIP-seq
Transcript ID List ENST00000476640.1; ENST00000369406.7; ENST00000544913.2
External Link RMBase: m6A_site_48280
mod ID: M6ASITE046104 Click to Show/Hide the Full List
mod site chr1:119764459-119764460:- [3]
Sequence ATACAGTGGGCTTGGGCCAGACCCGTATGGGCTTCTGCTCA
Motif Score 2.876744048
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000476640.1; ENST00000369406.7; ENST00000544913.2
External Link RMBase: m6A_site_48281
mod ID: M6ASITE046105 Click to Show/Hide the Full List
mod site chr1:119764591-119764592:- [2]
Sequence CTGCTGTCCCCCTGGCCAAAACAGATACTTGGCCAAAGGAC
Motif Score 2.20572619
Cell/Tissue List kidney; liver; iSLK
Seq Type List m6A-REF-seq; MeRIP-seq
Transcript ID List ENST00000544913.2; ENST00000476640.1; ENST00000369406.7
External Link RMBase: m6A_site_48282
mod ID: M6ASITE046106 Click to Show/Hide the Full List
mod site chr1:119768783-119768784:- [3]
Sequence TGACAAGAGCGGTGCAGGAAACCTCCCTCACACCTGCTCGC
Motif Score 2.185083333
Cell/Tissue List iSLK
Seq Type List MeRIP-seq
Transcript ID List ENST00000544913.2; ENST00000369406.7
External Link RMBase: m6A_site_48283