m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01710)

Target Name	Elongation factor Ts, mitochondrial (TSFM)
Synonyms	EF-Ts; EF-TsMt Click to Show/Hide
Gene Name	TSFM
Chromosomal Location	12q14.1
Family	EF-Ts family
Function	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Click to Show/Hide
Gene ID	10102
Uniprot ID	EFTS_HUMAN
HGNC ID	HGNC:12367
KEGG ID	hsa:10102

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Non-coding RNA

m6A Regulator: YTH domain-containing protein 1 (YTHDC1)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05106		Crosstalk Info
Epigenetic Regulator	piR-26441
Regulated Target	YTH N6-methyladenosine RNA binding protein C1 (YTHDC1)
Crosstalk relationship	ncRNA → m6A
Disease	Ovarian cancer	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01710)

Elongation factor Ts, mitochondrial (TSFM)

Adenosine-to-Inosine editing (A-to-I)

In total 1 m6A sequence/site(s) in this target gene
mod ID: A2ISITE005630		Click to Show/Hide the Full List
mod site	chr12:57784990-57784991:+		[2]
Sequence	GGCTGGACTGCAGTGGCACAATCTTGGCTCACTGCAAGCTC
Transcript ID List	ENST00000546504.1; ENST00000553083.1; ENST00000434359.5; ENST00000651899.1; ENST00000417094.5; ENST00000323833.12; ENST00000457189.1; ENST00000652027.1; ENST00000540550.6; ENST00000543727.5; ENST00000548851.5; ENST00000471530.5; ENST00000550559.5; ENST00000497617.1; ENST00000454289.8; ENST00000651066.1; ENST00000651284.1
External Link	RMBase: RNA-editing_site_29500

N6-methyladenosine (m6A)

In total 37 m6A sequence/site(s) in this target gene
mod ID: M6ASITE013717		Click to Show/Hide the Full List
mod site	chr12:57782843-57782844:+		[3]
Sequence	GCGTGTTTCTGGTCGCGCGGACCGGGAGCTACCCGGTGAGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000651066.1; ENST00000323833.12; ENST00000550559.5; ENST00000454289.8; ENST00000471530.5; ENST00000417094.5; ENST00000457189.1; ENST00000548851.5; ENST00000652027.1; ENST00000434359.5; ENST00000543727.5; ENST00000546504.1; ENST00000553083.1; ENST00000651899.1; ENST00000651284.1; ENST00000540550.6
External Link	RMBase: m6A_site_195904
mod ID: M6ASITE013718		Click to Show/Hide the Full List
mod site	chr12:57783146-57783147:+		[4]
Sequence	TCAGTCGCCCCAGCCAAGGCACACATTTTATGCTGGGCCCC
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000553083.1; ENST00000548851.5; ENST00000652027.1; ENST00000454289.8; ENST00000540550.6; ENST00000323833.12; ENST00000651284.1; ENST00000651899.1; ENST00000550559.5; ENST00000434359.5; ENST00000457189.1; ENST00000471530.5; ENST00000497617.1; ENST00000543727.5; ENST00000546504.1; ENST00000417094.5; ENST00000651066.1
External Link	RMBase: m6A_site_195905
mod ID: M6ASITE013719		Click to Show/Hide the Full List
mod site	chr12:57783220-57783221:+		[3]
Sequence	TCATGAAGCTGCGGCGGAAAACAGGCTACTCCTTTGTAAAT
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000497617.1; ENST00000471530.5; ENST00000652027.1; ENST00000434359.5; ENST00000457189.1; ENST00000323833.12; ENST00000651899.1; ENST00000550559.5; ENST00000543727.5; ENST00000540550.6; ENST00000454289.8; ENST00000651066.1; ENST00000553083.1; ENST00000548851.5; ENST00000651284.1; ENST00000546504.1; ENST00000417094.5
External Link	RMBase: m6A_site_195906
mod ID: M6ASITE013720		Click to Show/Hide the Full List
mod site	chr12:57783259-57783260:+		[3]
Sequence	ATTGCAAGAAAGCTCTGGAGACTTGTGGCGGGGACCTCAAA
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000434359.5; ENST00000417094.5; ENST00000651899.1; ENST00000497617.1; ENST00000471530.5; ENST00000651284.1; ENST00000457189.1; ENST00000550559.5; ENST00000454289.8; ENST00000543727.5; ENST00000553083.1; ENST00000651066.1; ENST00000540550.6; ENST00000546504.1; ENST00000652027.1; ENST00000323833.12; ENST00000548851.5
External Link	RMBase: m6A_site_195907
mod ID: M6ASITE013721		Click to Show/Hide the Full List
mod site	chr12:57783272-57783273:+		[3]
Sequence	TCTGGAGACTTGTGGCGGGGACCTCAAACAGGTGTGTGTGT
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000434359.5; ENST00000553083.1; ENST00000651284.1; ENST00000543727.5; ENST00000323833.12; ENST00000471530.5; ENST00000548851.5; ENST00000546504.1; ENST00000550559.5; ENST00000540550.6; ENST00000454289.8; ENST00000457189.1; ENST00000651066.1; ENST00000652027.1; ENST00000417094.5; ENST00000497617.1; ENST00000651899.1
External Link	RMBase: m6A_site_195908
mod ID: M6ASITE013722		Click to Show/Hide the Full List
mod site	chr12:57783279-57783280:+		[3]
Sequence	ACTTGTGGCGGGGACCTCAAACAGGTGTGTGTGTGGAGGGG
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000417094.5; ENST00000553083.1; ENST00000651066.1; ENST00000548851.5; ENST00000652027.1; ENST00000323833.12; ENST00000550559.5; ENST00000543727.5; ENST00000651284.1; ENST00000497617.1; ENST00000457189.1; ENST00000546504.1; ENST00000651899.1; ENST00000434359.5; ENST00000471530.5; ENST00000454289.8; ENST00000540550.6
External Link	RMBase: m6A_site_195909
mod ID: M6ASITE013723		Click to Show/Hide the Full List
mod site	chr12:57784118-57784119:+		[5]
Sequence	CAGCTGCTCCTAGGCTACAAACCGTTACAAAATGTTACTGG
Motif Score	2.185083333
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000543727.5; ENST00000651284.1; ENST00000553083.1; ENST00000546504.1; ENST00000323833.12; ENST00000497617.1; ENST00000651066.1; ENST00000548851.5; ENST00000651899.1; ENST00000454289.8; ENST00000457189.1; ENST00000652027.1; ENST00000434359.5; ENST00000540550.6; ENST00000550559.5; ENST00000471530.5; ENST00000417094.5
External Link	RMBase: m6A_site_195910
mod ID: M6ASITE013724		Click to Show/Hide the Full List
mod site	chr12:57784139-57784140:+		[6]
Sequence	CCGTTACAAAATGTTACTGGACTGAATACTGTAGGCAGTTG
Motif Score	4.065041667
Cell/Tissue List	HepG2; HeLa; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000323833.12; ENST00000546504.1; ENST00000471530.5; ENST00000550559.5; ENST00000651284.1; ENST00000540550.6; ENST00000543727.5; ENST00000497617.1; ENST00000651066.1; ENST00000553083.1; ENST00000417094.5; ENST00000651899.1; ENST00000434359.5; ENST00000548851.5; ENST00000652027.1; ENST00000457189.1; ENST00000454289.8
External Link	RMBase: m6A_site_195911
mod ID: M6ASITE013725		Click to Show/Hide the Full List
mod site	chr12:57786178-57786179:+		[4]
Sequence	ACAGGCAGAGATCTGGCTCCACAAGGAGGCCCAGAAGGAGG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000454289.8; ENST00000548851.5; ENST00000417094.5; ENST00000457189.1; ENST00000651899.1; ENST00000550559.5; ENST00000652027.1; ENST00000497617.1; ENST00000651284.1; ENST00000434359.5; ENST00000323833.12; ENST00000546504.1; ENST00000540550.6; ENST00000651066.1; ENST00000553083.1; ENST00000543727.5; ENST00000471530.5
External Link	RMBase: m6A_site_195912
mod ID: M6ASITE013726		Click to Show/Hide the Full List
mod site	chr12:57786234-57786235:+		[6]
Sequence	CCAAGCTCCAAGGGAGGAAGACCAAAGAAGGCCTGATTGGG
Motif Score	2.876744048
Cell/Tissue List	HepG2; HeLa; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000553083.1; ENST00000651284.1; ENST00000540550.6; ENST00000651066.1; ENST00000434359.5; ENST00000548851.5; ENST00000497617.1; ENST00000651899.1; ENST00000454289.8; ENST00000323833.12; ENST00000652027.1; ENST00000457189.1; ENST00000550559.5; ENST00000543727.5; ENST00000471530.5; ENST00000546504.1
External Link	RMBase: m6A_site_195913
mod ID: M6ASITE013727		Click to Show/Hide the Full List
mod site	chr12:57786271-57786272:+		[6]
Sequence	TGGGCTGTTGCAGGAAGGAAACACAACTGTATTAGTAGAGG
Motif Score	2.20572619
Cell/Tissue List	HepG2; HeLa; hESC-HEK293T; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000457189.1; ENST00000540550.6; ENST00000454289.8; ENST00000550559.5; ENST00000652027.1; ENST00000651284.1; ENST00000651066.1; ENST00000651899.1; ENST00000434359.5; ENST00000323833.12; ENST00000497617.1; ENST00000471530.5; ENST00000543727.5; ENST00000548851.5
External Link	RMBase: m6A_site_195914
mod ID: M6ASITE013728		Click to Show/Hide the Full List
mod site	chr12:57787043-57787044:+		[6]
Sequence	CAATTTGTTCCCACAGGTAAACTGTGAGACAGATTTTGTTT
Motif Score	2.627720238
Cell/Tissue List	HepG2; HeLa; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000457189.1; ENST00000652027.1; ENST00000471530.5; ENST00000651284.1; ENST00000543727.5; ENST00000651899.1; ENST00000548851.5; ENST00000540550.6; ENST00000497617.1; ENST00000323833.12; ENST00000454289.8; ENST00000434359.5; ENST00000550559.5; ENST00000651066.1
External Link	RMBase: m6A_site_195915
mod ID: M6ASITE013729		Click to Show/Hide the Full List
mod site	chr12:57787051-57787052:+		[6]
Sequence	TCCCACAGGTAAACTGTGAGACAGATTTTGTTTCTAGAAAT
Motif Score	2.897386905
Cell/Tissue List	HepG2; HeLa; HEK293T; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; NB4; MM6
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000651066.1; ENST00000550559.5; ENST00000497617.1; ENST00000651284.1; ENST00000323833.12; ENST00000543727.5; ENST00000434359.5; ENST00000454289.8; ENST00000652027.1; ENST00000457189.1; ENST00000540550.6; ENST00000651899.1; ENST00000548851.5
External Link	RMBase: m6A_site_195916
mod ID: M6ASITE013730		Click to Show/Hide the Full List
mod site	chr12:57787111-57787112:+		[7]
Sequence	TCCAGCAAGTAGCCCTTGGAACCATGATGCATTGTCAGACC
Motif Score	2.930744048
Cell/Tissue List	peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000543727.5; ENST00000540550.6; ENST00000323833.12; ENST00000651066.1; ENST00000434359.5; ENST00000550559.5; ENST00000651899.1; ENST00000652027.1; ENST00000548851.5; ENST00000497617.1; ENST00000651284.1; ENST00000454289.8; ENST00000457189.1
External Link	RMBase: m6A_site_195917
mod ID: M6ASITE013731		Click to Show/Hide the Full List
mod site	chr12:57796191-57796192:+		[4]
Sequence	AATAGGAAAACTGGGAGAAAACATGATTCTTAAACGAGCTG
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000543727.5; ENST00000323833.12; ENST00000651066.1; ENST00000540550.6; ENST00000548851.5; ENST00000651899.1; ENST00000454289.8; ENST00000457189.1; ENST00000651284.1; ENST00000652027.1; ENST00000497617.1; ENST00000550559.5
External Link	RMBase: m6A_site_195918
mod ID: M6ASITE013732		Click to Show/Hide the Full List
mod site	chr12:57796284-57796285:+		[8]
Sequence	AATGCAGAGTCCCTCACTTCACAAGCTGGTGCTGGGGAAGT
Motif Score	2.047297619
Cell/Tissue List	brain; liver; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000497617.1; ENST00000550559.5; ENST00000548851.5; ENST00000651066.1; ENST00000651284.1; ENST00000543727.5; ENST00000454289.8; ENST00000651899.1; ENST00000540550.6; ENST00000652027.1; ENST00000323833.12
External Link	RMBase: m6A_site_195919
mod ID: M6ASITE013733		Click to Show/Hide the Full List
mod site	chr12:57796336-57796337:+		[3]
Sequence	GTCATCTGTGAGACGTCTGAACAGAAAACAAACCTTGAAGA
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; HepG2; U2OS; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651066.1; ENST00000540550.6; ENST00000497617.1; ENST00000652027.1; ENST00000548851.5; ENST00000651284.1; ENST00000543727.5; ENST00000651899.1; ENST00000454289.8; ENST00000550559.5; ENST00000323833.12
External Link	RMBase: m6A_site_195920
mod ID: M6ASITE013734		Click to Show/Hide the Full List
mod site	chr12:57796343-57796344:+		[3]
Sequence	GTGAGACGTCTGAACAGAAAACAAACCTTGAAGACGTTGGC
Motif Score	2.20572619
Cell/Tissue List	HeLa; CD34; HEK293T; HepG2; U2OS; A549; peripheral-blood; HEK293A-TOA; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000543727.5; ENST00000323833.12; ENST00000497617.1; ENST00000651899.1; ENST00000550559.5; ENST00000651066.1; ENST00000651284.1; ENST00000652027.1; ENST00000548851.5; ENST00000540550.6; ENST00000454289.8
External Link	RMBase: m6A_site_195921
mod ID: M6ASITE013735		Click to Show/Hide the Full List
mod site	chr12:57796419-57796420:+		[9]
Sequence	CCTCTCTGTTGGCTCCCTGGACGATGAGCCTGGGGGAGAGG
Motif Score	3.616982143
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000543727.5; ENST00000548851.5; ENST00000651899.1; ENST00000651284.1; ENST00000652027.1; ENST00000651066.1; ENST00000323833.12; ENST00000540550.6; ENST00000550559.5; ENST00000454289.8
External Link	RMBase: m6A_site_195922
mod ID: M6ASITE013736		Click to Show/Hide the Full List
mod site	chr12:57796445-57796446:+		[3]
Sequence	AGCCTGGGGGAGAGGCAGAGACTAAGATGCTGTCCCAGCCG
Motif Score	3.319380952
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; TREX; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP; miCLIP
Transcript ID List	ENST00000323833.12; ENST00000652027.1; ENST00000651899.1; ENST00000651284.1; ENST00000550559.5; ENST00000543727.5; ENST00000651066.1; ENST00000548851.5; ENST00000454289.8; ENST00000540550.6
External Link	RMBase: m6A_site_195923
mod ID: M6ASITE013737		Click to Show/Hide the Full List
mod site	chr12:57796530-57796531:+		[3]
Sequence	TCAGGGGGTGTCGGTAGTAGACTTTGTGCGGTTTGAATGTG
Motif Score	3.319380952
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; BGC823; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000652027.1; ENST00000548851.5; ENST00000454289.8; ENST00000543727.5; ENST00000651066.1; ENST00000323833.12; ENST00000651899.1; ENST00000550559.5; ENST00000540550.6; ENST00000651284.1
External Link	RMBase: m6A_site_195924
mod ID: M6ASITE013738		Click to Show/Hide the Full List
mod site	chr12:57796574-57796575:+		[3]
Sequence	AAGGTGAAGAGGCAGCAGAAACTGAATAGGTTCCAGAGACT
Motif Score	2.627720238
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; BGC823; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; CD8T; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP; miCLIP
Transcript ID List	ENST00000323833.12; ENST00000548851.5; ENST00000540550.6; ENST00000652027.1; ENST00000651899.1; ENST00000550559.5; ENST00000651284.1; ENST00000651066.1; ENST00000543727.5; ENST00000454289.8
External Link	RMBase: m6A_site_195925
mod ID: M6ASITE013739		Click to Show/Hide the Full List
mod site	chr12:57796592-57796593:+		[3]
Sequence	AAACTGAATAGGTTCCAGAGACTTTTGGCCCAGGAGGAATA
Motif Score	3.319380952
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; BGC823; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000454289.8; ENST00000323833.12; ENST00000652027.1; ENST00000651284.1; ENST00000651899.1; ENST00000543727.5; ENST00000550559.5; ENST00000651066.1; ENST00000548851.5; ENST00000540550.6
External Link	RMBase: m6A_site_195926
mod ID: M6ASITE013740		Click to Show/Hide the Full List
mod site	chr12:57796630-57796631:+		[3]
Sequence	ATATTTACTTTTAGCTCTGGACATCATTACAAAAAGGAATA
Motif Score	3.643047619
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; kidney; liver; A549; hESC-HEK293T; BGC823; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-REF-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000651284.1; ENST00000454289.8; ENST00000548851.5; ENST00000651066.1; ENST00000540550.6; ENST00000323833.12; ENST00000651899.1; ENST00000550559.5; ENST00000543727.5; ENST00000652027.1
External Link	RMBase: m6A_site_195927
mod ID: M6ASITE013741		Click to Show/Hide the Full List
mod site	chr12:57796638-57796639:+		[10]
Sequence	TTTTAGCTCTGGACATCATTACAAAAAGGAATATTTCCCAA
Motif Score	2.07285119
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000652027.1; ENST00000543727.5; ENST00000323833.12; ENST00000651066.1; ENST00000550559.5; ENST00000540550.6; ENST00000548851.5; ENST00000651284.1; ENST00000651899.1; ENST00000454289.8
External Link	RMBase: m6A_site_195928
mod ID: M6ASITE013742		Click to Show/Hide the Full List
mod site	chr12:57796659-57796660:+		[3]
Sequence	CAAAAAGGAATATTTCCCAAACCTCTTCAGACCGAGAATGC
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; BGC823; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000323833.12; ENST00000651899.1; ENST00000454289.8; ENST00000651066.1; ENST00000652027.1; ENST00000540550.6; ENST00000543727.5; ENST00000548851.5; ENST00000550559.5; ENST00000651284.1
External Link	RMBase: m6A_site_195929
mod ID: M6ASITE013743		Click to Show/Hide the Full List
mod site	chr12:57796669-57796670:+		[3]
Sequence	TATTTCCCAAACCTCTTCAGACCGAGAATGCATGGGTAAAA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; BGC823; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000651066.1; ENST00000652027.1; ENST00000651284.1; ENST00000548851.5; ENST00000540550.6; ENST00000550559.5; ENST00000454289.8; ENST00000543727.5; ENST00000651899.1; ENST00000323833.12
External Link	RMBase: m6A_site_195930
mod ID: M6ASITE013744		Click to Show/Hide the Full List
mod site	chr12:57796770-57796771:+		[3]
Sequence	CTTTTCTGTGCCTTTCAAAAACAACAGGTGGGCCTTATTGA
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; Huh7; iSLK; MSC; TREX; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000540550.6; ENST00000548851.5; ENST00000454289.8; ENST00000652027.1; ENST00000543727.5; ENST00000550559.5; ENST00000651066.1; ENST00000651284.1
External Link	RMBase: m6A_site_195931
mod ID: M6ASITE013745		Click to Show/Hide the Full List
mod site	chr12:57796810-57796811:+		[11]
Sequence	ACGTGATAGTGTCGTGGAGAACAGGCATCAACAATACTGCT
Motif Score	2.951386905
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000543727.5; ENST00000548851.5; ENST00000651284.1; ENST00000550559.5; ENST00000651066.1; ENST00000454289.8; ENST00000540550.6; ENST00000652027.1
External Link	RMBase: m6A_site_195932
mod ID: M6ASITE013746		Click to Show/Hide the Full List
mod site	chr12:57796912-57796913:+		[3]
Sequence	TACACCTTTTATGACATAGAACTCTTTTGTTCTGTTTTTGC
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000550559.5; ENST00000652027.1; ENST00000548851.5; ENST00000651284.1; ENST00000540550.6; ENST00000454289.8; ENST00000543727.5; ENST00000651066.1
External Link	RMBase: m6A_site_195933
mod ID: M6ASITE013747		Click to Show/Hide the Full List
mod site	chr12:57796948-57796949:+		[3]
Sequence	TTTGCTTTGCGACACTGTGAACCGTGCTTCTGCCTCGGAAC
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000550559.5; ENST00000651284.1; ENST00000454289.8; ENST00000540550.6; ENST00000652027.1; ENST00000651066.1; ENST00000543727.5; ENST00000548851.5
External Link	RMBase: m6A_site_195934
mod ID: M6ASITE013748		Click to Show/Hide the Full List
mod site	chr12:57796967-57796968:+		[3]
Sequence	AACCGTGCTTCTGCCTCGGAACCTCCCTAGTTATATTACTT
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000651066.1; ENST00000652027.1; ENST00000454289.8; ENST00000550559.5; ENST00000540550.6; ENST00000543727.5; ENST00000548851.5; ENST00000651284.1
External Link	RMBase: m6A_site_195935
mod ID: M6ASITE013749		Click to Show/Hide the Full List
mod site	chr12:57797221-57797222:+		[4]
Sequence	CAGCTGTAAGGCAGATTTTGACATTCTTGTGCCAGAAACAG
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000652027.1; ENST00000454289.8; ENST00000651066.1; ENST00000550559.5; ENST00000548851.5; ENST00000651284.1; ENST00000543727.5; ENST00000540550.6
External Link	RMBase: m6A_site_195936
mod ID: M6ASITE013750		Click to Show/Hide the Full List
mod site	chr12:57808036-57808037:+		[12]
Sequence	TGCCTTTCACTACCCTGAAAACTCTACAGACTCACAAGACT
Motif Score	2.627720238
Cell/Tissue List	HEK293T; HEK293A-TOA
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000548851.5
External Link	RMBase: m6A_site_195939
mod ID: M6ASITE013751		Click to Show/Hide the Full List
mod site	chr12:57808045-57808046:+		[13]
Sequence	CTACCCTGAAAACTCTACAGACTCACAAGACTCTTAAAGAA
Motif Score	3.319380952
Cell/Tissue List	HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000548851.5
External Link	RMBase: m6A_site_195940
mod ID: M6ASITE013752		Click to Show/Hide the Full List
mod site	chr12:57808054-57808055:+		[13]
Sequence	AAACTCTACAGACTCACAAGACTCTTAAAGAAGACTCCTGA
Motif Score	3.319380952
Cell/Tissue List	HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000548851.5
External Link	RMBase: m6A_site_195941
mod ID: M6ASITE013753		Click to Show/Hide the Full List
mod site	chr12:57808067-57808068:+		[13]
Sequence	TCACAAGACTCTTAAAGAAGACTCCTGAGGTGCCGGAGGGG
Motif Score	3.319380952
Cell/Tissue List	HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000548851.5
External Link	RMBase: m6A_site_195942

Pseudouridine (Pseudo)

In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000021		Click to Show/Hide the Full List
mod site	chr12:57782802-57782803:+		[14]
Sequence	GTTTATCGCGGCTAGAGAGATGTCGCTGCTGCGGTCGCTGC
Transcript ID List	ENST00000434359.5; ENST00000651284.1; ENST00000553083.1; ENST00000651066.1; ENST00000471530.5; ENST00000550559.5; ENST00000543727.5; ENST00000651899.1; ENST00000652027.1; ENST00000548851.5; ENST00000417094.5; ENST00000540550.6; ENST00000323833.12; ENST00000454289.8; ENST00000546504.1
External Link	RMBase: Pseudo_site_1162

Ref 1	ClinicalTrials.gov (NCT03638167) EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 4	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 5	m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27.
Ref 6	Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13.
Ref 7	R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m(6)A/MYC/CEBPA Signaling. Cell. 2018 Jan 11;172(1-2):90-105.e23. doi: 10.1016/j.cell.2017.11.031. Epub 2017 Dec 14.
Ref 8	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 9	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 10	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 11	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 12	Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons. Cell. 2012 Jun 22;149(7):1635-46. doi: 10.1016/j.cell.2012.05.003. Epub 2012 May 17.
Ref 13	The U6 snRNA m(6)A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. Cell. 2017 May 18;169(5):824-835.e14. doi: 10.1016/j.cell.2017.05.003.
Ref 14	Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome. Nat Chem Biol. 2015 Aug;11(8):592-7. doi: 10.1038/nchembio.1836. Epub 2015 Jun 15.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

Visitor Map