m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01709)

Target Name	Nucleosome assembly protein 1-like 2 (NAP1L2)
Synonyms	Brain-specific protein, X-linked Click to Show/Hide
Gene Name	NAP1L2
Chromosomal Location	Xq13.2
Family	Nucleosome assembly protein (NAP) family
Function	Acidic protein which may be involved in interactions with other proteins or DNA. Click to Show/Hide
Gene ID	4674
Uniprot ID	NP1L2_HUMAN
HGNC ID	HGNC:7638
KEGG ID	hsa:4674

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Non-coding RNA

m6A Regulator: Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05102		Crosstalk Info
Epigenetic Regulator	Nucleosome assembly protein 1 like 6, pseudogene (NAP1L6P)
Regulated Target	Heterogeneous nuclear ribonucleoprotein C (HNRNPC)
Crosstalk relationship	ncRNA → m6A
Disease	Prostate cancer	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01709)

Nucleosome assembly protein 1-like 2 (NAP1L2)

N6-methyladenosine (m6A)

In total 29 m6A sequence/site(s) in this target gene
mod ID: M6ASITE092116		Click to Show/Hide the Full List
mod site	chrX:73212529-73212530:-		[2]
Sequence	TAACTGTGATAAATAATGAAACTTAGTTATATTGAGGTTAT
Motif Score	2.627720238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864341
mod ID: M6ASITE092117		Click to Show/Hide the Full List
mod site	chrX:73213009-73213010:-		[3]
Sequence	TTCTTGTAGTGTTAGTTAAAACATATGTTTCAAAAATATAA
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864342
mod ID: M6ASITE092118		Click to Show/Hide the Full List
mod site	chrX:73213143-73213144:-
Sequence	AGTTAAAGCTTGTTGCAAAAACCTTGAGGCATTAGTAGAAG
Motif Score	2.185083333
Cell/Tissue List	HEK293T
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864343
mod ID: M6ASITE092119		Click to Show/Hide the Full List
mod site	chrX:73213311-73213312:-		[3]
Sequence	TGATGATTTTTTACTTGGTCACAATTTACGTACTTACATAA
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864344
mod ID: M6ASITE092120		Click to Show/Hide the Full List
mod site	chrX:73213414-73213415:-		[4]
Sequence	GGATCTGGGGAACAATCCGAACTGTAACTGAAGATTTTCCC
Motif Score	3.373380952
Cell/Tissue List	HEK293T; U2OS; hESCs; GM12878
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864345
mod ID: M6ASITE092121		Click to Show/Hide the Full List
mod site	chrX:73213423-73213424:-		[5]
Sequence	AGAAACATCGGATCTGGGGAACAATCCGAACTGTAACTGAA
Motif Score	2.951386905
Cell/Tissue List	HEK293T; kidney; hESC-HEK293T; U2OS; hESCs; GM12878; A549
Seq Type List	MeRIP-seq; m6A-REF-seq; MAZTER-seq; m6A-seq; m6A-CLIP/IP
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864346
mod ID: M6ASITE092122		Click to Show/Hide the Full List
mod site	chrX:73213439-73213440:-		[4]
Sequence	ACCATCAAGAAGAAACAGAAACATCGGATCTGGGGAACAAT
Motif Score	2.20572619
Cell/Tissue List	HEK293T; U2OS; hESCs; GM12878
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864347
mod ID: M6ASITE092123		Click to Show/Hide the Full List
mod site	chrX:73213445-73213446:-		[4]
Sequence	TTGAAAACCATCAAGAAGAAACAGAAACATCGGATCTGGGG
Motif Score	2.20572619
Cell/Tissue List	HEK293T; U2OS; hESCs; GM12878
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864348
mod ID: M6ASITE092124		Click to Show/Hide the Full List
mod site	chrX:73213459-73213460:-		[4]
Sequence	GAAAGAATGTCACTTTGAAAACCATCAAGAAGAAACAGAAA
Motif Score	2.185083333
Cell/Tissue List	HEK293T; U2OS; hESCs; GM12878
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864349
mod ID: M6ASITE092125		Click to Show/Hide the Full List
mod site	chrX:73213507-73213508:-		[5]
Sequence	GAACTGCGATTGAGTATTCCACAGGCTGTGAGATAGATTGG
Motif Score	2.053113095
Cell/Tissue List	brain
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864350
mod ID: M6ASITE092126		Click to Show/Hide the Full List
mod site	chrX:73213525-73213526:-		[6]
Sequence	ATCCCCATCCCTATAGGGGAACTGCGATTGAGTATTCCACA
Motif Score	3.373380952
Cell/Tissue List	HEK293T; A549; U2OS; hNPCs; hESCs
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864351
mod ID: M6ASITE092127		Click to Show/Hide the Full List
mod site	chrX:73213579-73213580:-		[4]
Sequence	AAAATGAGTTGTTGACAAAGACCTATGTGCTGAAGTCAAAG
Motif Score	2.876744048
Cell/Tissue List	HEK293T; U2OS; hNPCs; hESCs; GM12878
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864352
mod ID: M6ASITE092128		Click to Show/Hide the Full List
mod site	chrX:73213585-73213586:-		[3]
Sequence	ATTTCAAAAATGAGTTGTTGACAAAGACCTATGTGCTGAAG
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864353
mod ID: M6ASITE092129		Click to Show/Hide the Full List
mod site	chrX:73213616-73213617:-		[4]
Sequence	ACACTAGAATTTCACTTCAAACCCAATGAATATTTCAAAAA
Motif Score	2.185083333
Cell/Tissue List	HEK293T; U2OS; hNPCs; hESCs; A549; GM12878
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864354
mod ID: M6ASITE092130		Click to Show/Hide the Full List
mod site	chrX:73213824-73213825:-		[3]
Sequence	GGAGGAGGAGGAGGAGGACGACATTGAGGCTACTGGAGAAG
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864355
mod ID: M6ASITE092131		Click to Show/Hide the Full List
mod site	chrX:73213878-73213879:-		[6]
Sequence	TGAGGACGATGGTTATGAGGACTATTATTATGATTATGCTG
Motif Score	4.065041667
Cell/Tissue List	HEK293T; A549; U2OS; H1B; hNPCs; hESCs; fibroblasts; GM12878; CD8T; MSC
Seq Type List	MeRIP-seq; m6A-seq; m6A-CLIP/IP
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864356
mod ID: M6ASITE092132		Click to Show/Hide the Full List
mod site	chrX:73213893-73213894:-		[7]
Sequence	ACATGAATATGTGGATGAGGACGATGGTTATGAGGACTATT
Motif Score	3.616982143
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864357
mod ID: M6ASITE092133		Click to Show/Hide the Full List
mod site	chrX:73213913-73213914:-		[3]
Sequence	GGTAATGAGGAGGGTATGGTACATGAATATGTGGATGAGGA
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864358
mod ID: M6ASITE092134		Click to Show/Hide the Full List
mod site	chrX:73213971-73213972:-		[6]
Sequence	ATATAAATCAGACTCTGAGGACTGTGATGATGAGGAAATGT
Motif Score	4.065041667
Cell/Tissue List	HEK293T; A549; U2OS; H1B; hNPCs; hESCs; fibroblasts; GM12878; Jurkat; MSC
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864359
mod ID: M6ASITE092135		Click to Show/Hide the Full List
mod site	chrX:73213980-73213981:-		[6]
Sequence	GGAATGTGAATATAAATCAGACTCTGAGGACTGTGATGATG
Motif Score	3.319380952
Cell/Tissue List	HEK293T; A549; U2OS; H1B; hNPCs; hESCs; fibroblasts; GM12878; Jurkat; MSC
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864360
mod ID: M6ASITE092136		Click to Show/Hide the Full List
mod site	chrX:73214012-73214013:-		[4]
Sequence	ATCATCAATGCAATCTATGAACCTACAGAAGAGGAATGTGA
Motif Score	2.930744048
Cell/Tissue List	HEK293T; U2OS; hNPCs; hESCs; fibroblasts; Jurkat
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864361
mod ID: M6ASITE092137		Click to Show/Hide the Full List
mod site	chrX:73214088-73214089:-		[5]
Sequence	ATTCCTGAGGGAATTTCATGACATTGAAAGAAAGTTTGCTG
Motif Score	2.859755952
Cell/Tissue List	brain; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864362
mod ID: M6ASITE092138		Click to Show/Hide the Full List
mod site	chrX:73214134-73214135:-		[6]
Sequence	TAGCCCTTAAAAAGCTTCAAACTAGAGCGGCCAATTTAGAA
Motif Score	2.627720238
Cell/Tissue List	HEK293T; A549; U2OS; H1B; hESCs
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864363
mod ID: M6ASITE092139		Click to Show/Hide the Full List
mod site	chrX:73214196-73214197:-		[6]
Sequence	CGGTTATGTTTTAGATACAGACTTTGTTGAAAGTCTACCTG
Motif Score	3.319380952
Cell/Tissue List	HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864364
mod ID: M6ASITE092140		Click to Show/Hide the Full List
mod site	chrX:73214222-73214223:-		[6]
Sequence	GAGGCAGACCGTCCAAAAGGACTTATCGGTTATGTTTTAGA
Motif Score	4.065041667
Cell/Tissue List	HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; Jurkat
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864365
mod ID: M6ASITE092141		Click to Show/Hide the Full List
mod site	chrX:73214235-73214236:-		[6]
Sequence	TGATGAGGACTCAGAGGCAGACCGTCCAAAAGGACTTATCG
Motif Score	2.876744048
Cell/Tissue List	HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; Jurkat
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864366
mod ID: M6ASITE092142		Click to Show/Hide the Full List
mod site	chrX:73214247-73214248:-		[6]
Sequence	AGGTGGCGATACTGATGAGGACTCAGAGGCAGACCGTCCAA
Motif Score	4.065041667
Cell/Tissue List	HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; CD8T; Jurkat
Seq Type List	MeRIP-seq; m6A-seq; m6A-CLIP/IP
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864367
mod ID: M6ASITE092143		Click to Show/Hide the Full List
mod site	chrX:73214405-73214406:-		[4]
Sequence	ATGGTGGAAGGGCTCGGGGAACATCTGGAGCGCGGTGAAGA
Motif Score	2.951386905
Cell/Tissue List	HEK293T; U2OS; H1A; H1B; hESCs
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864368
mod ID: M6ASITE092144		Click to Show/Hide the Full List
mod site	chrX:73214475-73214476:-		[8]
Sequence	AAAAATGGCCGAGTCAGAGAACCGCAAGGAGCTGTCAGAAT
Motif Score	2.930744048
Cell/Tissue List	U2OS
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000373517.3
External Link	RMBase: m6A_site_864369

Ref 1	Clinical pipeline report, company report or official report of SystImmune.
Ref 2	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 3	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 4	Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons. Cell. 2012 Jun 22;149(7):1635-46. doi: 10.1016/j.cell.2012.05.003. Epub 2012 May 17.
Ref 5	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 6	Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus. Nat Commun. 2019 Oct 9;10(1):4595. doi: 10.1038/s41467-019-12504-y.
Ref 7	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 8	RNA-methylation-dependent RNA processing controls the speed of the circadian clock. Cell. 2013 Nov 7;155(4):793-806. doi: 10.1016/j.cell.2013.10.026.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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