m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01704)
Target Name Microtubule-associated protein tau (TAU)
Synonyms
Neurofibrillary tangle protein; Paired helical filament-tau; PHF-tau
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Gene Name Tau
Chromosomal Location 17q21.31
Function
Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity (PubMed:21985311). The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both (PubMed:21985311, PubMed:32961270). Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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Gene ID 4137
Uniprot ID
TAU_HUMAN
HGNC ID
HGNC:6893
KEGG ID
hsa:4137
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
Non-coding RNA
m6A Regulator: YTH domain-containing family protein 1 (YTHDF1)
 Regulator Info 
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05087
 Crosstalk Info 
Epigenetic Regulator DPPA2 upstream binding RNA (DUBR)
Regulated Target YTH domain-containing family protein 1 (YTHDF1)
Crosstalk relationship ncRNA → m6A
m6A Regulator: YTH domain-containing family protein 3 (YTHDF3)
 Regulator Info 
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05088
 Crosstalk Info 
Epigenetic Regulator DPPA2 upstream binding RNA (DUBR)
Regulated Target YTH N6-methyladenosine RNA binding protein F3 (YTHDF3)
Crosstalk relationship ncRNA → m6A
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01704)
Microtubule-associated protein tau (TAU)
Adenosine-to-Inosine editing (A-to-I)
In total 4 m6A sequence/site(s) in this target gene
mod ID: A2ISITE008214 Click to Show/Hide the Full List
mod site chr17:45922092-45922093:+ [2]
Sequence GCCGTGGAGCGATCACTGCAACCTCTGTCTCCCAGGTTCAA
Transcript ID List ENST00000262410.9; ENST00000570299.5; ENST00000351559.9; ENST00000340799.9; ENST00000446361.7; ENST00000571311.5; ENST00000334239.12; ENST00000344290.9; ENST00000535772.5
External Link RMBase: RNA-editing_site_58571
mod ID: A2ISITE008215 Click to Show/Hide the Full List
mod site chr17:45946530-45946531:+ [2]
Sequence ATTGCTTGAACCCGAGAGGTAGAGGTTGCAGTGAGCCGAGA
Transcript ID List ENST00000571311.5; ENST00000344290.9; ENST00000570299.5; ENST00000446361.7; ENST00000535772.5; rmsk_4703617; ENST00000262410.9; ENST00000334239.12; ENST00000351559.9; ENST00000340799.9
External Link RMBase: RNA-editing_site_58572
mod ID: A2ISITE008216 Click to Show/Hide the Full List
mod site chr17:46019558-46019559:+ [2]
Sequence TTGTATTTCCTGTGGAGACGAGGTTTTGCCACGTTGCCCAG
Transcript ID List ENST00000571987.5; ENST00000420682.6; ENST00000415613.6; ENST00000340799.9; ENST00000431008.7; ENST00000446361.7; ENST00000576518.1; ENST00000535772.5; ENST00000334239.12; ENST00000344290.9; ENST00000351559.9; ENST00000262410.9; ENST00000574436.5
External Link RMBase: RNA-editing_site_58573
mod ID: A2ISITE008217 Click to Show/Hide the Full List
mod site chr17:46022830-46022831:+ [2]
Sequence TCCCAGTTGCTCTGGAGGTTAAGGTGGGAAGATTGCTTGAG
Transcript ID List ENST00000340799.9; ENST00000446361.7; ENST00000415613.6; ENST00000574436.5; ENST00000431008.7; ENST00000262410.9; ENST00000351559.9; ENST00000334239.12; ENST00000571987.5; ENST00000576518.1; rmsk_4703778; ENST00000344290.9; ENST00000420682.6; ENST00000535772.5
External Link RMBase: RNA-editing_site_58574
2'-O-Methylation (2'-O-Me)
In total 6 m6A sequence/site(s) in this target gene
mod ID: 2OMSITE000154 Click to Show/Hide the Full List
mod site chr17:45952014-45952015:+ [3]
Sequence GTTTATTTTCCTGTCTGTGTATCGCTTCTCGGCCTTTTGGC
Seq Type List RiboMeth-seq
Transcript ID List ENST00000351559.9; ENST00000344290.9; ENST00000570299.5; ENST00000262410.9; rmsk_4703630; ENST00000571311.5; ENST00000334239.12; ENST00000535772.5; ENST00000340799.9; ENST00000446361.7
External Link RMBase: Nm_site_2491
mod ID: 2OMSITE000156 Click to Show/Hide the Full List
mod site chr17:45952024-45952025:+ [3]
Sequence CTGTCTGTGTATCGCTTCTCGGCCTTTTGGCTAAGATCAAG
Seq Type List RiboMeth-seq
Transcript ID List rmsk_4703630; ENST00000570299.5; ENST00000571311.5; ENST00000351559.9; ENST00000446361.7; ENST00000334239.12; ENST00000340799.9; ENST00000262410.9; ENST00000535772.5; ENST00000344290.9
External Link RMBase: Nm_site_2493
mod ID: 2OMSITE000157 Click to Show/Hide the Full List
mod site chr17:45952025-45952026:+ [3]
Sequence TGTCTGTGTATCGCTTCTCGGCCTTTTGGCTAAGATCAAGT
Seq Type List RiboMeth-seq
Transcript ID List ENST00000340799.9; ENST00000446361.7; ENST00000344290.9; ENST00000262410.9; rmsk_4703630; ENST00000571311.5; ENST00000535772.5; ENST00000570299.5; ENST00000334239.12; ENST00000351559.9
External Link RMBase: Nm_site_2494
mod ID: 2OMSITE000158 Click to Show/Hide the Full List
mod site chr17:45952032-45952033:+ [3]
Sequence GTATCGCTTCTCGGCCTTTTGGCTAAGATCAAGTGTATTTT
Seq Type List RiboMeth-seq
Transcript ID List ENST00000344290.9; rmsk_4703630; ENST00000262410.9; ENST00000446361.7; ENST00000535772.5; ENST00000570299.5; ENST00000340799.9; ENST00000334239.12; ENST00000351559.9; ENST00000571311.5
External Link RMBase: Nm_site_2495
mod ID: 2OMSITE000159 Click to Show/Hide the Full List
mod site chr17:45952038-45952039:+ [3]
Sequence CTTCTCGGCCTTTTGGCTAAGATCAAGTGTATTTTCCTGTC
Seq Type List RiboMeth-seq
Transcript ID List ENST00000262410.9; ENST00000446361.7; ENST00000571311.5; ENST00000340799.9; ENST00000570299.5; ENST00000344290.9; rmsk_4703630; ENST00000535772.5; ENST00000351559.9; ENST00000334239.12
External Link RMBase: Nm_site_2496
mod ID: 2OMSITE000155 Click to Show/Hide the Full List
mod site chr17:45952015-45952016:+ [3]
Sequence TTTATTTTCCTGTCTGTGTATCGCTTCTCGGCCTTTTGGCT
Seq Type List RiboMeth-seq
Transcript ID List ENST00000262410.9; ENST00000344290.9; ENST00000334239.12; ENST00000340799.9; rmsk_4703630; ENST00000571311.5; ENST00000446361.7; ENST00000351559.9; ENST00000570299.5; ENST00000535772.5
External Link RMBase: Nm_site_2492
Other RNA modification (m2,2,7Gpp(pN))
In total 1 m6A sequence/site(s) in this target gene
mod ID: RNASITE000006 Click to Show/Hide the Full List
mod site chr17:45952013-45952014:+ [4]
Sequence TGTTTATTTTCCTGTCTGTGTATCGCTTCTCGGCCTTTTGG
Transcript ID List ENST00000334239.12; ENST00000535772.5; ENST00000446361.7; ENST00000344290.9; ENST00000262410.9; ENST00000340799.9; ENST00000351559.9; ENST00000571311.5; ENST00000570299.5
External Link RMBase: otherMod_site_528
5-methylcytidine (m5C)
In total 4 m6A sequence/site(s) in this target gene
mod ID: M5CSITE001198 Click to Show/Hide the Full List
mod site chr17:45894592-45894593:+ [5]
Sequence AGCTCCGGCACCAACAGCAGCGCCGCTGCCACCGCCCACCT
Seq Type List Bisulfite-seq
Transcript ID List ENST00000344290.9; ENST00000571311.5; ENST00000340799.9; ENST00000262410.9; ENST00000351559.9; ENST00000535772.5; ENST00000570299.5
External Link RMBase: m5C_site_19293
mod ID: M5CSITE001199 Click to Show/Hide the Full List
mod site chr17:45974437-45974438:+ [5]
Sequence CCGGCAAGCAGGCTGCCGCGCAGCCCCACACGGAGATCCCA
Seq Type List Bisulfite-seq
Transcript ID List ENST00000415613.6; ENST00000570299.5; ENST00000340799.9; ENST00000574436.5; ENST00000431008.7; ENST00000571987.5; ENST00000262410.9; ENST00000576518.1; ENST00000344290.9; ENST00000351559.9; ENST00000571311.5; ENST00000446361.7; ENST00000420682.6; ENST00000535772.5; ENST00000334239.12
External Link RMBase: m5C_site_19294
mod ID: M5CSITE001200 Click to Show/Hide the Full List
mod site chr17:45999546-45999547:+
Sequence GCAGCAGGAATGGGGCTGAGCAGGGAAGACAACTTTCCATT
Cell/Tissue List frontalcortex
Seq Type List Bisulfite-seq
Transcript ID List ENST00000574436.5; ENST00000571987.5; ENST00000351559.9; ENST00000576518.1; ENST00000420682.6; ENST00000446361.7; ENST00000431008.7; ENST00000262410.9; ENST00000334239.12; ENST00000537309.1; ENST00000344290.9; ENST00000535772.5; ENST00000570299.5; ENST00000415613.6; ENST00000340799.9
External Link RMBase: m5C_site_19295
mod ID: M5CSITE001201 Click to Show/Hide the Full List
mod site chr17:46026924-46026925:+
Sequence AGGGACTTGGCAGTAGAAATCCAGGGCCTCCCCTGGGGCTG
Cell/Tissue List muscle
Seq Type List Bisulfite-seq
Transcript ID List ENST00000262410.9; ENST00000344290.9; ENST00000535772.5; ENST00000340799.9; ENST00000351559.9; ENST00000446361.7
External Link RMBase: m5C_site_19296
N6-methyladenosine (m6A)
In total 14 m6A sequence/site(s) in this target gene
mod ID: M6ASITE033462 Click to Show/Hide the Full List
mod site chr17:45991486-45991487:+ [6]
Sequence ATGGTAAAACGAAGATCGCCACACCGCGGGGAGCAGCCCCT
Motif Score 2.053113095
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000571987.5; ENST00000431008.7; ENST00000351559.9; ENST00000535772.5; ENST00000420682.6; ENST00000446361.7; ENST00000262410.9; ENST00000570299.5; ENST00000574436.5; ENST00000576518.1; ENST00000344290.9; ENST00000334239.12; ENST00000340799.9; ENST00000415613.6
External Link RMBase: m6A_site_367793
mod ID: M6ASITE033463 Click to Show/Hide the Full List
mod site chr17:45991570-45991571:+ [6]
Sequence AAACCCCGCCCGCTCCAAAGACACCACCCAGCTCTGGTAAG
Motif Score 2.897386905
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000570299.5; ENST00000576518.1; ENST00000340799.9; ENST00000420682.6; ENST00000334239.12; ENST00000574436.5; ENST00000431008.7; ENST00000571987.5; ENST00000446361.7; ENST00000415613.6; ENST00000262410.9; ENST00000351559.9; ENST00000535772.5; ENST00000344290.9
External Link RMBase: m6A_site_367794
mod ID: M6ASITE033464 Click to Show/Hide the Full List
mod site chr17:46014255-46014256:+ [6]
Sequence TCTCCAGGTGCAAATAGTCTACAAACCAGTTGACCTGAGCA
Motif Score 2.078666667
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000262410.9; ENST00000570299.5; ENST00000571987.5; ENST00000415613.6; ENST00000446361.7; ENST00000340799.9; ENST00000334239.12; ENST00000420682.6; ENST00000431008.7; ENST00000351559.9; ENST00000576518.1; ENST00000574436.5; ENST00000535772.5; ENST00000344290.9
External Link RMBase: m6A_site_367795
mod ID: M6ASITE033465 Click to Show/Hide the Full List
mod site chr17:46014306-46014307:+ [6]
Sequence CAAGTGTGGCTCATTAGGCAACATCCATCATAAACCAGGTA
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000344290.9; ENST00000571987.5; ENST00000576518.1; ENST00000574436.5; ENST00000535772.5; ENST00000334239.12; ENST00000446361.7; ENST00000431008.7; ENST00000570299.5; ENST00000420682.6; ENST00000262410.9; ENST00000340799.9; ENST00000351559.9; ENST00000415613.6
External Link RMBase: m6A_site_367796
mod ID: M6ASITE033466 Click to Show/Hide the Full List
mod site chr17:46018692-46018693:+ [6]
Sequence GTCGAAGATTGGGTCCCTGGACAATATCACCCACGTCCCTG
Motif Score 3.643047619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000446361.7; ENST00000415613.6; ENST00000420682.6; ENST00000535772.5; ENST00000576518.1; ENST00000351559.9; ENST00000431008.7; ENST00000570299.5; ENST00000574436.5; ENST00000344290.9; ENST00000340799.9; ENST00000571987.5; ENST00000334239.12; ENST00000262410.9
External Link RMBase: m6A_site_367797
mod ID: M6ASITE033467 Click to Show/Hide the Full List
mod site chr17:46024049-46024050:+ [6]
Sequence GTCGCCAGTGGTGTCTGGGGACACGTCTCCACGGCATCTCA
Motif Score 3.643047619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000415613.6; ENST00000431008.7; ENST00000576518.1; ENST00000262410.9; ENST00000574436.5; ENST00000571987.5; ENST00000420682.6; ENST00000340799.9; ENST00000351559.9; ENST00000446361.7; ENST00000535772.5; ENST00000344290.9; ENST00000334239.12
External Link RMBase: m6A_site_367798
mod ID: M6ASITE033468 Click to Show/Hide the Full List
mod site chr17:46024097-46024098:+ [6]
Sequence CTCCTCCACCGGCAGCATCGACATGGTAGACTCGCCCCAGC
Motif Score 2.865571429
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000262410.9; ENST00000571987.5; ENST00000431008.7; ENST00000574436.5; ENST00000535772.5; ENST00000415613.6; ENST00000344290.9; ENST00000334239.12; ENST00000446361.7; ENST00000351559.9; ENST00000420682.6; ENST00000340799.9; ENST00000576518.1
External Link RMBase: m6A_site_367799
mod ID: M6ASITE033469 Click to Show/Hide the Full List
mod site chr17:46025986-46025987:+ [6]
Sequence GCTGGAGCAGCTGAACATATACATAGATGTTGCCCTGCCCT
Motif Score 2.110482143
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000262410.9; ENST00000344290.9; ENST00000446361.7; ENST00000535772.5; ENST00000351559.9; ENST00000340799.9
External Link RMBase: m6A_site_367800
mod ID: M6ASITE033470 Click to Show/Hide the Full List
mod site chr17:46026175-46026176:+ [6]
Sequence ACGAGGTGTCTCTCACCCCCACACTGGGACTCGTGTGGCCT
Motif Score 2.053113095
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000446361.7; ENST00000535772.5; ENST00000351559.9; ENST00000340799.9; ENST00000262410.9; ENST00000344290.9
External Link RMBase: m6A_site_367801
mod ID: M6ASITE033471 Click to Show/Hide the Full List
mod site chr17:46026728-46026729:+ [6]
Sequence ATGACTTGACAAGTCAGGAGACACTGTTCCCAAAGCCTTGA
Motif Score 2.897386905
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000340799.9; ENST00000351559.9; ENST00000446361.7; ENST00000344290.9; ENST00000262410.9; ENST00000535772.5
External Link RMBase: m6A_site_367802
mod ID: M6ASITE033472 Click to Show/Hide the Full List
mod site chr17:46026777-46026778:+ [6]
Sequence CCTCAGCCCGCTGACCTTGCACAAACTCCATCTGCTGCCAT
Motif Score 2.830589286
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000340799.9; ENST00000535772.5; ENST00000262410.9; ENST00000344290.9; ENST00000351559.9; ENST00000446361.7
External Link RMBase: m6A_site_367803
mod ID: M6ASITE033473 Click to Show/Hide the Full List
mod site chr17:46026824-46026825:+ [7]
Sequence AGGGAAGCCGCCTTTGCAAAACATTGCTGCCTAAAGAAACT
Motif Score 2.20572619
Cell/Tissue List brain
Seq Type List m6A-REF-seq
Transcript ID List ENST00000351559.9; ENST00000535772.5; ENST00000340799.9; ENST00000344290.9; ENST00000262410.9; ENST00000446361.7
External Link RMBase: m6A_site_367804
mod ID: M6ASITE033474 Click to Show/Hide the Full List
mod site chr17:46027344-46027345:+ [6]
Sequence GCTTGTGATCTTAAATGAGGACAATCCCCCCAGGGCTGGGC
Motif Score 3.643047619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000262410.9; ENST00000351559.9; ENST00000446361.7; ENST00000340799.9; ENST00000344290.9; ENST00000535772.5
External Link RMBase: m6A_site_367805
mod ID: M6ASITE033475 Click to Show/Hide the Full List
mod site chr17:46027705-46027706:+ [7]
Sequence GGGGTTTCTCTTTTCCACTGACAGGCTTTCCCAGGCAGCTG
Motif Score 2.859755952
Cell/Tissue List brain
Seq Type List m6A-REF-seq
Transcript ID List ENST00000535772.5; ENST00000351559.9; ENST00000446361.7; ENST00000340799.9; ENST00000344290.9; ENST00000262410.9
External Link RMBase: m6A_site_367806
Pseudouridine (Pseudo)
In total 3 m6A sequence/site(s) in this target gene
mod ID: PSESITE000094 Click to Show/Hide the Full List
mod site chr17:45952019-45952020:+ [4]
Sequence TTTTCCTGTCTGTGTATCGCTTCTCGGCCTTTTGGCTAAGA
Transcript ID List ENST00000571311.5; rmsk_4703630; ENST00000262410.9; ENST00000446361.7; ENST00000535772.5; ENST00000340799.9; ENST00000570299.5; ENST00000351559.9; ENST00000344290.9; ENST00000334239.12
External Link RMBase: Pseudo_site_2203
mod ID: PSESITE000095 Click to Show/Hide the Full List
mod site chr17:45952020-45952021:+ [8]
Sequence TTTCCTGTCTGTGTATCGCTTCTCGGCCTTTTGGCTAAGAT
Transcript ID List ENST00000344290.9; ENST00000570299.5; rmsk_4703630; ENST00000446361.7; ENST00000340799.9; ENST00000571311.5; ENST00000334239.12; ENST00000535772.5; ENST00000351559.9; ENST00000262410.9
External Link RMBase: Pseudo_site_2204
mod ID: PSESITE000096 Click to Show/Hide the Full List
mod site chr17:45952028-45952029:+ [4]
Sequence CTGTGTATCGCTTCTCGGCCTTTTGGCTAAGATCAAGTGTA
Transcript ID List ENST00000351559.9; ENST00000344290.9; rmsk_4703630; ENST00000340799.9; ENST00000446361.7; ENST00000570299.5; ENST00000571311.5; ENST00000262410.9; ENST00000535772.5; ENST00000334239.12
External Link RMBase: Pseudo_site_2205