m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01603)

Target Name	HOX transcript antisense RNA (HOTAIR)
Synonyms	HOXC-AS4; HOXC11-AS1; NCRNA00072; HOXC cluster antisense RNA 4 (non-protein coding); HOX transcript antisense RNA (non-protein coding) Click to Show/Hide
Gene Name	HOTAIR
Chromosomal Location	12q13.13
Gene ID	100124700
HGNC ID	HGNC:33510

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Histone modification

m6A Regulator: Methyltransferase-like 14 (METTL14)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03063		Crosstalk Info
Epigenetic Regulator	Lysine-specific histone demethylase 1A (KDM1A)
Regulated Target	Histone H3 lysine 4 monomethylation (H3K4me1)
Crosstalk relationship	m6A → Histone modification
Disease	Disorders due to use of opioids	Disease Info
Drug	MM-102	Drug Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01603)

HOX transcript antisense RNA (HOTAIR)

N6-methyladenosine (m6A)

In total 39 m6A sequence/site(s) in this target gene
mod ID: M6ASITE012963		Click to Show/Hide the Full List
mod site	chr12:53962615-53962616:-		[2]
Sequence	GTGTCTTAAACAGTTCATGAACCCAGAAGAATGCAATTTCA
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq; DART-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190692
mod ID: M6ASITE012964		Click to Show/Hide the Full List
mod site	chr12:53962626-53962627:-		[2]
Sequence	GCTAGAGAATTGTGTCTTAAACAGTTCATGAACCCAGAAGA
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190693
mod ID: M6ASITE012965		Click to Show/Hide the Full List
mod site	chr12:53962668-53962669:-		[2]
Sequence	TTACCATTCCCAATGCCTGAACTTCCTCCTGCTATTAAGAT
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190694
mod ID: M6ASITE012966		Click to Show/Hide the Full List
mod site	chr12:53962714-53962715:-		[2]
Sequence	AATAATAGAAGTACAGAAGAACAGAAAAAAAATCAGCAGAT
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190695
mod ID: M6ASITE012967		Click to Show/Hide the Full List
mod site	chr12:53962739-53962740:-		[2]
Sequence	ACAGAAGGGGTATTTAAAAGACAGAAATAATAGAAGTACAG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190696
mod ID: M6ASITE012968		Click to Show/Hide the Full List
mod site	chr12:53962761-53962762:-		[2]
Sequence	TAAATAAGTGATGCATGTAGACACAGAAGGGGTATTTAAAA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190697
mod ID: M6ASITE012969		Click to Show/Hide the Full List
mod site	chr12:53962786-53962787:-		[2]
Sequence	AGAAAAATAGACATAGGAGAACACTTAAATAAGTGATGCAT
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190698
mod ID: M6ASITE012970		Click to Show/Hide the Full List
mod site	chr12:53962796-53962797:-		[2]
Sequence	AAGTTGCAGTAGAAAAATAGACATAGGAGAACACTTAAATA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; MSC
Seq Type List	m6A-seq; MeRIP-seq; DART-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190699
mod ID: M6ASITE012971		Click to Show/Hide the Full List
mod site	chr12:53962820-53962821:-		[2]
Sequence	AATATAGACCCCAGCTTGGGACAAAAGTTGCAGTAGAAAAA
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190700
mod ID: M6ASITE012972		Click to Show/Hide the Full List
mod site	chr12:53962833-53962834:-		[2]
Sequence	ACTTTGCACTCTAAATATAGACCCCAGCTTGGGACAAAAGT
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190701
mod ID: M6ASITE012973		Click to Show/Hide the Full List
mod site	chr12:53962853-53962854:-		[2]
Sequence	GGGACCCTGCTGCAAACGGGACTTTGCACTCTAAATATAGA
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190702
mod ID: M6ASITE012974		Click to Show/Hide the Full List
mod site	chr12:53962870-53962871:-		[2]
Sequence	AGGAGTGATTATGCAGTGGGACCCTGCTGCAAACGGGACTT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEK293T; MSC
Seq Type List	m6A-seq; MeRIP-seq; DART-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190703
mod ID: M6ASITE012975		Click to Show/Hide the Full List
mod site	chr12:53962929-53962930:-		[2]
Sequence	CTAGAAGAATGCATCTTGAGACACATGGGTAACCTAATTAT
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190704
mod ID: M6ASITE012976		Click to Show/Hide the Full List
mod site	chr12:53963013-53963014:-		[3]
Sequence	CTGTTACACGCCTCTCCAAGACACAGTGGCACCGCTTTTCT
Motif Score	2.897386905
Cell/Tissue List	HEK293T; HeLa
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190705
mod ID: M6ASITE012977		Click to Show/Hide the Full List
mod site	chr12:53963092-53963093:-		[3]
Sequence	AACAAATTTTTAAAAGTGAAACCAGCCCTAGCCTTTGGAAG
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190706
mod ID: M6ASITE012978		Click to Show/Hide the Full List
mod site	chr12:53963111-53963112:-		[3]
Sequence	CCTAGACTTAAGATTCAAAAACAAATTTTTAAAAGTGAAAC
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190707
mod ID: M6ASITE012979		Click to Show/Hide the Full List
mod site	chr12:53963198-53963199:-		[4]
Sequence	GTCCCGGCTGGATGCAGGGGACTTGAGCTGCTCCGGAATTT
Motif Score	4.065041667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190708
mod ID: M6ASITE012980		Click to Show/Hide the Full List
mod site	chr12:53963289-53963290:-		[4]
Sequence	TAGGAAAGCCTTTCCCTGCTACTTGTGTAGACCCAGCCCAA
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190709
mod ID: M6ASITE012981		Click to Show/Hide the Full List
mod site	chr12:53963512-53963513:-		[2]
Sequence	CGGAACCCATGGACTCATAAACAATATATCTGTTGGGCGTG
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190710
mod ID: M6ASITE012982		Click to Show/Hide the Full List
mod site	chr12:53963520-53963521:-		[2]
Sequence	CGTCTACACGGAACCCATGGACTCATAAACAATATATCTGT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190711
mod ID: M6ASITE012983		Click to Show/Hide the Full List
mod site	chr12:53963528-53963529:-		[2]
Sequence	TATGGCGGCGTCTACACGGAACCCATGGACTCATAAACAAT
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190712
mod ID: M6ASITE012984		Click to Show/Hide the Full List
mod site	chr12:53963557-53963558:-		[2]
Sequence	TAATTAATTGATTCCTTTGGACTGTAAAATATGGCGGCGTC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190713
mod ID: M6ASITE012985		Click to Show/Hide the Full List
mod site	chr12:53963589-53963590:-		[2]
Sequence	GAGCAGCGGTCGGTGGGGGGACTGGGAGGCGCTAATTAATT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190714
mod ID: M6ASITE012986		Click to Show/Hide the Full List
mod site	chr12:53963657-53963658:-		[2]
Sequence	TGATGAGGCTTGTTAACAAGACCAGAGAGCTGGCCAAGCAC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5
External Link	RMBase: m6A_site_190715
mod ID: M6ASITE012987		Click to Show/Hide the Full List
mod site	chr12:53963799-53963800:-		[2]
Sequence	GCCCAGAGAACGCTGGAAAAACCTGAGCGGGTGCCGGGGCA
Motif Score	2.185083333
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000455246.5; ENST00000424518.5
External Link	RMBase: m6A_site_190716
mod ID: M6ASITE012988		Click to Show/Hide the Full List
mod site	chr12:53963858-53963859:-		[4]
Sequence	AAAATCTAGGGAACGGGAGTACAGAGAGAATAATCCGGGTC
Motif Score	2.856142857
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000425595.5; ENST00000455246.5; ENST00000424518.5
External Link	RMBase: m6A_site_190717
mod ID: M6ASITE012989		Click to Show/Hide the Full List
mod site	chr12:53963938-53963939:-		[2]
Sequence	GGCAAGACGGGCACTCACAGACAGAGGTTTATGTATTTTTA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; GSC-11
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000455246.5; ENST00000424518.5; ENST00000425595.5; ENST00000453875.5
External Link	RMBase: m6A_site_190718
mod ID: M6ASITE012990		Click to Show/Hide the Full List
mod site	chr12:53963973-53963974:-		[2]
Sequence	GCAAGGCGGCAGTTCCCGGAACAAACGTGGCAGAGGGCAAG
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; GSC-11; endometrial; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000453875.5; ENST00000424518.5; ENST00000425595.5; ENST00000455246.5
External Link	RMBase: m6A_site_190719
mod ID: M6ASITE012991		Click to Show/Hide the Full List
mod site	chr12:53964020-53964021:-		[2]
Sequence	CCAGACGAAGGTGAAAGCGAACCACGCAGAGAAATGCAGGC
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T; Huh7; GSC-11; endometrial; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5; ENST00000453875.5; ENST00000455246.5; ENST00000425595.5
External Link	RMBase: m6A_site_190720
mod ID: M6ASITE012992		Click to Show/Hide the Full List
mod site	chr12:53964248-53964249:-		[2]
Sequence	AGAGAAGTGCTGCAACCTAAACCAGCAATTACACCCAAGGT
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000455246.5; ENST00000439545.1; ENST00000425595.5; ENST00000424518.5; ENST00000453875.5
External Link	RMBase: m6A_site_190721
mod ID: M6ASITE012993		Click to Show/Hide the Full List
mod site	chr12:53966291-53966292:-		[5]
Sequence	GAGAGAGGGAGCCCAGAGTTACAGACGGCGGCGAGAGGTAC
Motif Score	2.07285119
Cell/Tissue List	HEK293
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000424518.5; ENST00000453875.5; ENST00000439545.1; ENST00000425595.5; ENST00000455246.5
External Link	RMBase: m6A_site_190722
mod ID: M6ASITE012994		Click to Show/Hide the Full List
mod site	chr12:53967311-53967312:-		[6]
Sequence	GGCTCCCACCCGGGACTTAGACCCTCAGGTCCCTAATATCC
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000453875.5; ENST00000455246.5; ENST00000424518.5; ENST00000439545.1
External Link	RMBase: m6A_site_190723
mod ID: M6ASITE012995		Click to Show/Hide the Full List
mod site	chr12:53967317-53967318:-		[6]
Sequence	CCTGGCGGCTCCCACCCGGGACTTAGACCCTCAGGTCCCTA
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5; ENST00000455246.5; ENST00000439545.1; ENST00000453875.5
External Link	RMBase: m6A_site_190724
mod ID: M6ASITE012996		Click to Show/Hide the Full List
mod site	chr12:53967352-53967353:-		[2]
Sequence	GAGGCCTGGGAGTTCCACAGACCAACACCCCTGCTCCTGGC
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000453875.5; ENST00000455246.5; ENST00000424518.5; ENST00000439545.1
External Link	RMBase: m6A_site_190725
mod ID: M6ASITE012997		Click to Show/Hide the Full List
mod site	chr12:53968628-53968629:-		[2]
Sequence	CGAAAGCTTCCACAGTGAGGACTGCTCCGTGGGGTGAGTGT
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000424518.5; ENST00000455246.5; ENST00000439545.1
External Link	RMBase: m6A_site_190726
mod ID: M6ASITE012998		Click to Show/Hide the Full List
mod site	chr12:53968680-53968681:-		[2]
Sequence	GCCTAGGCAGGCAGTGGGGAACTCTGACTCGCCTGTGCTCT
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000439545.1; ENST00000424518.5; ENST00000455246.5
External Link	RMBase: m6A_site_190727
mod ID: M6ASITE012999		Click to Show/Hide the Full List
mod site	chr12:53968708-53968709:-		[2]
Sequence	ATTCTGCCCTGATTTCCGGAACCTGGAAGCCTAGGCAGGCA
Motif Score	2.930744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000439545.1; ENST00000424518.5; ENST00000455246.5
External Link	RMBase: m6A_site_190728
mod ID: M6ASITE013000		Click to Show/Hide the Full List
mod site	chr12:53968810-53968811:-		[2]
Sequence	TCCAGTCACCAAAAACAAAAACAAAAAAAAATCTTTTGCCC
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000439545.1; ENST00000424518.5; ENST00000455246.5
External Link	RMBase: m6A_site_190729
mod ID: M6ASITE013001		Click to Show/Hide the Full List
mod site	chr12:53968816-53968817:-		[2]
Sequence	AAAGATTCCAGTCACCAAAAACAAAAACAAAAAAAAATCTT
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000424518.5; ENST00000439545.1; ENST00000455246.5
External Link	RMBase: m6A_site_190730

Ref 1	CDP571, a humanized monoclonal antibody to tumour necrosis factor-alpha, for steroid-dependent Crohn's disease: a randomized, double-blind, placebo-controlled trial. Aliment Pharmacol Ther. 2006 Mar 1;23(5):617-28. doi: 10.1111/j.1365-2036.2006.02791.x.
Ref 2	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 3	N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505(7481):117-20. doi: 10.1038/nature12730. Epub 2013 Nov 27.
Ref 4	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 5	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 6	RNA m(6)A methylation regulates the epithelial mesenchymal transition of cancer cells and translation of Snail. Nat Commun. 2019 May 6;10(1):2065. doi: 10.1038/s41467-019-09865-9.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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