m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01518)

Target Name	LIM domain-containing protein ajuba (AJUBA)
Gene Name	AJUBA
Chromosomal Location	14q11.2
Family	Zyxin/ajuba family
Function	Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, mitosis, cell-cell adhesion, cell differentiation, proliferation and migration. Contributes to the linking and/or strengthening of epithelia cell-cell junctions in part by linking adhesive receptors to the actin cytoskeleton. May be involved in signal transduction from cell adhesion sites to the nucleus. Plays an important role in regulation of the kinase activity of AURKA for mitotic commitment. Also a component of the IL-1 signaling pathway modulating IL-1-induced NFKB1 activation by influencing the assembly and activity of the PRKCZ-SQSTM1-TRAF6 multiprotein signaling complex. Functions as an HDAC-dependent corepressor for a subset of GFI1 target genes. Acts as a transcriptional corepressor for SNAI1 and SNAI2/SLUG-dependent repression of E-cadherin transcription. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Positively regulates microRNA (miRNA)-mediated gene silencing. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Click to Show/Hide
Gene ID	84962
Uniprot ID	AJUBA_HUMAN
HGNC ID	HGNC:20250
KEGG ID	hsa:84962

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

RNA modification

m6A Regulator: Methyltransferase-like 3 (METTL3)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT00004		Crosstalk Info
Epigenetic Regulator	Interferon-inducible protein 4 (ADAR1)
Regulated Target	LIM domain-containing protein ajuba (AJUBA)
Crosstalk relationship	m6A → A-to-I

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01518)

LIM domain-containing protein ajuba (AJUBA)

Adenosine-to-Inosine editing (A-to-I)

In total 25 m6A sequence/site(s) in this target gene
mod ID: A2ISITE006262		Click to Show/Hide the Full List
mod site	chr14:22971540-22971541:-		[2]
Sequence	ATTTGATAAATATTTATTTTAGACTAATTGGTTTTAGGTGA
Transcript ID List	ENST00000262713.7; ENST00000555074.1
External Link	RMBase: RNA-editing_site_37073
mod ID: A2ISITE006263		Click to Show/Hide the Full List
mod site	chr14:22972166-22972167:-		[3]
Sequence	TAGTCAGTTTGCTTGAAACTAGTTCACCTAAAGCTAGATCT
Transcript ID List	ENST00000397388.7; ENST00000555074.1; ENST00000361265.8; ENST00000262713.7
External Link	RMBase: RNA-editing_site_37074
mod ID: A2ISITE006264		Click to Show/Hide the Full List
mod site	chr14:22972170-22972171:-		[4]
Sequence	ATACTAGTCAGTTTGCTTGAAACTAGTTCACCTAAAGCTAG
Transcript ID List	ENST00000397388.7; ENST00000555074.1; ENST00000262713.7; ENST00000361265.8
External Link	RMBase: RNA-editing_site_37075
mod ID: A2ISITE006265		Click to Show/Hide the Full List
mod site	chr14:22972185-22972186:-		[3]
Sequence	CAAAACACTGATTTGATACTAGTCAGTTTGCTTGAAACTAG
Transcript ID List	ENST00000397388.7; ENST00000555074.1; ENST00000361265.8; ENST00000262713.7
External Link	RMBase: RNA-editing_site_37076
mod ID: A2ISITE006266		Click to Show/Hide the Full List
mod site	chr14:22972211-22972212:-		[4]
Sequence	CTAGAGTTGGGGGGAACTGGAGGGAGCAAAACACTGATTTG
Transcript ID List	ENST00000361265.8; ENST00000262713.7; ENST00000555074.1; ENST00000397388.7
External Link	RMBase: RNA-editing_site_37077
mod ID: A2ISITE006267		Click to Show/Hide the Full List
mod site	chr14:22972229-22972230:-		[2]
Sequence	TCCATCACAATCCCAAAACTAGAGTTGGGGGGAACTGGAGG
Transcript ID List	ENST00000262713.7; ENST00000555074.1; ENST00000397388.7; ENST00000361265.8
External Link	RMBase: RNA-editing_site_37078
mod ID: A2ISITE006268		Click to Show/Hide the Full List
mod site	chr14:22972232-22972233:-		[2]
Sequence	GCATCCATCACAATCCCAAAACTAGAGTTGGGGGGAACTGG
Transcript ID List	ENST00000361265.8; ENST00000555074.1; ENST00000262713.7; ENST00000397388.7
External Link	RMBase: RNA-editing_site_37079
mod ID: A2ISITE006269		Click to Show/Hide the Full List
mod site	chr14:22972233-22972234:-		[2]
Sequence	TGCATCCATCACAATCCCAAAACTAGAGTTGGGGGGAACTG
Transcript ID List	ENST00000555074.1; ENST00000262713.7; ENST00000397388.7; ENST00000361265.8
External Link	RMBase: RNA-editing_site_37080
mod ID: A2ISITE006270		Click to Show/Hide the Full List
mod site	chr14:22972234-22972235:-		[4]
Sequence	TTGCATCCATCACAATCCCAAAACTAGAGTTGGGGGGAACT
Transcript ID List	ENST00000555074.1; ENST00000262713.7; ENST00000397388.7; ENST00000361265.8
External Link	RMBase: RNA-editing_site_37081
mod ID: A2ISITE006271		Click to Show/Hide the Full List
mod site	chr14:22972240-22972241:-		[4]
Sequence	CCCGGATTGCATCCATCACAATCCCAAAACTAGAGTTGGGG
Transcript ID List	ENST00000555074.1; ENST00000361265.8; ENST00000397388.7; ENST00000262713.7
External Link	RMBase: RNA-editing_site_37082
mod ID: A2ISITE006272		Click to Show/Hide the Full List
mod site	chr14:22972266-22972267:-		[4]
Sequence	GCTCACTTGCCACCTCTCAGAGGGGTCCCGGATTGCATCCA
Transcript ID List	ENST00000262713.7; ENST00000397388.7; ENST00000555074.1; ENST00000361265.8
External Link	RMBase: RNA-editing_site_37083
mod ID: A2ISITE006273		Click to Show/Hide the Full List
mod site	chr14:22972268-22972269:-		[2]
Sequence	AAGCTCACTTGCCACCTCTCAGAGGGGTCCCGGATTGCATC
Transcript ID List	ENST00000361265.8; ENST00000555074.1; ENST00000262713.7; ENST00000397388.7
External Link	RMBase: RNA-editing_site_37084
mod ID: A2ISITE006274		Click to Show/Hide the Full List
mod site	chr14:22972293-22972294:-		[2]
Sequence	ACTTGTACACTTGGTTTCCTAGTAGAAGCTCACTTGCCACC
Transcript ID List	ENST00000555074.1; ENST00000361265.8; ENST00000397388.7; ENST00000262713.7
External Link	RMBase: RNA-editing_site_37085
mod ID: A2ISITE006275		Click to Show/Hide the Full List
mod site	chr14:22972329-22972330:-		[4]
Sequence	TCTCTCTCTCACTCTTTCTTACTCTCTTCTCAGGTCACTTG
Transcript ID List	ENST00000361265.8; ENST00000555074.1; ENST00000262713.7; ENST00000397388.7
External Link	RMBase: RNA-editing_site_37086
mod ID: A2ISITE006276		Click to Show/Hide the Full List
mod site	chr14:22972818-22972819:-		[2]
Sequence	GTGGGATGTCCCTGAGAGGTAGCAAGTCTAGGGTGGTGAGT
Transcript ID List	ENST00000397388.7; ENST00000555074.1; ENST00000361265.8; ENST00000262713.7
External Link	RMBase: RNA-editing_site_37087
mod ID: A2ISITE006277		Click to Show/Hide the Full List
mod site	chr14:22972841-22972842:-		[2]
Sequence	TTTGGGGTTGTGGTTGATGCAGTGTGGGATGTCCCTGAGAG
Transcript ID List	ENST00000397388.7; ENST00000262713.7; ENST00000361265.8; ENST00000555074.1
External Link	RMBase: RNA-editing_site_37088
mod ID: A2ISITE006278		Click to Show/Hide the Full List
mod site	chr14:22972899-22972900:-		[4]
Sequence	ACTGACTAGAACCAAATCAAAGTGTAATTCTCCCTCCAGCT
Transcript ID List	ENST00000262713.7; ENST00000397388.7; ENST00000361265.8; ENST00000555074.1
External Link	RMBase: RNA-editing_site_37089
mod ID: A2ISITE006279		Click to Show/Hide the Full List
mod site	chr14:22972904-22972905:-		[4]
Sequence	GCTAAACTGACTAGAACCAAATCAAAGTGTAATTCTCCCTC
Transcript ID List	ENST00000555074.1; ENST00000262713.7; ENST00000397388.7; ENST00000361265.8
External Link	RMBase: RNA-editing_site_37090
mod ID: A2ISITE006280		Click to Show/Hide the Full List
mod site	chr14:22972905-22972906:-		[4]
Sequence	AGCTAAACTGACTAGAACCAAATCAAAGTGTAATTCTCCCT
Transcript ID List	ENST00000397388.7; ENST00000555074.1; ENST00000361265.8; ENST00000262713.7
External Link	RMBase: RNA-editing_site_37091
mod ID: A2ISITE006281		Click to Show/Hide the Full List
mod site	chr14:22972912-22972913:-		[5]
Sequence	TAGTTTCAGCTAAACTGACTAGAACCAAATCAAAGTGTAAT
Transcript ID List	ENST00000555074.1; ENST00000361265.8; ENST00000262713.7; ENST00000397388.7
External Link	RMBase: RNA-editing_site_37092
mod ID: A2ISITE006282		Click to Show/Hide the Full List
mod site	chr14:22972920-22972921:-		[4]
Sequence	AAATCAATTAGTTTCAGCTAAACTGACTAGAACCAAATCAA
Transcript ID List	ENST00000397388.7; ENST00000262713.7; ENST00000555074.1; ENST00000361265.8
External Link	RMBase: RNA-editing_site_37093
mod ID: A2ISITE006283		Click to Show/Hide the Full List
mod site	chr14:22972938-22972939:-		[2]
Sequence	AGTAGAGGACCTAGCTTTAAATCAATTAGTTTCAGCTAAAC
Transcript ID List	ENST00000555074.1; ENST00000397388.7; ENST00000361265.8; ENST00000262713.7
External Link	RMBase: RNA-editing_site_37094
mod ID: A2ISITE006284		Click to Show/Hide the Full List
mod site	chr14:22972939-22972940:-		[4]
Sequence	GAGTAGAGGACCTAGCTTTAAATCAATTAGTTTCAGCTAAA
Transcript ID List	ENST00000361265.8; ENST00000262713.7; ENST00000397388.7; ENST00000555074.1
External Link	RMBase: RNA-editing_site_37095
mod ID: A2ISITE006285		Click to Show/Hide the Full List
mod site	chr14:22972940-22972941:-		[2]
Sequence	GGAGTAGAGGACCTAGCTTTAAATCAATTAGTTTCAGCTAA
Transcript ID List	ENST00000262713.7; ENST00000361265.8; ENST00000555074.1; ENST00000397388.7
External Link	RMBase: RNA-editing_site_37096
mod ID: A2ISITE006286		Click to Show/Hide the Full List
mod site	chr14:22973048-22973049:-		[2]
Sequence	CCTCCCACCTTGGCCTCCCAAAGTGCTGGGATTATAGGCGT
Transcript ID List	ENST00000555074.1; ENST00000361265.8; ENST00000397388.7; ENST00000262713.7
External Link	RMBase: RNA-editing_site_37097

N1-methyladenosine (m1A)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M1ASITE000032		Click to Show/Hide the Full List
mod site	chr14:22981865-22981866:-		[6]
Sequence	CTCGGCCAGCGACGCGAGCAAGCCGTCCAGCCCCCGGGGCA
Cell/Tissue List	HEK293T
Seq Type List	m1A-seq
Transcript ID List	ENST00000262713.7; ENST00000555074.1; ENST00000361265.8
External Link	RMBase: m1A_site_302

5-methylcytidine (m5C)

In total 4 m6A sequence/site(s) in this target gene
mod ID: M5CSITE000217		Click to Show/Hide the Full List
mod site	chr14:22972383-22972384:-		[7]
Sequence	TATGCATGTGTGGGTGTGTTCATGCACACACACACTCTCTC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000397388.7; ENST00000361265.8; ENST00000262713.7; ENST00000555074.1
External Link	RMBase: m5C_site_12526
mod ID: M5CSITE000218		Click to Show/Hide the Full List
mod site	chr14:22972527-22972528:-		[7]
Sequence	GATTGTACGTGGTTGCTCTTCTCCTTGGCTGGGGGAGGTAA
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000397388.7; ENST00000555074.1; ENST00000262713.7; ENST00000361265.8
External Link	RMBase: m5C_site_12527
mod ID: M5CSITE000219		Click to Show/Hide the Full List
mod site	chr14:22972948-22972949:-		[7]
Sequence	GGATTCCAGGAGTAGAGGACCTAGCTTTAAATCAATTAGTT
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000262713.7; ENST00000361265.8; ENST00000555074.1; ENST00000397388.7
External Link	RMBase: m5C_site_12528
mod ID: M5CSITE000220		Click to Show/Hide the Full List
mod site	chr14:22973489-22973490:-		[7]
Sequence	ACTTGCTCTGCCATGGTTGCCACATGCAGCGGCTCAATGCC
Cell/Tissue List	HeLa
Seq Type List	m5C-RIP-seq; Bisulfite-seq
Transcript ID List	ENST00000262713.7; ENST00000397388.7; ENST00000555074.1; ENST00000361265.8
External Link	RMBase: m5C_site_12529

N6-methyladenosine (m6A)

In total 44 m6A sequence/site(s) in this target gene
mod ID: M6ASITE018911		Click to Show/Hide the Full List
mod site	chr14:22971203-22971204:-		[8]
Sequence	CTATTATTAAATAAGTGAATACAAAGGCCCTATGATGGGAA
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000555074.1; ENST00000262713.7
External Link	RMBase: m6A_site_240093
mod ID: M6ASITE018912		Click to Show/Hide the Full List
mod site	chr14:22971247-22971248:-		[9]
Sequence	GAAACTGAATTACTTCTTGTACAGCTGAGATAGCTTCTTCT
Motif Score	2.856142857
Cell/Tissue List	liver
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000555074.1; ENST00000262713.7
External Link	RMBase: m6A_site_240094
mod ID: M6ASITE018913		Click to Show/Hide the Full List
mod site	chr14:22972094-22972095:-		[10]
Sequence	TTAAAGTTAATGACTTAATGACTAATTTGCCAAAAGCTCAA
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000262713.7; ENST00000361265.8; ENST00000555074.1; ENST00000397388.7
External Link	RMBase: m6A_site_240095
mod ID: M6ASITE018914		Click to Show/Hide the Full List
mod site	chr14:22972574-22972575:-		[8]
Sequence	TCCCTGTTTCTCAGGAACTTACATGGGTCTGGGGAGGCTAG
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000361265.8; ENST00000262713.7; ENST00000555074.1; ENST00000397388.7
External Link	RMBase: m6A_site_240096
mod ID: M6ASITE018915		Click to Show/Hide the Full List
mod site	chr14:22972986-22972987:-		[10]
Sequence	TGTATGATTATGCATGAGTCACGCAATGTTCTGGTCCTGGA
Motif Score	2.021232143
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000262713.7; ENST00000361265.8; ENST00000397388.7; ENST00000555074.1
External Link	RMBase: m6A_site_240097
mod ID: M6ASITE018916		Click to Show/Hide the Full List
mod site	chr14:22973169-22973170:-		[11]
Sequence	AGGGTTCCAGGACTTTCTGAACATCTGATTCTGTATCTTCA
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1B; hNPCs; hESCs; fibroblasts; LCLs; H1299; Huh7; HEK293A-TOA; iSLK; MSC; TIME; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000555074.1; ENST00000361265.8; ENST00000397388.7; ENST00000262713.7
External Link	RMBase: m6A_site_240098
mod ID: M6ASITE018917		Click to Show/Hide the Full List
mod site	chr14:22973178-22973179:-		[11]
Sequence	ACACACAGGAGGGTTCCAGGACTTTCTGAACATCTGATTCT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1B; hNPCs; hESCs; fibroblasts; LCLs; H1299; Huh7; HEK293A-TOA; iSLK; MSC; TIME; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000361265.8; ENST00000262713.7; ENST00000397388.7; ENST00000555074.1
External Link	RMBase: m6A_site_240099
mod ID: M6ASITE018918		Click to Show/Hide the Full List
mod site	chr14:22973198-22973199:-		[8]
Sequence	TGTGCAGTCTGAGCTTAGGCACACACAGGAGGGTTCCAGGA
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000361265.8; ENST00000555074.1; ENST00000397388.7; ENST00000262713.7
External Link	RMBase: m6A_site_240100
mod ID: M6ASITE018919		Click to Show/Hide the Full List
mod site	chr14:22973262-22973263:-		[11]
Sequence	AAATGGATTGTGGAAGAGAAACCTTATATTTACCAGGGTGG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000397388.7; ENST00000262713.7; ENST00000361265.8; ENST00000555074.1
External Link	RMBase: m6A_site_240101
mod ID: M6ASITE018920		Click to Show/Hide the Full List
mod site	chr14:22973303-22973304:-		[11]
Sequence	GAGGACCCCAAGGGCCGGAGACCCAAAGATCATGATATTCC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000361265.8; ENST00000555074.1; ENST00000397388.7; ENST00000262713.7
External Link	RMBase: m6A_site_240102
mod ID: M6ASITE018921		Click to Show/Hide the Full List
mod site	chr14:22973319-22973320:-		[11]
Sequence	AGAAGAGTCCTCTGGGGAGGACCCCAAGGGCCGGAGACCCA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000361265.8; ENST00000397388.7; ENST00000262713.7; ENST00000555074.1
External Link	RMBase: m6A_site_240103
mod ID: M6ASITE018922		Click to Show/Hide the Full List
mod site	chr14:22973404-22973405:-		[12]
Sequence	TGCTGTCACCCTGCAGACAAACTGCTGTGGCCAGTGGGCCC
Motif Score	2.627720238
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000361265.8; ENST00000555074.1; ENST00000397388.7; ENST00000262713.7
External Link	RMBase: m6A_site_240104
mod ID: M6ASITE018923		Click to Show/Hide the Full List
mod site	chr14:22973408-22973409:-		[11]
Sequence	CTGCTGCTGTCACCCTGCAGACAAACTGCTGTGGCCAGTGG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1B; hNPCs; hESCs; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000555074.1; ENST00000262713.7; ENST00000397388.7; ENST00000361265.8
External Link	RMBase: m6A_site_240105
mod ID: M6ASITE018924		Click to Show/Hide the Full List
mod site	chr14:22973452-22973453:-		[12]
Sequence	TGCCCGACAACCCCCTGCCAACTATATCTGAGCTGCAATCA
Motif Score	2.595904762
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000397388.7; ENST00000361265.8; ENST00000262713.7; ENST00000555074.1
External Link	RMBase: m6A_site_240106
mod ID: M6ASITE018925		Click to Show/Hide the Full List
mod site	chr14:22973466-22973467:-		[8]
Sequence	ATGCAGCGGCTCAATGCCCGACAACCCCCTGCCAACTATAT
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000361265.8; ENST00000397388.7; ENST00000555074.1; ENST00000262713.7
External Link	RMBase: m6A_site_240107
mod ID: M6ASITE018926		Click to Show/Hide the Full List
mod site	chr14:22973488-22973489:-		[8]
Sequence	CTTGCTCTGCCATGGTTGCCACATGCAGCGGCTCAATGCCC
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000361265.8; ENST00000555074.1; ENST00000262713.7; ENST00000397388.7
External Link	RMBase: m6A_site_240108
mod ID: M6ASITE018927		Click to Show/Hide the Full List
mod site	chr14:22974080-22974081:-		[11]
Sequence	CGTGAGGGTGATATCCATGGACCGGGATTATCACTTTGAGT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000556731.5; ENST00000553592.5; ENST00000262713.7; ENST00000397388.7; ENST00000555074.1; ENST00000361265.8
External Link	RMBase: m6A_site_240109
mod ID: M6ASITE018928		Click to Show/Hide the Full List
mod site	chr14:22974104-22974105:-		[11]
Sequence	CATGTTTCAGGGCTGTGAGGACATCGTGAGGGTGATATCCA
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000553592.5; ENST00000556731.5; ENST00000262713.7; ENST00000553911.1; ENST00000555074.1; ENST00000397388.7; ENST00000361265.8
External Link	RMBase: m6A_site_240110
mod ID: M6ASITE018929		Click to Show/Hide the Full List
mod site	chr14:22974659-22974660:-		[11]
Sequence	ACCCTAATATCCGGGCCTGGACATGTCTGAAAGCCTAACTG
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000361265.8; ENST00000556731.5; ENST00000555074.1; ENST00000553911.1; ENST00000553592.5; ENST00000555479.1; ENST00000397388.7; ENST00000262713.7
External Link	RMBase: m6A_site_240111
mod ID: M6ASITE018930		Click to Show/Hide the Full List
mod site	chr14:22976843-22976844:-		[13]
Sequence	GAATTTTTGTGCGGGGAAGGACAGACAGCAGTTAGGAGGAA
Motif Score	3.643047619
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000555074.1; ENST00000556731.5; ENST00000397388.7; ENST00000262713.7; ENST00000361265.8
External Link	RMBase: m6A_site_240112
mod ID: M6ASITE018931		Click to Show/Hide the Full List
mod site	chr14:22977509-22977510:-		[13]
Sequence	CAGCTTTCCTAACCCACTGGACAGAGTTGGAAGTAGGGATT
Motif Score	3.643047619
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000262713.7; ENST00000556731.5; ENST00000361265.8; ENST00000555074.1
External Link	RMBase: m6A_site_240113
mod ID: M6ASITE018932		Click to Show/Hide the Full List
mod site	chr14:22977706-22977707:-		[14]
Sequence	CATTCTGATTCCTTTGCTAAACCTTTAATCTCCTATCTCTG
Motif Score	2.185083333
Cell/Tissue List	iSLK; MSC; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000556731.5; ENST00000555074.1; ENST00000262713.7; ENST00000361265.8
External Link	RMBase: m6A_site_240114
mod ID: M6ASITE018933		Click to Show/Hide the Full List
mod site	chr14:22978384-22978385:-		[15]
Sequence	CAATGCCTGCCAGGCCCTGGACAGCCTCTACCACACCCAGT
Motif Score	3.643047619
Cell/Tissue List	HepG2; A549; HeLa; iSLK; MSC; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000555074.1; ENST00000262713.7; ENST00000361265.8
External Link	RMBase: m6A_site_240115
mod ID: M6ASITE018934		Click to Show/Hide the Full List
mod site	chr14:22978629-22978630:-		[15]
Sequence	TCTGTTGAGTAATTAAATAAACAAGAATGGATCTGCTCAGC
Motif Score	2.20572619
Cell/Tissue List	HepG2; A549; HeLa; Huh7; HEK293A-TOA; iSLK; MSC; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000262713.7; ENST00000553736.1; ENST00000555074.1; ENST00000361265.8
External Link	RMBase: m6A_site_240116
mod ID: M6ASITE018935		Click to Show/Hide the Full List
mod site	chr14:22978667-22978668:-		[16]
Sequence	GGTGCTGTGTTAAGCACAAAACAGATGCTCAGAAAATATCT
Motif Score	2.20572619
Cell/Tissue List	A549; Huh7; HEK293A-TOA; iSLK; MSC; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000361265.8; ENST00000262713.7; ENST00000553736.1; ENST00000555074.1; rmsk_4125144
External Link	RMBase: m6A_site_240117
mod ID: M6ASITE018936		Click to Show/Hide the Full List
mod site	chr14:22978725-22978726:-		[11]
Sequence	TAAGCATCTGAATGCCAGGGACCATATCTTCGACTTTCTCC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; Huh7; HEK293A-TOA; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000553736.1; rmsk_4125144; ENST00000361265.8; ENST00000262713.7; ENST00000555074.1
External Link	RMBase: m6A_site_240118
mod ID: M6ASITE018937		Click to Show/Hide the Full List
mod site	chr14:22978747-22978748:-		[11]
Sequence	GTCTTTTCTCCCCAACAGAAACTAAGCATCTGAATGCCAGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; Huh7; HEK293A-TOA; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000361265.8; ENST00000555074.1; rmsk_4125144; ENST00000553736.1; ENST00000262713.7
External Link	RMBase: m6A_site_240119
mod ID: M6ASITE018938		Click to Show/Hide the Full List
mod site	chr14:22978827-22978828:-		[11]
Sequence	CTGCTGCTGAGCACCTGTGGACTGGCATCTTTGACCGTTCA
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; Huh7; HEK293A-TOA; iSLK; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000555074.1; ENST00000553736.1; ENST00000262713.7; ENST00000361265.8
External Link	RMBase: m6A_site_240120
mod ID: M6ASITE018939		Click to Show/Hide the Full List
mod site	chr14:22978908-22978909:-		[11]
Sequence	GCTCGTTTGACTGATGGGAAACTGAAGTCCCAGAGACGATT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; Huh7; HEK293A-TOA; iSLK; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000262713.7; ENST00000555074.1; ENST00000361265.8; ENST00000553736.1
External Link	RMBase: m6A_site_240121
mod ID: M6ASITE018940		Click to Show/Hide the Full List
mod site	chr14:22978931-22978932:-		[11]
Sequence	AGAAATCATTCTATAACTGAACAGCTCGTTTGACTGATGGG
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; Huh7; HEK293A-TOA; iSLK; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000553736.1; ENST00000262713.7; ENST00000555074.1; ENST00000361265.8
External Link	RMBase: m6A_site_240122
mod ID: M6ASITE018941		Click to Show/Hide the Full List
mod site	chr14:22981268-22981269:-		[11]
Sequence	GGAGCCAGAGGCCAGGGAGGACTACTTCGGTGAGTGAGAGA
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000553736.1; ENST00000361265.8; ENST00000262713.7; ENST00000555074.1
External Link	RMBase: m6A_site_240123
mod ID: M6ASITE018942		Click to Show/Hide the Full List
mod site	chr14:22981366-22981367:-		[11]
Sequence	GAAGCCGGAGCCCGCGGAGAACCCTCGGGGATTGAGCCGTC
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; hNPCs; fibroblasts; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000555074.1; ENST00000262713.7; ENST00000553736.1; ENST00000361265.8
External Link	RMBase: m6A_site_240124
mod ID: M6ASITE018943		Click to Show/Hide the Full List
mod site	chr14:22981460-22981461:-		[11]
Sequence	CTCTGTGACCGGCTACGGGGACTGCGCCGTGGGCGCCCGGT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000361265.8; ENST00000553736.1; ENST00000555074.1; ENST00000262713.7
External Link	RMBase: m6A_site_240125
mod ID: M6ASITE018944		Click to Show/Hide the Full List
mod site	chr14:22981631-22981632:-		[11]
Sequence	GGAGCTCCACGCCGCCCTGGACCGATTGTACGCTCAGCGGC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; H1299; Jurkat; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000361265.8; ENST00000262713.7; ENST00000555074.1
External Link	RMBase: m6A_site_240126
mod ID: M6ASITE018945		Click to Show/Hide the Full List
mod site	chr14:22982101-22982102:-		[11]
Sequence	CCCCGAGGAGCTACTGGGGGACCTGGGGATGAGCCGTTGGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; hNPCs; fibroblasts; MM6; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000361265.8; ENST00000262713.7; ENST00000555074.1
External Link	RMBase: m6A_site_240127
mod ID: M6ASITE018946		Click to Show/Hide the Full List
mod site	chr14:22982137-22982138:-		[11]
Sequence	CGCCTAAGTGGGTTGGGGGGACCTAGGAAGTCAGGGCCCCG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; hNPCs; MM6; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000555074.1; ENST00000262713.7; ENST00000361265.8
External Link	RMBase: m6A_site_240128
mod ID: M6ASITE018947		Click to Show/Hide the Full List
mod site	chr14:22982178-22982179:-		[11]
Sequence	GCCGGTCTGGGTCTGACGGGACCCCCGGGCCGGGCAAGGGG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; A549; U2OS; H1A; H1B; hNPCs; MM6; Jurkat; peripheral-blood; GSC-11; HEK293T; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000262713.7; ENST00000361265.8; ENST00000555074.1
External Link	RMBase: m6A_site_240129
mod ID: M6ASITE018948		Click to Show/Hide the Full List
mod site	chr14:22982330-22982331:-		[11]
Sequence	TCCGGCTGCAGGGAAAGAGAACCGGCCGCCGAGACGCCGCA
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1B; H1A; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000361265.8; ENST00000262713.7
External Link	RMBase: m6A_site_240130
mod ID: M6ASITE018949		Click to Show/Hide the Full List
mod site	chr14:22982357-22982358:-		[11]
Sequence	CTCCCCTGTGCCCCTGGGGAACCAGAGTCCGGCTGCAGGGA
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000262713.7
External Link	RMBase: m6A_site_240131
mod ID: M6ASITE018950		Click to Show/Hide the Full List
mod site	chr14:22982491-22982492:-		[11]
Sequence	CTGGACAGCCGCGGCCAGAGACCCTGCTAGCCCCGCTCAGC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; H1299; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000262713.7
External Link	RMBase: m6A_site_240132
mod ID: M6ASITE018951		Click to Show/Hide the Full List
mod site	chr14:22982507-22982508:-		[11]
Sequence	CAGATAGACCTGCGGACTGGACAGCCGCGGCCAGAGACCCT
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; H1299; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000262713.7
External Link	RMBase: m6A_site_240133
mod ID: M6ASITE018952		Click to Show/Hide the Full List
mod site	chr14:22982512-22982513:-		[11]
Sequence	GTGAACAGATAGACCTGCGGACTGGACAGCCGCGGCCAGAG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; H1299; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000262713.7
External Link	RMBase: m6A_site_240134
mod ID: M6ASITE018953		Click to Show/Hide the Full List
mod site	chr14:22982520-22982521:-		[11]
Sequence	GTCGACGCGTGAACAGATAGACCTGCGGACTGGACAGCCGC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; H1299; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000262713.7
External Link	RMBase: m6A_site_240135
mod ID: M6ASITE018954		Click to Show/Hide the Full List
mod site	chr14:22982528-22982529:-		[11]
Sequence	TCGGGCGAGTCGACGCGTGAACAGATAGACCTGCGGACTGG
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; H1299; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000262713.7
External Link	RMBase: m6A_site_240136

Pseudouridine (Pseudo)

In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000042		Click to Show/Hide the Full List
mod site	chr14:22972334-22972335:-		[17]
Sequence	CTCTGTCTCTCTCTCACTCTTTCTTACTCTCTTCTCAGGTC
Transcript ID List	ENST00000555074.1; ENST00000397388.7; ENST00000361265.8; ENST00000262713.7
External Link	RMBase: Pseudo_site_1437

Ref 1	2014 FDA drug approvals. Nat Rev Drug Discov. 2015 Feb;14(2):77-81. doi: 10.1038/nrd4545.
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	Genome-wide identification of human RNA editing sites by parallel DNA capturing and sequencing. Science. 2009 May 29;324(5931):1210-3. doi: 10.1126/science.1170995.
Ref 4	Widespread RNA editing of embedded alu elements in the human transcriptome. Genome Res. 2004 Sep;14(9):1719-25. doi: 10.1101/gr.2855504.
Ref 5	Accurate identification of A-to-I RNA editing in human by transcriptome sequencing. Genome Res. 2012 Jan;22(1):142-50. doi: 10.1101/gr.124107.111. Epub 2011 Sep 29.
Ref 6	The m1A landscape on cytosolic and mitochondrial mRNA at single-base resolution. Nature. 2017 Nov 9;551(7679):251-255. doi: 10.1038/nature24456. Epub 2017 Oct 25.
Ref 7	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 8	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 9	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 10	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 11	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 12	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 13	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 14	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.
Ref 15	Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13.
Ref 16	Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus. Nat Commun. 2019 Oct 9;10(1):4595. doi: 10.1038/s41467-019-12504-y.
Ref 17	Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome. Nat Chem Biol. 2015 Aug;11(8):592-7. doi: 10.1038/nchembio.1836. Epub 2015 Jun 15.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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