m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01454)

Target Name	Apoptosis regulatory protein Siva (SIVA1)
Synonyms	CD27-binding protein; CD27BP Click to Show/Hide
Gene Name	SIVA1
Chromosomal Location	14q32.33
Function	Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. Click to Show/Hide
Gene ID	10572
Uniprot ID	SIVA_HUMAN
HGNC ID	HGNC:17712
KEGG ID	hsa:10572

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Histone modification

m6A Regulator: YTH domain-containing family protein 2 (YTHDF2)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03351		Crosstalk Info
Epigenetic Regulator	Histone acetyltransferase p300 (P300)
Regulated Target	Histone H3 lysine 18 lactylation (H3K18la)
Crosstalk relationship	Histone modification → m6A
Disease	Colorectal cancer	Disease Info
Drug	Fluorouracil	Drug Info

m6A Regulator: Fat mass and obesity-associated protein (FTO)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03449		Crosstalk Info
Epigenetic Regulator	Histone deacetylase 1 (HDAC1)
Regulated Target	Histone H3 lysine 27 acetylation (H3K27ac)
Crosstalk relationship	Histone modification → m6A
Disease	Colorectal cancer	Disease Info
Drug	Fluorouracil	Drug Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01454)

Apoptosis regulatory protein Siva (SIVA1)

N4-acetylcytidine (ac4C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000195		Click to Show/Hide the Full List
mod site	chr14:104755787-104755788:+		[2]
Sequence	TGCTGATTGGACCAGACGGCCGCCTGATCAGGAGCCTTGGG
Cell/Tissue List	H1
Seq Type List	ac4C-seq
Transcript ID List	ENST00000554013.1; ENST00000347067.9; ENST00000535554.4; ENST00000553810.5; ENST00000556431.1; ENST00000556195.2; ENST00000553819.5; ENST00000329967.11
External Link	RMBase: ac4C_site_576

5-methylcytidine (m5C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE000304		Click to Show/Hide the Full List
mod site	chr14:104759187-104759188:+
Sequence	TCCCTGTATCTTCATGTCGTCTTCCTTCTCTGTGTCCTTCT
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000347067.9; ENST00000556431.1; ENST00000556195.2; ENST00000553819.5; ENST00000329967.11
External Link	RMBase: m5C_site_13469

N6-methyladenosine (m6A)

In total 47 m6A sequence/site(s) in this target gene
mod ID: M6ASITE021703		Click to Show/Hide the Full List
mod site	chr14:104753784-104753785:+		[3]
Sequence	CACGGCGGCTTTCTCGGGAGACCAAAGGCAGGCAAGACAGA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; endometrial; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000535554.4; ENST00000347067.9; ENST00000556195.2; ENST00000556431.1; ENST00000553819.5; ENST00000554013.1; ENST00000329967.11; ENST00000553810.5
External Link	RMBase: m6A_site_266060
mod ID: M6ASITE021704		Click to Show/Hide the Full List
mod site	chr14:104753800-104753801:+		[3]
Sequence	GGAGACCAAAGGCAGGCAAGACAGATGTGCCCCGTCTCCCG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; TREX; endometrial; NB4; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000347067.9; ENST00000553810.5; ENST00000535554.4; ENST00000556431.1; ENST00000553819.5; ENST00000556195.2; ENST00000329967.11; ENST00000554013.1
External Link	RMBase: m6A_site_266061
mod ID: M6ASITE021705		Click to Show/Hide the Full List
mod site	chr14:104753846-104753847:+		[4]
Sequence	TCCCCAGCCTAGTTGGGGAGACCAGCAGGAGGAGTCGCCAC
Motif Score	2.876744048
Cell/Tissue List	HepG2; HeLa; HEK293T; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000556431.1; ENST00000556195.2; ENST00000553810.5; ENST00000553819.5; ENST00000329967.11; ENST00000535554.4; ENST00000347067.9; ENST00000554013.1
External Link	RMBase: m6A_site_266062
mod ID: M6ASITE021706		Click to Show/Hide the Full List
mod site	chr14:104755634-104755635:+		[4]
Sequence	TTTATCTTCCCCCAGAGAAGACCAAGCGACTCCTGTTCCTC
Motif Score	2.876744048
Cell/Tissue List	HepG2; HeLa; GSC-11; HEK293T; endometrial; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000553810.5; ENST00000554013.1; ENST00000535554.4; ENST00000329967.11; ENST00000556195.2; ENST00000553819.5; ENST00000347067.9; ENST00000556431.1
External Link	RMBase: m6A_site_266063
mod ID: M6ASITE021707		Click to Show/Hide the Full List
mod site	chr14:104755674-104755675:+		[4]
Sequence	CGGGGCCCAGGCCTACCTGGACCACGTGTGGGATGAAGGCT
Motif Score	3.622404762
Cell/Tissue List	HepG2; HeLa; peripheral-blood; GSC-11; HEK293T; endometrial; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000556431.1; ENST00000553819.5; ENST00000535554.4; ENST00000554013.1; ENST00000329967.11; ENST00000556195.2; ENST00000347067.9; ENST00000553810.5
External Link	RMBase: m6A_site_266064
mod ID: M6ASITE021708		Click to Show/Hide the Full List
mod site	chr14:104755777-104755778:+		[4]
Sequence	CGTGGGCAGATGCTGATTGGACCAGACGGCCGCCTGATCAG
Motif Score	3.622404762
Cell/Tissue List	HepG2; HeLa; peripheral-blood; GSC-11; HEK293T; endometrial; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000554013.1; ENST00000553819.5; ENST00000556195.2; ENST00000556431.1; ENST00000329967.11; ENST00000347067.9; ENST00000535554.4; ENST00000553810.5
External Link	RMBase: m6A_site_266065
mod ID: M6ASITE021709		Click to Show/Hide the Full List
mod site	chr14:104755931-104755932:+		[4]
Sequence	TTCCTCCCTGGGTAAGCAGGACTCTGACCCAGAGCTTGGCC
Motif Score	4.065041667
Cell/Tissue List	HepG2; HeLa; HEK293T; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000556431.1; ENST00000553819.5; ENST00000535554.4; ENST00000556195.2; ENST00000347067.9; ENST00000329967.11; ENST00000553810.5; ENST00000554013.1
External Link	RMBase: m6A_site_266066
mod ID: M6ASITE021710		Click to Show/Hide the Full List
mod site	chr14:104755997-104755998:+		[5]
Sequence	CAGGAGGTCTCACATTCAAGACTGGAAGTTGTTAAACAGCT
Motif Score	3.319380952
Cell/Tissue List	HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000554013.1; ENST00000535554.4; ENST00000556195.2; ENST00000329967.11; ENST00000553810.5; ENST00000556431.1; ENST00000347067.9; ENST00000553819.5
External Link	RMBase: m6A_site_266067
mod ID: M6ASITE021711		Click to Show/Hide the Full List
mod site	chr14:104756012-104756013:+		[6]
Sequence	TCAAGACTGGAAGTTGTTAAACAGCTTCTAAGTACTGGGCC
Motif Score	2.20572619
Cell/Tissue List	HepG2; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329967.11; ENST00000556195.2; ENST00000556431.1; ENST00000553810.5; ENST00000347067.9; ENST00000554013.1; ENST00000553819.5; ENST00000535554.4
External Link	RMBase: m6A_site_266068
mod ID: M6ASITE021712		Click to Show/Hide the Full List
mod site	chr14:104756048-104756049:+		[6]
Sequence	GGGCCAAAAAAGCAGCAGAGACTCCCCGGGTATCCCGTCTG
Motif Score	3.319380952
Cell/Tissue List	HepG2; Huh7; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329967.11; ENST00000535554.4; ENST00000553819.5; ENST00000554013.1; ENST00000553810.5; ENST00000347067.9; ENST00000556195.2; ENST00000556431.1
External Link	RMBase: m6A_site_266069
mod ID: M6ASITE021713		Click to Show/Hide the Full List
mod site	chr14:104756112-104756113:+		[6]
Sequence	ATAGTCCCACAAGGCTGGAAACATGCCAGTCCCATCCCTAT
Motif Score	2.20572619
Cell/Tissue List	HepG2; Huh7; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000347067.9; ENST00000556195.2; ENST00000329967.11; ENST00000553819.5; ENST00000535554.4; ENST00000556431.1; ENST00000554013.1; ENST00000553810.5
External Link	RMBase: m6A_site_266070
mod ID: M6ASITE021714		Click to Show/Hide the Full List
mod site	chr14:104756271-104756272:+		[6]
Sequence	AGGCAGTGGGCCACACTGAGACCCAGATGGGACACATGGAG
Motif Score	2.876744048
Cell/Tissue List	HepG2; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000347067.9; ENST00000556431.1; ENST00000553810.5; ENST00000554013.1; ENST00000553819.5; ENST00000535554.4; ENST00000329967.11; ENST00000556195.2
External Link	RMBase: m6A_site_266071
mod ID: M6ASITE021715		Click to Show/Hide the Full List
mod site	chr14:104756282-104756283:+		[6]
Sequence	CACACTGAGACCCAGATGGGACACATGGAGTTCTGACAAGC
Motif Score	3.643047619
Cell/Tissue List	HepG2; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000554013.1; ENST00000556431.1; ENST00000553810.5; ENST00000535554.4; ENST00000329967.11; ENST00000347067.9; ENST00000556195.2; ENST00000553819.5
External Link	RMBase: m6A_site_266072
mod ID: M6ASITE021716		Click to Show/Hide the Full List
mod site	chr14:104756352-104756353:+		[6]
Sequence	AGCCTCCAGGTAGCAGAGGGACCTGGTAAGGGAAAGAGCAC
Motif Score	3.622404762
Cell/Tissue List	HepG2; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000535554.4; ENST00000556195.2; ENST00000556431.1; ENST00000329967.11; ENST00000553810.5; ENST00000554013.1; ENST00000553819.5; ENST00000347067.9
External Link	RMBase: m6A_site_266073
mod ID: M6ASITE021717		Click to Show/Hide the Full List
mod site	chr14:104756376-104756377:+		[6]
Sequence	GGTAAGGGAAAGAGCACTGAACTTGGAGTCAACTACAGGCA
Motif Score	3.373380952
Cell/Tissue List	HepG2; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000347067.9; ENST00000556195.2; ENST00000554013.1; ENST00000553819.5; rmsk_4276799; ENST00000329967.11; ENST00000535554.4; ENST00000556431.1; ENST00000553810.5
External Link	RMBase: m6A_site_266074
mod ID: M6ASITE021718		Click to Show/Hide the Full List
mod site	chr14:104756556-104756557:+		[3]
Sequence	GTAGCCCGGCAGTCCCGGAAACTCCAGTCTCCTTGCAGCCT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; Huh7; HEK293T; TREX; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329967.11; ENST00000535554.4; ENST00000553819.5; ENST00000553810.5; ENST00000556431.1; ENST00000556195.2; ENST00000347067.9; ENST00000554013.1
External Link	RMBase: m6A_site_266075
mod ID: M6ASITE021719		Click to Show/Hide the Full List
mod site	chr14:104756603-104756604:+		[3]
Sequence	TTGGCGTTTCTTCCTCACAGACCCATCTGGGGTAGCGTCCA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; peripheral-blood; HEK293T; TREX; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000553810.5; ENST00000535554.4; ENST00000554013.1; ENST00000347067.9; ENST00000556431.1; ENST00000329967.11; ENST00000553819.5; ENST00000556195.2
External Link	RMBase: m6A_site_266076
mod ID: M6ASITE021720		Click to Show/Hide the Full List
mod site	chr14:104756849-104756850:+		[6]
Sequence	GTCACCCATGTGGGCCCAGAACACACACGTGTGGCCCCTGA
Motif Score	2.951386905
Cell/Tissue List	HepG2; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329967.11; ENST00000347067.9; ENST00000554013.1; ENST00000556431.1; ENST00000556195.2; ENST00000553819.5; ENST00000553810.5; ENST00000535554.4
External Link	RMBase: m6A_site_266077
mod ID: M6ASITE021721		Click to Show/Hide the Full List
mod site	chr14:104756899-104756900:+		[6]
Sequence	ATCTGGCATTGCCTAACGGGACATGGTGGCAATAGATGCTT
Motif Score	3.643047619
Cell/Tissue List	HepG2; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000553810.5; ENST00000553819.5; ENST00000554013.1; ENST00000329967.11; ENST00000556431.1; ENST00000347067.9; ENST00000556195.2; ENST00000535554.4
External Link	RMBase: m6A_site_266078
mod ID: M6ASITE021722		Click to Show/Hide the Full List
mod site	chr14:104756964-104756965:+		[6]
Sequence	CCTCTCTAAGGGAAAGCTGAACCTCACAGATGACCTGCTCT
Motif Score	2.930744048
Cell/Tissue List	HepG2; MT4; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000535554.4; ENST00000553810.5; ENST00000347067.9; ENST00000556431.1; ENST00000329967.11; ENST00000553819.5; ENST00000556195.2
External Link	RMBase: m6A_site_266079
mod ID: M6ASITE021723		Click to Show/Hide the Full List
mod site	chr14:104757158-104757159:+		[3]
Sequence	TGCGTGCCGTTTGGTTGTAGACCCTCTCAGGCAGGAAGTGG
Motif Score	2.876744048
Cell/Tissue List	HeLa; Huh7; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000329967.11; ENST00000535554.4; ENST00000553819.5; ENST00000556431.1; ENST00000347067.9; ENST00000556195.2; ENST00000553810.5
External Link	RMBase: m6A_site_266080
mod ID: M6ASITE021724		Click to Show/Hide the Full List
mod site	chr14:104757302-104757303:+		[3]
Sequence	CACCTGGTGGATGGGAGTGGACAGTGTGGAGCCTGTTTGCC
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000347067.9; ENST00000553819.5; ENST00000535554.4; ENST00000553810.5; ENST00000329967.11; ENST00000556431.1; ENST00000556195.2
External Link	RMBase: m6A_site_266081
mod ID: M6ASITE021725		Click to Show/Hide the Full List
mod site	chr14:104757852-104757853:+		[3]
Sequence	CTGCACACCATCCTTGAGGGACTCCCTTGCGCCCATTTCCT
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000329967.11; ENST00000347067.9; ENST00000556195.2; ENST00000553819.5; ENST00000556431.1
External Link	RMBase: m6A_site_266082
mod ID: M6ASITE021726		Click to Show/Hide the Full List
mod site	chr14:104758328-104758329:+		[7]
Sequence	ACCCACAATACTACTGGCAAACTCTGCAAACCAAGTGGCAA
Motif Score	2.627720238
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000347067.9; ENST00000556195.2; ENST00000556431.1; ENST00000329967.11; ENST00000553819.5
External Link	RMBase: m6A_site_266083
mod ID: M6ASITE021727		Click to Show/Hide the Full List
mod site	chr14:104758337-104758338:+		[7]
Sequence	ACTACTGGCAAACTCTGCAAACCAAGTGGCAAGCAGTTCTG
Motif Score	2.185083333
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000553819.5; ENST00000329967.11; ENST00000556195.2; ENST00000347067.9; ENST00000556431.1
External Link	RMBase: m6A_site_266084
mod ID: M6ASITE021728		Click to Show/Hide the Full List
mod site	chr14:104758993-104758994:+		[7]
Sequence	TGCTGTAACTGAGTTCGCAGACCCAGTGGCATAGACAGCAA
Motif Score	2.876744048
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000556431.1; ENST00000556195.2; ENST00000329967.11; ENST00000553819.5; ENST00000347067.9
External Link	RMBase: m6A_site_266085
mod ID: M6ASITE021729		Click to Show/Hide the Full List
mod site	chr14:104759007-104759008:+		[7]
Sequence	TCGCAGACCCAGTGGCATAGACAGCAAAGAGGTACTGCCAC
Motif Score	2.897386905
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000553819.5; ENST00000556195.2; ENST00000556431.1; ENST00000347067.9; ENST00000329967.11
External Link	RMBase: m6A_site_266086
mod ID: M6ASITE021730		Click to Show/Hide the Full List
mod site	chr14:104759040-104759041:+		[7]
Sequence	ACTGCCACGTGGCTTTGGAGACCAGAAGTCTGAGAGGAAGG
Motif Score	2.876744048
Cell/Tissue List	TREX
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000556431.1; ENST00000556195.2; ENST00000347067.9; ENST00000329967.11; ENST00000553819.5
External Link	RMBase: m6A_site_266087
mod ID: M6ASITE021731		Click to Show/Hide the Full List
mod site	chr14:104759100-104759101:+		[3]
Sequence	TTCTGAGGCTGCAATGGAAAACCTGTCCTGGCCTCTCTCCT
Motif Score	2.185083333
Cell/Tissue List	HeLa; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000556195.2; ENST00000556431.1; ENST00000329967.11; ENST00000553819.5; ENST00000347067.9
External Link	RMBase: m6A_site_266088
mod ID: M6ASITE021732		Click to Show/Hide the Full List
mod site	chr14:104759155-104759156:+		[3]
Sequence	ATCTTTGGTGTTCCCTGTAGACAGCTGCCCCCTCCCTGTAT
Motif Score	2.897386905
Cell/Tissue List	HeLa; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000556195.2; ENST00000553819.5; ENST00000347067.9; ENST00000329967.11; ENST00000556431.1
External Link	RMBase: m6A_site_266089
mod ID: M6ASITE021733		Click to Show/Hide the Full List
mod site	chr14:104759435-104759436:+		[8]
Sequence	ACGCTGTCGCAGCTGCAGTGACATGTACGAGAAAGTGCTGT
Motif Score	2.859755952
Cell/Tissue List	liver; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000556431.1; ENST00000347067.9; ENST00000553819.5; ENST00000556195.2; ENST00000329967.11
External Link	RMBase: m6A_site_266090
mod ID: M6ASITE021734		Click to Show/Hide the Full List
mod site	chr14:104759441-104759442:+		[9]
Sequence	TCGCAGCTGCAGTGACATGTACGAGAAAGTGCTGTGCACCA
Motif Score	2.830077381
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000556195.2; ENST00000556431.1; ENST00000347067.9; ENST00000329967.11; ENST00000553819.5
External Link	RMBase: m6A_site_266091
mod ID: M6ASITE021735		Click to Show/Hide the Full List
mod site	chr14:104759479-104759480:+		[3]
Sequence	CCAGCTGTGCCATGTTCGAGACCTGAGGCTGGCTCAAGCCG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T
Seq Type List	m6A-seq
Transcript ID List	ENST00000329967.11; ENST00000347067.9; ENST00000556195.2; ENST00000556431.1; ENST00000553819.5
External Link	RMBase: m6A_site_266092
mod ID: M6ASITE021736		Click to Show/Hide the Full List
mod site	chr14:104759562-104759563:+		[8]
Sequence	TGGACGAGCGCTCGGTGTTCACACTGAACTGTGGGGTCGAC
Motif Score	2.047297619
Cell/Tissue List	kidney; liver; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	ENST00000329967.11; ENST00000556195.2; ENST00000556431.1; ENST00000347067.9; ENST00000553819.5
External Link	RMBase: m6A_site_266093
mod ID: M6ASITE021737		Click to Show/Hide the Full List
mod site	chr14:104759569-104759570:+		[3]
Sequence	GCGCTCGGTGTTCACACTGAACTGTGGGGTCGACGGGAGGG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; A549; H1299; HEK293T; AML
Seq Type List	m6A-seq; m6A-CLIP/IP; miCLIP
Transcript ID List	ENST00000329967.11; ENST00000556431.1; ENST00000347067.9; ENST00000556195.2; ENST00000553819.5
External Link	RMBase: m6A_site_266094
mod ID: M6ASITE021738		Click to Show/Hide the Full List
mod site	chr14:104759581-104759582:+		[9]
Sequence	CACACTGAACTGTGGGGTCGACGGGAGGGGTGCCTTTTACA
Motif Score	2.839505952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000556431.1; ENST00000553819.5; ENST00000347067.9; ENST00000329967.11
External Link	RMBase: m6A_site_266095
mod ID: M6ASITE021739		Click to Show/Hide the Full List
mod site	chr14:104759599-104759600:+		[9]
Sequence	CGACGGGAGGGGTGCCTTTTACATGTTCTATTTTGTATCCT
Motif Score	2.07285119
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000329967.11; ENST00000347067.9; ENST00000553819.5; ENST00000556431.1
External Link	RMBase: m6A_site_266096
mod ID: M6ASITE021740		Click to Show/Hide the Full List
mod site	chr14:104759624-104759625:+		[9]
Sequence	TTCTATTTTGTATCCTAATGACAGAATGAATAAACCTCTTT
Motif Score	2.859755952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000556431.1; ENST00000553819.5; ENST00000329967.11; ENST00000347067.9
External Link	RMBase: m6A_site_266097
mod ID: M6ASITE021741		Click to Show/Hide the Full List
mod site	chr14:104759637-104759638:+		[3]
Sequence	CCTAATGACAGAATGAATAAACCTCTTTATATTTGCACAAG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; A549; H1299
Seq Type List	m6A-seq
Transcript ID List	ENST00000553819.5; ENST00000347067.9; ENST00000556431.1; ENST00000329967.11
External Link	RMBase: m6A_site_266098
mod ID: M6ASITE021742		Click to Show/Hide the Full List
mod site	chr14:104766832-104766833:+		[3]
Sequence	ATGATGTGGGCATGTGAGAAACAAACTCACCCATCCACACC
Motif Score	2.20572619
Cell/Tissue List	HeLa; A549; H1299
Seq Type List	m6A-seq
Transcript ID List	ENST00000553819.5
External Link	RMBase: m6A_site_266099
mod ID: M6ASITE021743		Click to Show/Hide the Full List
mod site	chr14:104766880-104766881:+		[10]
Sequence	TGGACTCAGAGACCTCAGAGACCGGAGAACAGCAAAAGTGA
Motif Score	2.876744048
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000553819.5
External Link	RMBase: m6A_site_266100
mod ID: M6ASITE021744		Click to Show/Hide the Full List
mod site	chr14:104766888-104766889:+		[10]
Sequence	GAGACCTCAGAGACCGGAGAACAGCAAAAGTGAGACTTTTA
Motif Score	2.951386905
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000553819.5
External Link	RMBase: m6A_site_266101
mod ID: M6ASITE021745		Click to Show/Hide the Full List
mod site	chr14:104767924-104767925:+		[10]
Sequence	AATCCCAACGTTTTGGGAGGACAAGGCAGGAGGATCACTTG
Motif Score	3.643047619
Cell/Tissue List	MT4; Huh7
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_4276825; ENST00000553819.5
External Link	RMBase: m6A_site_266102
mod ID: M6ASITE021746		Click to Show/Hide the Full List
mod site	chr14:104767961-104767962:+		[10]
Sequence	CTTGAGGCCCGGAGTTCAAGACCGGCCTGAACAACATAGCG
Motif Score	2.876744048
Cell/Tissue List	MT4; Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000553819.5; rmsk_4276825
External Link	RMBase: m6A_site_266103
mod ID: M6ASITE021747		Click to Show/Hide the Full List
mod site	chr14:104767971-104767972:+		[10]
Sequence	GGAGTTCAAGACCGGCCTGAACAACATAGCGAGACCCTATC
Motif Score	2.951386905
Cell/Tissue List	MT4; Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000553819.5; rmsk_4276825
External Link	RMBase: m6A_site_266104
mod ID: M6ASITE021748		Click to Show/Hide the Full List
mod site	chr14:104767984-104767985:+		[10]
Sequence	GGCCTGAACAACATAGCGAGACCCTATCTCTACCATAAAAA
Motif Score	2.876744048
Cell/Tissue List	MT4; Huh7
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_4276825; ENST00000553819.5
External Link	RMBase: m6A_site_266105
mod ID: M6ASITE021749		Click to Show/Hide the Full List
mod site	chr14:104768398-104768399:+		[10]
Sequence	TTGGCTCCCACAGACCCAGAACATCCTCGCCAGCCTGTGCT
Motif Score	2.951386905
Cell/Tissue List	MT4; Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000553819.5
External Link	RMBase: m6A_site_266106

N7-methylguanosine (m7G)

In total 1 m6A sequence/site(s) in this target gene
mod ID: m7GSITE000029		Click to Show/Hide the Full List
mod site	chr14:104753149-104753150:+		[11]
Sequence	AGCTGTGACGTCACGGCGTCGTTGGTAAGGGGCTGGCGGCC
Cell/Tissue List	A549; HeLa; HepG2
Seq Type List	BoRed-seq&m7G-RIP-seq; m7G-seq
Transcript ID List	ENST00000535554.4; ENST00000329967.11
External Link	RMBase: m7G_site_263

2'-O-Methylation (2'-O-Me)

In total 1 m6A sequence/site(s) in this target gene
mod ID: 2OMSITE000094		Click to Show/Hide the Full List
mod site	chr14:104759573-104759574:+		[12]
Sequence	TCGGTGTTCACACTGAACTGTGGGGTCGACGGGAGGGGTGC
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000329967.11; ENST00000556431.1; ENST00000556195.2; ENST00000553819.5; ENST00000347067.9
External Link	RMBase: Nm_site_1823

Ref 1	US patent application no. 6,274,627, Conjugates of dithiocarbamate disulfides with pharmacologically active agents and uses therefor.
Ref 2	NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells. Nucleic Acids Res. 2023 Sep 8;51(16):8514-8531. doi: 10.1093/nar/gkad628.
Ref 3	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 4	Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13.
Ref 5	[Action myoclonias and paranoid alternative psychosis in progressive myoclonic epilepsy (late form of the Lafora type)]. Nervenarzt. 1986 Apr;57(4):233-7.
Ref 6	Efficacy of MEK inhibition in patients with histiocytic neoplasms. Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.
Ref 7	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.
Ref 8	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 9	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 10	Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells. Nat Microbiol. 2016 Feb 22;1:16011. doi: 10.1038/nmicrobiol.2016.11.
Ref 11	METTL1 Promotes let-7 MicroRNA Processing via m7G Methylation. Mol Cell. 2019 Jun 20;74(6):1278-1290.e9. doi: 10.1016/j.molcel.2019.03.040. Epub 2019 Apr 25.
Ref 12	Nm-seq maps 2'-O-methylation sites in human mRNA with base precision. Nat Methods. 2017 Jul;14(7):695-698. doi: 10.1038/nmeth.4294. Epub 2017 May 15.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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