m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01412)

Target Name	Growth factor receptor-bound protein 2 (GRB2)
Synonyms	Adapter protein GRB2; Protein Ash; SH2/SH3 adapter GRB2 Click to Show/Hide
Gene Name	GRB2
Chromosomal Location	17q25.1
Family	GRB2/sem-5/DRK family
Function	Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. Click to Show/Hide
Gene ID	2885
Uniprot ID	GRB2_HUMAN
HGNC ID	HGNC:4566
KEGG ID	hsa:2885

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Non-coding RNA

m6A Regulator: Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05365		Crosstalk Info
Epigenetic Regulator	Long intergenic non-protein coding RNA 1705 (LINC01705)
Regulated Target	Heterogeneous nuclear ribonucleoprotein C (HNRNPC)
Crosstalk relationship	ncRNA → m6A
Disease	Lung cancer	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01412)

Growth factor receptor-bound protein 2 (GRB2)

Adenosine-to-Inosine editing (A-to-I)

In total 13 m6A sequence/site(s) in this target gene
mod ID: A2ISITE008458		Click to Show/Hide the Full List
mod site	chr17:75322736-75322737:-		[2]
Sequence	TGTGACAGACCCTGTGAGCTAGTACCAGCCAGCCACGCTGT
Transcript ID List	ENST00000392562.5; ENST00000462266.1; ENST00000582582.1; ENST00000648046.1; ENST00000392564.5; ENST00000316804.10; ENST00000316615.9; ENST00000392563.5; ENST00000578961.5
External Link	RMBase: RNA-editing_site_60723
mod ID: A2ISITE008459		Click to Show/Hide the Full List
mod site	chr17:75322929-75322930:-		[3]
Sequence	AGACGGGGTTTCACTGTGTTAGCCATGGTGGTCTCGATATC
Transcript ID List	ENST00000316615.9; ENST00000392564.5; ENST00000462266.1; ENST00000578961.5; ENST00000316804.10; ENST00000582582.1; ENST00000648046.1; ENST00000392563.5; ENST00000392562.5
External Link	RMBase: RNA-editing_site_60724
mod ID: A2ISITE008460		Click to Show/Hide the Full List
mod site	chr17:75323973-75323974:-		[2]
Sequence	ACTAAAAAAATACAAAAATTAGCCAGGCGTGGTGGCACATG
Transcript ID List	rmsk_4765827; ENST00000392564.5; ENST00000316615.9; ENST00000582582.1; ENST00000392563.5; ENST00000392562.5; ENST00000316804.10; ENST00000462266.1; ENST00000578961.5; ENST00000648046.1
External Link	RMBase: RNA-editing_site_60725
mod ID: A2ISITE008461		Click to Show/Hide the Full List
mod site	chr17:75324548-75324549:-		[2]
Sequence	CTTTAGCCTGGGCGAAGAGCAAAACTCTGTCTCCAAAAAAA
Transcript ID List	ENST00000392562.5; rmsk_4765829; ENST00000316615.9; ENST00000582582.1; ENST00000578961.5; ENST00000392563.5; ENST00000648046.1; ENST00000392564.5; ENST00000316804.10; ENST00000462266.1
External Link	RMBase: RNA-editing_site_60726
mod ID: A2ISITE008462		Click to Show/Hide the Full List
mod site	chr17:75324953-75324954:-		[4]
Sequence	CCCTCCGAGTACCTGGGATTACAGGTGCCTGACACCACGCC
Transcript ID List	ENST00000392563.5; ENST00000392564.5; ENST00000392562.5; ENST00000462266.1; ENST00000578961.5; ENST00000648046.1; ENST00000316804.10; ENST00000316615.9; ENST00000582582.1
External Link	RMBase: RNA-editing_site_60727
mod ID: A2ISITE008463		Click to Show/Hide the Full List
mod site	chr17:75337012-75337013:-		[2]
Sequence	CAGCATGATGGCTCACGCCTATAATCCCAGCACTTTGAGAG
Transcript ID List	ENST00000392564.5; rmsk_4765860; ENST00000582582.1; ENST00000316804.10; ENST00000578961.5; ENST00000316615.9; ENST00000648046.1; ENST00000392563.5; ENST00000392562.5
External Link	RMBase: RNA-editing_site_60728
mod ID: A2ISITE008464		Click to Show/Hide the Full List
mod site	chr17:75351430-75351431:-		[4]
Sequence	GTCTTGATCTCCTGGGTTCAAGTGATTCTTCCGCCTCAGCC
Transcript ID List	ENST00000392562.5; ENST00000648046.1; ENST00000578961.5; ENST00000316804.10; ENST00000582582.1; ENST00000316615.9; ENST00000392564.5; ENST00000392563.5
External Link	RMBase: RNA-editing_site_60729
mod ID: A2ISITE008465		Click to Show/Hide the Full List
mod site	chr17:75351531-75351532:-		[4]
Sequence	GTCTCAGAGTAGCTGGGACTACAGCCGCACACCACTATACC
Transcript ID List	ENST00000316804.10; ENST00000392563.5; ENST00000582582.1; ENST00000578961.5; ENST00000316615.9; ENST00000392562.5; ENST00000648046.1; ENST00000392564.5
External Link	RMBase: RNA-editing_site_60730
mod ID: A2ISITE008466		Click to Show/Hide the Full List
mod site	chr17:75355906-75355907:-		[3]
Sequence	ACTCGGGAGGCGAAGGTTGCAGTAAGCCGAGATCACGCCAC
Transcript ID List	ENST00000392562.5; ENST00000316804.10; ENST00000582582.1; ENST00000392564.5; ENST00000392563.5; rmsk_4765911; ENST00000578961.5; ENST00000316615.9; ENST00000648046.1
External Link	RMBase: RNA-editing_site_60731
mod ID: A2ISITE008467		Click to Show/Hide the Full List
mod site	chr17:75356399-75356400:-		[3]
Sequence	TCCTCCTGCCTCAGCCTCCCAAGTAGCTGGGACCACAGGTA
Transcript ID List	ENST00000316615.9; ENST00000392564.5; ENST00000392562.5; ENST00000578961.5; ENST00000582582.1; ENST00000648046.1; ENST00000316804.10; ENST00000392563.5
External Link	RMBase: RNA-editing_site_60732
mod ID: A2ISITE008468		Click to Show/Hide the Full List
mod site	chr17:75374066-75374067:-		[2]
Sequence	CACGGTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGGCT
Transcript ID List	ENST00000582582.1; ENST00000316615.9; ENST00000578961.5; ENST00000648046.1; ENST00000392563.5; ENST00000316804.10; ENST00000392564.5; ENST00000392562.5; rmsk_4765951
External Link	RMBase: RNA-editing_site_60733
mod ID: A2ISITE008469		Click to Show/Hide the Full List
mod site	chr17:75375043-75375044:-		[3]
Sequence	AATTAGCCAATCGTGGTGGCACACATCTGCAGTCCCAGCTA
Transcript ID List	ENST00000392564.5; ENST00000316804.10; ENST00000392563.5; ENST00000582582.1; ENST00000578961.5; rmsk_4765956; ENST00000392562.5; ENST00000648046.1; ENST00000316615.9
External Link	RMBase: RNA-editing_site_60734
mod ID: A2ISITE008470		Click to Show/Hide the Full List
mod site	chr17:75376941-75376942:-		[4]
Sequence	CATGGCTCAGTACAGCCCCAACATTCCAGGCTCAGTTGATC
Transcript ID List	ENST00000316804.10; ENST00000582582.1; ENST00000392564.5; ENST00000392563.5; ENST00000648046.1; ENST00000392562.5; ENST00000578961.5; ENST00000316615.9
External Link	RMBase: RNA-editing_site_60735

5-methylcytidine (m5C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE001277		Click to Show/Hide the Full List
mod site	chr17:75318970-75318971:-		[5]
Sequence	GAAGCCTGTCCTCACCGTCTCGGGGGTTGTGGCCCCCGCCC
Cell/Tissue List	frontalcortex; HEK293T; lung; spleen; testis; HeLa; T24
Seq Type List	Bisulfite-seq; m5C-RIP-seq
Transcript ID List	ENST00000316615.9; ENST00000392563.5; ENST00000392564.5; ENST00000392562.5; ENST00000581959.1; ENST00000316804.10
External Link	RMBase: m5C_site_19880

N6-methyladenosine (m6A)

In total 53 m6A sequence/site(s) in this target gene
mod ID: M6ASITE035232		Click to Show/Hide the Full List
mod site	chr17:75318091-75318092:-		[6]
Sequence	ATTAACTGTGAATAATAAATACACAATGAATTCTTCACTTG
Motif Score	2.110482143
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000392563.5; ENST00000392564.5; ENST00000392562.5; ENST00000316615.9; ENST00000316804.10; ENST00000581959.1
External Link	RMBase: m6A_site_381804
mod ID: M6ASITE035233		Click to Show/Hide the Full List
mod site	chr17:75318140-75318141:-		[6]
Sequence	CCTATGTACTTAATCCTTTAACTCTGCGGATAGCATTTGGT
Motif Score	2.590089286
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000316804.10; ENST00000392564.5; ENST00000581959.1; ENST00000316615.9; ENST00000392563.5; ENST00000392562.5
External Link	RMBase: m6A_site_381805
mod ID: M6ASITE035234		Click to Show/Hide the Full List
mod site	chr17:75318212-75318213:-		[7]
Sequence	ATATCATGAAGCCTTGCTGAACTAAGTTTTGTGTGTATATA
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000316615.9; ENST00000392563.5; ENST00000392562.5; ENST00000392564.5; ENST00000581959.1; ENST00000316804.10
External Link	RMBase: m6A_site_381806
mod ID: M6ASITE035235		Click to Show/Hide the Full List
mod site	chr17:75318264-75318265:-		[7]
Sequence	ATCTGGCATTCTACACCTGGACCATTTGATTGTTTTATTTT
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000316804.10; ENST00000316615.9; ENST00000392562.5; ENST00000392563.5; ENST00000581959.1; ENST00000392564.5
External Link	RMBase: m6A_site_381807
mod ID: M6ASITE035236		Click to Show/Hide the Full List
mod site	chr17:75318272-75318273:-		[8]
Sequence	TAAAAGGAATCTGGCATTCTACACCTGGACCATTTGATTGT
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000392562.5; ENST00000392564.5; ENST00000581959.1; ENST00000316615.9; ENST00000392563.5; ENST00000316804.10
External Link	RMBase: m6A_site_381808
mod ID: M6ASITE035237		Click to Show/Hide the Full List
mod site	chr17:75318408-75318409:-		[7]
Sequence	CCCTCCGACTCCAGATATGAACAGGGCCCAGGCCTGGAGCG
Motif Score	2.951386905
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000581959.1; ENST00000392562.5; ENST00000392564.5; ENST00000316615.9; ENST00000392563.5; ENST00000316804.10
External Link	RMBase: m6A_site_381809
mod ID: M6ASITE035238		Click to Show/Hide the Full List
mod site	chr17:75318500-75318501:-		[7]
Sequence	CTTCCCACGACAAAAACAAGACTGCCTCCCTCTCTTCCGGG
Motif Score	3.319380952
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000316615.9; ENST00000316804.10; ENST00000392563.5; ENST00000581959.1; ENST00000392562.5; ENST00000392564.5
External Link	RMBase: m6A_site_381810
mod ID: M6ASITE035239		Click to Show/Hide the Full List
mod site	chr17:75318505-75318506:-		[7]
Sequence	AACCCCTTCCCACGACAAAAACAAGACTGCCTCCCTCTCTT
Motif Score	2.20572619
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000316615.9; ENST00000316804.10; ENST00000392563.5; ENST00000392562.5; ENST00000392564.5; ENST00000581959.1
External Link	RMBase: m6A_site_381811
mod ID: M6ASITE035240		Click to Show/Hide the Full List
mod site	chr17:75318524-75318525:-		[7]
Sequence	TAATCTTTTTCTCCACCCAAACCCCTTCCCACGACAAAAAC
Motif Score	2.185083333
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000316804.10; ENST00000316615.9; ENST00000392564.5; ENST00000392562.5; ENST00000392563.5; ENST00000581959.1
External Link	RMBase: m6A_site_381812
mod ID: M6ASITE035241		Click to Show/Hide the Full List
mod site	chr17:75318591-75318592:-		[7]
Sequence	AAGACCAAGGCCTCGGCAGAACTCTCTGTCTTCTCTCCACT
Motif Score	3.373380952
Cell/Tissue List	HeLa; CD34; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000316804.10; ENST00000581959.1; ENST00000392564.5; ENST00000316615.9; ENST00000392563.5; ENST00000392562.5
External Link	RMBase: m6A_site_381813
mod ID: M6ASITE035242		Click to Show/Hide the Full List
mod site	chr17:75318608-75318609:-		[7]
Sequence	AAGATTGGAAAGACAGGAAGACCAAGGCCTCGGCAGAACTC
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000316615.9; ENST00000392562.5; ENST00000392563.5; ENST00000581959.1; ENST00000316804.10; ENST00000392564.5
External Link	RMBase: m6A_site_381814
mod ID: M6ASITE035243		Click to Show/Hide the Full List
mod site	chr17:75318616-75318617:-		[7]
Sequence	GGGAAGGCAAGATTGGAAAGACAGGAAGACCAAGGCCTCGG
Motif Score	2.897386905
Cell/Tissue List	HeLa; CD34; brain; liver; Huh7
Seq Type List	m6A-seq; m6A-REF-seq; MeRIP-seq
Transcript ID List	ENST00000581959.1; ENST00000316615.9; ENST00000392564.5; ENST00000392563.5; ENST00000392562.5; ENST00000316804.10
External Link	RMBase: m6A_site_381815
mod ID: M6ASITE035244		Click to Show/Hide the Full List
mod site	chr17:75318836-75318837:-		[8]
Sequence	CACTATTCCTATGCTGGGGTACACAGTGAGAGTACTCACTT
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000392563.5; ENST00000392562.5; ENST00000316804.10; ENST00000581959.1; ENST00000316615.9; ENST00000392564.5
External Link	RMBase: m6A_site_381816
mod ID: M6ASITE035245		Click to Show/Hide the Full List
mod site	chr17:75318912-75318913:-		[8]
Sequence	CTGGAACCAGCAAGTCCCAGACAAGGAGAGCGGAGGAGGAA
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000316804.10; ENST00000316615.9; ENST00000392564.5; ENST00000581959.1; ENST00000392563.5; ENST00000392562.5
External Link	RMBase: m6A_site_381817
mod ID: M6ASITE035246		Click to Show/Hide the Full List
mod site	chr17:75319198-75319199:-		[8]
Sequence	GCCAGGGTAGAGCAAAGGAGACAAAGCAGGAGTGGAAGGTG
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000392562.5; ENST00000316804.10; ENST00000392564.5; ENST00000316615.9; ENST00000392563.5; ENST00000581959.1
External Link	RMBase: m6A_site_381818
mod ID: M6ASITE035247		Click to Show/Hide the Full List
mod site	chr17:75319253-75319254:-		[6]
Sequence	TTTCAGCCAATTTGTCTCCTACTCTGTGTAAATATTTTTCC
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000316804.10; ENST00000316615.9; ENST00000392564.5; ENST00000581959.1; ENST00000392563.5; ENST00000392562.5
External Link	RMBase: m6A_site_381819
mod ID: M6ASITE035248		Click to Show/Hide the Full List
mod site	chr17:75319511-75319512:-		[7]
Sequence	TGGAGGTTGAGTGAGCCGGGACCGTGCCATTGTACTCCAGC
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000392564.5; ENST00000648046.1; ENST00000392563.5; ENST00000316615.9; ENST00000581959.1; ENST00000392562.5; rmsk_4765823; ENST00000316804.10
External Link	RMBase: m6A_site_381820
mod ID: M6ASITE035249		Click to Show/Hide the Full List
mod site	chr17:75319676-75319677:-		[9]
Sequence	GAGGCCAAGGTGGGCGGATCACAAGGTCAGGAGTTCGAGAC
Motif Score	2.047297619
Cell/Tissue List	kidney; hESC-HEK293T
Seq Type List	m6A-REF-seq; MAZTER-seq
Transcript ID List	rmsk_4765823; ENST00000392564.5; ENST00000392562.5; ENST00000316615.9; ENST00000316804.10; ENST00000581959.1; ENST00000392563.5; ENST00000648046.1
External Link	RMBase: m6A_site_381821
mod ID: M6ASITE035250		Click to Show/Hide the Full List
mod site	chr17:75319803-75319804:-		[6]
Sequence	AGTGTATTTTGTCCAAGTTCACAGTAGAGTAGGGTAGAAGG
Motif Score	2.047297619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000316804.10; ENST00000392564.5; ENST00000392562.5; ENST00000648046.1; ENST00000581959.1; ENST00000392563.5; ENST00000316615.9
External Link	RMBase: m6A_site_381822
mod ID: M6ASITE035251		Click to Show/Hide the Full List
mod site	chr17:75319919-75319920:-		[8]
Sequence	TGTGTTCTTCGTATATACACACAAAAAGGAGCGGGCAGGGC
Motif Score	2.084928571
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000392562.5; ENST00000648046.1; ENST00000392564.5; ENST00000392563.5; ENST00000316615.9; ENST00000581959.1; ENST00000316804.10
External Link	RMBase: m6A_site_381823
mod ID: M6ASITE035252		Click to Show/Hide the Full List
mod site	chr17:75319962-75319963:-		[6]
Sequence	TGTCTGTTTTAGTTGGAATGACTGAAAGAAGAACAGCTGTT
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000648046.1; ENST00000316804.10; ENST00000392563.5; ENST00000392562.5; ENST00000581959.1; ENST00000392564.5; ENST00000316615.9
External Link	RMBase: m6A_site_381824
mod ID: M6ASITE035253		Click to Show/Hide the Full List
mod site	chr17:75320014-75320015:-		[7]
Sequence	CCAATAATAAAAAACAAGAAACCAAGTGGGCTGGTATTCTC
Motif Score	2.185083333
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000581959.1; ENST00000392562.5; ENST00000316615.9; ENST00000316804.10; ENST00000392563.5; ENST00000648046.1; ENST00000392564.5
External Link	RMBase: m6A_site_381825
mod ID: M6ASITE035254		Click to Show/Hide the Full List
mod site	chr17:75320021-75320022:-		[7]
Sequence	GCTGACGCCAATAATAAAAAACAAGAAACCAAGTGGGCTGG
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; Huh7
Seq Type List	m6A-seq; DART-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000316804.10; ENST00000581959.1; ENST00000392563.5; ENST00000316615.9; ENST00000648046.1; ENST00000392564.5; ENST00000392562.5
External Link	RMBase: m6A_site_381826
mod ID: M6ASITE035255		Click to Show/Hide the Full List
mod site	chr17:75320066-75320067:-		[6]
Sequence	CTTCTGTCCATCAGTGCATGACGTTTAAGGCCACGTATAGT
Motif Score	2.833690476
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000392562.5; ENST00000392563.5; ENST00000316615.9; ENST00000581959.1; ENST00000648046.1; ENST00000392564.5; ENST00000316804.10
External Link	RMBase: m6A_site_381827
mod ID: M6ASITE035256		Click to Show/Hide the Full List
mod site	chr17:75320146-75320147:-		[8]
Sequence	AATTAAGAAGAGTTTTTATTACAAATTTTCACTGCTGCTCC
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000581959.1; ENST00000648046.1; ENST00000316804.10; ENST00000392563.5; ENST00000392562.5; ENST00000316615.9; ENST00000392564.5
External Link	RMBase: m6A_site_381828
mod ID: M6ASITE035257		Click to Show/Hide the Full List
mod site	chr17:75320177-75320178:-		[7]
Sequence	TTGGATTTAAAAATGCCAAAACTTACCTATAAATTAAGAAG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T; HepG2; hESCs; fibroblasts; A549; LCLs; H1299; Huh7; iSLK; MSC; TREX
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000648046.1; ENST00000316804.10; ENST00000316615.9; ENST00000392563.5; ENST00000581959.1; ENST00000392564.5; ENST00000392562.5
External Link	RMBase: m6A_site_381829
mod ID: M6ASITE035258		Click to Show/Hide the Full List
mod site	chr17:75320220-75320221:-		[7]
Sequence	ACCCTCTCACTTTGGTTGGAACTTTAGGGGGTGGGAGGGGG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; hNPCs; hESCs; fibroblasts; A549; LCLs; CD8T; H1299; Huh7; iSLK; MSC; TREX
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000392564.5; ENST00000648046.1; ENST00000392563.5; ENST00000316615.9; ENST00000316804.10; ENST00000581959.1; ENST00000392562.5
External Link	RMBase: m6A_site_381830
mod ID: M6ASITE035259		Click to Show/Hide the Full List
mod site	chr17:75320263-75320264:-		[7]
Sequence	AGCCTGTGAGGGAGTGCAGAACACCTGGCCGGGTCACCCTG
Motif Score	2.951386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; hNPCs; hESCs; fibroblasts; A549; LCLs; H1299; Huh7; iSLK; MSC; TREX; AML
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq; miCLIP
Transcript ID List	ENST00000648046.1; ENST00000392564.5; ENST00000392562.5; ENST00000316804.10; ENST00000392563.5; ENST00000316615.9; ENST00000581959.1
External Link	RMBase: m6A_site_381831
mod ID: M6ASITE035260		Click to Show/Hide the Full List
mod site	chr17:75320288-75320289:-		[9]
Sequence	AAACCCACAAGCTGCCTCTGACAGCAGCCTGTGAGGGAGTG
Motif Score	2.859755952
Cell/Tissue List	kidney; HEK293T; hESC-HEK293T; AML
Seq Type List	m6A-REF-seq; DART-seq; MAZTER-seq; miCLIP
Transcript ID List	ENST00000392562.5; ENST00000392564.5; ENST00000581959.1; ENST00000316615.9; ENST00000392563.5; ENST00000316804.10; ENST00000648046.1
External Link	RMBase: m6A_site_381832
mod ID: M6ASITE035261		Click to Show/Hide the Full List
mod site	chr17:75320306-75320307:-		[7]
Sequence	AACACATACAAAAGAATTAAACCCACAAGCTGCCTCTGACA
Motif Score	2.185083333
Cell/Tissue List	HeLa; HEK293T; hNPCs; hESCs; fibroblasts; A549; LCLs; H1299; Huh7; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000316804.10; ENST00000392562.5; ENST00000392564.5; ENST00000648046.1; ENST00000392563.5; ENST00000581959.1; ENST00000316615.9
External Link	RMBase: m6A_site_381833
mod ID: M6ASITE035262		Click to Show/Hide the Full List
mod site	chr17:75320325-75320326:-		[7]
Sequence	AAGAAAGTGAAAAATGTAAAACACATACAAAAGAATTAAAC
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; hNPCs; hESCs; fibroblasts; A549; LCLs; H1299; Huh7
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000648046.1; ENST00000316804.10; ENST00000581959.1; ENST00000316615.9; ENST00000392562.5; ENST00000392564.5; ENST00000392563.5
External Link	RMBase: m6A_site_381834
mod ID: M6ASITE035263		Click to Show/Hide the Full List
mod site	chr17:75320380-75320381:-		[10]
Sequence	CAATTATGTCACCCCCGTGAACCGGAACGTCTAAGAGTCAA
Motif Score	2.930744048
Cell/Tissue List	HEK293T; Huh7; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000392562.5; ENST00000648046.1; ENST00000392564.5; ENST00000578961.5; ENST00000581959.1; ENST00000462266.1; ENST00000316804.10; ENST00000316615.9; ENST00000392563.5
External Link	RMBase: m6A_site_381835
mod ID: M6ASITE035264		Click to Show/Hide the Full List
mod site	chr17:75320417-75320418:-		[11]
Sequence	AAGGAGCTTGCCACGGGCAGACCGGCATGTTTCCCCGCAAT
Motif Score	2.876744048
Cell/Tissue List	Huh7; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000316615.9; ENST00000462266.1; ENST00000648046.1; ENST00000316804.10; ENST00000578961.5; ENST00000392562.5; ENST00000392563.5; ENST00000392564.5; ENST00000581959.1
External Link	RMBase: m6A_site_381836
mod ID: M6ASITE035265		Click to Show/Hide the Full List
mod site	chr17:75320425-75320426:-		[6]
Sequence	CTGGTGGAAAGGAGCTTGCCACGGGCAGACCGGCATGTTTC
Motif Score	2.027047619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000316615.9; ENST00000392562.5; ENST00000462266.1; ENST00000392563.5; ENST00000581959.1; ENST00000578961.5; ENST00000648046.1; ENST00000316804.10; ENST00000392564.5
External Link	RMBase: m6A_site_381837
mod ID: M6ASITE035266		Click to Show/Hide the Full List
mod site	chr17:75320452-75320453:-		[12]
Sequence	CCATGTCATGGATAACTCAGACCCCAACTGGTGGAAAGGAG
Motif Score	2.876744048
Cell/Tissue List	HepG2; Huh7; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000392562.5; ENST00000392564.5; ENST00000392563.5; ENST00000316615.9; ENST00000462266.1; ENST00000316804.10; ENST00000578961.5; ENST00000581959.1; ENST00000648046.1
External Link	RMBase: m6A_site_381838
mod ID: M6ASITE035267		Click to Show/Hide the Full List
mod site	chr17:75320524-75320525:-		[13]
Sequence	ATACGTCCAGGCCCTCTTTGACTTTGATCCCCAGGAGGATG
Motif Score	3.28175
Cell/Tissue List	AML
Seq Type List	miCLIP
Transcript ID List	ENST00000462266.1; ENST00000316615.9; ENST00000316804.10; ENST00000392562.5; ENST00000392564.5; ENST00000648046.1; ENST00000392563.5; ENST00000578961.5; ENST00000581959.1
External Link	RMBase: m6A_site_381839
mod ID: M6ASITE035268		Click to Show/Hide the Full List
mod site	chr17:75320546-75320547:-		[8]
Sequence	CTCCTGTTTTGCAGCAGCCGACATACGTCCAGGCCCTCTTT
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000462266.1; ENST00000316615.9; ENST00000578961.5; ENST00000392564.5; ENST00000648046.1; ENST00000392562.5; ENST00000392563.5; ENST00000316804.10; ENST00000581959.1
External Link	RMBase: m6A_site_381840
mod ID: M6ASITE035269		Click to Show/Hide the Full List
mod site	chr17:75321670-75321671:-		[14]
Sequence	ATATTCCTGCGGGACATAGAACAGGTGCCACAGGTAAGCCT
Motif Score	2.951386905
Cell/Tissue List	CD34; HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000316804.10; ENST00000316615.9; ENST00000581959.1; ENST00000392562.5; ENST00000392564.5; ENST00000578961.5; ENST00000392563.5; ENST00000462266.1; ENST00000648046.1
External Link	RMBase: m6A_site_381841
mod ID: M6ASITE035270		Click to Show/Hide the Full List
mod site	chr17:75321677-75321678:-		[14]
Sequence	CCAGCAGATATTCCTGCGGGACATAGAACAGGTGCCACAGG
Motif Score	3.643047619
Cell/Tissue List	CD34; HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000392564.5; ENST00000648046.1; ENST00000462266.1; ENST00000316615.9; ENST00000578961.5; ENST00000392562.5; ENST00000581959.1; ENST00000392563.5; ENST00000316804.10
External Link	RMBase: m6A_site_381842
mod ID: M6ASITE035271		Click to Show/Hide the Full List
mod site	chr17:75321698-75321699:-		[14]
Sequence	ATCTACATCTGTCTCCAGAAACCAGCAGATATTCCTGCGGG
Motif Score	2.185083333
Cell/Tissue List	CD34; HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000392562.5; ENST00000578961.5; ENST00000462266.1; ENST00000392563.5; ENST00000392564.5; ENST00000316804.10; ENST00000316615.9; ENST00000648046.1; ENST00000581959.1
External Link	RMBase: m6A_site_381843
mod ID: M6ASITE035272		Click to Show/Hide the Full List
mod site	chr17:75325915-75325916:-		[7]
Sequence	GAGTGAGAGCGCTCCTGGGGACTTCTCCCTCTCTGTCAAGT
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000316615.9; ENST00000392564.5; ENST00000316804.10; ENST00000582582.1; ENST00000578961.5; ENST00000392562.5; ENST00000462266.1; ENST00000392563.5; ENST00000648046.1
External Link	RMBase: m6A_site_381844
mod ID: M6ASITE035273		Click to Show/Hide the Full List
mod site	chr17:75325968-75325969:-		[7]
Sequence	GCAGAAGAAATGCTTAGCAAACAGCGGCACGATGGGGCCTT
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000316804.10; ENST00000392563.5; ENST00000316615.9; ENST00000392562.5; ENST00000582582.1; ENST00000578961.5; ENST00000648046.1; ENST00000392564.5; ENST00000462266.1
External Link	RMBase: m6A_site_381845
mod ID: M6ASITE035274		Click to Show/Hide the Full List
mod site	chr17:75332704-75332705:-		[8]
Sequence	AACTACATAGAAATGAAACCACATCCGTAAGTTAAGCTCCA
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000392563.5; ENST00000392564.5; ENST00000578961.5; ENST00000648046.1; ENST00000316804.10; ENST00000392562.5; ENST00000582582.1; ENST00000316615.9
External Link	RMBase: m6A_site_381846
mod ID: M6ASITE035275		Click to Show/Hide the Full List
mod site	chr17:75332707-75332708:-		[7]
Sequence	AAGAACTACATAGAAATGAAACCACATCCGTAAGTTAAGCT
Motif Score	2.185083333
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000316804.10; ENST00000392563.5; ENST00000392564.5; ENST00000578961.5; ENST00000582582.1; ENST00000648046.1; ENST00000392562.5; ENST00000316615.9
External Link	RMBase: m6A_site_381847
mod ID: M6ASITE035276		Click to Show/Hide the Full List
mod site	chr17:75332720-75332721:-		[8]
Sequence	CGGCTTCATTCCCAAGAACTACATAGAAATGAAACCACATC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000316804.10; ENST00000392562.5; ENST00000392563.5; ENST00000648046.1; ENST00000392564.5; ENST00000582582.1; ENST00000316615.9; ENST00000578961.5
External Link	RMBase: m6A_site_381848
mod ID: M6ASITE035277		Click to Show/Hide the Full List
mod site	chr17:75332723-75332724:-		[7]
Sequence	AGACGGCTTCATTCCCAAGAACTACATAGAAATGAAACCAC
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000392563.5; ENST00000392564.5; ENST00000582582.1; ENST00000316804.10; ENST00000316615.9; ENST00000648046.1; ENST00000392562.5; ENST00000578961.5
External Link	RMBase: m6A_site_381849
mod ID: M6ASITE035278		Click to Show/Hide the Full List
mod site	chr17:75332765-75332766:-		[8]
Sequence	AGAATGTGATCAGAACTGGTACAAGGCAGAGCTTAATGGAA
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000578961.5; ENST00000392564.5; ENST00000316804.10; ENST00000392563.5; ENST00000316615.9; ENST00000582582.1; ENST00000648046.1; ENST00000392562.5
External Link	RMBase: m6A_site_381850
mod ID: M6ASITE035279		Click to Show/Hide the Full List
mod site	chr17:75332771-75332772:-		[7]
Sequence	GAACGAAGAATGTGATCAGAACTGGTACAAGGCAGAGCTTA
Motif Score	3.373380952
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000392563.5; ENST00000582582.1; ENST00000316804.10; ENST00000648046.1; ENST00000316615.9; ENST00000392564.5; ENST00000578961.5; ENST00000392562.5
External Link	RMBase: m6A_site_381851
mod ID: M6ASITE035280		Click to Show/Hide the Full List
mod site	chr17:75387591-75387592:-		[7]
Sequence	GTTGGCCAGGCTGGTCTTAAACTCCTGACCTCAAATGATCC
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000582582.1; ENST00000316804.10; ENST00000316615.9; ENST00000392564.5; ENST00000578961.5; ENST00000648046.1; ENST00000392562.5; ENST00000583912.1; ENST00000392563.5
External Link	RMBase: m6A_site_381852
mod ID: M6ASITE035281		Click to Show/Hide the Full List
mod site	chr17:75393560-75393561:-		[9]
Sequence	GCTGAGCTTCAAAAGGGGGGACATCCTCAAGGTAAGTGCTG
Motif Score	3.643047619
Cell/Tissue List	liver; hESC-HEK293T; peripheral-blood
Seq Type List	m6A-REF-seq; MAZTER-seq; m6A-seq
Transcript ID List	ENST00000648046.1; ENST00000578961.5; ENST00000392564.5; ENST00000577711.1; ENST00000583912.1; ENST00000316615.9; ENST00000316804.10; ENST00000392563.5; ENST00000392562.5; ENST00000582582.1
External Link	RMBase: m6A_site_381853
mod ID: M6ASITE035282		Click to Show/Hide the Full List
mod site	chr17:75393675-75393676:-		[7]
Sequence	GGGTTGCTTCAGCAGGGAAGACTCCCTTCCCCCTGCTTCAG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; A549; U2OS; MT4; peripheral-blood; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000316804.10; ENST00000583912.1; ENST00000392562.5; ENST00000582582.1; ENST00000577711.1; ENST00000392564.5; ENST00000648046.1; ENST00000578961.5; ENST00000316615.9
External Link	RMBase: m6A_site_381854
mod ID: M6ASITE035283		Click to Show/Hide the Full List
mod site	chr17:75393839-75393840:-		[7]
Sequence	CAGGGGGCGTGGGGGCTGGGACAGCAGGCCGATTGGCAGGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; CD34; A549; U2OS; MT4; MM6; CD4T; GSC-11; HEK293T; TREX; iSLK; MSC; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000316804.10; ENST00000392564.5; ENST00000316615.9; ENST00000392562.5; ENST00000577711.1; ENST00000582582.1; ENST00000648046.1
External Link	RMBase: m6A_site_381855
mod ID: M6ASITE035284		Click to Show/Hide the Full List
mod site	chr17:75405695-75405696:-		[7]
Sequence	CGTGGAGAAGTTCTCGCGGGACACCGACGGGGAGCGGAAGC
Motif Score	3.643047619
Cell/Tissue List	HeLa; U2OS; A549; Jurkat; CD4T; GSC-11; HEK293T; HEK293A-TOA; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000648046.1; ENST00000316615.9
External Link	RMBase: m6A_site_381856

Pseudouridine (Pseudo)

In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000112		Click to Show/Hide the Full List
mod site	chr17:75321752-75321753:-		[15]
Sequence	CTTCCTCTGGGTGGTGAAGTTCAATTCTTTGAATGAGCTGG
Transcript ID List	ENST00000316804.10; ENST00000581959.1; ENST00000392564.5; ENST00000462266.1; ENST00000648046.1; ENST00000392562.5; ENST00000316615.9; ENST00000578961.5; ENST00000392563.5
External Link	RMBase: Pseudo_site_2284

Ref 1	URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1619).
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Nat Biotechnol. 2012 Feb 12;30(3):253-60. doi: 10.1038/nbt.2122.
Ref 4	Accurate identification of A-to-I RNA editing in human by transcriptome sequencing. Genome Res. 2012 Jan;22(1):142-50. doi: 10.1101/gr.124107.111. Epub 2011 Sep 29.
Ref 5	Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution. Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):6784-6789. doi: 10.1073/pnas.1817334116. Epub 2019 Mar 14.
Ref 6	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 7	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 8	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 9	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 10	Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons. Cell. 2012 Jun 22;149(7):1635-46. doi: 10.1016/j.cell.2012.05.003. Epub 2012 May 17.
Ref 11	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 12	Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature. 2012 Apr 29;485(7397):201-6. doi: 10.1038/nature11112.
Ref 13	The N(6)-methyladenosine (m(6)A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells. Nat Med. 2017 Nov;23(11):1369-1376. doi: 10.1038/nm.4416. Epub 2017 Sep 18.
Ref 14	Suppression of m(6)A reader Ythdf2 promotes hematopoietic stem cell expansion. Cell Res. 2018 Sep;28(9):904-917. doi: 10.1038/s41422-018-0072-0. Epub 2018 Jul 31.
Ref 15	Chemical pulldown reveals dynamic pseudouridylation of the mammalian transcriptome. Nat Chem Biol. 2015 Aug;11(8):592-7. doi: 10.1038/nchembio.1836. Epub 2015 Jun 15.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

Visitor Map