m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01352)

Target Name	Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3)
Synonyms	Glucose transporter type 3; brain; GLUT-3 Click to Show/Hide
Gene Name	SLC2A3
Chromosomal Location	12p13.31
Family	Major facilitator superfamily, Sugar transporter (TC 2.A.1.1) family, Glucose transporter subfamily
Function	Facilitative glucose transporter (PubMed:9477959, PubMed:26176916). Can also mediate the uptake of various other monosaccharides across the cell membrane (PubMed:9477959, PubMed:26176916). Mediates the uptake of glucose, 2-deoxyglucose, galactose, mannose, xylose and fucose, and probably also dehydroascorbate (PubMed:9477959, PubMed:26176916). Does not mediate fructose transport (PubMed:9477959, PubMed:26176916). Required for mesendoderm differentiation (By similarity). Click to Show/Hide
Gene ID	6515
Uniprot ID	GTR3_HUMAN
HGNC ID	HGNC:11007
KEGG ID	hsa:6515

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Non-coding RNA

m6A Regulator: Methyltransferase-like 14 (METTL14)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05152		Crosstalk Info
Epigenetic Regulator	hsa-miR-103-3p
Regulated Target	Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship	ncRNA → m6A
Disease	Osteoporosis	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01352)

Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3)

5-methylcytidine (m5C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE005450		Click to Show/Hide the Full List
mod site	chr12:7922982-7922983:-		[2]
Sequence	TTTGTCTGTATTGGGGCTATCTTGGTCTTTGTAGCCTTCTT
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000479059.3; ENST00000486749.5; ENST00000469295.1; ENST00000075120.12
External Link	RMBase: m5C_site_9636

N6-methyladenosine (m6A)

In total 39 m6A sequence/site(s) in this target gene
mod ID: M6ASITE010642		Click to Show/Hide the Full List
mod site	chr12:7919234-7919235:-		[3]
Sequence	AAAATAAAAATTCTGAATGTACACGACATTATGGGCTTATT
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000486749.5; ENST00000543435.1; ENST00000075120.12
External Link	RMBase: m6A_site_176042
mod ID: M6ASITE010643		Click to Show/Hide the Full List
mod site	chr12:7919422-7919423:-		[3]
Sequence	TCTCAAAAAAAAAAAAATGCACATAGCTATCAAGTGTGCTT
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000543435.1; ENST00000486749.5; ENST00000075120.12
External Link	RMBase: m6A_site_176043
mod ID: M6ASITE010644		Click to Show/Hide the Full List
mod site	chr12:7919819-7919820:-		[3]
Sequence	CCTTTCCCTTCTTGGTGCTTACACATCTCAGACCCTTTAGC
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000075120.12; ENST00000486749.5
External Link	RMBase: m6A_site_176044
mod ID: M6ASITE010645		Click to Show/Hide the Full List
mod site	chr12:7919959-7919960:-		[3]
Sequence	GTCAATGTGCAGTGTAGCCCACACTTGAGAGGATGAATGTA
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000486749.5; ENST00000075120.12
External Link	RMBase: m6A_site_176045
mod ID: M6ASITE010646		Click to Show/Hide the Full List
mod site	chr12:7920626-7920627:-		[3]
Sequence	GGTCTGTACGTTACCTCTTAACAATTTCTGTCCTTCAGATG
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000075120.12; ENST00000486749.5
External Link	RMBase: m6A_site_176046
mod ID: M6ASITE010647		Click to Show/Hide the Full List
mod site	chr12:7920787-7920788:-		[4]
Sequence	AATTTTGCCAAATAATAAAAACAGAAGGAAATTGAGATTAG
Motif Score	2.20572619
Cell/Tissue List	CD34; fibroblasts
Seq Type List	m6A-seq
Transcript ID List	ENST00000486749.5; ENST00000075120.12
External Link	RMBase: m6A_site_176047
mod ID: M6ASITE010648		Click to Show/Hide the Full List
mod site	chr12:7920917-7920918:-		[3]
Sequence	TTTTATCCTCTGGTTTAATTACATAATTTTTTTTTTTTAAC
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000486749.5; ENST00000075120.12
External Link	RMBase: m6A_site_176048
mod ID: M6ASITE010649		Click to Show/Hide the Full List
mod site	chr12:7921031-7921032:-		[3]
Sequence	AGACTTACCAGGAAGCAGATACATATGAGTGTGGAAGCCGG
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000486749.5; ENST00000075120.12
External Link	RMBase: m6A_site_176049
mod ID: M6ASITE010650		Click to Show/Hide the Full List
mod site	chr12:7921049-7921050:-		[5]
Sequence	TGCAGTTCCCCCAACCTCAGACTTACCAGGAAGCAGATACA
Motif Score	3.319380952
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MT4; H1299; MM6; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; MSC; TIME; TREX; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000075120.12; ENST00000486749.5
External Link	RMBase: m6A_site_176050
mod ID: M6ASITE010651		Click to Show/Hide the Full List
mod site	chr12:7921184-7921185:-		[5]
Sequence	GCTTAGGAGAGACCGAGTGAACCTACCTTCATTTCAGGAGG
Motif Score	2.930744048
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MT4; H1299; MM6; Jurkat; CD4T; HEK293A-TOA; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000486749.5; ENST00000075120.12; ENST00000469295.1
External Link	RMBase: m6A_site_176051
mod ID: M6ASITE010652		Click to Show/Hide the Full List
mod site	chr12:7921193-7921194:-		[5]
Sequence	TCCTCTTCTGCTTAGGAGAGACCGAGTGAACCTACCTTCAT
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MT4; H1299; MM6; Jurkat; CD4T; HEK293A-TOA; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000075120.12; ENST00000486749.5; ENST00000469295.1
External Link	RMBase: m6A_site_176052
mod ID: M6ASITE010653		Click to Show/Hide the Full List
mod site	chr12:7921216-7921217:-		[5]
Sequence	TTTTAAATTTTATTTCCTGGACATCCTCTTCTGCTTAGGAG
Motif Score	3.643047619
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1B; H1A; hESCs; fibroblasts; GM12878; LCLs; MT4; H1299; MM6; HEK293A-TOA; MSC; TIME; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000469295.1; ENST00000486749.5; ENST00000075120.12
External Link	RMBase: m6A_site_176053
mod ID: M6ASITE010654		Click to Show/Hide the Full List
mod site	chr12:7921326-7921327:-		[6]
Sequence	CTCATCAGGATGAACCCAGGACGCTTCTGAATGCTGCTACT
Motif Score	3.616982143
Cell/Tissue List	CD8T; A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000075120.12; ENST00000469295.1; ENST00000486749.5
External Link	RMBase: m6A_site_176054
mod ID: M6ASITE010655		Click to Show/Hide the Full List
mod site	chr12:7921333-7921334:-		[5]
Sequence	GAGAGACCTCATCAGGATGAACCCAGGACGCTTCTGAATGC
Motif Score	2.930744048
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; CD8T; MT4; H1299; MM6; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; MSC; TIME; TREX; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000486749.5; ENST00000469295.1; ENST00000075120.12
External Link	RMBase: m6A_site_176055
mod ID: M6ASITE010656		Click to Show/Hide the Full List
mod site	chr12:7921348-7921349:-		[5]
Sequence	TCTCCCTCAACAAGGGAGAGACCTCATCAGGATGAACCCAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MT4; H1299; MM6; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; MSC; TIME; TREX; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000486749.5; ENST00000469295.1; ENST00000075120.12
External Link	RMBase: m6A_site_176056
mod ID: M6ASITE010657		Click to Show/Hide the Full List
mod site	chr12:7921359-7921360:-		[3]
Sequence	GGAAAGCCACCTCTCCCTCAACAAGGGAGAGACCTCATCAG
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T; A549
Seq Type List	MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000469295.1; ENST00000075120.12; ENST00000486749.5
External Link	RMBase: m6A_site_176057
mod ID: M6ASITE010658		Click to Show/Hide the Full List
mod site	chr12:7921429-7921430:-		[5]
Sequence	GCATCGAGCCTGCTAAGGAGACCACCACCAATGTCTAAGTC
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; Brain; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MT4; H1299; MM6; Jurkat; CD4T; HEK293A-TOA; MSC; TIME; TREX; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000469295.1; ENST00000075120.12; ENST00000486749.5
External Link	RMBase: m6A_site_176058
mod ID: M6ASITE010659		Click to Show/Hide the Full List
mod site	chr12:7921452-7921453:-		[5]
Sequence	GGACGGCGTCATGGAGATGAACAGCATCGAGCCTGCTAAGG
Motif Score	2.951386905
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; brain; A549; hESC-HEK293T; Brain; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Jurkat; CD4T; HEK293A-TOA; MSC; TIME; TREX; endometrial; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; m6A-REF-seq; MAZTER-seq; miCLIP
Transcript ID List	ENST00000469295.1; ENST00000075120.12; ENST00000486749.5
External Link	RMBase: m6A_site_176059
mod ID: M6ASITE010660		Click to Show/Hide the Full List
mod site	chr12:7921470-7921471:-		[6]
Sequence	TGCAGATAGATCTGGAAAGGACGGCGTCATGGAGATGAACA
Motif Score	3.616982143
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000486749.5; ENST00000075120.12; ENST00000469295.1
External Link	RMBase: m6A_site_176060
mod ID: M6ASITE010661		Click to Show/Hide the Full List
mod site	chr12:7921496-7921497:-		[3]
Sequence	CGGGCCTTTGAAGGGCAGGCACACGGTGCAGATAGATCTGG
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000486749.5; ENST00000075120.12; ENST00000469295.1
External Link	RMBase: m6A_site_176061
mod ID: M6ASITE010662		Click to Show/Hide the Full List
mod site	chr12:7921534-7921535:-		[5]
Sequence	TCCCTGAGACCCGTGGCAGGACTTTTGAGGATATCACACGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34; HEK293T; A549; HepG2; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Jurkat; HEK293A-TOA; MSC; TIME; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000486749.5; ENST00000075120.12; ENST00000469295.1
External Link	RMBase: m6A_site_176062
mod ID: M6ASITE010663		Click to Show/Hide the Full List
mod site	chr12:7921546-7921547:-		[5]
Sequence	CCTTCTTCAAAGTCCCTGAGACCCGTGGCAGGACTTTTGAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HEK293T; A549; HepG2; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Jurkat; HEK293A-TOA; MSC; TIME; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000479059.3; ENST00000486749.5; ENST00000075120.12; ENST00000469295.1
External Link	RMBase: m6A_site_176063
mod ID: M6ASITE010664		Click to Show/Hide the Full List
mod site	chr12:7922861-7922862:-		[7]
Sequence	TGGCCGGCTGCTCCAACTGGACCTCCAACTTCCTAGTCGGA
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000075120.12; ENST00000479059.3; ENST00000486749.5; ENST00000469295.1
External Link	RMBase: m6A_site_176064
mod ID: M6ASITE010665		Click to Show/Hide the Full List
mod site	chr12:7929794-7929795:-		[3]
Sequence	GATGAGAGTGCAAGGATGTCACAAGAAAAGCAAGTCACCGT
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000479059.3; ENST00000486749.5; ENST00000495813.5; ENST00000075120.12; ENST00000490763.1
External Link	RMBase: m6A_site_176065
mod ID: M6ASITE010666		Click to Show/Hide the Full List
mod site	chr12:7929831-7929832:-		[5]
Sequence	CACCCAGGATGTATCCCAAGACATCCAGGAGATGAAAGATG
Motif Score	2.897386905
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000075120.12; ENST00000486749.5; ENST00000495813.5; ENST00000479059.3; ENST00000490763.1
External Link	RMBase: m6A_site_176066
mod ID: M6ASITE010667		Click to Show/Hide the Full List
mod site	chr12:7930011-7930012:-		[8]
Sequence	GCCTGGGCAACAAAAGTGAAACTCTGTCTCAAAAAAAAAAA
Motif Score	2.627720238
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000486749.5; rmsk_3717224; ENST00000495813.5; ENST00000490763.1; ENST00000075120.12; ENST00000479059.3
External Link	RMBase: m6A_site_176067
mod ID: M6ASITE010668		Click to Show/Hide the Full List
mod site	chr12:7930561-7930562:-		[3]
Sequence	ACCATCCTTCCTGCTATCCTACAAAGTGCAGCCCTTCCATT
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000495813.5; ENST00000075120.12; ENST00000486749.5
External Link	RMBase: m6A_site_176068
mod ID: M6ASITE010669		Click to Show/Hide the Full List
mod site	chr12:7931332-7931333:-		[3]
Sequence	CACAGGTTTTGTGCCCATGTACATTGGAGAGATCTCGCCTA
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000495813.5; ENST00000544291.1; ENST00000075120.12; ENST00000486749.5
External Link	RMBase: m6A_site_176069
mod ID: M6ASITE010670		Click to Show/Hide the Full List
mod site	chr12:7931358-7931359:-		[5]
Sequence	GTTATTGGCCTCTTCTGCGGACTCTGCACAGGTTTTGTGCC
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000544291.1; ENST00000075120.12; ENST00000544936.1; ENST00000495813.5; ENST00000486749.5
External Link	RMBase: m6A_site_176070
mod ID: M6ASITE010671		Click to Show/Hide the Full List
mod site	chr12:7931427-7931428:-		[5]
Sequence	ACTGGTGGCTGCTTTATGGGACTGTGTAAAGTAGCTAAGTC
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34
Seq Type List	m6A-seq
Transcript ID List	ENST00000075120.12; ENST00000486749.5; ENST00000495813.5; ENST00000544291.1; ENST00000544936.1
External Link	RMBase: m6A_site_176071
mod ID: M6ASITE010672		Click to Show/Hide the Full List
mod site	chr12:7933009-7933010:-		[5]
Sequence	ATCGGCTCCTTTTCCGTCGGACTCTTCGTCAACCGCTTTGG
Motif Score	4.065041667
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000544291.1; ENST00000495813.5; ENST00000544936.1; ENST00000476634.1; ENST00000486749.5; ENST00000075120.12
External Link	RMBase: m6A_site_176072
mod ID: M6ASITE010673		Click to Show/Hide the Full List
mod site	chr12:7933112-7933113:-		[5]
Sequence	TATCAATAAAACTTTGACGGACAAGGGAAATGCCCCACCCT
Motif Score	3.643047619
Cell/Tissue List	HeLa; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000544291.1; ENST00000075120.12; ENST00000476634.1; ENST00000495813.5; ENST00000486749.5; ENST00000544936.1
External Link	RMBase: m6A_site_176073
mod ID: M6ASITE010674		Click to Show/Hide the Full List
mod site	chr12:7933122-7933123:-		[5]
Sequence	TAAAGGAATTTATCAATAAAACTTTGACGGACAAGGGAAAT
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000495813.5; ENST00000075120.12; ENST00000476634.1; ENST00000486749.5; ENST00000544291.1; ENST00000544936.1
External Link	RMBase: m6A_site_176074
mod ID: M6ASITE010675		Click to Show/Hide the Full List
mod site	chr12:7933837-7933838:-		[3]
Sequence	CTCTTTCCAATTTGGCTACAACACTGGGGTCATCAATGCTC
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000075120.12; ENST00000486749.5; ENST00000541671.1; ENST00000495813.5; ENST00000544936.1; ENST00000476634.1; ENST00000544291.1
External Link	RMBase: m6A_site_176075
mod ID: M6ASITE010676		Click to Show/Hide the Full List
mod site	chr12:7936027-7936028:-		[5]
Sequence	ATTAGATTACAGCGATGGGGACACAGAAGGTAAGAATGATA
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; A549; LCLs; Jurkat; CD4T; MSC; TIME; TREX; endometrial; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000544936.1; ENST00000495813.5; ENST00000541671.1; ENST00000544291.1; ENST00000476634.1; ENST00000486749.5; ENST00000075120.12
External Link	RMBase: m6A_site_176076
mod ID: M6ASITE010677		Click to Show/Hide the Full List
mod site	chr12:7936053-7936054:-		[5]
Sequence	CCCCTAGATCTTTCTTGAAGACTTGAATTAGATTACAGCGA
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; A549; fibroblasts; LCLs; Jurkat; CD4T; HEK293A-TOA; MSC; TIME; TREX; endometrial; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000544291.1; ENST00000495813.5; ENST00000544936.1; ENST00000476634.1; ENST00000541671.1; ENST00000075120.12; ENST00000486749.5
External Link	RMBase: m6A_site_176077
mod ID: M6ASITE010678		Click to Show/Hide the Full List
mod site	chr12:7936118-7936119:-		[5]
Sequence	AAAACTTGCTGCTGAGAAGGACATTTTGAAGGTTTTGTTGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; A549; hESC-HEK293T; hESCs; fibroblasts; LCLs; Jurkat; CD4T; HEK293A-TOA; MSC; TIME; TREX; endometrial; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000544936.1; ENST00000476634.1; ENST00000486749.5; ENST00000075120.12; ENST00000541671.1; ENST00000544291.1; ENST00000495813.5
External Link	RMBase: m6A_site_176078
mod ID: M6ASITE010679		Click to Show/Hide the Full List
mod site	chr12:7936135-7936136:-		[5]
Sequence	TTCCTGAGGACGTGGAGAAAACTTGCTGCTGAGAAGGACAT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; A549; hESCs; HEK293T; fibroblasts; LCLs; Jurkat; CD4T; HEK293A-TOA; MSC; TIME; TREX; endometrial; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000495813.5; ENST00000075120.12; ENST00000544936.1; ENST00000476634.1; ENST00000486749.5; ENST00000541671.1; ENST00000544291.1
External Link	RMBase: m6A_site_176079
mod ID: M6ASITE010680		Click to Show/Hide the Full List
mod site	chr12:7936166-7936167:-		[5]
Sequence	AGAGATGCTGTAATGGTAAGACTTTGGATCCTTCCTGAGGA
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; hESCs; HEK293T; fibroblasts; A549; LCLs; MM6; Jurkat; CD4T; HEK293A-TOA; MSC; TIME; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000541671.1; ENST00000544291.1; ENST00000495813.5; ENST00000486749.5; ENST00000075120.12; ENST00000476634.1; ENST00000544936.1
External Link	RMBase: m6A_site_176080

Pseudouridine (Pseudo)

In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000010		Click to Show/Hide the Full List
mod site	chr12:7919406-7919407:-		[9]
Sequence	ATGCACATAGCTATCAAGTGTGCTTTAGCTTGAAAAGGTGA
Transcript ID List	ENST00000075120.12; ENST00000486749.5; ENST00000543435.1
External Link	RMBase: Pseudo_site_1068

Ref 1	Transport of selected PET radiotracers by human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2): an in vitro screening. J Nucl Med. 2011 Mar;52(3):415-23.
Ref 2	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 3	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 4	Suppression of m(6)A reader Ythdf2 promotes hematopoietic stem cell expansion. Cell Res. 2018 Sep;28(9):904-917. doi: 10.1038/s41422-018-0072-0. Epub 2018 Jul 31.
Ref 5	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 6	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 7	N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505(7481):117-20. doi: 10.1038/nature12730. Epub 2013 Nov 27.
Ref 8	m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27.
Ref 9	Transcriptome-wide mapping reveals widespread dynamic-regulated pseudouridylation of ncRNA and mRNA. Cell. 2014 Sep 25;159(1):148-162. doi: 10.1016/j.cell.2014.08.028. Epub 2014 Sep 11.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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