m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01333)
Target Name Methylosome protein WDR77 (WDR77)
Synonyms
Androgen receptor cofactor p44; Methylosome protein 50; MEP-50; WD repeat-containing protein 77; p44/Mep50
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Gene Name WDR77
Chromosomal Location 1p13.2
Function
Non-catalytic component of the methylosome complex, composed of PRMT5, WDR77 and CLNS1A, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones (PubMed:11756452). This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The methylosome complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage (PubMed:23071334).
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Gene ID 79084
Uniprot ID
MEP50_HUMAN
HGNC ID
HGNC:29652
KEGG ID
hsa:79084
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
Non-coding RNA
m6A Regulator: Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC)
 Regulator Info 
In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05075
 Crosstalk Info 
Epigenetic Regulator hsa-miR-944
Regulated Target Heterogeneous nuclear ribonucleoprotein C (HNRNPC)
Crosstalk relationship ncRNA → m6A
Disease Breast cancer
 Disease Info 
Crosstalk ID: M6ACROT05077
 Crosstalk Info 
Epigenetic Regulator Circ_BACH2
Regulated Target hsa-miR-944
Crosstalk relationship ncRNA → m6A
Disease Breast cancer
 Disease Info 
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01333)
Methylosome protein WDR77 (WDR77)
5-methylcytidine (m5C)
In total 2 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002940 Click to Show/Hide the Full List
mod site chr1:111447109-111447110:- [2]
Sequence ACCTTGCTCAGCAGGTGGTACTGAGTTCATACCGAGGTGAG
Seq Type List Bisulfite-seq
Transcript ID List ENST00000449340.1; ENST00000459665.1; ENST00000235090.10; ENST00000497278.5
External Link RMBase: m5C_site_3110
mod ID: M5CSITE002941 Click to Show/Hide the Full List
mod site chr1:111448683-111448684:-
Sequence CTGCTCCGCCGGAGTCCAAACGGAGGCTGGAGTGGCTGACC
Cell/Tissue List testis
Seq Type List Bisulfite-seq
Transcript ID List ENST00000459665.1; ENST00000235090.10; ENST00000449340.1
External Link RMBase: m5C_site_3111
N6-methyladenosine (m6A)
In total 35 m6A sequence/site(s) in this target gene
mod ID: M6ASITE042228 Click to Show/Hide the Full List
mod site chr1:111440306-111440307:- [3]
Sequence TCAAGAAGAAAATCAGAAATACTGGTTGGTGAAATAAAGAG
Motif Score 2.53247619
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000445680.1; ENST00000416099.1; ENST00000235090.10
External Link RMBase: m6A_site_45054
mod ID: M6ASITE042229 Click to Show/Hide the Full List
mod site chr1:111440351-111440352:- [4]
Sequence TCTGAATGCAGTATTTATAGACTTCTAAGGTTTTAAAATCC
Motif Score 3.319380952
Cell/Tissue List HeLa; HEK293T
Seq Type List m6A-seq; DART-seq
Transcript ID List ENST00000416099.1; ENST00000235090.10; ENST00000445680.1
External Link RMBase: m6A_site_45055
mod ID: M6ASITE042230 Click to Show/Hide the Full List
mod site chr1:111440411-111440412:- [5]
Sequence CCAAAACAGCATGGGGCCTGACATCTTCTGCCCTGGTCCCC
Motif Score 2.859755952
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000445680.1; ENST00000416099.1; ENST00000235090.10
External Link RMBase: m6A_site_45056
mod ID: M6ASITE042231 Click to Show/Hide the Full List
mod site chr1:111440469-111440470:- [5]
Sequence TCAATTAAGTTAGAAAACTGACACAGGCTGTTGAGAATTCT
Motif Score 2.859755952
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000235090.10; ENST00000416099.1; ENST00000445680.1
External Link RMBase: m6A_site_45057
mod ID: M6ASITE042232 Click to Show/Hide the Full List
mod site chr1:111440535-111440536:- [5]
Sequence GAAGTGTTTTTCTATCATAGACACCATAGGGGAAAGTTTGG
Motif Score 2.897386905
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000235090.10; ENST00000416099.1; ENST00000445680.1
External Link RMBase: m6A_site_45058
mod ID: M6ASITE042233 Click to Show/Hide the Full List
mod site chr1:111440569-111440570:- [5]
Sequence CCTGGCTCCCTAGTGATGGGACATATATGAGAGAGAAGTGT
Motif Score 3.643047619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000235090.10; ENST00000445680.1; ENST00000416099.1
External Link RMBase: m6A_site_45059
mod ID: M6ASITE042234 Click to Show/Hide the Full List
mod site chr1:111440660-111440661:- [6]
Sequence ACACAACTCCTTACCATTAAACTGAATCAGAAATCCATTTT
Motif Score 2.627720238
Cell/Tissue List AML
Seq Type List miCLIP
Transcript ID List ENST00000445680.1; ENST00000235090.10; ENST00000416099.1
External Link RMBase: m6A_site_45060
mod ID: M6ASITE042235 Click to Show/Hide the Full List
mod site chr1:111440680-111440681:- [3]
Sequence GCAGGACTTGGTACGGTTTTACACAACTCCTTACCATTAAA
Motif Score 2.07285119
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000235090.10; ENST00000416099.1; ENST00000445680.1
External Link RMBase: m6A_site_45061
mod ID: M6ASITE042236 Click to Show/Hide the Full List
mod site chr1:111440734-111440735:- [3]
Sequence TATGAGAAATGCTTCCAGTCACAAAAATGCAGCCCAGCTCA
Motif Score 2.047297619
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000416099.1; ENST00000235090.10; ENST00000445680.1
External Link RMBase: m6A_site_45062
mod ID: M6ASITE042237 Click to Show/Hide the Full List
mod site chr1:111440786-111440787:- [3]
Sequence TACTCATAGAGATGGGATTGACTTTATTTTTTTATAGTGCT
Motif Score 3.28175
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000235090.10; ENST00000445680.1; ENST00000416099.1
External Link RMBase: m6A_site_45063
mod ID: M6ASITE042238 Click to Show/Hide the Full List
mod site chr1:111440904-111440905:- [3]
Sequence TCACCCCCCAAAACAAGTTGACGAAAGGGTTTTATGTAGCT
Motif Score 2.833690476
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000445680.1; ENST00000416099.1; ENST00000235090.10
External Link RMBase: m6A_site_45064
mod ID: M6ASITE042239 Click to Show/Hide the Full List
mod site chr1:111440912-111440913:- [4]
Sequence CCTCTCTCTCACCCCCCAAAACAAGTTGACGAAAGGGTTTT
Motif Score 2.20572619
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000445680.1; ENST00000235090.10; ENST00000416099.1
External Link RMBase: m6A_site_45065
mod ID: M6ASITE042240 Click to Show/Hide the Full List
mod site chr1:111440951-111440952:- [5]
Sequence GAATAAAAAAAATCCATCCTACATCTTCCCTAAGCACTGCC
Motif Score 2.078666667
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000445680.1; ENST00000416099.1; ENST00000235090.10
External Link RMBase: m6A_site_45066
mod ID: M6ASITE042241 Click to Show/Hide the Full List
mod site chr1:111441025-111441026:- [4]
Sequence AAAAGCTTTCTTAAAAATGGACATGTATGTGCGTGTGAGTG
Motif Score 3.643047619
Cell/Tissue List HeLa; HEK293T; hESC-HEK293T; HepG2; hESCs; fibroblasts; AML
Seq Type List m6A-seq; DART-seq; MAZTER-seq; miCLIP
Transcript ID List ENST00000235090.10; ENST00000416099.1; ENST00000445680.1
External Link RMBase: m6A_site_45067
mod ID: M6ASITE042242 Click to Show/Hide the Full List
mod site chr1:111441154-111441155:- [5]
Sequence CCCTCTCAGCTTGTGAGACAACACAGGAGCCTTCTATAGTA
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000445680.1; ENST00000235090.10; ENST00000416099.1
External Link RMBase: m6A_site_45068
mod ID: M6ASITE042243 Click to Show/Hide the Full List
mod site chr1:111441157-111441158:- [3]
Sequence CTGCCCTCTCAGCTTGTGAGACAACACAGGAGCCTTCTATA
Motif Score 2.897386905
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000445680.1; ENST00000235090.10; ENST00000416099.1
External Link RMBase: m6A_site_45069
mod ID: M6ASITE042244 Click to Show/Hide the Full List
mod site chr1:111441216-111441217:- [3]
Sequence CTGAGTAGATTGGATTTAAGACAAAAAGCAAGTCCCCCATG
Motif Score 2.897386905
Cell/Tissue List HEK293T; hESC-HEK293T; endometrial
Seq Type List DART-seq; MAZTER-seq; m6A-seq
Transcript ID List ENST00000235090.10; ENST00000416099.1; ENST00000445680.1
External Link RMBase: m6A_site_45070
mod ID: M6ASITE042245 Click to Show/Hide the Full List
mod site chr1:111441237-111441238:- [3]
Sequence CCCCTGGACCTGCAAGTGTTACTGAGTAGATTGGATTTAAG
Motif Score 2.494845238
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000235090.10; ENST00000445680.1; ENST00000449340.1
External Link RMBase: m6A_site_45071
mod ID: M6ASITE042246 Click to Show/Hide the Full List
mod site chr1:111441250-111441251:- [7]
Sequence GAACCTCTCCCAGCCCCTGGACCTGCAAGTGTTACTGAGTA
Motif Score 3.622404762
Cell/Tissue List endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000449340.1; ENST00000235090.10; ENST00000445680.1
External Link RMBase: m6A_site_45072
mod ID: M6ASITE042247 Click to Show/Hide the Full List
mod site chr1:111441268-111441269:- [7]
Sequence CACCACGTTGTGCCCACAGAACCTCTCCCAGCCCCTGGACC
Motif Score 2.930744048
Cell/Tissue List endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000235090.10; ENST00000445680.1; ENST00000449340.1
External Link RMBase: m6A_site_45073
mod ID: M6ASITE042248 Click to Show/Hide the Full List
mod site chr1:111441302-111441303:- [7]
Sequence GCTTACCACAGTGGGCTGGGACCATCAGGTCGTCCACCACG
Motif Score 3.622404762
Cell/Tissue List endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000497278.5; ENST00000449340.1; ENST00000235090.10; ENST00000445680.1
External Link RMBase: m6A_site_45074
mod ID: M6ASITE042249 Click to Show/Hide the Full List
mod site chr1:111441365-111441366:- [7]
Sequence TAGAAGCCAAGCCCACAGAGACTTTGTGAGAGATGCGACTT
Motif Score 3.319380952
Cell/Tissue List endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000497278.5; ENST00000449340.1; ENST00000235090.10
External Link RMBase: m6A_site_45075
mod ID: M6ASITE042250 Click to Show/Hide the Full List
mod site chr1:111442063-111442064:- [4]
Sequence CCTGGCCTCTCTCAGTGAAGACTGCTCACTTGCTGTGCTGG
Motif Score 3.319380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000497278.5; ENST00000449340.1; ENST00000235090.10
External Link RMBase: m6A_site_45076
mod ID: M6ASITE042251 Click to Show/Hide the Full List
mod site chr1:111442123-111442124:- [4]
Sequence TGTCTTGGGATCCAGGCTGGACCTTTCACAACCCTCTCCTC
Motif Score 3.622404762
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000497278.5; ENST00000235090.10; ENST00000449340.1
External Link RMBase: m6A_site_45077
mod ID: M6ASITE042252 Click to Show/Hide the Full List
mod site chr1:111443919-111443920:- [5]
Sequence CTGTTCCACCTTCCTCTAGGACAATAGAATTTTACTCTGGG
Motif Score 3.643047619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000459665.1; ENST00000449340.1; ENST00000497278.5; ENST00000235090.10
External Link RMBase: m6A_site_45078
mod ID: M6ASITE042253 Click to Show/Hide the Full List
mod site chr1:111444084-111444085:- [5]
Sequence TTGTGTTGCTGCCTCTCCTCACAAGGACTCTGTGTTTCTTT
Motif Score 2.047297619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000497278.5; ENST00000459665.1; ENST00000449340.1; ENST00000235090.10
External Link RMBase: m6A_site_45079
mod ID: M6ASITE042254 Click to Show/Hide the Full List
mod site chr1:111447440-111447441:- [5]
Sequence AGCTGTCAGTGGTAGCAAAGACATCTGGTGGGTCCCTGTTC
Motif Score 2.897386905
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000459665.1; ENST00000449340.1; ENST00000235090.10; ENST00000497278.5
External Link RMBase: m6A_site_45080
mod ID: M6ASITE042255 Click to Show/Hide the Full List
mod site chr1:111447500-111447501:- [5]
Sequence CTGCAAGTATGAGCATGATGACATTGTGTCTACAGTCAGTG
Motif Score 2.859755952
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000459665.1; ENST00000449340.1; ENST00000235090.10; ENST00000497278.5
External Link RMBase: m6A_site_45081
mod ID: M6ASITE042256 Click to Show/Hide the Full List
mod site chr1:111447540-111447541:- [5]
Sequence GGGAACTAGATGAGAATGAGACACTTATTGTCAGCAAGTTC
Motif Score 2.897386905
Cell/Tissue List hESC-HEK293T; peripheral-blood
Seq Type List MAZTER-seq; m6A-seq
Transcript ID List ENST00000459665.1; ENST00000235090.10; ENST00000449340.1
External Link RMBase: m6A_site_45082
mod ID: M6ASITE042257 Click to Show/Hide the Full List
mod site chr1:111447556-111447557:- [8]
Sequence GGTGCTGTTGAATTGTGGGAACTAGATGAGAATGAGACACT
Motif Score 3.373380952
Cell/Tissue List peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000459665.1; ENST00000235090.10; ENST00000449340.1
External Link RMBase: m6A_site_45083
mod ID: M6ASITE042258 Click to Show/Hide the Full List
mod site chr1:111448731-111448732:- [4]
Sequence CTCCCTCTGGCTTTTTAAGGACCCCTGTGCCGCCCCCAACG
Motif Score 3.622404762
Cell/Tissue List HeLa; HepG2; peripheral-blood; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000235090.10; ENST00000459665.1
External Link RMBase: m6A_site_45084
mod ID: M6ASITE042259 Click to Show/Hide the Full List
mod site chr1:111448846-111448847:- [4]
Sequence TGCGGTCTCCATGGAGGCGAACCCTTCTACCCTTCACGCGC
Motif Score 2.930744048
Cell/Tissue List HeLa; HepG2; peripheral-blood; GSC-11; endometrial
Seq Type List m6A-seq
Transcript ID List ENST00000235090.10; ENST00000459665.1
External Link RMBase: m6A_site_45085
mod ID: M6ASITE042260 Click to Show/Hide the Full List
mod site chr1:111448888-111448889:- [4]
Sequence GTTCCTGAGCTCAGATCCAGACCCGGCCGGAACGCTGTTCT
Motif Score 2.876744048
Cell/Tissue List HeLa; HepG2; A549; peripheral-blood; GSC-11; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000459665.1; ENST00000235090.10
External Link RMBase: m6A_site_45087
mod ID: M6ASITE042261 Click to Show/Hide the Full List
mod site chr1:111449156-111449157:- [4]
Sequence CCGTGGAGATGCGGAAGGAAACCCCACCCCCCCTAGTGCCC
Motif Score 2.185083333
Cell/Tissue List HeLa; HepG2; A549; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000235090.10
External Link RMBase: m6A_site_45089
mod ID: M6ASITE042262 Click to Show/Hide the Full List
mod site chr1:111449177-111449178:- [4]
Sequence GAGTCTAGGTTGGAGTTGGAACCGTGGAGATGCGGAAGGAA
Motif Score 2.930744048
Cell/Tissue List HeLa; HepG2; A549; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000235090.10
External Link RMBase: m6A_site_45090