m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01013)

Target Name	small nucleolar RNA host gene 15 (SNHG15)
Synonyms	FLJ38860; MYO1GUT; Linc-Myo1g; MYO1G upstream transcript; C7orf40; chromosome 7 open reading frame 40 Click to Show/Hide
Gene Name	SNHG15
Chromosomal Location	7p13
Gene ID	285958
HGNC ID	HGNC:27797

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Histone modification

m6A Regulator: RNA demethylase ALKBH5 (ALKBH5)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03066		Crosstalk Info
Epigenetic Regulator	Histone-lysine N-methyltransferase SETD2 (SETD2)
Regulated Target	Histone H3 lysine 36 trimethylation (H3K36me3)
Crosstalk relationship	m6A → Histone modification
Disease	Multiple myeloma	Disease Info

Non-coding RNA

m6A Regulator: RNA demethylase ALKBH5 (ALKBH5)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05733		Crosstalk Info
Epigenetic Regulator	Small nucleolar RNA host gene 15 (SNHG15)
Regulated Target	Histone-lysine N-methyltransferase SETD2 (SETD2)
Crosstalk relationship	m6A → ncRNA
Disease	Multiple myeloma	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01013)

small nucleolar RNA host gene 15 (SNHG15)

N4-acetylcytidine (ac4C)

In total 2 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000119		Click to Show/Hide the Full List
mod site	chr7:44984022-44984023:-		[2]
Sequence	CCATGAAACTGGGAGGCGACCGTGTTAGCTGCCAGTTCCTG
Cell/Tissue List	HEK293T
Seq Type List	ac4C-seq
Transcript ID List	ENST00000577700.5; ENST00000579383.5; ENST00000584327.5; rmsk_2221712; ENST00000585030.5; ENST00000584686.1; ENST00000580458.5; ENST00000438705.3; ENST00000582727.1; ENST00000578968.5
External Link	RMBase: ac4C_site_1654
mod ID: AC4SITE000120		Click to Show/Hide the Full List
mod site	chr7:44985203-44985204:-		[3]
Sequence	CAGTGGCTACCATATTGGACCGCACAGATTAGAGGGCATTT
Cell/Tissue List	H1
Seq Type List	ac4C-seq
Transcript ID List	ENST00000582727.1; ENST00000584327.5; ENST00000438705.3; ENST00000577700.5; ENST00000580458.5; ENST00000584686.1; ENST00000585030.5; ENST00000579383.5; ENST00000578968.5
External Link	RMBase: ac4C_site_1655

N6-methyladenosine (m6A)

In total 16 m6A sequence/site(s) in this target gene
mod ID: M6ASITE080102		Click to Show/Hide the Full List
mod site	chr7:44983059-44983060:-		[4]
Sequence	TGGTATCTCCTGAATGAAAAACAAGGGATATTTAATAAATA
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000585030.5; ENST00000577700.5; ENST00000580458.5; ENST00000578968.5; ENST00000579383.5
External Link	RMBase: m6A_site_756799
mod ID: M6ASITE080103		Click to Show/Hide the Full List
mod site	chr7:44983300-44983301:-		[4]
Sequence	TGAGGCCTGCCTGTGTTAATACACCTAGTGAGGAGTGGAGC
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000580458.5; ENST00000584327.5; ENST00000585030.5; ENST00000577700.5; ENST00000578968.5; ENST00000579383.5; ENST00000438705.3
External Link	RMBase: m6A_site_756800
mod ID: M6ASITE080104		Click to Show/Hide the Full List
mod site	chr7:44984816-44984817:-		[4]
Sequence	GAGGAAGGTGCTAATGTTGAACACCTATTTTGCGCCAGACC
Motif Score	2.951386905
Cell/Tissue List	hESC-HEK293T; Huh7
Seq Type List	MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000580458.5; ENST00000577700.5; ENST00000584327.5; ENST00000582727.1; ENST00000579383.5; ENST00000584686.1; ENST00000578968.5; ENST00000438705.3; ENST00000585030.5
External Link	RMBase: m6A_site_756801
mod ID: M6ASITE080105		Click to Show/Hide the Full List
mod site	chr7:44984846-44984847:-		[5]
Sequence	GTGCTCATCTTAAAGGAAAAACTCATGGAAGAGGAAGGTGC
Motif Score	2.627720238
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000577700.5; ENST00000579383.5; ENST00000582727.1; ENST00000580458.5; ENST00000584327.5; ENST00000584686.1; ENST00000438705.3; ENST00000585030.5; ENST00000578968.5
External Link	RMBase: m6A_site_756802
mod ID: M6ASITE080106		Click to Show/Hide the Full List
mod site	chr7:44985099-44985100:-		[4]
Sequence	TGCTGTGCTCCAGGCTCAGTACAAATTTTATTTTATTATAC
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000579383.5; ENST00000438705.3; ENST00000580458.5; ENST00000577700.5; ENST00000584327.5; ENST00000582727.1; ENST00000585030.5; ENST00000584686.1; ENST00000578968.5
External Link	RMBase: m6A_site_756803
mod ID: M6ASITE080107		Click to Show/Hide the Full List
mod site	chr7:44985158-44985159:-		[4]
Sequence	CGCTGTGGAAGTTGTTTTGGACAATGCTGGTGTGAAAGGTG
Motif Score	3.643047619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000578968.5; ENST00000579383.5; ENST00000580458.5; ENST00000584686.1; ENST00000438705.3; ENST00000584327.5; ENST00000582727.1; ENST00000577700.5; ENST00000585030.5
External Link	RMBase: m6A_site_756804
mod ID: M6ASITE080108		Click to Show/Hide the Full List
mod site	chr7:44985303-44985304:-		[4]
Sequence	TAATGTGGTAGCCACTTGGCACACATGATTAAATTAAATTT
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000578968.5; ENST00000584686.1; ENST00000582727.1; ENST00000577700.5; ENST00000580458.5; ENST00000579383.5; ENST00000438705.3; ENST00000584327.5; ENST00000585030.5
External Link	RMBase: m6A_site_756805
mod ID: M6ASITE080109		Click to Show/Hide the Full List
mod site	chr7:44985382-44985383:-		[4]
Sequence	CAAGGTTATAGAAATTTCAGACAATGACTTCCTCCCTCCTG
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000579383.5; ENST00000384215.1; ENST00000438705.3; ENST00000585030.5; ENST00000580458.5; ENST00000577700.5; ENST00000584686.1; ENST00000578968.5; ENST00000584327.5; ENST00000582727.1
External Link	RMBase: m6A_site_756806
mod ID: M6ASITE080110		Click to Show/Hide the Full List
mod site	chr7:44985698-44985699:-		[4]
Sequence	ATAAGGTTATCTCTTCCAAGACACCTTCCCTTCTTCCTCAG
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000438705.3; ENST00000582727.1; ENST00000579383.5; ENST00000578968.5; ENST00000584327.5; ENST00000585030.5; ENST00000584686.1; ENST00000577700.5; ENST00000580458.5; ENST00000580528.1
External Link	RMBase: m6A_site_756807
mod ID: M6ASITE080111		Click to Show/Hide the Full List
mod site	chr7:44985828-44985829:-		[4]
Sequence	AGGCAGTATTTATATTAACTACATGATGATAAGGATGTTTC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000578968.5; ENST00000584327.5; ENST00000580458.5; ENST00000580528.1; ENST00000585030.5; ENST00000584686.1; ENST00000438705.3; ENST00000582727.1; ENST00000577700.5; ENST00000579383.5
External Link	RMBase: m6A_site_756808
mod ID: M6ASITE080112		Click to Show/Hide the Full List
mod site	chr7:44985873-44985874:-		[4]
Sequence	TGATTTCTGAGCCGTAAGATACATGAGAAAAAAATGAAGGG
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000580458.5; ENST00000585030.5; ENST00000582727.1; ENST00000577700.5; ENST00000578968.5; ENST00000584686.1; ENST00000580528.1; ENST00000579383.5; ENST00000438705.3; ENST00000584327.5
External Link	RMBase: m6A_site_756809
mod ID: M6ASITE080113		Click to Show/Hide the Full List
mod site	chr7:44986219-44986220:-		[6]
Sequence	AGGCATGGGGTGGCGTGTAGACCTGCCGCAAGAGAGGCTGT
Motif Score	2.876744048
Cell/Tissue List	HeLa; peripheral-blood; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000580528.1; ENST00000577700.5; ENST00000580458.5; ENST00000582727.1; ENST00000579383.5; ENST00000585030.5; ENST00000584327.5; ENST00000578968.5; ENST00000438705.3; ENST00000584686.1
External Link	RMBase: m6A_site_756810
mod ID: M6ASITE080114		Click to Show/Hide the Full List
mod site	chr7:44986250-44986251:-		[6]
Sequence	GGGACGTGTGGTCAGGAGGGACCTCACCGGAAGGCATGGGG
Motif Score	3.622404762
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000578968.5; ENST00000580458.5; ENST00000584327.5; ENST00000579383.5; ENST00000580528.1; ENST00000577700.5; ENST00000584686.1; ENST00000585030.5; ENST00000582727.1; ENST00000438705.3
External Link	RMBase: m6A_site_756811
mod ID: M6ASITE080115		Click to Show/Hide the Full List
mod site	chr7:44986287-44986288:-		[6]
Sequence	CTTCTGCATGACCTGGGTGGACCCCAGTAGGTGGGATGGGA
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000582727.1; ENST00000577700.5; ENST00000584686.1; ENST00000580528.1; ENST00000578968.5; ENST00000580458.5; ENST00000438705.3; ENST00000585030.5; ENST00000579383.5; ENST00000584327.5
External Link	RMBase: m6A_site_756812
mod ID: M6ASITE080116		Click to Show/Hide the Full List
mod site	chr7:44986634-44986635:-		[6]
Sequence	GCGTCAGTCTTGGCTGGCAGACCTGTACTCCGTACTCCGTA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293A-TOA; TIME
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000580458.5; ENST00000585030.5; ENST00000580528.1; ENST00000578968.5; ENST00000579383.5; ENST00000577700.5; ENST00000584686.1; ENST00000582727.1
External Link	RMBase: m6A_site_756813
mod ID: M6ASITE080117		Click to Show/Hide the Full List
mod site	chr7:44986692-44986693:-		[6]
Sequence	ACGCACGGCTTCGGGGCGGGACTACGCGGTGACGTCGAGGT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000578968.5; ENST00000580528.1
External Link	RMBase: m6A_site_756814

Ref 1	Phase I dose escalation clinical trial of adenovirus vector carrying osteocalcin promoter-driven herpes simplex virus thymidine kinase in localized and metastatic hormone-refractory prostate cancer. Hum Gene Ther. 2003 Feb 10;14(3):227-41. doi: 10.1089/10430340360535788.
Ref 2	Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping. Nature. 2020 Jul;583(7817):638-643. doi: 10.1038/s41586-020-2418-2. Epub 2020 Jun 17.
Ref 3	NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells. Nucleic Acids Res. 2023 Sep 8;51(16):8514-8531. doi: 10.1093/nar/gkad628.
Ref 4	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 5	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 6	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

Visitor Map