m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR01003)

Target Name	Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPA)
Synonyms	SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MyD-1 antigen; Signal-regulatory protein alpha-1; Sirp-alpha-1; Signal-regulatory protein alpha-2; Sirp-alpha-2; Signal-regulatory protein alpha-3; Sirp-alpha-3; p84; CD antigen CD172a Click to Show/Hide
Gene Name	SIRPA
Chromosomal Location	20p13
Function	Immunoglobulin-like cell surface receptor for CD47. Acts as docking protein and induces translocation of PTPN6, PTPN11 and other binding partners from the cytosol to the plasma membrane. Supports adhesion of cerebellar neurons, neurite outgrowth and glial cell attachment. May play a key role in intracellular signaling during synaptogenesis and in synaptic function (By similarity). Involved in the negative regulation of receptor tyrosine kinase-coupled cellular responses induced by cell adhesion, growth factors or insulin. Mediates negative regulation of phagocytosis, mast cell activation and dendritic cell activation. CD47 binding prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. Plays a role in antiviral immunity and limits new world arenavirus infection by decreasing virus internalization (By similarity). Receptor for THBS1 (PubMed:24511121). Interaction with THBS1 stimulates phosphorylation of SIRPA (By similarity). In response to THBS1, involved in ROS signaling in non-phagocytic cells, stimulating NADPH oxidase-derived ROS production (PubMed:24511121). Click to Show/Hide
Gene ID	140885
Uniprot ID	SHPS1_HUMAN
HGNC ID	HGNC:9662
KEGG ID	hsa:140885

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Non-coding RNA

m6A Regulator: Fat mass and obesity-associated protein (FTO)

Regulator Info

In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05248		Crosstalk Info
Epigenetic Regulator	hsa-miR-607
Regulated Target	FTO alpha-ketoglutarate dependent dioxygenase (FTO)
Crosstalk relationship	ncRNA → m6A
Disease	Non-small cell lung cancer	Disease Info
Drug	Gefitinib	Drug Info
Crosstalk ID: M6ACROT05262		Crosstalk Info
Epigenetic Regulator	hsa_circ_0072309 (Circ_LIFR)
Regulated Target	hsa-miR-607
Crosstalk relationship	ncRNA → m6A
Disease	Non-small cell lung cancer	Disease Info
Drug	Gefitinib	Drug Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR01003)

Tyrosine-protein phosphatase non-receptor type substrate 1 (SIRPA)

Adenosine-to-Inosine editing (A-to-I)

In total 8 m6A sequence/site(s) in this target gene
mod ID: A2ISITE010326		Click to Show/Hide the Full List
mod site	chr20:1902497-1902498:+		[2]
Sequence	AATATTTTTGAGCACCTACTATGTGCCAGGGATGGCTCTAG
Transcript ID List	ENST00000358771.4; ENST00000400068.7; ENST00000622179.4; ENST00000356025.7
External Link	RMBase: RNA-editing_site_85020
mod ID: A2ISITE010327		Click to Show/Hide the Full List
mod site	chr20:1919304-1919305:+		[2]
Sequence	AAGTTTTTAATTAATCCAGAAGATTCTAATACAGAGTCAGG
Transcript ID List	ENST00000400068.7; ENST00000358771.4; ENST00000356025.7; ENST00000622179.4
External Link	RMBase: RNA-editing_site_85021
mod ID: A2ISITE010328		Click to Show/Hide the Full List
mod site	chr20:1920592-1920593:+		[2]
Sequence	CTCCACACTTGGTGATCTTTAGTGTCTATCTAAAACTGACA
Transcript ID List	ENST00000622179.4; ENST00000356025.7; ENST00000400068.7; ENST00000358771.4
External Link	RMBase: RNA-editing_site_85022
mod ID: A2ISITE010329		Click to Show/Hide the Full List
mod site	chr20:1923780-1923781:+		[2]
Sequence	TGGCTGTGTGACCTTGGACAAGTCAGTGCCTCTCTCTGGGC
Transcript ID List	ENST00000622179.4; rmsk_5049233; ENST00000358771.4; ENST00000400068.7; ENST00000356025.7
External Link	RMBase: RNA-editing_site_85023
mod ID: A2ISITE010330		Click to Show/Hide the Full List
mod site	chr20:1926672-1926673:+		[2]
Sequence	CAGACCTCATGGGTGACATTACTAACCCCACTTTACAGATG
Transcript ID List	ENST00000622179.4; ENST00000400068.7; ENST00000356025.7; ENST00000358771.4
External Link	RMBase: RNA-editing_site_85024
mod ID: A2ISITE010331		Click to Show/Hide the Full List
mod site	chr20:1933692-1933693:+		[2]
Sequence	GAGCCAAGCACTCATGCCAAATCCATTAATAACCCTGCTGC
Transcript ID List	ENST00000622179.4; ENST00000358771.4; ENST00000400068.7; ENST00000356025.7
External Link	RMBase: RNA-editing_site_85025
mod ID: A2ISITE010332		Click to Show/Hide the Full List
mod site	chr20:1936065-1936066:+		[2]
Sequence	TTCCCAAGCAGGGTTGTGGTAAGAGTGGATGGGGTGATCTA
Transcript ID List	rmsk_5049262; ENST00000356025.7; ENST00000622179.4; ENST00000400068.7; ENST00000358771.4
External Link	RMBase: RNA-editing_site_85026
mod ID: A2ISITE010333		Click to Show/Hide the Full List
mod site	chr20:1936379-1936380:+		[2]
Sequence	TCTAAACGCTTTACCTGGATAATCTCATTCCATCCTCACAG
Transcript ID List	ENST00000622179.4; ENST00000356025.7; ENST00000400068.7; ENST00000358771.4
External Link	RMBase: RNA-editing_site_85027

5-methylcytidine (m5C)

In total 2 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002568		Click to Show/Hide the Full List
mod site	chr20:1894605-1894606:+
Sequence	CTTCTGAACGGGCACGCTGTCGGAGCCGGAGGCTCGTCTAG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000622179.4; ENST00000400068.7
External Link	RMBase: m5C_site_28313
mod ID: M5CSITE002569		Click to Show/Hide the Full List
mod site	chr20:1927511-1927512:+
Sequence	GCTAGAATCTGTTTTCAAGCCACGAAGGGCACTGATTGGGA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000622179.4; ENST00000356025.7; ENST00000358771.4; ENST00000400068.7
External Link	RMBase: m5C_site_28314

N6-methyladenosine (m6A)

In total 58 m6A sequence/site(s) in this target gene
mod ID: M6ASITE051102		Click to Show/Hide the Full List
mod site	chr20:1915257-1915258:+		[3]
Sequence	ACCAGGCCGGGAATTAATCTACAATCAAAAAGAAGGCCACT
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000356025.7; ENST00000622179.4; ENST00000400068.7; ENST00000358771.4
External Link	RMBase: m6A_site_520346
mod ID: M6ASITE051103		Click to Show/Hide the Full List
mod site	chr20:1921398-1921399:+		[4]
Sequence	GATGGTCCTTTTGTAGCCAAACCCTCTGCCCCCGTGGTATC
Motif Score	2.185083333
Cell/Tissue List	peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000622179.4; ENST00000356025.7; ENST00000358771.4; ENST00000400068.7
External Link	RMBase: m6A_site_520347
mod ID: M6ASITE051104		Click to Show/Hide the Full List
mod site	chr20:1921493-1921494:+		[4]
Sequence	CCACGGCTTCTCACCCAGAGACATCACCCTGAAATGGTTCA
Motif Score	2.897386905
Cell/Tissue List	peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000356025.7; ENST00000400068.7; ENST00000358771.4; ENST00000622179.4
External Link	RMBase: m6A_site_520348
mod ID: M6ASITE051105		Click to Show/Hide the Full List
mod site	chr20:1921535-1921536:+		[5]
Sequence	AAATGGGAATGAGCTCTCAGACTTCCAGACCAACGTGGACC
Motif Score	3.319380952
Cell/Tissue List	CD4T; peripheral-blood; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000622179.4; ENST00000356025.7; ENST00000358771.4; ENST00000400068.7
External Link	RMBase: m6A_site_520349
mod ID: M6ASITE051106		Click to Show/Hide the Full List
mod site	chr20:1921543-1921544:+		[5]
Sequence	ATGAGCTCTCAGACTTCCAGACCAACGTGGACCCCGTAGGA
Motif Score	2.876744048
Cell/Tissue List	CD4T; peripheral-blood; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000622179.4; ENST00000400068.7; ENST00000358771.4; ENST00000356025.7
External Link	RMBase: m6A_site_520350
mod ID: M6ASITE051107		Click to Show/Hide the Full List
mod site	chr20:1921553-1921554:+		[5]
Sequence	AGACTTCCAGACCAACGTGGACCCCGTAGGAGAGAGCGTGT
Motif Score	3.622404762
Cell/Tissue List	CD4T; peripheral-blood; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000356025.7; ENST00000358771.4; ENST00000400068.7; ENST00000622179.4
External Link	RMBase: m6A_site_520351
mod ID: M6ASITE051108		Click to Show/Hide the Full List
mod site	chr20:1921670-1921671:+		[4]
Sequence	CCACGTCACCTTGCAGGGGGACCCTCTTCGTGGGACTGCCA
Motif Score	3.622404762
Cell/Tissue List	HEK293T; peripheral-blood
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000400068.7; ENST00000622179.4; ENST00000356025.7; ENST00000358771.4
External Link	RMBase: m6A_site_520352
mod ID: M6ASITE051109		Click to Show/Hide the Full List
mod site	chr20:1921684-1921685:+		[4]
Sequence	AGGGGGACCCTCTTCGTGGGACTGCCAACTTGTCTGAGACC
Motif Score	4.065041667
Cell/Tissue List	HEK293T; peripheral-blood
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000400068.7; ENST00000358771.4; ENST00000622179.4; ENST00000356025.7
External Link	RMBase: m6A_site_520353
mod ID: M6ASITE051110		Click to Show/Hide the Full List
mod site	chr20:1921702-1921703:+		[6]
Sequence	GGACTGCCAACTTGTCTGAGACCATCCGAGGTAGAAGACCC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; peripheral-blood; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358771.4; ENST00000356025.7; ENST00000400068.7; ENST00000622179.4
External Link	RMBase: m6A_site_520354
mod ID: M6ASITE051111		Click to Show/Hide the Full List
mod site	chr20:1922357-1922358:+		[6]
Sequence	ACAGCCCGTGAGGGCAGAGAACCAGGTGAATGTCACCTGCC
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; MM6; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000622179.4; ENST00000358771.4; ENST00000356025.7; ENST00000400068.7
External Link	RMBase: m6A_site_520355
mod ID: M6ASITE051112		Click to Show/Hide the Full List
mod site	chr20:1922403-1922404:+		[6]
Sequence	AGGAAGTTCTACCCCCAGAGACTACAGCTGACCTGGTTGGA
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1B; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358771.4; ENST00000400068.7; ENST00000622179.4; ENST00000356025.7
External Link	RMBase: m6A_site_520356
mod ID: M6ASITE051113		Click to Show/Hide the Full List
mod site	chr20:1922443-1922444:+		[6]
Sequence	AGAATGGAAACGTGTCCCGGACAGAAACGGCCTCAACCGTT
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; hESC-HEK293T; H1B; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq; miCLIP
Transcript ID List	ENST00000400068.7; ENST00000622179.4; ENST00000358771.4; ENST00000356025.7
External Link	RMBase: m6A_site_520357
mod ID: M6ASITE051114		Click to Show/Hide the Full List
mod site	chr20:1922471-1922472:+		[6]
Sequence	GGCCTCAACCGTTACAGAGAACAAGGATGGTACCTACAACT
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1B; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000356025.7; ENST00000400068.7; ENST00000622179.4; ENST00000358771.4
External Link	RMBase: m6A_site_520358
mod ID: M6ASITE051115		Click to Show/Hide the Full List
mod site	chr20:1924766-1924767:+		[3]
Sequence	TTCCATGTGGTCCCTAGAGAACACTGGATCTAATGAACGGA
Motif Score	2.951386905
Cell/Tissue List	hESC-HEK293T; MM6; peripheral-blood; HEC-1-A
Seq Type List	MAZTER-seq; m6A-seq
Transcript ID List	ENST00000400068.7; ENST00000358771.4; ENST00000356025.7; ENST00000622179.4
External Link	RMBase: m6A_site_520359
mod ID: M6ASITE051116		Click to Show/Hide the Full List
mod site	chr20:1924787-1924788:+		[7]
Sequence	CACTGGATCTAATGAACGGAACATCTATATTGTGGTGGGTG
Motif Score	2.951386905
Cell/Tissue List	MM6; peripheral-blood; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000358771.4; ENST00000400068.7; ENST00000622179.4; ENST00000356025.7
External Link	RMBase: m6A_site_520360
mod ID: M6ASITE051117		Click to Show/Hide the Full List
mod site	chr20:1924866-1924867:+		[8]
Sequence	CTCTACCTCGTCCGAATCAGACAGAAGAAAGGTGGGTGCAT
Motif Score	2.897386905
Cell/Tissue List	CD34; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000400068.7; ENST00000622179.4; ENST00000356025.7; ENST00000358771.4
External Link	RMBase: m6A_site_520361
mod ID: M6ASITE051118		Click to Show/Hide the Full List
mod site	chr20:1937334-1937335:+		[3]
Sequence	TCCAGGACACAAATGATATCACATATGCAGACCTGAACCTG
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000358771.4; ENST00000400068.7; ENST00000356025.7; ENST00000622179.4
External Link	RMBase: m6A_site_520362
mod ID: M6ASITE051119		Click to Show/Hide the Full List
mod site	chr20:1937344-1937345:+		[8]
Sequence	AAATGATATCACATATGCAGACCTGAACCTGCCCAAGGGGA
Motif Score	2.876744048
Cell/Tissue List	CD34; MT4; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000622179.4; ENST00000356025.7; ENST00000400068.7; ENST00000358771.4
External Link	RMBase: m6A_site_520363
mod ID: M6ASITE051120		Click to Show/Hide the Full List
mod site	chr20:1937350-1937351:+		[8]
Sequence	TATCACATATGCAGACCTGAACCTGCCCAAGGGGAAGAAGC
Motif Score	2.930744048
Cell/Tissue List	CD34; MT4; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000400068.7; ENST00000356025.7; ENST00000358771.4; ENST00000622179.4
External Link	RMBase: m6A_site_520364
mod ID: M6ASITE051121		Click to Show/Hide the Full List
mod site	chr20:1937395-1937396:+		[3]
Sequence	TCCCCAGGCTGCGGAGCCCAACAACCACACGGAGTATGCCA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000400068.7; ENST00000356025.7; ENST00000622179.4; ENST00000358771.4
External Link	RMBase: m6A_site_520365
mod ID: M6ASITE051122		Click to Show/Hide the Full List
mod site	chr20:1937401-1937402:+		[3]
Sequence	GGCTGCGGAGCCCAACAACCACACGGAGTATGCCAGCATTC
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000622179.4; ENST00000358771.4; ENST00000356025.7; ENST00000400068.7
External Link	RMBase: m6A_site_520366
mod ID: M6ASITE051123		Click to Show/Hide the Full List
mod site	chr20:1937424-1937425:+		[9]
Sequence	CGGAGTATGCCAGCATTCAGACCAGCCCGCAGCCCGCGTCG
Motif Score	2.876744048
Cell/Tissue List	HEK293T; U2OS; MM6; Huh7; TIME; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000358771.4; ENST00000400068.7; ENST00000356025.7; ENST00000622179.4
External Link	RMBase: m6A_site_520367
mod ID: M6ASITE051124		Click to Show/Hide the Full List
mod site	chr20:1937449-1937450:+		[3]
Sequence	CCCGCAGCCCGCGTCGGAGGACACCCTCACCTATGCTGACC
Motif Score	3.643047619
Cell/Tissue List	HEK293T; hESC-HEK293T; U2OS; MM6; Huh7; peripheral-blood; HEK293A-TOA; TIME; iSLK; HEC-1-A
Seq Type List	MeRIP-seq; MAZTER-seq; m6A-seq
Transcript ID List	ENST00000356025.7; ENST00000400068.7; ENST00000622179.4; ENST00000358771.4
External Link	RMBase: m6A_site_520368
mod ID: M6ASITE051125		Click to Show/Hide the Full List
mod site	chr20:1937473-1937474:+		[10]
Sequence	CCTCACCTATGCTGACCTGGACATGGTCCACCTCAACCGGA
Motif Score	3.643047619
Cell/Tissue List	HEK293T; brain; U2OS; MM6; Huh7; peripheral-blood; HEK293A-TOA; TIME; iSLK; HEC-1-A
Seq Type List	MeRIP-seq; m6A-REF-seq; m6A-seq
Transcript ID List	ENST00000358771.4; ENST00000400068.7; ENST00000356025.7; ENST00000622179.4
External Link	RMBase: m6A_site_520369
mod ID: M6ASITE051126		Click to Show/Hide the Full List
mod site	chr20:1937493-1937494:+		[11]
Sequence	ACATGGTCCACCTCAACCGGACCCCCAAGCAGCCGGCCCCC
Motif Score	3.622404762
Cell/Tissue List	HepG2; HEK293T; U2OS; MM6; Huh7; peripheral-blood; HEK293A-TOA; iSLK; TIME; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000400068.7; ENST00000358771.4; ENST00000622179.4; ENST00000356025.7
External Link	RMBase: m6A_site_520370
mod ID: M6ASITE051127		Click to Show/Hide the Full List
mod site	chr20:1937573-1937574:+		[12]
Sequence	GTCCCGAGGAAGTGAATGGGACCGTGGTTTGCTCTAGCACC
Motif Score	3.622404762
Cell/Tissue List	HepG2; HEK293T; A549; U2OS; MM6; Huh7; CD4T; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358771.4; ENST00000622179.4; ENST00000356025.7; ENST00000400068.7
External Link	RMBase: m6A_site_520371
mod ID: M6ASITE051128		Click to Show/Hide the Full List
mod site	chr20:1937640-1937641:+		[10]
Sequence	AGGGAGCCGCCGTGATGAGCACAGCCAACCCAGTTCCCGGA
Motif Score	2.830589286
Cell/Tissue List	brain
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000400068.7; ENST00000358771.4; ENST00000622179.4; ENST00000356025.7
External Link	RMBase: m6A_site_520372
mod ID: M6ASITE051129		Click to Show/Hide the Full List
mod site	chr20:1937686-1937687:+		[12]
Sequence	GGGGCGGTGCAGGCTCTGGGACCCAGGGGCCAGGGTGGCTC
Motif Score	3.622404762
Cell/Tissue List	HepG2; HEK293T; HeLa; A549; U2OS; fibroblasts; GM12878; MM6; Huh7; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358771.4; ENST00000400068.7; ENST00000622179.4; ENST00000356025.7
External Link	RMBase: m6A_site_520373
mod ID: M6ASITE051130		Click to Show/Hide the Full List
mod site	chr20:1937793-1937794:+		[13]
Sequence	TGCCACATACCTGGAGGCTGACGTTGCCAAACCAGCCAGGG
Motif Score	2.833690476
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000358771.4; ENST00000400068.7; ENST00000622179.4; ENST00000356025.7
External Link	RMBase: m6A_site_520374
mod ID: M6ASITE051131		Click to Show/Hide the Full List
mod site	chr20:1937803-1937804:+		[6]
Sequence	CTGGAGGCTGACGTTGCCAAACCAGCCAGGGAACCAACCTG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000622179.4; ENST00000400068.7; ENST00000356025.7; ENST00000358771.4
External Link	RMBase: m6A_site_520375
mod ID: M6ASITE051132		Click to Show/Hide the Full List
mod site	chr20:1937815-1937816:+		[6]
Sequence	GTTGCCAAACCAGCCAGGGAACCAACCTGGGAAGTGGCCAG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000356025.7; ENST00000358771.4; ENST00000400068.7; ENST00000622179.4
External Link	RMBase: m6A_site_520376
mod ID: M6ASITE051133		Click to Show/Hide the Full List
mod site	chr20:1937837-1937838:+		[6]
Sequence	CAACCTGGGAAGTGGCCAGAACTGCCTGGGGTCCAAGAACT
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000358771.4; ENST00000622179.4; ENST00000400068.7; ENST00000356025.7
External Link	RMBase: m6A_site_520377
mod ID: M6ASITE051134		Click to Show/Hide the Full List
mod site	chr20:1937855-1937856:+		[6]
Sequence	GAACTGCCTGGGGTCCAAGAACTCTTGTGCCTCCGTCCATC
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000358771.4; ENST00000622179.4; ENST00000400068.7; ENST00000356025.7
External Link	RMBase: m6A_site_520378
mod ID: M6ASITE051135		Click to Show/Hide the Full List
mod site	chr20:1937894-1937895:+		[6]
Sequence	TCACCATGTGGGTTTTGAAGACCCTCGACTGCCTCCCCGAT
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000356025.7; ENST00000358771.4; ENST00000622179.4; ENST00000400068.7
External Link	RMBase: m6A_site_520379
mod ID: M6ASITE051136		Click to Show/Hide the Full List
mod site	chr20:1937901-1937902:+		[14]
Sequence	GTGGGTTTTGAAGACCCTCGACTGCCTCCCCGATGCTCCGA
Motif Score	3.287565476
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000358771.4; ENST00000356025.7; ENST00000622179.4; ENST00000400068.7
External Link	RMBase: m6A_site_520380
mod ID: M6ASITE051137		Click to Show/Hide the Full List
mod site	chr20:1938065-1938066:+		[12]
Sequence	AGATTTCCCCTTTAGATCAAACTGCCCCTTCCATGGAAAAG
Motif Score	2.627720238
Cell/Tissue List	HepG2; HEK293T; HeLa; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000622179.4; ENST00000356025.7; ENST00000400068.7; ENST00000358771.4
External Link	RMBase: m6A_site_520381
mod ID: M6ASITE051138		Click to Show/Hide the Full List
mod site	chr20:1938096-1938097:+		[12]
Sequence	CATGGAAAAGCTGGAAAAAAACTCTGGAACCCATATCCAGG
Motif Score	2.627720238
Cell/Tissue List	HepG2; HEK293T; HeLa; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000622179.4; ENST00000400068.7; ENST00000358771.4; ENST00000356025.7
External Link	RMBase: m6A_site_520382
mod ID: M6ASITE051139		Click to Show/Hide the Full List
mod site	chr20:1938104-1938105:+		[12]
Sequence	AGCTGGAAAAAAACTCTGGAACCCATATCCAGGCTTGGTGA
Motif Score	2.930744048
Cell/Tissue List	HepG2; HEK293T; HeLa; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000622179.4; ENST00000356025.7; ENST00000358771.4; ENST00000400068.7
External Link	RMBase: m6A_site_520383
mod ID: M6ASITE051140		Click to Show/Hide the Full List
mod site	chr20:1938195-1938196:+		[6]
Sequence	GAGTCCTGGAGGAGGAGAGGACCCCTCCCAAAGGACTGGAG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000400068.7; ENST00000356025.7; ENST00000622179.4; ENST00000358771.4
External Link	RMBase: m6A_site_520384
mod ID: M6ASITE051141		Click to Show/Hide the Full List
mod site	chr20:1938209-1938210:+		[6]
Sequence	GAGAGGACCCCTCCCAAAGGACTGGAGACAAAACCCTCTGC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000622179.4; ENST00000358771.4; ENST00000400068.7; ENST00000356025.7
External Link	RMBase: m6A_site_520385
mod ID: M6ASITE051142		Click to Show/Hide the Full List
mod site	chr20:1938216-1938217:+		[6]
Sequence	CCCCTCCCAAAGGACTGGAGACAAAACCCTCTGCTTCCTTG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; brain; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; m6A-REF-seq; MAZTER-seq; miCLIP
Transcript ID List	ENST00000358771.4; ENST00000400068.7; ENST00000622179.4; ENST00000356025.7
External Link	RMBase: m6A_site_520386
mod ID: M6ASITE051143		Click to Show/Hide the Full List
mod site	chr20:1938221-1938222:+		[6]
Sequence	CCCAAAGGACTGGAGACAAAACCCTCTGCTTCCTTGGGTCC
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000622179.4; ENST00000358771.4; ENST00000400068.7; ENST00000356025.7
External Link	RMBase: m6A_site_520387
mod ID: M6ASITE051144		Click to Show/Hide the Full List
mod site	chr20:1938249-1938250:+		[6]
Sequence	CTTCCTTGGGTCCCTCCAAGACTCCCTGGGGCCCAACTGTG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358771.4; ENST00000622179.4; ENST00000400068.7; ENST00000356025.7
External Link	RMBase: m6A_site_520388
mod ID: M6ASITE051145		Click to Show/Hide the Full List
mod site	chr20:1938283-1938284:+		[12]
Sequence	AACTGTGTTGCTCCACCCGGACCCATCTCTCCCTTCTAGAC
Motif Score	3.622404762
Cell/Tissue List	HepG2; HEK293T; HeLa; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000622179.4; ENST00000400068.7; ENST00000358771.4; ENST00000356025.7
External Link	RMBase: m6A_site_520389
mod ID: M6ASITE051146		Click to Show/Hide the Full List
mod site	chr20:1938302-1938303:+		[12]
Sequence	GACCCATCTCTCCCTTCTAGACCTGAGCTTGCCCCTCCAGC
Motif Score	2.876744048
Cell/Tissue List	HepG2; HEK293T; HeLa; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000400068.7; ENST00000358771.4; ENST00000356025.7; ENST00000622179.4
External Link	RMBase: m6A_site_520390
mod ID: M6ASITE051147		Click to Show/Hide the Full List
mod site	chr20:1938335-1938336:+		[3]
Sequence	CCTCCAGCTAGCACTAAGCAACATCTCGCTGTGGACGCCTG
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000358771.4; ENST00000622179.4; ENST00000400068.7; ENST00000356025.7
External Link	RMBase: m6A_site_520391
mod ID: M6ASITE051148		Click to Show/Hide the Full List
mod site	chr20:1938392-1938393:+		[12]
Sequence	GTGAAACGTGCAATCTTGAAACTGAGGTGTTAGAAAACTTG
Motif Score	2.627720238
Cell/Tissue List	HepG2; HEK293T; HeLa; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; MM6; Huh7; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358771.4; ENST00000356025.7; ENST00000622179.4; ENST00000400068.7
External Link	RMBase: m6A_site_520392
mod ID: M6ASITE051149		Click to Show/Hide the Full List
mod site	chr20:1938408-1938409:+		[12]
Sequence	TGAAACTGAGGTGTTAGAAAACTTGATCTGTGGTGTTTTGT
Motif Score	2.627720238
Cell/Tissue List	HepG2; HEK293T; HeLa; A549; U2OS; H1B; hESCs; fibroblasts; GM12878; MM6; Huh7; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358771.4; ENST00000356025.7; ENST00000622179.4; ENST00000400068.7
External Link	RMBase: m6A_site_520393
mod ID: M6ASITE051150		Click to Show/Hide the Full List
mod site	chr20:1938447-1938448:+		[12]
Sequence	GTTTTGTTTTTTTTCTTAAAACAACAGCAACGTGATCTTGG
Motif Score	2.20572619
Cell/Tissue List	HepG2; HEK293T; A549; hESC-HEK293T; U2OS; hESCs; fibroblasts; GM12878; MM6; Huh7; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000400068.7; ENST00000356025.7; ENST00000358771.4; ENST00000622179.4
External Link	RMBase: m6A_site_520394
mod ID: M6ASITE051151		Click to Show/Hide the Full List
mod site	chr20:1938559-1938560:+		[12]
Sequence	GGGATTTTCTTACAGCGAAGACTTGAGTTCCTCCAAGTCCC
Motif Score	3.319380952
Cell/Tissue List	HepG2; HEK293T; A549; U2OS; H1A; MM6; Huh7; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000400068.7; ENST00000356025.7; ENST00000622179.4; ENST00000358771.4
External Link	RMBase: m6A_site_520395
mod ID: M6ASITE051152		Click to Show/Hide the Full List
mod site	chr20:1938583-1938584:+		[12]
Sequence	GAGTTCCTCCAAGTCCCAGAACCCCAAGAATGGGCAAGAAG
Motif Score	2.930744048
Cell/Tissue List	HepG2; HEK293T; A549; U2OS; H1A; MM6; Huh7; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000622179.4; ENST00000400068.7; ENST00000358771.4; ENST00000356025.7
External Link	RMBase: m6A_site_520396
mod ID: M6ASITE051153		Click to Show/Hide the Full List
mod site	chr20:1938628-1938629:+		[12]
Sequence	AGGTCAGCCACTCCCTGGAGACACAGCCTTCTGGCTGGGAC
Motif Score	2.897386905
Cell/Tissue List	HepG2; HEK293T; A549; U2OS; H1B; H1A; GM12878; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000622179.4; ENST00000356025.7; ENST00000400068.7; ENST00000358771.4
External Link	RMBase: m6A_site_520397
mod ID: M6ASITE051154		Click to Show/Hide the Full List
mod site	chr20:1938647-1938648:+		[12]
Sequence	GACACAGCCTTCTGGCTGGGACTGACTTGGCCATGTTCTCA
Motif Score	4.065041667
Cell/Tissue List	HepG2; HEK293T; HeLa; A549; U2OS; H1B; H1A; hNPCs; GM12878; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000622179.4; ENST00000358771.4; ENST00000400068.7; ENST00000356025.7
External Link	RMBase: m6A_site_520398
mod ID: M6ASITE051155		Click to Show/Hide the Full List
mod site	chr20:1938774-1938775:+		[12]
Sequence	GACAGTGCAGTCTTATCGAGACCCAATGCCTCAGTCTGCTC
Motif Score	2.876744048
Cell/Tissue List	HepG2; HEK293T; A549; U2OS; MM6; Huh7; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000358771.4; ENST00000622179.4; ENST00000400068.7; ENST00000356025.7
External Link	RMBase: m6A_site_520399
mod ID: M6ASITE051156		Click to Show/Hide the Full List
mod site	chr20:1938822-1938823:+		[3]
Sequence	AAGTGGGGATAGTGAAGATGACACCCCTCCCCACCACCTCT
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T; A549
Seq Type List	MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000358771.4; ENST00000356025.7; rmsk_5049266; ENST00000400068.7; ENST00000622179.4
External Link	RMBase: m6A_site_520400
mod ID: M6ASITE051157		Click to Show/Hide the Full List
mod site	chr20:1938859-1938860:+		[15]
Sequence	CTCTCATAAGCACTTTAGGAACACACAGAGGGTAGGGATAG
Motif Score	2.951386905
Cell/Tissue List	A549; iSLK
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000358771.4; ENST00000356025.7; ENST00000622179.4; ENST00000400068.7
External Link	RMBase: m6A_site_520401
mod ID: M6ASITE051158		Click to Show/Hide the Full List
mod site	chr20:1940168-1940169:+		[16]
Sequence	TTGTAGCTGTGGGAGTTCAAACAGCACCTCTTTGAGACTTG
Motif Score	2.20572619
Cell/Tissue List	iSLK
Seq Type List	MeRIP-seq
Transcript ID List	rmsk_5049267; ENST00000622179.4
External Link	RMBase: m6A_site_520402
mod ID: M6ASITE051159		Click to Show/Hide the Full List
mod site	chr20:1940184-1940185:+		[4]
Sequence	TCAAACAGCACCTCTTTGAGACTTGGGCCCCGCGTCGGCAC
Motif Score	3.319380952
Cell/Tissue List	peripheral-blood; iSLK
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	rmsk_5049267; ENST00000622179.4
External Link	RMBase: m6A_site_520403

Ref 1	Pharmacogenomics of statins: understanding susceptibility to adverse effects. Pharmgenomics Pers Med. 2016 Oct 3;9:97-106. doi: 10.2147/PGPM.S86013. eCollection 2016.
Ref 2	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 3	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 4	R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m(6)A/MYC/CEBPA Signaling. Cell. 2018 Jan 11;172(1-2):90-105.e23. doi: 10.1016/j.cell.2017.11.031. Epub 2017 Dec 14.
Ref 5	N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression. Elife. 2016 Jul 2;5:e15528. doi: 10.7554/eLife.15528.
Ref 6	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 7	FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N(6)-Methyladenosine RNA Demethylase. Cancer Cell. 2017 Jan 9;31(1):127-141. doi: 10.1016/j.ccell.2016.11.017. Epub 2016 Dec 22.
Ref 8	Suppression of m(6)A reader Ythdf2 promotes hematopoietic stem cell expansion. Cell Res. 2018 Sep;28(9):904-917. doi: 10.1038/s41422-018-0072-0. Epub 2018 Jul 31.
Ref 9	RNA-methylation-dependent RNA processing controls the speed of the circadian clock. Cell. 2013 Nov 7;155(4):793-806. doi: 10.1016/j.cell.2013.10.026.
Ref 10	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 11	Efficacy of MEK inhibition in patients with histiocytic neoplasms. Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.
Ref 12	Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13.
Ref 13	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 14	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 15	Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus. Nat Commun. 2019 Oct 9;10(1):4595. doi: 10.1038/s41467-019-12504-y.
Ref 16	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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