m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00758)

Target Name	Protein BTG2 (BTG2)
Synonyms	PC3; Protein BTG2 ; BTG family member 2 ; NGF-inducible anti-proliferative protein PC3 Click to Show/Hide
Gene Name	BTG2
Chromosomal Location	1q32.1
Family	BTG family
Function	Anti-proliferative protein; the function is mediated by association with deadenylase subunits of the CCR4-NOT complex. Activates mRNA deadenylation in a CNOT6 and CNOT7-dependent manner. In vitro can inhibit deadenylase activity of CNOT7 and CNOT8. Involved in cell cycle regulation. Could be involved in the growth arrest and differentiation of the neuronal precursors (By similarity). Modulates transcription regulation mediated by ESR1. Involved in mitochondrial depolarization and neurite outgrowth. Click to Show/Hide
Gene ID	7832
Uniprot ID	BTG2_HUMAN
HGNC ID	HGNC:1131
KEGG ID	hsa:7832

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

BTG2 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

Protein virilizer homolog (VIRMA) [WRITER]

Regulator Info

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	Knockdown of KIAA1429 significantly decreased the m6A levels of Protein BTG2 (BTG2) mRNA, leading to enhanced YTHDF2-dependent BTG2 mRNA stability and promoted the expression of BTG2; thus, participating in the tumorigenesis of LUAD.
Target Regulation	Up regulation
Responsed Disease	Lung adenocarcinoma		ICD-11: 2C25.0	Disease Info
In-vitro Model	A-549	Lung adenocarcinoma	Homo sapiens	CVCL_0023
	SPC-A1	Endocervical adenocarcinoma	Homo sapiens	CVCL_6955
	NCI-H1299	Lung large cell carcinoma	Homo sapiens	CVCL_0060
	HBE (Human bronchial epithelial cell line)
In-vivo Model	For the in vivo cell proliferation assay, A549 and SPCA1 cells were stably transfected with sh-Ctrl and sh-KIAA1429 using lentivirus (GeneChem, Shanghai, China). The cells were subcutaneously injected into either side of the posterior flanks of the mouse. The tumor volume was measured every few days (length×width2×0.5).

Lung cancer [ICD-11: 2C25]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[1]
Response Summary	Knockdown of KIAA1429 significantly decreased the m6A levels of Protein BTG2 (BTG2) mRNA, leading to enhanced YTHDF2-dependent BTG2 mRNA stability and promoted the expression of BTG2; thus, participating in the tumorigenesis of LUAD.
Responsed Disease	Lung adenocarcinoma [ICD-11: 2C25.0]
Target Regulator	Protein virilizer homolog (VIRMA)		WRITER	Regulator Info
Target Regulation	Up regulation
In-vitro Model	A-549	Lung adenocarcinoma	Homo sapiens	CVCL_0023
	SPC-A1	Endocervical adenocarcinoma	Homo sapiens	CVCL_6955
	NCI-H1299	Lung large cell carcinoma	Homo sapiens	CVCL_0060
	HBE (Human bronchial epithelial cell line)
In-vivo Model	For the in vivo cell proliferation assay, A549 and SPCA1 cells were stably transfected with sh-Ctrl and sh-KIAA1429 using lentivirus (GeneChem, Shanghai, China). The cells were subcutaneously injected into either side of the posterior flanks of the mouse. The tumor volume was measured every few days (length×width2×0.5).

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00758)

Protein BTG2 (BTG2)

N6-methyladenosine (m6A)

In total 62 m6A sequence/site(s) in this target gene
mod ID: M6ASITE076977		Click to Show/Hide the Full List
mod site	chr1:203305556-203305557:+		[2]
Sequence	AGGGTAACGCTGTCTTGTGGACCCGCACTTCCCACCCGAGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; HepG2; A549; HEK293T; H1A; H1B; fibroblasts; GM12878; LCLs; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73293
mod ID: M6ASITE076978		Click to Show/Hide the Full List
mod site	chr1:203305576-203305577:+		[2]
Sequence	ACCCGCACTTCCCACCCGAGACCTCTCACTGAGCCCGAGCC
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HepG2; A549; HEK293T; H1A; H1B; fibroblasts; GM12878; LCLs; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73294
mod ID: M6ASITE076979		Click to Show/Hide the Full List
mod site	chr1:203305624-203305625:+		[2]
Sequence	ACATGAGCCACGGGAAGGGAACCGACATGCTCCCGGAGATC
Motif Score	2.930744048
Cell/Tissue List	HeLa; CD34; HepG2; A549; HEK293T; H1A; H1B; fibroblasts; GM12878; LCLs; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73295
mod ID: M6ASITE076980		Click to Show/Hide the Full List
mod site	chr1:203305628-203305629:+		[3]
Sequence	GAGCCACGGGAAGGGAACCGACATGCTCCCGGAGATCGCCG
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73296
mod ID: M6ASITE076981		Click to Show/Hide the Full List
mod site	chr1:203305681-203305682:+		[2]
Sequence	TCCTCTCCAGCCTCCTGAGGACCCGGGGCTGCGTGAGCGAG
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73297
mod ID: M6ASITE076982		Click to Show/Hide the Full List
mod site	chr1:203305744-203305745:+		[4]
Sequence	GGGCGCTCCAGGAGGCACTCACAGGTGAGCGCATGCCGAGG
Motif Score	2.047297619
Cell/Tissue List	HEK293
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73298
mod ID: M6ASITE076983		Click to Show/Hide the Full List
mod site	chr1:203307113-203307114:+		[2]
Sequence	GTCTCCACAGAGCACTACAAACACCACTGGTTTCCCGAAAA
Motif Score	2.20572619
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73299
mod ID: M6ASITE076985		Click to Show/Hide the Full List
mod site	chr1:203307172-203307173:+		[5]
Sequence	CTACCGCTGCATTCGCATCAACCACAAGATGGACCCCATCA
Motif Score	2.153267857
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73300
mod ID: M6ASITE076986		Click to Show/Hide the Full List
mod site	chr1:203307175-203307176:+		[3]
Sequence	CCGCTGCATTCGCATCAACCACAAGATGGACCCCATCATCA
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73301
mod ID: M6ASITE076987		Click to Show/Hide the Full List
mod site	chr1:203307184-203307185:+		[2]
Sequence	TCGCATCAACCACAAGATGGACCCCATCATCAGCAGGGTGG
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; fibroblasts; GM12878; LCLs; CD8T; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73302
mod ID: M6ASITE076988		Click to Show/Hide the Full List
mod site	chr1:203307218-203307219:+		[2]
Sequence	AGGGTGGCCAGCCAGATCGGACTCAGCCAGCCCCAGCTGCA
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73303
mod ID: M6ASITE076989		Click to Show/Hide the Full List
mod site	chr1:203307274-203307275:+		[2]
Sequence	CGAGCTGACCCTGTGGGTGGACCCCTATGAGGTGTCCTACC
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73304
mod ID: M6ASITE076990		Click to Show/Hide the Full List
mod site	chr1:203307376-203307377:+		[2]
Sequence	TGGGCTCCTCACCTGCAAGAACCAAGTGCTGCTGGGCCGGA
Motif Score	2.930744048
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; MT4; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73305
mod ID: M6ASITE076991		Click to Show/Hide the Full List
mod site	chr1:203307412-203307413:+		[2]
Sequence	CCGGAGCAGCCCCTCCAAGAACTACGTGATGGCAGTCTCCA
Motif Score	3.373380952
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; CD8T; MT4; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73306
mod ID: M6ASITE076992		Click to Show/Hide the Full List
mod site	chr1:203307484-203307485:+		[3]
Sequence	GCCGTGCTCATGCTGCCGTGACAACAGGCCACCACATACCT
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T; A549
Seq Type List	MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73307
mod ID: M6ASITE076993		Click to Show/Hide the Full List
mod site	chr1:203307487-203307488:+		[3]
Sequence	GTGCTCATGCTGCCGTGACAACAGGCCACCACATACCTCAA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T; CD8T
Seq Type List	MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73308
mod ID: M6ASITE076994		Click to Show/Hide the Full List
mod site	chr1:203307507-203307508:+		[5]
Sequence	ACAGGCCACCACATACCTCAACCTGGGGAACTGTATTTTTA
Motif Score	2.153267857
Cell/Tissue List	CD8T; A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73309
mod ID: M6ASITE076996		Click to Show/Hide the Full List
mod site	chr1:203307516-203307517:+		[2]
Sequence	CACATACCTCAACCTGGGGAACTGTATTTTTAAATGAAGAG
Motif Score	3.373380952
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; fibroblasts; GM12878; LCLs; CD8T; MT4; MM6; Huh7; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq; DART-seq; m6A-CLIP/IP
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73310
mod ID: M6ASITE076997		Click to Show/Hide the Full List
mod site	chr1:203307580-203307581:+		[2]
Sequence	TTAAGAAAGGAGGAAAAGAAACCAAAAGTTTTTTTTAAGAA
Motif Score	2.185083333
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; hNPCs; fibroblasts; GM12878; LCLs; MT4; Huh7; CD4T; peripheral-blood; HEK293A-TOA; iSLK; TIME; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73311
mod ID: M6ASITE076998		Click to Show/Hide the Full List
mod site	chr1:203307658-203307659:+		[2]
Sequence	CCCAGGTGCCTTTGGAGAGAACTGTTGCGTGCTTGAGTCTG
Motif Score	3.373380952
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1B; hNPCs; fibroblasts; GM12878; LCLs; CD8T; MT4; MM6; Huh7; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; MSC; TREX; TIME; endometrial
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73312
mod ID: M6ASITE076999		Click to Show/Hide the Full List
mod site	chr1:203307723-203307724:+		[2]
Sequence	GGGGAGCTGTTAGGGGGTAGACCTAGCCAAGGAGAAGTGGG
Motif Score	2.876744048
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1B; hNPCs; fibroblasts; GM12878; LCLs; MT4; MM6; Huh7; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; TREX; TIME; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73313
mod ID: M6ASITE077000		Click to Show/Hide the Full List
mod site	chr1:203307805-203307806:+		[2]
Sequence	AGCAAGGTTAGCAACTGTGAACAGAGAGGTCGGGATTTGCC
Motif Score	2.951386905
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; H1B; hNPCs; fibroblasts; LCLs; MT4; MM6; Huh7; Jurkat; CD4T; peripheral-blood; HEK293A-TOA; TREX; TIME; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73314
mod ID: M6ASITE077001		Click to Show/Hide the Full List
mod site	chr1:203307877-203307878:+		[2]
Sequence	TCTCTGTCTCCCCCAGCCAGACACCTGCATCCCTGGCTCCT
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; hESC-HEK293T; H1B; A549; LCLs; Huh7; CD4T; HEK293A-TOA; TREX; iSLK; endometrial
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73315
mod ID: M6ASITE077002		Click to Show/Hide the Full List
mod site	chr1:203307925-203307926:+		[2]
Sequence	TCAGGGGCATTCATGCCTGGACTTAAACAATACTATGTTAT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; LCLs; A549; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq; DART-seq; m6A-CLIP/IP
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73316
mod ID: M6ASITE077003		Click to Show/Hide the Full List
mod site	chr1:203307931-203307932:+		[2]
Sequence	GCATTCATGCCTGGACTTAAACAATACTATGTTATCTTTTC
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2; HEK293T; hESC-HEK293T; LCLs; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq; DART-seq; MAZTER-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73317
mod ID: M6ASITE077004		Click to Show/Hide the Full List
mod site	chr1:203308039-203308040:+		[6]
Sequence	CTGCTTTTCTTGAAATCATGACTTGTTTCTAATTCTACCCT
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73318
mod ID: M6ASITE077005		Click to Show/Hide the Full List
mod site	chr1:203308132-203308133:+		[7]
Sequence	CTGAGGGGGGGGAGGAGGGAACTGGAGGTTATTGGGGTTAG
Motif Score	3.373380952
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73319
mod ID: M6ASITE077006		Click to Show/Hide the Full List
mod site	chr1:203308164-203308165:+		[7]
Sequence	TGGGGTTAGGATGGAAGGGAACTCTGCACAAAACCTTTGCT
Motif Score	3.373380952
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73320
mod ID: M6ASITE077007		Click to Show/Hide the Full List
mod site	chr1:203308171-203308172:+		[6]
Sequence	AGGATGGAAGGGAACTCTGCACAAAACCTTTGCTTTGCTAG
Motif Score	2.830589286
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73321
mod ID: M6ASITE077008		Click to Show/Hide the Full List
mod site	chr1:203308176-203308177:+		[7]
Sequence	GGAAGGGAACTCTGCACAAAACCTTTGCTTTGCTAGTGCTG
Motif Score	2.185083333
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73322
mod ID: M6ASITE077009		Click to Show/Hide the Full List
mod site	chr1:203308308-203308309:+		[3]
Sequence	AAACTCTTCCTTTTGGAACCACATGAAAGTCTTGATGCTGC
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73323
mod ID: M6ASITE077010		Click to Show/Hide the Full List
mod site	chr1:203308363-203308364:+		[6]
Sequence	TGAGAGGTGGCTCAAAAGCTACAGGGAACTCCAGGTCCTTT
Motif Score	2.078666667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73324
mod ID: M6ASITE077011		Click to Show/Hide the Full List
mod site	chr1:203308387-203308388:+		[6]
Sequence	GGAACTCCAGGTCCTTTATTACTGCCTTCTTTTCAAAAGCA
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73325
mod ID: M6ASITE077012		Click to Show/Hide the Full List
mod site	chr1:203308407-203308408:+		[3]
Sequence	ACTGCCTTCTTTTCAAAAGCACAACTCTCCTCTAACCCTCC
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73326
mod ID: M6ASITE077013		Click to Show/Hide the Full List
mod site	chr1:203308410-203308411:+		[6]
Sequence	GCCTTCTTTTCAAAAGCACAACTCTCCTCTAACCCTCCCCT
Motif Score	2.595904762
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73327
mod ID: M6ASITE077014		Click to Show/Hide the Full List
mod site	chr1:203308477-203308478:+		[6]
Sequence	GAGCTACCGTATTTTCTAGGACAAGAGTTCTCAGTCACTGT
Motif Score	3.643047619
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73328
mod ID: M6ASITE077015		Click to Show/Hide the Full List
mod site	chr1:203308537-203308538:+		[6]
Sequence	CCAGGAGGGTCTGGAGGAAAACTGGCTATCAGAACCTCCTG
Motif Score	2.627720238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73329
mod ID: M6ASITE077016		Click to Show/Hide the Full List
mod site	chr1:203308697-203308698:+		[6]
Sequence	TTGGTATTCTTGTAGGGCCGACACTAAATAAAAGCCAAACC
Motif Score	2.865571429
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73330
mod ID: M6ASITE077017		Click to Show/Hide the Full List
mod site	chr1:203308783-203308784:+		[6]
Sequence	AGGTTGCTGTCTGTCTCAGTACAATCCAAATTTGTCGTAGA
Motif Score	2.856142857
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73331
mod ID: M6ASITE077018		Click to Show/Hide the Full List
mod site	chr1:203308849-203308850:+		[3]
Sequence	TTGGAGAAAAGTGGAAAGCTACACTGGGAAGAAACTCCCTT
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73332
mod ID: M6ASITE077019		Click to Show/Hide the Full List
mod site	chr1:203308911-203308912:+		[7]
Sequence	TGATGAGGGGTCCTCAAAAGACCTCGAGTTTCCCAAACCGA
Motif Score	2.876744048
Cell/Tissue List	MT4
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73333
mod ID: M6ASITE077020		Click to Show/Hide the Full List
mod site	chr1:203308927-203308928:+		[6]
Sequence	AAAGACCTCGAGTTTCCCAAACCGAATCACCTTAAGAAGGA
Motif Score	2.185083333
Cell/Tissue List	HEK293T; MT4
Seq Type List	DART-seq; MeRIP-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73334
mod ID: M6ASITE077021		Click to Show/Hide the Full List
mod site	chr1:203308947-203308948:+		[2]
Sequence	ACCGAATCACCTTAAGAAGGACAGGGCTAGGGCATTTGGCC
Motif Score	3.643047619
Cell/Tissue List	HeLa; MT4; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73335
mod ID: M6ASITE077022		Click to Show/Hide the Full List
mod site	chr1:203309075-203309076:+		[2]
Sequence	CCCCTTTCCTGGATTTCTAAACTGCTCAATTTTGACTCAAA
Motif Score	2.627720238
Cell/Tissue List	HeLa; MT4; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73336
mod ID: M6ASITE077023		Click to Show/Hide the Full List
mod site	chr1:203309089-203309090:+		[6]
Sequence	TTCTAAACTGCTCAATTTTGACTCAAAGGTGCTATTTACCA
Motif Score	3.28175
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73337
mod ID: M6ASITE077024		Click to Show/Hide the Full List
mod site	chr1:203309111-203309112:+		[2]
Sequence	TCAAAGGTGCTATTTACCAAACACTCTCCCTACCCATTCCT
Motif Score	2.20572619
Cell/Tissue List	HeLa; hESC-HEK293T; U2OS; Huh7
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73338
mod ID: M6ASITE077025		Click to Show/Hide the Full List
mod site	chr1:203309113-203309114:+		[6]
Sequence	AAAGGTGCTATTTACCAAACACTCTCCCTACCCATTCCTGC
Motif Score	2.506922619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73339
mod ID: M6ASITE077026		Click to Show/Hide the Full List
mod site	chr1:203309153-203309154:+		[6]
Sequence	CCAGCTCTGCCTCCTTTTCAACTCTCCACATTTTGTATTGC
Motif Score	2.595904762
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73340
mod ID: M6ASITE077027		Click to Show/Hide the Full List
mod site	chr1:203309160-203309161:+		[3]
Sequence	TGCCTCCTTTTCAACTCTCCACATTTTGTATTGCCTTCCCA
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73341
mod ID: M6ASITE077028		Click to Show/Hide the Full List
mod site	chr1:203309182-203309183:+		[8]
Sequence	ATTTTGTATTGCCTTCCCAGACCTGCTTCCAGTCTTTATTG
Motif Score	2.876744048
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73342
mod ID: M6ASITE077029		Click to Show/Hide the Full List
mod site	chr1:203309263-203309264:+		[6]
Sequence	TTTCTGGTTTGTGGGTTGAAACAAAGCTGTGAATCACTGCA
Motif Score	2.20572619
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73343
mod ID: M6ASITE077030		Click to Show/Hide the Full List
mod site	chr1:203309278-203309279:+		[6]
Sequence	TTGAAACAAAGCTGTGAATCACTGCAGGCTGTGTTCTTGCA
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73344
mod ID: M6ASITE077031		Click to Show/Hide the Full List
mod site	chr1:203309311-203309312:+		[6]
Sequence	TTCTTGCATCTTGTCTGCAAACAGGTCCCTGCCTTTTTAGA
Motif Score	2.20572619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73345
mod ID: M6ASITE077032		Click to Show/Hide the Full List
mod site	chr1:203309388-203309389:+		[6]
Sequence	TTCTCTTCTTTATGATGTTCACTTTAAAAACAACAAAACCC
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73346
mod ID: M6ASITE077033		Click to Show/Hide the Full List
mod site	chr1:203309397-203309398:+		[3]
Sequence	TTATGATGTTCACTTTAAAAACAACAAAACCCCTGAGCTGG
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73347
mod ID: M6ASITE077034		Click to Show/Hide the Full List
mod site	chr1:203309400-203309401:+		[6]
Sequence	TGATGTTCACTTTAAAAACAACAAAACCCCTGAGCTGGACT
Motif Score	2.173910714
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73348
mod ID: M6ASITE077035		Click to Show/Hide the Full List
mod site	chr1:203309488-203309489:+		[6]
Sequence	TATGTTTGTAAGCTATTCTGACAGAAAAGACAAAGGTTACT
Motif Score	2.859755952
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73349
mod ID: M6ASITE077036		Click to Show/Hide the Full List
mod site	chr1:203309497-203309498:+		[2]
Sequence	AAGCTATTCTGACAGAAAAGACAAAGGTTACTAATTGTATG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T
Seq Type List	m6A-seq; DART-seq; MAZTER-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73350
mod ID: M6ASITE077037		Click to Show/Hide the Full List
mod site	chr1:203309506-203309507:+		[6]
Sequence	TGACAGAAAAGACAAAGGTTACTAATTGTATGATAGTGTTT
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73351
mod ID: M6ASITE077038		Click to Show/Hide the Full List
mod site	chr1:203309554-203309555:+		[6]
Sequence	GAAGAATGTACAGCTTATGGACAAATGTACACCTTTTTGTT
Motif Score	3.643047619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000290551.5; ENST00000475157.1
External Link	RMBase: m6A_site_73352
mod ID: M6ASITE077039		Click to Show/Hide the Full List
mod site	chr1:203309562-203309563:+		[6]
Sequence	TACAGCTTATGGACAAATGTACACCTTTTTGTTACTTTAAT
Motif Score	2.856142857
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000475157.1; ENST00000290551.5
External Link	RMBase: m6A_site_73353
mod ID: M6ASITE077040		Click to Show/Hide the Full List
mod site	chr1:203309575-203309576:+		[6]
Sequence	CAAATGTACACCTTTTTGTTACTTTAATAAAAATGTAGTAG
Motif Score	2.494845238
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000290551.5
External Link	RMBase: m6A_site_73354

Ref 1	Gene amplification-driven RNA methyltransferase KIAA1429 promotes tumorigenesis by regulating BTG2 via m6A-YTHDF2-dependent in lung adenocarcinoma. Cancer Commun (Lond). 2022 Jul;42(7):609-626. doi: 10.1002/cac2.12325. Epub 2022 Jun 21.
Ref 2	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 3	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 4	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 5	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 6	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 7	Dynamics of the human and viral m(6)A RNA methylomes during HIV-1 infection of T cells. Nat Microbiol. 2016 Feb 22;1:16011. doi: 10.1038/nmicrobiol.2016.11.
Ref 8	N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505(7481):117-20. doi: 10.1038/nature12730. Epub 2013 Nov 27.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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