m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00746)

Target Name	Pescadillo homolog (PES1)
Gene Name	PES1
Chromosomal Location	22q12.2
Family	Pescadillo family
Function	Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. Click to Show/Hide
Gene ID	23481
Uniprot ID	PESC_HUMAN
HGNC ID	HGNC:8848
KEGG ID	hsa:23481

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

PES1 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

Methyltransferase-like 3 (METTL3) [WRITER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by METTL3*
Cell Line	HeLa cell line	Homo sapiens
Treatment: METTL3 knockdown HeLa cells Control: HeLa cells		GSE70061
Regulation		logFC: 7.23E-01 p-value: 7.36E-03
More Results	Click to View More RNA-seq Results
*Representative RIP-seq result supporting the interaction between PES1 and the regulator*
Cell Line	MDA-MB-231	Homo sapiens
Regulation	logFC: 2.38E+00	GSE60213

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	m6A methyltransferase complex METTL3/METTL14 is upregulated in CML patients and that is required for proliferation of primary CML cells and CML cell lines sensitive and resistant to the TKI imatinib. METTL3 directly regulates the level of Pescadillo homolog (PES1) protein identified as an oncogene in several tumors. These results point to METTL3 as a novel relevant oncogene in CML and as a promising therapeutic target for TKI resistant CML.
Target Regulation	Down regulation
Responsed Disease	Chronic myeloid leukaemia		ICD-11: 2B33.2	Disease Info
Pathway Response	Cell cycle			hsa04110
Cell Process	Decrease of S phase
In-vitro Model	U-937	Adult acute monocytic leukemia	Homo sapiens	CVCL_0007
	NB4	Acute promyelocytic leukemia	Homo sapiens	CVCL_0005
	LAMA-84	Chronic myelogenous leukemia	Homo sapiens	CVCL_0388
	KCL-22	Chronic myelogenous leukemia	Homo sapiens	CVCL_2091
	K-562	Chronic myelogenous leukemia	Homo sapiens	CVCL_0004
	HL-60	Adult acute myeloid leukemia	Homo sapiens	CVCL_0002
	HEL	Erythroleukemia	Homo sapiens	CVCL_0001

Methyltransferase-like 14 (METTL14) [WRITER]

Regulator Info

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	m6A methyltransferase complex METTL3/METTL14 is upregulated in CML patients and that is required for proliferation of primary CML cells and CML cell lines sensitive and resistant to the TKI imatinib. METTL3 directly regulates the level of Pescadillo homolog (PES1) protein identified as an oncogene in several tumors. These results point to METTL3 as a novel relevant oncogene in CML and as a promising therapeutic target for TKI resistant CML.
Target Regulation	Down regulation
Responsed Disease	Chronic myeloid leukaemia		ICD-11: 2B33.2	Disease Info
Pathway Response	Cell cycle			hsa04110
Cell Process	Decrease of S phase
In-vitro Model	U-937	Adult acute monocytic leukemia	Homo sapiens	CVCL_0007
	NB4	Acute promyelocytic leukemia	Homo sapiens	CVCL_0005
	LAMA-84	Chronic myelogenous leukemia	Homo sapiens	CVCL_0388
	KCL-22	Chronic myelogenous leukemia	Homo sapiens	CVCL_2091
	K-562	Chronic myelogenous leukemia	Homo sapiens	CVCL_0004
	HL-60	Adult acute myeloid leukemia	Homo sapiens	CVCL_0002
	HEL	Erythroleukemia	Homo sapiens	CVCL_0001

Malignant haematopoietic neoplasm [ICD-11: 2B33]

Disease Info

In total 2 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[1]
Response Summary	m6A methyltransferase complex METTL3/METTL14 is upregulated in CML patients and that is required for proliferation of primary CML cells and CML cell lines sensitive and resistant to the TKI imatinib. METTL3 directly regulates the level of Pescadillo homolog (PES1) protein identified as an oncogene in several tumors. These results point to METTL3 as a novel relevant oncogene in CML and as a promising therapeutic target for TKI resistant CML.
Responsed Disease	Chronic myeloid leukaemia [ICD-11: 2B33.2]
Target Regulator	Methyltransferase-like 14 (METTL14)		WRITER	Regulator Info
Target Regulation	Down regulation
Pathway Response	Cell cycle			hsa04110
Cell Process	Decrease of S phase
In-vitro Model	U-937	Adult acute monocytic leukemia	Homo sapiens	CVCL_0007
	NB4	Acute promyelocytic leukemia	Homo sapiens	CVCL_0005
	LAMA-84	Chronic myelogenous leukemia	Homo sapiens	CVCL_0388
	KCL-22	Chronic myelogenous leukemia	Homo sapiens	CVCL_2091
	K-562	Chronic myelogenous leukemia	Homo sapiens	CVCL_0004
	HL-60	Adult acute myeloid leukemia	Homo sapiens	CVCL_0002
	HEL	Erythroleukemia	Homo sapiens	CVCL_0001
Experiment 2 Reporting the m6A-centered Disease Response				[1]
Response Summary	m6A methyltransferase complex METTL3/METTL14 is upregulated in CML patients and that is required for proliferation of primary CML cells and CML cell lines sensitive and resistant to the TKI imatinib. METTL3 directly regulates the level of Pescadillo homolog (PES1) protein identified as an oncogene in several tumors. These results point to METTL3 as a novel relevant oncogene in CML and as a promising therapeutic target for TKI resistant CML.
Responsed Disease	Chronic myeloid leukaemia [ICD-11: 2B33.2]
Target Regulator	Methyltransferase-like 3 (METTL3)		WRITER	Regulator Info
Target Regulation	Down regulation
Pathway Response	Cell cycle			hsa04110
Cell Process	Decrease of S phase
In-vitro Model	U-937	Adult acute monocytic leukemia	Homo sapiens	CVCL_0007
	NB4	Acute promyelocytic leukemia	Homo sapiens	CVCL_0005
	LAMA-84	Chronic myelogenous leukemia	Homo sapiens	CVCL_0388
	KCL-22	Chronic myelogenous leukemia	Homo sapiens	CVCL_2091
	K-562	Chronic myelogenous leukemia	Homo sapiens	CVCL_0004
	HL-60	Adult acute myeloid leukemia	Homo sapiens	CVCL_0002
	HEL	Erythroleukemia	Homo sapiens	CVCL_0001

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00746)

Pescadillo homolog (PES1)

N4-acetylcytidine (ac4C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000060		Click to Show/Hide the Full List
mod site	chr22:30579345-30579346:-		[2]
Sequence	TTGTCACCCTGCCAGAGAGACAGTAGATTCCCAGGGCATTC
Cell/Tissue List	H1
Seq Type List	ac4C-seq
Transcript ID List	ENST00000441668.5; ENST00000335214.8; ENST00000405677.5; ENST00000354694.12; ENST00000402281.5; ENST00000488719.1; ENST00000402284.7
External Link	RMBase: ac4C_site_1283

5-methylcytidine (m5C)

In total 5 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002898		Click to Show/Hide the Full List
mod site	chr22:30576958-30576959:-		[3]
Sequence	AGGACCTAAGTGTGATGGACCAGAGTCACTTCTCCTCCTCC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000354694.12; ENST00000441668.5; ENST00000488719.1; ENST00000402281.5; ENST00000402284.7; ENST00000405677.5; ENST00000335214.8
External Link	RMBase: m5C_site_30637
mod ID: M5CSITE002899		Click to Show/Hide the Full List
mod site	chr22:30579880-30579881:-		[3]
Sequence	GTGAACGCCAGGCTCCTTCTCCCCGTGGCAGAGTACTTCTC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000405677.5; ENST00000335214.8; ENST00000354694.12; ENST00000402281.5; ENST00000402284.7; ENST00000488719.1; ENST00000441668.5
External Link	RMBase: m5C_site_30638
mod ID: M5CSITE002900		Click to Show/Hide the Full List
mod site	chr22:30584671-30584672:-		[3]
Sequence	CGGGACCTGGACGATGCCCTCTCCATGTGCTTCCTGTTTTC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000406208.7; ENST00000354694.12; ENST00000335214.8; ENST00000405677.5; ENST00000402284.7; ENST00000477762.5; ENST00000402281.5
External Link	RMBase: m5C_site_30639
mod ID: M5CSITE002901		Click to Show/Hide the Full List
mod site	chr22:30584685-30584686:-		[3]
Sequence	TCATCGATGCCCTGCGGGACCTGGACGATGCCCTCTCCATG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000477762.5; ENST00000402284.7; ENST00000354694.12; ENST00000406208.7; ENST00000335214.8; ENST00000405677.5; ENST00000402281.5
External Link	RMBase: m5C_site_30640
mod ID: M5CSITE002902		Click to Show/Hide the Full List
mod site	chr22:30588058-30588059:-		[3]
Sequence	TCAAAGACATCAGGTTTCTCCTCCACGAACCCATTGTCAAC
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000354694.12; ENST00000433575.5; ENST00000335214.8; ENST00000402284.7; ENST00000405677.5; ENST00000406208.7; ENST00000466614.1; ENST00000402281.5
External Link	RMBase: m5C_site_30641

N6-methyladenosine (m6A)

In total 59 m6A sequence/site(s) in this target gene
mod ID: M6ASITE057450		Click to Show/Hide the Full List
mod site	chr22:30576641-30576642:-		[4]
Sequence	ATTTGTTATTAAATGACTGGACTTTTGTGCCAATTGCATTT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; CD8T; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; MSC; TIME; TREX; iSLK; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000488719.1; ENST00000405677.5; ENST00000402281.5; ENST00000441668.5; ENST00000354694.12
External Link	RMBase: m6A_site_561531
mod ID: M6ASITE057451		Click to Show/Hide the Full List
mod site	chr22:30576707-30576708:-		[4]
Sequence	GCCCCCTCCCACACAGTTGGACCCGTGATTCTCAGGGTGCT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; MSC; TIME; TREX; iSLK; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000488719.1; ENST00000402281.5; ENST00000405677.5; ENST00000441668.5; ENST00000402284.7; ENST00000354694.12
External Link	RMBase: m6A_site_561532
mod ID: M6ASITE057452		Click to Show/Hide the Full List
mod site	chr22:30576756-30576757:-		[5]
Sequence	GCCCACCCAGCCCCCTACCTACTGCCCCCATTCATCCTGGC
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000441668.5; ENST00000354694.12; ENST00000402281.5; ENST00000488719.1; ENST00000405677.5; ENST00000402284.7
External Link	RMBase: m6A_site_561533
mod ID: M6ASITE057453		Click to Show/Hide the Full List
mod site	chr22:30576960-30576961:-		[4]
Sequence	AGAGGACCTAAGTGTGATGGACCAGAGTCACTTCTCCTCCT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; MSC; TIME; TREX; iSLK; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000354694.12; ENST00000335214.8; ENST00000488719.1; ENST00000402284.7; ENST00000402281.5; ENST00000405677.5; ENST00000441668.5
External Link	RMBase: m6A_site_561534
mod ID: M6ASITE057454		Click to Show/Hide the Full List
mod site	chr22:30576975-30576976:-		[4]
Sequence	TGGCAGAGGCAGGCCAGAGGACCTAAGTGTGATGGACCAGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; MSC; TIME; TREX; iSLK; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000354694.12; ENST00000405677.5; ENST00000335214.8; ENST00000402284.7; ENST00000488719.1; ENST00000441668.5; ENST00000402281.5
External Link	RMBase: m6A_site_561535
mod ID: M6ASITE057455		Click to Show/Hide the Full List
mod site	chr22:30577124-30577125:-		[6]
Sequence	GCCTTCCCCCTCACAGGCCAACAAGCTGGCGGAGAAGCGGA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000441668.5; ENST00000335214.8; ENST00000402281.5; ENST00000488719.1; ENST00000405677.5; ENST00000402284.7; ENST00000354694.12
External Link	RMBase: m6A_site_561536
mod ID: M6ASITE057456		Click to Show/Hide the Full List
mod site	chr22:30579032-30579033:-		[4]
Sequence	GGACTGTGGAGGTCGGGAGAACCTGCCCCCATAAGCACCCT
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; MSC; TIME; TREX; iSLK; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000441668.5; ENST00000488719.1; ENST00000402284.7; ENST00000405677.5; ENST00000354694.12; ENST00000402281.5; ENST00000335214.8
External Link	RMBase: m6A_site_561537
mod ID: M6ASITE057457		Click to Show/Hide the Full List
mod site	chr22:30579050-30579051:-		[4]
Sequence	AGAAGGTCAGGAGCCAGAGGACTGTGGAGGTCGGGAGAACC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; A549; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; MSC; iSLK; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000441668.5; ENST00000335214.8; ENST00000402284.7; ENST00000354694.12; ENST00000402281.5; ENST00000405677.5; ENST00000488719.1
External Link	RMBase: m6A_site_561538
mod ID: M6ASITE057458		Click to Show/Hide the Full List
mod site	chr22:30579260-30579261:-		[6]
Sequence	GGAGGAGGAAGAGGACGACAACAACGAAGGTGATGGTGATG
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000354694.12; ENST00000402284.7; ENST00000402281.5; ENST00000335214.8; ENST00000405677.5; ENST00000441668.5; ENST00000488719.1
External Link	RMBase: m6A_site_561539
mod ID: M6ASITE057459		Click to Show/Hide the Full List
mod site	chr22:30579263-30579264:-		[6]
Sequence	AGAGGAGGAGGAAGAGGACGACAACAACGAAGGTGATGGTG
Motif Score	2.865571429
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000488719.1; ENST00000354694.12; ENST00000402284.7; ENST00000405677.5; ENST00000402281.5; ENST00000335214.8; ENST00000441668.5
External Link	RMBase: m6A_site_561540
mod ID: M6ASITE057460		Click to Show/Hide the Full List
mod site	chr22:30579299-30579300:-		[4]
Sequence	ACATTGGCTTTCTCTAGGAAACCTGAATGAGTCAGAAGAGG
Motif Score	2.185083333
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; A549; LCLs; MT4; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; MSC; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000354694.12; ENST00000402281.5; ENST00000488719.1; ENST00000405677.5; ENST00000402284.7; ENST00000335214.8; ENST00000441668.5
External Link	RMBase: m6A_site_561541
mod ID: M6ASITE057461		Click to Show/Hide the Full List
mod site	chr22:30579319-30579320:-		[4]
Sequence	ATTCCCAGGGCATTCAGAGGACATTGGCTTTCTCTAGGAAA
Motif Score	3.643047619
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; A549; LCLs; MT4; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000488719.1; ENST00000441668.5; ENST00000354694.12; ENST00000402284.7; ENST00000335214.8; ENST00000402281.5; ENST00000405677.5
External Link	RMBase: m6A_site_561542
mod ID: M6ASITE057462		Click to Show/Hide the Full List
mod site	chr22:30579346-30579347:-		[4]
Sequence	GTTGTCACCCTGCCAGAGAGACAGTAGATTCCCAGGGCATT
Motif Score	2.897386905
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; A549; LCLs; MT4; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000405677.5; ENST00000335214.8; ENST00000402284.7; ENST00000488719.1; ENST00000402281.5; ENST00000354694.12; ENST00000441668.5
External Link	RMBase: m6A_site_561543
mod ID: M6ASITE057463		Click to Show/Hide the Full List
mod site	chr22:30579416-30579417:-		[4]
Sequence	CACAATTGGGACATCCCTGAACTGCCCATGGCTAAAGACGG
Motif Score	3.373380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000405677.5; ENST00000402284.7; ENST00000402281.5; ENST00000441668.5; ENST00000354694.12; ENST00000488719.1; ENST00000335214.8
External Link	RMBase: m6A_site_561544
mod ID: M6ASITE057464		Click to Show/Hide the Full List
mod site	chr22:30579426-30579427:-		[4]
Sequence	AAGAGAGGGCCACAATTGGGACATCCCTGAACTGCCCATGG
Motif Score	3.643047619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000402284.7; ENST00000441668.5; ENST00000335214.8; ENST00000488719.1; ENST00000354694.12; ENST00000405677.5; ENST00000402281.5
External Link	RMBase: m6A_site_561545
mod ID: M6ASITE057465		Click to Show/Hide the Full List
mod site	chr22:30579735-30579736:-		[4]
Sequence	ACCCAGGTGAGCGGGATGGGACTGGGCTGGCCTTGACCCCT
Motif Score	4.065041667
Cell/Tissue List	HeLa; peripheral-blood; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000488719.1; ENST00000335214.8; ENST00000402281.5; ENST00000402284.7; ENST00000441668.5; ENST00000405677.5; ENST00000354694.12
External Link	RMBase: m6A_site_561546
mod ID: M6ASITE057466		Click to Show/Hide the Full List
mod site	chr22:30579755-30579756:-		[4]
Sequence	GGCTCTGCAGCGGGGAGAGGACCCAGGTGAGCGGGATGGGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; peripheral-blood; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000402284.7; ENST00000405677.5; ENST00000488719.1; ENST00000441668.5; ENST00000354694.12; ENST00000335214.8; ENST00000402281.5
External Link	RMBase: m6A_site_561547
mod ID: M6ASITE057467		Click to Show/Hide the Full List
mod site	chr22:30579841-30579842:-		[6]
Sequence	TCTGGGGTGCAGCTGCCCCCACACCTTTCACCCTTTGTGAC
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000402284.7; ENST00000335214.8; ENST00000402281.5; ENST00000405677.5; ENST00000488719.1; ENST00000354694.12; ENST00000441668.5
External Link	RMBase: m6A_site_561548
mod ID: M6ASITE057468		Click to Show/Hide the Full List
mod site	chr22:30579983-30579984:-		[4]
Sequence	AGGCCCTGCGATGCAGCAGGACCCTGAGTTGCCCTCTGTGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; peripheral-blood; endometrial; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000354694.12; ENST00000335214.8; ENST00000488719.1; ENST00000402281.5; ENST00000402284.7; ENST00000405677.5
External Link	RMBase: m6A_site_561549
mod ID: M6ASITE057469		Click to Show/Hide the Full List
mod site	chr22:30580068-30580069:-		[4]
Sequence	TCGACCGGCCTGGGCAGCAGACCTCAGTCATTGGCAGGTAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; Huh7; peripheral-blood; endometrial; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000402281.5; ENST00000402284.7; ENST00000405677.5; ENST00000335214.8; ENST00000354694.12; ENST00000488719.1
External Link	RMBase: m6A_site_561550
mod ID: M6ASITE057470		Click to Show/Hide the Full List
mod site	chr22:30580112-30580113:-		[4]
Sequence	GGCCACCTATGACGTCACAGACTCCCGCATCACCCATCAGA
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; Huh7; peripheral-blood; HEK293T; endometrial; NB4; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000335214.8; ENST00000402284.7; ENST00000405677.5; ENST00000402281.5; ENST00000354694.12
External Link	RMBase: m6A_site_561551
mod ID: M6ASITE057471		Click to Show/Hide the Full List
mod site	chr22:30580116-30580117:-		[7]
Sequence	TTGGGGCCACCTATGACGTCACAGACTCCCGCATCACCCAT
Motif Score	2.047297619
Cell/Tissue List	HEK293
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000402284.7; ENST00000402281.5; ENST00000354694.12; ENST00000405677.5; ENST00000335214.8
External Link	RMBase: m6A_site_561552
mod ID: M6ASITE057472		Click to Show/Hide the Full List
mod site	chr22:30580151-30580152:-		[4]
Sequence	TGGTGGGGAAGTGTCCTGGGACAAATCTTTGTGCATTGGGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; hESC-HEK293T; Huh7; CD4T; peripheral-blood; endometrial; HEC-1-A; NB4; MM6
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000402281.5; ENST00000402284.7; ENST00000354694.12; ENST00000335214.8; ENST00000405677.5
External Link	RMBase: m6A_site_561553
mod ID: M6ASITE057473		Click to Show/Hide the Full List
mod site	chr22:30580609-30580610:-		[4]
Sequence	GGGCCTGAAGTTCTTCCTGAACCGAGAGGTGCCCCGTGAGG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; MM6; Huh7; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000402281.5; ENST00000405677.5; ENST00000335214.8; ENST00000402284.7; ENST00000354694.12
External Link	RMBase: m6A_site_561554
mod ID: M6ASITE057474		Click to Show/Hide the Full List
mod site	chr22:30580645-30580646:-		[6]
Sequence	GCTGGAGGCGCAGGAGAAGCACAAGAAGCTTTTTGAGGGCC
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000354694.12; ENST00000402281.5; ENST00000335214.8; ENST00000405677.5; ENST00000402284.7
External Link	RMBase: m6A_site_561555
mod ID: M6ASITE057475		Click to Show/Hide the Full List
mod site	chr22:30580678-30580679:-		[4]
Sequence	GATGTCAGCGCAGGAGGAAGACCGCAGGAAGGAGCTGGAGG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; MM6; CD4T; peripheral-blood; GSC-11; HEK293T; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000405677.5; ENST00000402281.5; ENST00000402284.7; ENST00000354694.12; ENST00000335214.8
External Link	RMBase: m6A_site_561556
mod ID: M6ASITE057476		Click to Show/Hide the Full List
mod site	chr22:30581098-30581099:-		[4]
Sequence	CCCCCTTCTCTCCTGTAGAAACTGGCAGCCCTCAGTGCCAG
Motif Score	2.627720238
Cell/Tissue List	HeLa; CD34; HepG2; MM6; peripheral-blood; GSC-11; HEK293T; endometrial; NB4
Seq Type List	m6A-seq
Transcript ID List	ENST00000402284.7; ENST00000335214.8; ENST00000405677.5; ENST00000402281.5; ENST00000354694.12
External Link	RMBase: m6A_site_561557
mod ID: M6ASITE057477		Click to Show/Hide the Full List
mod site	chr22:30581352-30581353:-		[4]
Sequence	TGAGGGCACCTACGCGTTGGACTCCGAGAGTTGTATGGAGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; CD34; HepG2; peripheral-blood; HEK293T; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000354694.12; ENST00000406208.7; ENST00000405677.5; ENST00000402284.7; ENST00000402281.5; ENST00000335214.8
External Link	RMBase: m6A_site_561558
mod ID: M6ASITE057478		Click to Show/Hide the Full List
mod site	chr22:30581627-30581628:-		[4]
Sequence	CCAGCACCCGACAGACGTGGACTACAGGGTCATGGCCACCT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; Huh7; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000354694.12; ENST00000405677.5; ENST00000406208.7; ENST00000402281.5; ENST00000335214.8; ENST00000402284.7
External Link	RMBase: m6A_site_561559
mod ID: M6ASITE057479		Click to Show/Hide the Full List
mod site	chr22:30581637-30581638:-		[7]
Sequence	CTTGTGTTCCCCAGCACCCGACAGACGTGGACTACAGGGTC
Motif Score	2.865571429
Cell/Tissue List	brain
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000402281.5; ENST00000354694.12; ENST00000406208.7; ENST00000335214.8; ENST00000405677.5; ENST00000402284.7
External Link	RMBase: m6A_site_561560
mod ID: M6ASITE057480		Click to Show/Hide the Full List
mod site	chr22:30584318-30584319:-		[8]
Sequence	GGGCTTGTGCTGCCTCCTAGACAGATATGGATGTGGAGGAA
Motif Score	2.897386905
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000406208.7; ENST00000402281.5; ENST00000402284.7; ENST00000335214.8; ENST00000477762.5; ENST00000354694.12; ENST00000405677.5
External Link	RMBase: m6A_site_561561
mod ID: M6ASITE057481		Click to Show/Hide the Full List
mod site	chr22:30584573-30584574:-		[6]
Sequence	CACTGTGGAGTTCATGCACTACATTATCGCTGCCCGTGCCC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000405677.5; ENST00000406208.7; ENST00000402281.5; ENST00000335214.8; ENST00000354694.12; ENST00000477762.5; ENST00000402284.7
External Link	RMBase: m6A_site_561562
mod ID: M6ASITE057482		Click to Show/Hide the Full List
mod site	chr22:30584616-30584617:-		[4]
Sequence	CTGGCAAGTGCCACGTGCAGACCATTCAGCTGTGCCGCCGG
Motif Score	2.876744048
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000477762.5; ENST00000406208.7; ENST00000402284.7; ENST00000354694.12; ENST00000335214.8; ENST00000402281.5; ENST00000405677.5
External Link	RMBase: m6A_site_561563
mod ID: M6ASITE057483		Click to Show/Hide the Full List
mod site	chr22:30584637-30584638:-		[4]
Sequence	TGTTTTCCACCTTCCCGCGGACTGGCAAGTGCCACGTGCAG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000402281.5; ENST00000402284.7; ENST00000335214.8; ENST00000477762.5; ENST00000405677.5; ENST00000406208.7; ENST00000354694.12
External Link	RMBase: m6A_site_561564
mod ID: M6ASITE057484		Click to Show/Hide the Full List
mod site	chr22:30584687-30584688:-		[4]
Sequence	GTTCATCGATGCCCTGCGGGACCTGGACGATGCCCTCTCCA
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000477762.5; ENST00000335214.8; ENST00000405677.5; ENST00000402281.5; ENST00000354694.12; ENST00000406208.7; ENST00000402284.7
External Link	RMBase: m6A_site_561565
mod ID: M6ASITE057485		Click to Show/Hide the Full List
mod site	chr22:30585238-30585239:-		[4]
Sequence	TCATTGGTTCTGCCAACTAGACATGTCCAAGGGATGAGAGG
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000402281.5; ENST00000335214.8; ENST00000433575.5; ENST00000477762.5; ENST00000354694.12; ENST00000406208.7; ENST00000405677.5; ENST00000402284.7
External Link	RMBase: m6A_site_561566
mod ID: M6ASITE057486		Click to Show/Hide the Full List
mod site	chr22:30585275-30585276:-		[4]
Sequence	TCTGCTCTGGCTCTTCCTGGACCCAATTCCCTGGGTCTCAT
Motif Score	3.622404762
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000433575.5; ENST00000406208.7; ENST00000335214.8; ENST00000402281.5; ENST00000477762.5; ENST00000354694.12; ENST00000402284.7; ENST00000405677.5
External Link	RMBase: m6A_site_561567
mod ID: M6ASITE057487		Click to Show/Hide the Full List
mod site	chr22:30585301-30585302:-		[4]
Sequence	TTACCAGAGGATTCCCCGAAACACATTCTGCTCTGGCTCTT
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000354694.12; ENST00000402281.5; ENST00000402284.7; ENST00000405677.5; ENST00000335214.8; ENST00000477762.5; ENST00000406208.7; ENST00000433575.5
External Link	RMBase: m6A_site_561568
mod ID: M6ASITE057488		Click to Show/Hide the Full List
mod site	chr22:30587146-30587147:-		[8]
Sequence	TTCAAGGACACAGACCAAAAACCAAGCTAGCAAATTACTAT
Motif Score	2.185083333
Cell/Tissue List	Huh7; HEK293A-TOA; TIME
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000433575.5; ENST00000335214.8; ENST00000402284.7; ENST00000354694.12; ENST00000466614.1; ENST00000477762.5; ENST00000402281.5; ENST00000406208.7; ENST00000405677.5
External Link	RMBase: m6A_site_561569
mod ID: M6ASITE057489		Click to Show/Hide the Full List
mod site	chr22:30587153-30587154:-		[8]
Sequence	CAACTTTTTCAAGGACACAGACCAAAAACCAAGCTAGCAAA
Motif Score	2.876744048
Cell/Tissue List	Huh7; HEK293A-TOA; TIME
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000335214.8; ENST00000433575.5; ENST00000477762.5; ENST00000406208.7; ENST00000402284.7; ENST00000405677.5; ENST00000466614.1; ENST00000354694.12; ENST00000402281.5
External Link	RMBase: m6A_site_561570
mod ID: M6ASITE057490		Click to Show/Hide the Full List
mod site	chr22:30587159-30587160:-		[8]
Sequence	AGCTTGCAACTTTTTCAAGGACACAGACCAAAAACCAAGCT
Motif Score	3.643047619
Cell/Tissue List	HEK293T; Huh7; HEK293A-TOA; TIME
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000405677.5; ENST00000402284.7; ENST00000335214.8; ENST00000354694.12; ENST00000433575.5; ENST00000406208.7; ENST00000402281.5; ENST00000477762.5; ENST00000466614.1
External Link	RMBase: m6A_site_561571
mod ID: M6ASITE057491		Click to Show/Hide the Full List
mod site	chr22:30587171-30587172:-		[9]
Sequence	CCCTGCTCAAAGAGCTTGCAACTTTTTCAAGGACACAGACC
Motif Score	2.595904762
Cell/Tissue List	CD8T
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000405677.5; ENST00000354694.12; ENST00000433575.5; ENST00000402281.5; ENST00000335214.8; ENST00000466614.1; ENST00000406208.7; ENST00000477762.5; ENST00000402284.7
External Link	RMBase: m6A_site_561572
mod ID: M6ASITE057492		Click to Show/Hide the Full List
mod site	chr22:30587192-30587193:-		[4]
Sequence	CAATAGGGAATAAGACCAAGACCCTGCTCAAAGAGCTTGCA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000406208.7; ENST00000477762.5; ENST00000402281.5; ENST00000405677.5; ENST00000402284.7; ENST00000354694.12; ENST00000335214.8; ENST00000433575.5; ENST00000466614.1
External Link	RMBase: m6A_site_561573
mod ID: M6ASITE057493		Click to Show/Hide the Full List
mod site	chr22:30587198-30587199:-		[4]
Sequence	GGGATACAATAGGGAATAAGACCAAGACCCTGCTCAAAGAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000466614.1; ENST00000477762.5; ENST00000433575.5; ENST00000402281.5; ENST00000405677.5; ENST00000402284.7; ENST00000335214.8; ENST00000354694.12; ENST00000406208.7
External Link	RMBase: m6A_site_561574
mod ID: M6ASITE057494		Click to Show/Hide the Full List
mod site	chr22:30587263-30587264:-		[4]
Sequence	TGAGCCGGGCTTTCCTCAGGACACTGCTGTTTCTTCATTTA
Motif Score	3.643047619
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000335214.8; ENST00000405677.5; ENST00000402281.5; ENST00000477762.5; ENST00000406208.7; ENST00000354694.12; ENST00000466614.1; ENST00000433575.5; ENST00000402284.7
External Link	RMBase: m6A_site_561575
mod ID: M6ASITE057495		Click to Show/Hide the Full List
mod site	chr22:30587300-30587301:-		[6]
Sequence	GCCCAACTACAAACTCGACCACATCATCAAGGAACGGTGAG
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000405677.5; ENST00000402284.7; ENST00000402281.5; ENST00000477762.5; ENST00000406208.7; ENST00000335214.8; ENST00000433575.5; ENST00000466614.1; ENST00000354694.12
External Link	RMBase: m6A_site_561576
mod ID: M6ASITE057496		Click to Show/Hide the Full List
mod site	chr22:30587308-30587309:-		[4]
Sequence	GACAATAAGCCCAACTACAAACTCGACCACATCATCAAGGA
Motif Score	2.627720238
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000477762.5; ENST00000406208.7; ENST00000402281.5; ENST00000466614.1; ENST00000354694.12; ENST00000402284.7; ENST00000405677.5; ENST00000433575.5; ENST00000335214.8
External Link	RMBase: m6A_site_561577
mod ID: M6ASITE057497		Click to Show/Hide the Full List
mod site	chr22:30587327-30587328:-		[4]
Sequence	CACTGTAGAGCGTTTAAAGGACAATAAGCCCAACTACAAAC
Motif Score	3.643047619
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000402281.5; ENST00000405677.5; ENST00000477762.5; ENST00000433575.5; ENST00000354694.12; ENST00000402284.7; ENST00000335214.8; ENST00000406208.7; ENST00000466614.1
External Link	RMBase: m6A_site_561578
mod ID: M6ASITE057498		Click to Show/Hide the Full List
mod site	chr22:30587348-30587349:-		[4]
Sequence	TTATGGGAAGAGCGAGTGGAACACTGTAGAGCGTTTAAAGG
Motif Score	2.951386905
Cell/Tissue List	HeLa; hESC-HEK293T; Huh7
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000354694.12; ENST00000402284.7; ENST00000477762.5; ENST00000405677.5; ENST00000466614.1; ENST00000433575.5; ENST00000335214.8; ENST00000406208.7; ENST00000402281.5
External Link	RMBase: m6A_site_561579
mod ID: M6ASITE057499		Click to Show/Hide the Full List
mod site	chr22:30588024-30588025:-		[6]
Sequence	TGTCAACAAGTTCCGTGAATACAAGGTGAGGTCTGGGCTCT
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000405677.5; ENST00000354694.12; ENST00000406208.7; ENST00000402284.7; ENST00000433575.5; ENST00000335214.8; ENST00000402281.5; ENST00000466614.1
External Link	RMBase: m6A_site_561580
mod ID: M6ASITE057500		Click to Show/Hide the Full List
mod site	chr22:30588050-30588051:-		[4]
Sequence	ATCAGGTTTCTCCTCCACGAACCCATTGTCAACAAGTTCCG
Motif Score	2.930744048
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000335214.8; ENST00000354694.12; ENST00000402281.5; ENST00000406208.7; ENST00000405677.5; ENST00000466614.1; ENST00000433575.5; ENST00000402284.7
External Link	RMBase: m6A_site_561581
mod ID: M6ASITE057501		Click to Show/Hide the Full List
mod site	chr22:30588072-30588073:-		[4]
Sequence	AACGTTTTACCTTATCAAAGACATCAGGTTTCTCCTCCACG
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000402281.5; ENST00000405677.5; ENST00000466614.1; ENST00000402284.7; ENST00000335214.8; ENST00000433575.5; ENST00000406208.7; ENST00000354694.12
External Link	RMBase: m6A_site_561582
mod ID: M6ASITE057502		Click to Show/Hide the Full List
mod site	chr22:30588131-30588132:-		[4]
Sequence	ATTTATCCCCATGAACCCAAACACAAGAAGAAGGTTAACAA
Motif Score	2.20572619
Cell/Tissue List	HeLa; A549; hESC-HEK293T
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000406208.7; ENST00000402281.5; ENST00000405677.5; ENST00000466614.1; ENST00000433575.5; ENST00000335214.8; ENST00000354694.12; ENST00000402284.7
External Link	RMBase: m6A_site_561583
mod ID: M6ASITE057503		Click to Show/Hide the Full List
mod site	chr22:30588137-30588138:-		[4]
Sequence	AAGGGCATTTATCCCCATGAACCCAAACACAAGAAGAAGGT
Motif Score	2.930744048
Cell/Tissue List	HeLa; A549
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000354694.12; ENST00000433575.5; ENST00000466614.1; ENST00000335214.8; ENST00000406208.7; ENST00000402284.7; ENST00000405677.5; ENST00000402281.5
External Link	RMBase: m6A_site_561584
mod ID: M6ASITE057504		Click to Show/Hide the Full List
mod site	chr22:30589232-30589233:-		[4]
Sequence	CACCAACTACATCACCCGGAACAAAGCCCGGAAGAAGCTCC
Motif Score	2.951386905
Cell/Tissue List	HeLa; A549; hESC-HEK293T; MT4; Huh7; HEK293A-TOA; MSC; TIME; TREX; iSLK
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000405677.5; ENST00000335214.8; ENST00000402284.7; ENST00000354694.12; ENST00000466614.1; ENST00000406208.7; ENST00000402281.5; ENST00000433575.5
External Link	RMBase: m6A_site_561585
mod ID: M6ASITE057505		Click to Show/Hide the Full List
mod site	chr22:30589244-30589245:-		[6]
Sequence	ACGAGGCTCGGCCACCAACTACATCACCCGGAACAAAGCCC
Motif Score	2.078666667
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000433575.5; ENST00000335214.8; ENST00000406208.7; ENST00000466614.1; ENST00000405677.5; ENST00000402284.7; ENST00000354694.12; ENST00000402281.5
External Link	RMBase: m6A_site_561586
mod ID: M6ASITE057506		Click to Show/Hide the Full List
mod site	chr22:30606845-30606846:-		[10]
Sequence	TAGTGCCCACCTAGCCCAGGACAAGGAGTGGAACGGGAGCT
Motif Score	3.643047619
Cell/Tissue List	endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000402281.5; ENST00000492986.1; ENST00000467368.1; ENST00000405677.5
External Link	RMBase: m6A_site_561587
mod ID: M6ASITE057507		Click to Show/Hide the Full List
mod site	chr22:30606907-30606908:-		[11]
Sequence	TCCAGTGGTGGATTGGCAGGACCGGGTGCCTACCCGGTACT
Motif Score	3.622404762
Cell/Tissue List	H1A; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000492986.1; ENST00000402281.5; ENST00000405677.5
External Link	RMBase: m6A_site_561588
mod ID: M6ASITE057508		Click to Show/Hide the Full List
mod site	chr22:30607000-30607001:-		[12]
Sequence	TCCTGCTTAAAGAGCCCGGGACCAGCGCAGAGGGCCTGATG
Motif Score	3.622404762
Cell/Tissue List	TIME; endometrial
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000492986.1; ENST00000402281.5
External Link	RMBase: m6A_site_561593

Ref 1	New insight into the catalytic -dependent and -independent roles of METTL3 in sustaining aberrant translation in chronic myeloid leukemia. Cell Death Dis. 2021 Sep 24;12(10):870. doi: 10.1038/s41419-021-04169-7.
Ref 2	NAT10-mediated N4-acetylcytidine mRNA modification regulates self-renewal in human embryonic stem cells. Nucleic Acids Res. 2023 Sep 8;51(16):8514-8531. doi: 10.1093/nar/gkad628.
Ref 3	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 4	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 5	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 6	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 7	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 8	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 9	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 10	m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27.
Ref 11	m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell. 2014 Dec 4;15(6):707-19. doi: 10.1016/j.stem.2014.09.019. Epub 2014 Oct 16.
Ref 12	Viral and cellular N(6)-methyladenosine and N(6),2'-O-dimethyladenosine epitranscriptomes in the KSHV life cycle. Nat Microbiol. 2018 Jan;3(1):108-120. doi: 10.1038/s41564-017-0056-8. Epub 2017 Nov 6.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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