m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00696)

Target Name	Cadherin-1 (CDH1)
Synonyms	CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD324 Click to Show/Hide
Gene Name	CDH1
Chromosomal Location	16q22.1
Function	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7; E-Cad/CTF2 promotes non-amyloidogenic degradation of Abeta precursors. Has a strong inhibitory effect on APP C99 and C83 production; (Microbial infection) Serves as a receptor for Listeria monocytogenes; internalin A (InlA) binds to this protein and promotes uptake of the bacteria. Click to Show/Hide
Gene ID	999
Uniprot ID	CADH1_HUMAN
HGNC ID	HGNC:1748
KEGG ID	hsa:999

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

CDH1 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

Methyltransferase-like 3 (METTL3) [WRITER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by METTL3*
Cell Line	Caco-2 cell line	Homo sapiens
Treatment: shMETTL3 Caco-2 cells Control: shNTC Caco-2 cells		GSE167075
Regulation		logFC: -7.84E-01 p-value: 1.59E-117
More Results	Click to View More RNA-seq Results
*Representative RIP-seq result supporting the interaction between CDH1 and the regulator*
Cell Line	MDA-MB-231	Homo sapiens
Regulation	logFC: 4.00E+00	GSE60213

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene			[1]
Response Summary	PM2.5 exposure increased the levels of METTL3-mediated m6A modification of Cadherin-1 (CDH1) mRNA. PM2.5 exposure triggered EMT progression to promote the pulmonary fibrosis via miR-494-3p/YTHDF2 recognized and METTL3 mediated m6A modification.
Responsed Disease	Pulmonary Fibrosis	ICD-11: CB03.4	Disease Info
Pathway Response	Adherens junction		hsa04520
Cell Process	Epithelial-mesenchymal transition

Idiopathic interstitial pneumonitis [ICD-11: CB03]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response			[1]
Response Summary	PM2.5 exposure increased the levels of METTL3-mediated m6A modification of Cadherin-1 (CDH1) mRNA. PM2.5 exposure triggered EMT progression to promote the pulmonary fibrosis via miR-494-3p/YTHDF2 recognized and METTL3 mediated m6A modification.
Responsed Disease	Pulmonary Fibrosis [ICD-11: CB03.4]
Target Regulator	Methyltransferase-like 3 (METTL3)	WRITER	Regulator Info
Pathway Response	Adherens junction		hsa04520
Cell Process	Epithelial-mesenchymal transition

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Histone modification

m6A Regulator: Methyltransferase-like 3 (METTL3)

Regulator Info

In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03633		Crosstalk Info
Epigenetic Regulator	Histone acetyltransferase p300 (P300)
Regulated Target	Histone H3 lysine 9 lactylation (H3K9la)
Crosstalk relationship	Histone modification → m6A
Disease	Pulmonary fibrosis	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00696)

Cadherin-1 (CDH1)

Adenosine-to-Inosine editing (A-to-I)

In total 2 m6A sequence/site(s) in this target gene
mod ID: A2ISITE007424		Click to Show/Hide the Full List
mod site	chr16:68746237-68746238:+		[10]
Sequence	GTTTGAGACTAGCTTGACCAACGTGGTGAAACCCCATCTCT
Transcript ID List	ENST00000566612.5; ENST00000611625.4; ENST00000612417.4; ENST00000566510.5; ENST00000422392.6; ENST00000621016.4; rmsk_4566085; ENST00000261769.10
External Link	RMBase: RNA-editing_site_52009
mod ID: A2ISITE007425		Click to Show/Hide the Full List
mod site	chr16:68781618-68781619:+		[11]
Sequence	AAAGTGCGGGGATAACAGGCATGCAACACCATGCCCGGCCA
Transcript ID List	ENST00000612417.4; ENST00000621016.4; ENST00000261769.10; ENST00000562836.5; ENST00000566510.5; ENST00000422392.6; ENST00000564676.5; ENST00000566612.5; ENST00000611625.4; ENST00000564745.1
External Link	RMBase: RNA-editing_site_52010

5-methylcytidine (m5C)

In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE000753		Click to Show/Hide the Full List
mod site	chr16:68742543-68742544:+		[12]
Sequence	GAAGCTAAGCAGGGTCGGGCCTGGTTAGTACTAGTACTTGG
Transcript ID List	ENST00000566612.5; ENST00000261769.10; rmsk_4566072; ENST00000422392.6; ENST00000612417.4; ENST00000621016.4; ENST00000566510.5; ENST00000611625.4; ENST00000363688.1
External Link	RMBase: m5C_site_16434

N6-methyladenosine (m6A)

In total 66 m6A sequence/site(s) in this target gene
mod ID: M6ASITE027979		Click to Show/Hide the Full List
mod site	chr16:68737303-68737304:+		[13]
Sequence	CCCCTCTCAGTGGCGTCGGAACTGCAAAGCACCTGTGAGCT
Motif Score	3.373380952
Cell/Tissue List	H1A; H1B; A549; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000261769.10; ENST00000612417.4; ENST00000611625.4
External Link	RMBase: m6A_site_327639
mod ID: M6ASITE027981		Click to Show/Hide the Full List
mod site	chr16:68737341-68737342:+		[13]
Sequence	GCTTGCGGAAGTCAGTTCAGACTCCAGCCCGCTCCAGCCCG
Motif Score	3.319380952
Cell/Tissue List	H1A; H1B; A549; endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000611625.4; ENST00000612417.4; ENST00000566612.5; ENST00000261769.10; ENST00000621016.4
External Link	RMBase: m6A_site_327640
mod ID: M6ASITE027982		Click to Show/Hide the Full List
mod site	chr16:68742571-68742572:+		[14]
Sequence	TACTAGTACTTGGATGGGAGACAGGGTTTCACCATGTTGGT
Motif Score	2.897386905
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000566510.5; ENST00000566612.5; rmsk_4566072; ENST00000612417.4; ENST00000621016.4; ENST00000261769.10; ENST00000611625.4; ENST00000422392.6; ENST00000363688.1
External Link	RMBase: m6A_site_327641
mod ID: M6ASITE027983		Click to Show/Hide the Full List
mod site	chr16:68763295-68763296:+		[15]
Sequence	AGACAGAAGGGGAGAAACAAACACAGCCTGCCAATCCTGGA
Motif Score	2.20572619
Cell/Tissue List	endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000612417.4; ENST00000611625.4; ENST00000261769.10; ENST00000621016.4; ENST00000566510.5; ENST00000566612.5; ENST00000422392.6; ENST00000562836.5
External Link	RMBase: m6A_site_327642
mod ID: M6ASITE027984		Click to Show/Hide the Full List
mod site	chr16:68763371-68763372:+		[15]
Sequence	ATTTCAGCTGGGAAAATGGGACAGGAGCCTTGGGAGTGGGT
Motif Score	3.643047619
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000261769.10; ENST00000611625.4; ENST00000621016.4; ENST00000566510.5; ENST00000422392.6; ENST00000566612.5; ENST00000562836.5; ENST00000612417.4
External Link	RMBase: m6A_site_327643
mod ID: M6ASITE027985		Click to Show/Hide the Full List
mod site	chr16:68771085-68771086:+		[15]
Sequence	GATTCTCATTTCTTCCATGGACACGGCTAAGTGCGGGCTGG
Motif Score	3.643047619
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000261769.10; ENST00000612417.4; ENST00000564745.1; ENST00000562836.5; ENST00000422392.6; ENST00000611625.4; ENST00000621016.4; ENST00000564676.5; ENST00000566510.5; ENST00000566612.5
External Link	RMBase: m6A_site_327644
mod ID: M6ASITE027986		Click to Show/Hide the Full List
mod site	chr16:68801701-68801702:+		[15]
Sequence	ATTGCACCGGTCGACAAAGGACAGCCTATTTTTCCCTCGAC
Motif Score	3.643047619
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000422392.6; ENST00000562836.5; ENST00000621016.4; ENST00000566612.5; ENST00000261769.10; ENST00000564676.5; ENST00000566510.5; ENST00000612417.4; ENST00000564745.1; ENST00000611625.4
External Link	RMBase: m6A_site_327645
mod ID: M6ASITE027987		Click to Show/Hide the Full List
mod site	chr16:68801755-68801756:+		[16]
Sequence	TGGGCACAGATGGTGTGATTACAGTCAAAAGGCCTCTACGG
Motif Score	2.07285119
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000621016.4; ENST00000612417.4; ENST00000561751.1; ENST00000564745.1; ENST00000562836.5; ENST00000566510.5; ENST00000566612.5; ENST00000422392.6; ENST00000564676.5; ENST00000261769.10; ENST00000611625.4
External Link	RMBase: m6A_site_327646
mod ID: M6ASITE027988		Click to Show/Hide the Full List
mod site	chr16:68801787-68801788:+		[16]
Sequence	CCTCTACGGTTTCATAACCCACAGATCCATTTCTTGGTCTA
Motif Score	2.053113095
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000561751.1; ENST00000564745.1; ENST00000261769.10; ENST00000621016.4; ENST00000566612.5; ENST00000612417.4; ENST00000566510.5; ENST00000422392.6; ENST00000564676.5; ENST00000562836.5; ENST00000611625.4
External Link	RMBase: m6A_site_327647
mod ID: M6ASITE027989		Click to Show/Hide the Full List
mod site	chr16:68801816-68801817:+		[17]
Sequence	TTTCTTGGTCTACGCCTGGGACTCCACCTACAGAAAGTTTT
Motif Score	4.065041667
Cell/Tissue List	Huh7; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000611625.4; ENST00000566612.5; ENST00000566510.5; ENST00000561751.1; ENST00000621016.4; ENST00000564676.5; ENST00000562836.5; ENST00000261769.10; ENST00000422392.6; ENST00000612417.4; ENST00000564745.1
External Link	RMBase: m6A_site_327648
mod ID: M6ASITE027990		Click to Show/Hide the Full List
mod site	chr16:68801825-68801826:+		[16]
Sequence	CTACGCCTGGGACTCCACCTACAGAAAGTTTTCCACCAAAG
Motif Score	2.078666667
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000621016.4; ENST00000611625.4; ENST00000562836.5; ENST00000564676.5; ENST00000612417.4; ENST00000422392.6; ENST00000566510.5; ENST00000261769.10; ENST00000564745.1; ENST00000561751.1; ENST00000566612.5
External Link	RMBase: m6A_site_327649
mod ID: M6ASITE027992		Click to Show/Hide the Full List
mod site	chr16:68808488-68808489:+		[15]
Sequence	TCCTCTCCTGGCCTCAGAAGACAGAAGAGAGACTGGGTTAT
Motif Score	2.897386905
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000561751.1; ENST00000562836.5; ENST00000566510.5; ENST00000261769.10; ENST00000611625.4; ENST00000621016.4; ENST00000422392.6; ENST00000564676.5; ENST00000566612.5; ENST00000612417.4; ENST00000564745.1
External Link	RMBase: m6A_site_327650
mod ID: M6ASITE027993		Click to Show/Hide the Full List
mod site	chr16:68808499-68808500:+		[15]
Sequence	CCTCAGAAGACAGAAGAGAGACTGGGTTATTCCTCCCATCA
Motif Score	3.319380952
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000621016.4; ENST00000562836.5; ENST00000564745.1; ENST00000566612.5; ENST00000261769.10; ENST00000612417.4; ENST00000564676.5; ENST00000422392.6; ENST00000561751.1; ENST00000611625.4; ENST00000566510.5
External Link	RMBase: m6A_site_327651
mod ID: M6ASITE027994		Click to Show/Hide the Full List
mod site	chr16:68808556-68808557:+		[15]
Sequence	AAAAGGCCCATTTCCTAAAAACCTGGTTCAGGTAGAGAAAG
Motif Score	2.185083333
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000612417.4; ENST00000261769.10; ENST00000566510.5; ENST00000611625.4; ENST00000422392.6; ENST00000561751.1; ENST00000564676.5; ENST00000621016.4; ENST00000567320.1; ENST00000562836.5; ENST00000566612.5; ENST00000564745.1
External Link	RMBase: m6A_site_327652
mod ID: M6ASITE027995		Click to Show/Hide the Full List
mod site	chr16:68808708-68808709:+		[15]
Sequence	TCAGATCAAATCCAACAAAGACAAAGAAGGCAAGGTTTTCT
Motif Score	2.897386905
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000612417.4; ENST00000261769.10; ENST00000562836.5; ENST00000621016.4; ENST00000611625.4; ENST00000564745.1; ENST00000567320.1; ENST00000566510.5; ENST00000564676.5; ENST00000422392.6; ENST00000561751.1; ENST00000566612.5
External Link	RMBase: m6A_site_327653
mod ID: M6ASITE027996		Click to Show/Hide the Full List
mod site	chr16:68808791-68808792:+		[15]
Sequence	TCTTTATTATTGAAAGAGAAACAGGATGGCTGAAGGTGACA
Motif Score	2.20572619
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000567320.1; ENST00000612417.4; ENST00000566612.5; ENST00000422392.6; ENST00000566510.5; ENST00000621016.4; ENST00000562836.5; ENST00000261769.10; ENST00000611625.4; ENST00000561751.1; ENST00000564676.5
External Link	RMBase: m6A_site_327654
mod ID: M6ASITE027997		Click to Show/Hide the Full List
mod site	chr16:68811685-68811686:+		[17]
Sequence	CTCCTTGAACTCTTCCAGGAACCTCTGTGATGGAGGTCACA
Motif Score	2.930744048
Cell/Tissue List	Huh7; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000566510.5; ENST00000566612.5; ENST00000261769.10; ENST00000562836.5; ENST00000422392.6; ENST00000612417.4; ENST00000611625.4; ENST00000621016.4; ENST00000561751.1
External Link	RMBase: m6A_site_327655
mod ID: M6ASITE027998		Click to Show/Hide the Full List
mod site	chr16:68811731-68811732:+		[17]
Sequence	AGACGCGGACGATGATGTGAACACCTACAATGCCGCCATCG
Motif Score	2.951386905
Cell/Tissue List	Huh7; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000561751.1; ENST00000261769.10; ENST00000621016.4; ENST00000611625.4; ENST00000566510.5; ENST00000562836.5; ENST00000566612.5; ENST00000422392.6; ENST00000612417.4
External Link	RMBase: m6A_site_327656
mod ID: M6ASITE027999		Click to Show/Hide the Full List
mod site	chr16:68811815-68811816:+		[15]
Sequence	TATGTTCACCATTAACAGGAACACAGGAGTCATCAGTGTGG
Motif Score	2.951386905
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000422392.6; ENST00000261769.10; ENST00000561751.1; ENST00000566612.5; ENST00000566510.5; ENST00000612417.4; ENST00000621016.4; ENST00000611625.4; ENST00000562836.5
External Link	RMBase: m6A_site_327657
mod ID: M6ASITE028000		Click to Show/Hide the Full List
mod site	chr16:68811851-68811852:+		[15]
Sequence	TGTGGTCACCACTGGGCTGGACCGAGAGGTCAGGGGTCAGG
Motif Score	3.622404762
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000611625.4; ENST00000562836.5; ENST00000566510.5; ENST00000566612.5; ENST00000621016.4; ENST00000261769.10; ENST00000561751.1; ENST00000422392.6; ENST00000612417.4
External Link	RMBase: m6A_site_327658
mod ID: M6ASITE028001		Click to Show/Hide the Full List
mod site	chr16:68815686-68815687:+		[15]
Sequence	GAGAGTGGAAGTGTCCGAGGACTTTGGCGTGGGCCAGGAAA
Motif Score	4.065041667
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000611625.4; ENST00000261769.10; ENST00000566612.5; ENST00000621016.4; ENST00000566510.5; ENST00000612417.4; ENST00000422392.6; ENST00000562836.5
External Link	RMBase: m6A_site_327659
mod ID: M6ASITE028003		Click to Show/Hide the Full List
mod site	chr16:68815734-68815735:+		[15]
Sequence	CTACACTGCCCAGGAGCCAGACACATTTATGGAACAGAAAA
Motif Score	2.897386905
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000422392.6; ENST00000611625.4; ENST00000612417.4; ENST00000562836.5; ENST00000566612.5; ENST00000261769.10; ENST00000621016.4; ENST00000566510.5
External Link	RMBase: m6A_site_327660
mod ID: M6ASITE028004		Click to Show/Hide the Full List
mod site	chr16:68815747-68815748:+		[15]
Sequence	GAGCCAGACACATTTATGGAACAGAAAATAACGTAAGTGTG
Motif Score	2.951386905
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000612417.4; ENST00000566612.5; ENST00000261769.10; ENST00000611625.4; ENST00000621016.4; ENST00000422392.6; ENST00000566510.5; ENST00000562836.5
External Link	RMBase: m6A_site_327661
mod ID: M6ASITE028005		Click to Show/Hide the Full List
mod site	chr16:68819296-68819297:+		[15]
Sequence	CAGATATCGGATTTGGAGAGACACTGCCAACTGGCTGGAGA
Motif Score	2.897386905
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000261769.10; ENST00000422392.6; ENST00000562836.5; ENST00000566510.5; ENST00000566612.5; ENST00000621016.4; ENST00000612417.4; ENST00000611625.4
External Link	RMBase: m6A_site_327662
mod ID: M6ASITE028006		Click to Show/Hide the Full List
mod site	chr16:68819326-68819327:+		[15]
Sequence	CTGGCTGGAGATTAATCCGGACACTGGTGCCATTTCCACTC
Motif Score	3.643047619
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000422392.6; ENST00000562836.5; ENST00000611625.4; ENST00000261769.10; ENST00000566612.5; ENST00000621016.4; ENST00000566510.5; ENST00000612417.4
External Link	RMBase: m6A_site_327663
mod ID: M6ASITE028007		Click to Show/Hide the Full List
mod site	chr16:68819359-68819360:+		[15]
Sequence	TTCCACTCGGGCTGAGCTGGACAGGGAGGATTTTGAGCACG
Motif Score	3.643047619
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000566510.5; ENST00000261769.10; ENST00000612417.4; ENST00000422392.6; ENST00000621016.4; ENST00000566612.5; ENST00000611625.4; ENST00000562836.5
External Link	RMBase: m6A_site_327664
mod ID: M6ASITE028008		Click to Show/Hide the Full List
mod site	chr16:68819386-68819387:+		[17]
Sequence	GGATTTTGAGCACGTGAAGAACAGCACGTACACAGCCCTAA
Motif Score	2.951386905
Cell/Tissue List	Huh7; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000566612.5; ENST00000422392.6; ENST00000612417.4; ENST00000611625.4; ENST00000566510.5; ENST00000562836.5; ENST00000621016.4; ENST00000261769.10
External Link	RMBase: m6A_site_327665
mod ID: M6ASITE028009		Click to Show/Hide the Full List
mod site	chr16:68819419-68819420:+		[17]
Sequence	AGCCCTAATCATAGCTACAGACAATGGTAAGGGGGCCTCAT
Motif Score	2.897386905
Cell/Tissue List	Huh7; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000611625.4; ENST00000621016.4; ENST00000562836.5; ENST00000612417.4; ENST00000566612.5; ENST00000261769.10; ENST00000566510.5; ENST00000422392.6
External Link	RMBase: m6A_site_327666
mod ID: M6ASITE028010		Click to Show/Hide the Full List
mod site	chr16:68822020-68822021:+		[17]
Sequence	GTTCTCCAGTTGCTACTGGAACAGGGACACTTCTGCTGATC
Motif Score	2.951386905
Cell/Tissue List	Huh7; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000261769.10; ENST00000562836.5; ENST00000612417.4; ENST00000566612.5; ENST00000422392.6; ENST00000566510.5; ENST00000611625.4; ENST00000621016.4
External Link	RMBase: m6A_site_327667
mod ID: M6ASITE028011		Click to Show/Hide the Full List
mod site	chr16:68822026-68822027:+		[17]
Sequence	CAGTTGCTACTGGAACAGGGACACTTCTGCTGATCCTGTCT
Motif Score	3.643047619
Cell/Tissue List	Huh7; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000562836.5; ENST00000612417.4; ENST00000422392.6; ENST00000566510.5; ENST00000611625.4; ENST00000261769.10; ENST00000566612.5; ENST00000621016.4
External Link	RMBase: m6A_site_327668
mod ID: M6ASITE028012		Click to Show/Hide the Full List
mod site	chr16:68822076-68822077:+		[15]
Sequence	GACAACGCCCCCATACCAGAACCTCGAACTATATTCTTCTG
Motif Score	2.930744048
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000566510.5; ENST00000611625.4; ENST00000562836.5; ENST00000261769.10; ENST00000612417.4; ENST00000566612.5; ENST00000621016.4; ENST00000422392.6
External Link	RMBase: m6A_site_327669
mod ID: M6ASITE028014		Click to Show/Hide the Full List
mod site	chr16:68822083-68822084:+		[15]
Sequence	CCCCCATACCAGAACCTCGAACTATATTCTTCTGTGAGAGG
Motif Score	3.373380952
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000261769.10; ENST00000611625.4; ENST00000566612.5; ENST00000422392.6; ENST00000562836.5; ENST00000566510.5; ENST00000612417.4; ENST00000621016.4
External Link	RMBase: m6A_site_327670
mod ID: M6ASITE028015		Click to Show/Hide the Full List
mod site	chr16:68822126-68822127:+		[16]
Sequence	TCCAAAGCCTCAGGTCATAAACATCATTGATGCAGACCTTC
Motif Score	2.20572619
Cell/Tissue List	liver; Huh7; HEC-1-A
Seq Type List	m6A-REF-seq; MeRIP-seq; m6A-seq
Transcript ID List	ENST00000611625.4; ENST00000422392.6; ENST00000261769.10; ENST00000621016.4; ENST00000566510.5; ENST00000612417.4; ENST00000562836.5; ENST00000566612.5
External Link	RMBase: m6A_site_327671
mod ID: M6ASITE028016		Click to Show/Hide the Full List
mod site	chr16:68822141-68822142:+		[18]
Sequence	CATAAACATCATTGATGCAGACCTTCCTCCCAATACATCTC
Motif Score	2.876744048
Cell/Tissue List	fibroblasts; Huh7; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000621016.4; ENST00000611625.4; ENST00000422392.6; ENST00000566510.5; ENST00000566612.5; ENST00000612417.4; ENST00000261769.10; ENST00000562836.5
External Link	RMBase: m6A_site_327672
mod ID: M6ASITE028017		Click to Show/Hide the Full List
mod site	chr16:68822175-68822176:+		[18]
Sequence	ACATCTCCCTTCACAGCAGAACTAACACACGGGGCGAGTGC
Motif Score	3.373380952
Cell/Tissue List	fibroblasts; Huh7; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000566510.5; ENST00000612417.4; ENST00000261769.10; ENST00000611625.4; ENST00000621016.4; ENST00000422392.6; ENST00000566612.5; ENST00000562836.5
External Link	RMBase: m6A_site_327673
mod ID: M6ASITE028018		Click to Show/Hide the Full List
mod site	chr16:68822203-68822204:+		[18]
Sequence	ACGGGGCGAGTGCCAACTGGACCATTCAGTACAACGACCCA
Motif Score	3.622404762
Cell/Tissue List	fibroblasts; Huh7; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000611625.4; ENST00000612417.4; ENST00000261769.10; ENST00000562836.5; ENST00000621016.4; ENST00000422392.6; ENST00000566612.5; ENST00000566510.5
External Link	RMBase: m6A_site_327674
mod ID: M6ASITE028019		Click to Show/Hide the Full List
mod site	chr16:68822794-68822795:+		[13]
Sequence	GTGTCCCTTGAAAATGCAAAACCAGTGTGGCGGCCGCACTG
Motif Score	2.185083333
Cell/Tissue List	H1B; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000562836.5; ENST00000562087.2; ENST00000566612.5; ENST00000422392.6; ENST00000621016.4; ENST00000612417.4; ENST00000611625.4; ENST00000261769.10; ENST00000566510.5
External Link	RMBase: m6A_site_327675
mod ID: M6ASITE028020		Click to Show/Hide the Full List
mod site	chr16:68822824-68822825:+		[13]
Sequence	CGGCCGCACTGTCTTCCCGGACATCCAGAAGCCATGTAAAG
Motif Score	3.643047619
Cell/Tissue List	H1A; H1B; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000566510.5; ENST00000621016.4; ENST00000562836.5; ENST00000612417.4; ENST00000562087.2; ENST00000566612.5; ENST00000611625.4; ENST00000261769.10; ENST00000422392.6
External Link	RMBase: m6A_site_327676
mod ID: M6ASITE028021		Click to Show/Hide the Full List
mod site	chr16:68822859-68822860:+		[13]
Sequence	GTAAAGATGAATGGGGTAAAACCCTGGGTGCGATGGAAGTC
Motif Score	2.185083333
Cell/Tissue List	H1A; H1B; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000422392.6; ENST00000261769.10; ENST00000562836.5; ENST00000566510.5; ENST00000621016.4; ENST00000562087.2; ENST00000612417.4; ENST00000566612.5; ENST00000611625.4
External Link	RMBase: m6A_site_327677
mod ID: M6ASITE028022		Click to Show/Hide the Full List
mod site	chr16:68822899-68822900:+		[13]
Sequence	CACTCTGGCCCTGGAGAAGAACCTGAACTGGACCCTTTTGG
Motif Score	2.930744048
Cell/Tissue List	H1A; H1B; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000566612.5; ENST00000621016.4; ENST00000611625.4; ENST00000566510.5; ENST00000612417.4; ENST00000562836.5; ENST00000562087.2; ENST00000261769.10; ENST00000422392.6
External Link	RMBase: m6A_site_327678
mod ID: M6ASITE028023		Click to Show/Hide the Full List
mod site	chr16:68822905-68822906:+		[13]
Sequence	GGCCCTGGAGAAGAACCTGAACTGGACCCTTTTGGATCTTC
Motif Score	3.373380952
Cell/Tissue List	H1A; H1B; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000611625.4; ENST00000261769.10; ENST00000566510.5; ENST00000562087.2; ENST00000562836.5; ENST00000566612.5; ENST00000422392.6; ENST00000612417.4; ENST00000621016.4
External Link	RMBase: m6A_site_327679
mod ID: M6ASITE028025		Click to Show/Hide the Full List
mod site	chr16:68822910-68822911:+		[13]
Sequence	TGGAGAAGAACCTGAACTGGACCCTTTTGGATCTTCATGCC
Motif Score	3.622404762
Cell/Tissue List	H1A; H1B; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000621016.4; ENST00000612417.4; ENST00000611625.4; ENST00000566510.5; ENST00000261769.10; ENST00000562087.2; ENST00000562836.5; ENST00000422392.6; ENST00000566612.5
External Link	RMBase: m6A_site_327680
mod ID: M6ASITE028026		Click to Show/Hide the Full List
mod site	chr16:68822950-68822951:+		[13]
Sequence	CTTGGGTTCCACCTGCACAGACCCCCATATCTGTGACTTCC
Motif Score	2.876744048
Cell/Tissue List	H1A; H1B; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000562087.2; ENST00000566612.5; ENST00000621016.4; ENST00000566510.5; ENST00000612417.4; ENST00000422392.6; ENST00000562836.5; ENST00000261769.10; ENST00000611625.4
External Link	RMBase: m6A_site_327681
mod ID: M6ASITE028027		Click to Show/Hide the Full List
mod site	chr16:68823002-68823003:+		[13]
Sequence	TTCCTAGATGAAAAAGTAAAACTCATCAAGAAGATAGGTGA
Motif Score	2.627720238
Cell/Tissue List	H1A; H1B
Seq Type List	m6A-seq
Transcript ID List	ENST00000261769.10; ENST00000611625.4; ENST00000621016.4; ENST00000566612.5; ENST00000562087.2; ENST00000562836.5; ENST00000422392.6; ENST00000612417.4; ENST00000566510.5
External Link	RMBase: m6A_site_327682
mod ID: M6ASITE028028		Click to Show/Hide the Full List
mod site	chr16:68823272-68823273:+		[18]
Sequence	AAAGTACATACCTAAATAAAACCCAAGCAGCTCTGCTCTCT
Motif Score	2.185083333
Cell/Tissue List	fibroblasts; Huh7; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000621016.4; ENST00000566510.5; ENST00000612417.4; ENST00000422392.6; ENST00000562836.5; ENST00000611625.4; ENST00000261769.10; ENST00000566612.5; ENST00000562118.1
External Link	RMBase: m6A_site_327683
mod ID: M6ASITE028029		Click to Show/Hide the Full List
mod site	chr16:68823488-68823489:+		[15]
Sequence	CATGGATAACCAGAATAAAGACCAAGTGACCACCTTAGAGG
Motif Score	2.876744048
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000566612.5; ENST00000566510.5; ENST00000422392.6; ENST00000562836.5; ENST00000261769.10; ENST00000612417.4; ENST00000562118.1; ENST00000611625.4; ENST00000621016.4
External Link	RMBase: m6A_site_327685
mod ID: M6ASITE028030		Click to Show/Hide the Full List
mod site	chr16:68826548-68826549:+		[15]
Sequence	GAGGTGGCAGGATTGCTTGAACCTAGGTTTCAAGATCAGCC
Motif Score	2.930744048
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000422392.6; ENST00000566612.5; ENST00000562118.1; ENST00000562836.5; ENST00000621016.4; rmsk_4566307; ENST00000612417.4; ENST00000261769.10; ENST00000611625.4; ENST00000566510.5
External Link	RMBase: m6A_site_327686
mod ID: M6ASITE028031		Click to Show/Hide the Full List
mod site	chr16:68828257-68828258:+		[15]
Sequence	CCCAGAGGATGACACCCGGGACAACGTTTATTACTATGATG
Motif Score	3.643047619
Cell/Tissue List	endometrial; HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000566612.5; ENST00000562118.1; ENST00000261769.10; ENST00000566510.5; ENST00000612417.4; ENST00000422392.6; ENST00000562836.5; ENST00000621016.4; ENST00000611625.4
External Link	RMBase: m6A_site_327687
mod ID: M6ASITE028032		Click to Show/Hide the Full List
mod site	chr16:68828299-68828300:+		[15]
Sequence	AGAAGGAGGCGGAGAAGAGGACCAGGTGGGTTTTGAAAACC
Motif Score	3.622404762
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000621016.4; ENST00000566510.5; ENST00000422392.6; ENST00000562118.1; ENST00000612417.4; ENST00000261769.10; ENST00000611625.4; ENST00000562836.5; ENST00000566612.5
External Link	RMBase: m6A_site_327688
mod ID: M6ASITE028033		Click to Show/Hide the Full List
mod site	chr16:68829675-68829676:+		[16]
Sequence	CTTTGACTTGAGCCAGCTGCACAGGGGCCTGGACGCTCGGC
Motif Score	2.830589286
Cell/Tissue List	liver
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000422392.6; ENST00000566612.5; ENST00000621016.4; ENST00000566510.5; ENST00000562836.5; ENST00000261769.10; ENST00000562118.1; ENST00000611625.4; ENST00000612417.4
External Link	RMBase: m6A_site_327689
mod ID: M6ASITE028035		Click to Show/Hide the Full List
mod site	chr16:68833395-68833396:+		[14]
Sequence	TGCTAGTCTGAGCTCCCTGAACTCCTCAGAGTCAGACAAAG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hESCs; fibroblasts; GM12878; Huh7; CD4T; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000611625.4; ENST00000562836.5; ENST00000261769.10; ENST00000422392.6; ENST00000562118.1; ENST00000612417.4; ENST00000566612.5; ENST00000621016.4; ENST00000566510.5
External Link	RMBase: m6A_site_327690
mod ID: M6ASITE028036		Click to Show/Hide the Full List
mod site	chr16:68833410-68833411:+		[14]
Sequence	CCTGAACTCCTCAGAGTCAGACAAAGACCAGGACTATGACT
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hESCs; fibroblasts; GM12878; Huh7; CD4T; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000621016.4; ENST00000566612.5; ENST00000611625.4; ENST00000612417.4; ENST00000422392.6; ENST00000562118.1; ENST00000562836.5; ENST00000261769.10; ENST00000566510.5
External Link	RMBase: m6A_site_327691
mod ID: M6ASITE028037		Click to Show/Hide the Full List
mod site	chr16:68833416-68833417:+		[14]
Sequence	CTCCTCAGAGTCAGACAAAGACCAGGACTATGACTACTTGA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hESCs; fibroblasts; GM12878; Huh7; CD4T; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000261769.10; ENST00000566510.5; ENST00000566612.5; ENST00000612417.4; ENST00000621016.4; ENST00000611625.4; ENST00000422392.6; ENST00000562118.1; ENST00000562836.5
External Link	RMBase: m6A_site_327692
mod ID: M6ASITE028038		Click to Show/Hide the Full List
mod site	chr16:68833422-68833423:+		[14]
Sequence	AGAGTCAGACAAAGACCAGGACTATGACTACTTGAACGAAT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hESCs; fibroblasts; GM12878; Huh7; CD4T; iSLK; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000621016.4; ENST00000562836.5; ENST00000562118.1; ENST00000566510.5; ENST00000611625.4; ENST00000566612.5; ENST00000612417.4; ENST00000261769.10; ENST00000422392.6
External Link	RMBase: m6A_site_327693
mod ID: M6ASITE028039		Click to Show/Hide the Full List
mod site	chr16:68833491-68833492:+		[19]
Sequence	CATGTACGGAGGCGGCGAGGACGACTAGGGGACTCGAGAGA
Motif Score	3.616982143
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000422392.6; ENST00000562836.5; ENST00000621016.4; ENST00000562118.1; ENST00000566510.5; ENST00000611625.4; ENST00000261769.10; ENST00000612417.4; ENST00000566612.5
External Link	RMBase: m6A_site_327694
mod ID: M6ASITE028040		Click to Show/Hide the Full List
mod site	chr16:68833502-68833503:+		[14]
Sequence	GCGGCGAGGACGACTAGGGGACTCGAGAGAGGCGGGCCCCA
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; Huh7; CD4T; iSLK; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000621016.4; ENST00000566510.5; ENST00000562836.5; ENST00000566612.5; ENST00000562118.1; ENST00000611625.4; ENST00000612417.4; ENST00000261769.10; ENST00000422392.6
External Link	RMBase: m6A_site_327695
mod ID: M6ASITE028041		Click to Show/Hide the Full List
mod site	chr16:68833524-68833525:+		[20]
Sequence	TCGAGAGAGGCGGGCCCCAGACCCATGTGCTGGGAAATGCA
Motif Score	2.876744048
Cell/Tissue List	HepG2; HEK293T; A549; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; Huh7; iSLK; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000566510.5; ENST00000612417.4; ENST00000562118.1; ENST00000566612.5; ENST00000261769.10; ENST00000562836.5; ENST00000621016.4; ENST00000611625.4; ENST00000422392.6
External Link	RMBase: m6A_site_327696
mod ID: M6ASITE028042		Click to Show/Hide the Full List
mod site	chr16:68833612-68833613:+		[20]
Sequence	TTTCTGGGGAAAAAAAAGAGACTGGTTAGTGATGCAGTTAG
Motif Score	3.319380952
Cell/Tissue List	HepG2; HEK293T; A549; H1A; H1B; hESCs; fibroblasts; Huh7; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000612417.4; ENST00000621016.4; ENST00000566612.5; ENST00000611625.4; ENST00000261769.10
External Link	RMBase: m6A_site_327697
mod ID: M6ASITE028043		Click to Show/Hide the Full List
mod site	chr16:68833782-68833783:+		[17]
Sequence	AATTTTAATATTCCAGAAGAACAACTTTAGCATCAGAAGGT
Motif Score	2.951386905
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000612417.4; ENST00000611625.4; ENST00000261769.10; ENST00000566612.5; ENST00000621016.4
External Link	RMBase: m6A_site_327698
mod ID: M6ASITE028044		Click to Show/Hide the Full List
mod site	chr16:68834797-68834798:+		[21]
Sequence	CAAGAGTGATATACTCCAGGACTTAGAATAGTGCCTAAAGT
Motif Score	4.065041667
Cell/Tissue List	HEK293T; H1A; H1B; hESCs; fibroblasts; A549; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq; m6A-CLIP/IP
Transcript ID List	ENST00000621016.4; ENST00000566612.5; ENST00000261769.10; ENST00000611625.4
External Link	RMBase: m6A_site_327699
mod ID: M6ASITE028046		Click to Show/Hide the Full List
mod site	chr16:68834831-68834832:+		[22]
Sequence	CTAAAGTGCTGCAGCCAAAGACAGAGCGGAACTATGAAAAG
Motif Score	2.897386905
Cell/Tissue List	HEK293T; hESC-HEK293T; H1A; H1B; hESCs; fibroblasts; A549; HEC-1-A
Seq Type List	MeRIP-seq; MAZTER-seq; m6A-seq; m6A-CLIP/IP
Transcript ID List	ENST00000621016.4; ENST00000566612.5; ENST00000611625.4; ENST00000261769.10
External Link	RMBase: m6A_site_327700
mod ID: M6ASITE028047		Click to Show/Hide the Full List
mod site	chr16:68834841-68834842:+		[21]
Sequence	GCAGCCAAAGACAGAGCGGAACTATGAAAAGTGGGCTTGGA
Motif Score	3.373380952
Cell/Tissue List	HEK293T; H1A; H1B; hESCs; fibroblasts; A549; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000621016.4; ENST00000566612.5; ENST00000611625.4; ENST00000261769.10
External Link	RMBase: m6A_site_327701
mod ID: M6ASITE028048		Click to Show/Hide the Full List
mod site	chr16:68834903-68834904:+		[23]
Sequence	TGAGCCTGGCAATTTAGCAAACTGATGCTGAGGATGATTGA
Motif Score	2.627720238
Cell/Tissue List	A549; H1A; H1B; hESCs; fibroblasts; HEC-1-A
Seq Type List	MeRIP-seq; m6A-seq
Transcript ID List	ENST00000261769.10; ENST00000611625.4; ENST00000566612.5; ENST00000621016.4
External Link	RMBase: m6A_site_327702
mod ID: M6ASITE028049		Click to Show/Hide the Full List
mod site	chr16:68835074-68835075:+		[15]
Sequence	GAAAATGCTGGCTGAGCTGAACACATTTGCCCAATTCCAGG
Motif Score	2.951386905
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000611625.4; ENST00000261769.10; ENST00000621016.4
External Link	RMBase: m6A_site_327703
mod ID: M6ASITE028050		Click to Show/Hide the Full List
mod site	chr16:68835107-68835108:+		[15]
Sequence	ATTCCAGGTGTGCACAGAAAACCGAGAATATTCAAAATTCC
Motif Score	2.185083333
Cell/Tissue List	HEC-1-A
Seq Type List	m6A-seq
Transcript ID List	ENST00000261769.10; ENST00000621016.4; ENST00000611625.4
External Link	RMBase: m6A_site_327704
mod ID: M6ASITE028051		Click to Show/Hide the Full List
mod site	chr16:68835263-68835264:+		[18]
Sequence	TTTTGACAATCAAAGAAAAGACTTTTGTTGAAATAGCTTTA
Motif Score	3.319380952
Cell/Tissue List	fibroblasts; A549
Seq Type List	m6A-seq; m6A-CLIP/IP
Transcript ID List	ENST00000611625.4; ENST00000261769.10; ENST00000621016.4
External Link	RMBase: m6A_site_327705

Ref 1	N6-Methyladenosine Modification of CDH1 mRNA Promotes PM2.5-Induced Pulmonary Fibrosis via Mediating Epithelial Mesenchymal Transition. Toxicol Sci. 2022 Jan 24;185(2):143-157. doi: 10.1093/toxsci/kfab133.
Ref 2	Characterization of the role of ABCG2 as a bile acid transporter in liver and placenta. Mol Pharmacol. 2012 Feb;81(2):273-83.
Ref 3	Pharmacokinetic interaction profile of riociguat, a new soluble guanylate cyclase stimulator, in?vitro. Pulm Pharmacol Ther. 2014 Aug;28(2):130-7. doi: 10.1016/j.pupt.2014.02.004. Epub 2014 Mar 21.
Ref 4	Impact of drug transporters on cellular resistance towards saquinavir and darunavir. J Antimicrob Chemother. 2010 Nov;65(11):2319-28.
Ref 5	Nonclinical pharmacokinetics of oseltamivir and oseltamivir carboxylate in the central nervous system. Antimicrob Agents Chemother. 2009 Nov;53(11):4753-61. doi: 10.1128/AAC.01541-08. Epub 2009 Aug 31.
Ref 6	The SLC45 gene family of putative sugar transporters. Mol Aspects Med. 2013 Apr-Jun;34(2-3):655-60. doi: 10.1016/j.mam.2012.05.014.
Ref 7	Pharmacogenomic importance of ABCG2. Pharmacogenomics. 2008 Aug;9(8):1005-9.
Ref 8	L-type calcium channel blockers reverse docetaxel and vincristine-induced multidrug resistance independent of ABCB1 expression in human lung cancer cell lines. Toxicol Lett. 2010 Feb 15;192(3):408-18. doi: 10.1016/j.toxlet.2009.11.018. Epub 2009 Nov 26.
Ref 9	Opioids and efflux transporters. Part 3: P-glycoprotein substrate activity of 3-hydroxyl addition to meperidine analogs. Bioorg Med Chem Lett. 2008 Jun 15;18(12):3638-40. doi: 10.1016/j.bmcl.2008.04.046. Epub 2008 Apr 25.
Ref 10	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 11	Accurate identification of A-to-I RNA editing in human by transcriptome sequencing. Genome Res. 2012 Jan;22(1):142-50. doi: 10.1101/gr.124107.111. Epub 2011 Sep 29.
Ref 12	Identification of direct targets and modified bases of RNA cytosine methyltransferases. Nat Biotechnol. 2013 May;31(5):458-64. doi: 10.1038/nbt.2566. Epub 2013 Apr 21.
Ref 13	m(6)A RNA modification controls cell fate transition in mammalian embryonic stem cells. Cell Stem Cell. 2014 Dec 4;15(6):707-19. doi: 10.1016/j.stem.2014.09.019. Epub 2014 Oct 16.
Ref 14	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 15	m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer. Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27.
Ref 16	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 17	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 18	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10;8(1):284-96. doi: 10.1016/j.celrep.2014.05.048. Epub 2014 Jun 26.
Ref 19	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 20	Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13.
Ref 21	Comprehensive analysis of mRNA methylation reveals enrichment in 3' UTRs and near stop codons. Cell. 2012 Jun 22;149(7):1635-46. doi: 10.1016/j.cell.2012.05.003. Epub 2012 May 17.
Ref 22	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 23	Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus. Nat Commun. 2019 Oct 9;10(1):4595. doi: 10.1038/s41467-019-12504-y.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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