m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00559)

Target Name	Insulin receptor substrate 1 (IRS1)
Synonyms	IRS-1 Click to Show/Hide
Gene Name	IRS1
Chromosomal Location	2q36.3
Function	May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity). Click to Show/Hide
Gene ID	3667
Uniprot ID	IRS1_HUMAN
HGNC ID	HGNC:6125
KEGG ID	hsa:3667

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

IRS1 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

YTH domain-containing family protein 2 (YTHDF2) [READER]

Regulator Info

*Representative RIP-seq result supporting the interaction between IRS1 and the regulator*
Cell Line	Hela	Homo sapiens
Regulation	logFC: 1.86E+00	GSE49339

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	YTHDF2 inhibited the proliferation and invasion of endometrial cancer(EC) via inhibiting Insulin receptor substrate 1 (IRS1) expression in m6A epigenetic way, which suggests a potential therapeutic target for EC.
Target Regulation	Down regulation
Responsed Disease	Endometrial cancer		ICD-11: 2C76	Disease Info
Pathway Response	PI3K-Akt signaling pathway			hsa04151
In-vitro Model	T HESCs	Normal	Homo sapiens	CVCL_C464
	RL95-2	Endometrial adenosquamous carcinoma	Homo sapiens	CVCL_0505
	HEC-1-A	Endometrial adenocarcinoma	Homo sapiens	CVCL_0293

Endometrial cancer [ICD-11: 2C76]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[1]
Response Summary	YTHDF2 inhibited the proliferation and invasion of endometrial cancer(EC) via inhibiting Insulin receptor substrate 1 (IRS1) expression in m6A epigenetic way, which suggests a potential therapeutic target for EC.
Responsed Disease	Endometrial cancer [ICD-11: 2C76]
Target Regulator	YTH domain-containing family protein 2 (YTHDF2)		READER	Regulator Info
Target Regulation	Down regulation
Pathway Response	PI3K-Akt signaling pathway			hsa04151
In-vitro Model	T HESCs	Normal	Homo sapiens	CVCL_C464
	RL95-2	Endometrial adenosquamous carcinoma	Homo sapiens	CVCL_0505
	HEC-1-A	Endometrial adenocarcinoma	Homo sapiens	CVCL_0293

Gestational diabetes mellitus [ICD-11: JA63]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response		[]
Response Summary	Down-regulation of m6A both in the 3'-UTR and CDS near stop codons of placental mRNAs is involved in gestational diabetes mellitus(GDM) development in Han Chinese women. MazF-qPCR verified that the m6A levels of the BAMBI 3'-UTR and CDS were significantly decreased in GDM. m6A levels of GDM related genes (INSR and Insulin receptor substrate 1 (IRS1)) were significantly reduced in GDM.
Responsed Disease	Gestational diabetes mellitus [ICD-11: JA63]

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00559)

Insulin receptor substrate 1 (IRS1)

Adenosine-to-Inosine editing (A-to-I)

In total 1 m6A sequence/site(s) in this target gene
mod ID: A2ISITE010256		Click to Show/Hide the Full List
mod site	chr2:226784560-226784561:-		[3]
Sequence	ACGTGGTGGCAGGCGCCTGTAATCCCAGCTACTCGGGAGGC
Transcript ID List	ENST00000305123.5; rmsk_837286
External Link	RMBase: RNA-editing_site_83934

5-methylcytidine (m5C)

In total 4 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002518		Click to Show/Hide the Full List
mod site	chr2:226797754-226797755:-		[4]
Sequence	GGCTCCTTCCGTGTCCGCGCCTCCAGTGACGGCGAAGGCAC
Cell/Tissue List	frontalcortex
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m5C_site_27923
mod ID: M5CSITE002519		Click to Show/Hide the Full List
mod site	chr2:226799005-226799006:-		[4]
Sequence	AGACTTGGCTCTCGGAGGATCGGGGCTGCCCTCACCCCGGA
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m5C_site_27924
mod ID: M5CSITE002520		Click to Show/Hide the Full List
mod site	chr2:226799301-226799302:-
Sequence	ATTTGGGCGGCTGGTGGCGGCTGGGACGGTTGGGGGGTGGG
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m5C_site_27925
mod ID: M5CSITE002521		Click to Show/Hide the Full List
mod site	chr2:226799311-226799312:-
Sequence	CTGAGCTGGTATTTGGGCGGCTGGTGGCGGCTGGGACGGTT
Cell/Tissue List	T24
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m5C_site_27926

N6-methyladenosine (m6A)

In total 74 m6A sequence/site(s) in this target gene
mod ID: M6ASITE050370		Click to Show/Hide the Full List
mod site	chr2:226735678-226735679:-		[5]
Sequence	GAGTGGAGCAAATGCTTAAAACAAGGCTTAAAAGAGTAGAA
Motif Score	2.20572619
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513248
mod ID: M6ASITE050371		Click to Show/Hide the Full List
mod site	chr2:226735844-226735845:-		[6]
Sequence	TGTAAATTATTTCATACAAAACTGTTCACGTTGGGTGGAGA
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; A549; H1B; hESCs; fibroblasts; Huh7; iSLK; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513249
mod ID: M6ASITE050372		Click to Show/Hide the Full List
mod site	chr2:226735886-226735887:-		[6]
Sequence	ACATTTCATCTGCTGCTGAAACTGTGTACGACAAAGCATCA
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; hESCs; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513250
mod ID: M6ASITE050373		Click to Show/Hide the Full List
mod site	chr2:226735986-226735987:-		[6]
Sequence	CTTCATCTTCAACCTTAAGGACTTAGCTGGCCACAGTGAGC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; hNPCs; hESCs; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513251
mod ID: M6ASITE050374		Click to Show/Hide the Full List
mod site	chr2:226736007-226736008:-		[6]
Sequence	AGAATAATGAGTCTGCATAAACTTCATCTTCAACCTTAAGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; hNPCs; hESCs; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513252
mod ID: M6ASITE050375		Click to Show/Hide the Full List
mod site	chr2:226736032-226736033:-		[7]
Sequence	AAAAAAAAAAATGCACTGTGACACCAGAATAATGAGTCTGC
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T; A549
Seq Type List	MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513253
mod ID: M6ASITE050376		Click to Show/Hide the Full List
mod site	chr2:226736079-226736080:-		[6]
Sequence	CTCAGGATTTCATTGACTGAACTGCACGTTCTATATTGTGC
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; hNPCs; hESCs; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513254
mod ID: M6ASITE050377		Click to Show/Hide the Full List
mod site	chr2:226736084-226736085:-		[8]
Sequence	CAATCCTCAGGATTTCATTGACTGAACTGCACGTTCTATAT
Motif Score	3.28175
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513255
mod ID: M6ASITE050378		Click to Show/Hide the Full List
mod site	chr2:226736166-226736167:-		[6]
Sequence	TTTCATGATTCACAACTAGGACCTCATATCTTCCTCATCAG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; hNPCs; hESCs; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513256
mod ID: M6ASITE050379		Click to Show/Hide the Full List
mod site	chr2:226736196-226736197:-		[6]
Sequence	TCTAACTCATGGGTACCCAGACTCTAAATATTTCATGATTC
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; hNPCs; hESCs; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513257
mod ID: M6ASITE050380		Click to Show/Hide the Full List
mod site	chr2:226736212-226736213:-		[8]
Sequence	CCTCAGCAAATCCTCTTCTAACTCATGGGTACCCAGACTCT
Motif Score	2.590089286
Cell/Tissue List	A549
Seq Type List	m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513258
mod ID: M6ASITE050381		Click to Show/Hide the Full List
mod site	chr2:226736242-226736243:-		[6]
Sequence	TTTTTCTTTTCAGAATGAAGACCTAAATGACCTCAGCAAAT
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; hNPCs; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513259
mod ID: M6ASITE050382		Click to Show/Hide the Full List
mod site	chr2:226792223-226792224:-		[6]
Sequence	TGCAGCTGACAAAGACACAGACCCCAGCCATGCCTTTTGGG
Motif Score	2.876744048
Cell/Tissue List	HeLa; A549; Huh7; HEK293A-TOA; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000498335.1; ENST00000305123.5
External Link	RMBase: m6A_site_513260
mod ID: M6ASITE050383		Click to Show/Hide the Full List
mod site	chr2:226792229-226792230:-		[6]
Sequence	TGAAACTGCAGCTGACAAAGACACAGACCCCAGCCATGCCT
Motif Score	2.897386905
Cell/Tissue List	HeLa; A549; Huh7; HEK293A-TOA; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000498335.1; ENST00000305123.5
External Link	RMBase: m6A_site_513261
mod ID: M6ASITE050384		Click to Show/Hide the Full List
mod site	chr2:226792245-226792246:-		[6]
Sequence	ATTTATCTTTTAGTTTTGAAACTGCAGCTGACAAAGACACA
Motif Score	2.627720238
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5; ENST00000498335.1
External Link	RMBase: m6A_site_513262
mod ID: M6ASITE050385		Click to Show/Hide the Full List
mod site	chr2:226792305-226792306:-		[9]
Sequence	GGGCAAAAAGAGCCTCTCAGACTCGGTCATAGCAGCCCTGC
Motif Score	3.319380952
Cell/Tissue List	A549
Seq Type List	m6A-seq
Transcript ID List	ENST00000305123.5; ENST00000498335.1
External Link	RMBase: m6A_site_513263
mod ID: M6ASITE050386		Click to Show/Hide the Full List
mod site	chr2:226794999-226795000:-		[6]
Sequence	ACCGTCAGTAGCTCAACTGGACATCACAGCAGGTGCGTTTC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; A549; U2OS; hNPCs; hESCs; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5; ENST00000498335.1
External Link	RMBase: m6A_site_513264
mod ID: M6ASITE050387		Click to Show/Hide the Full List
mod site	chr2:226795019-226795020:-		[6]
Sequence	TTTCCAGAAGCAGCCAGAGGACCGTCAGTAGCTCAACTGGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; A549; U2OS; hNPCs; hESCs; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5; ENST00000498335.1
External Link	RMBase: m6A_site_513265
mod ID: M6ASITE050388		Click to Show/Hide the Full List
mod site	chr2:226795144-226795145:-		[6]
Sequence	CCTCAGGAGTGCACCCCTGAACCGCAGCCTCCCCCACCCCC
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5; ENST00000498335.1
External Link	RMBase: m6A_site_513266
mod ID: M6ASITE050389		Click to Show/Hide the Full List
mod site	chr2:226795171-226795172:-		[6]
Sequence	GATTTGGTCAAGGACTTCAAACAGTGCCCTCAGGAGTGCAC
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5; ENST00000498335.1
External Link	RMBase: m6A_site_513267
mod ID: M6ASITE050390		Click to Show/Hide the Full List
mod site	chr2:226795178-226795179:-		[6]
Sequence	AGACCTGGATTTGGTCAAGGACTTCAAACAGTGCCCTCAGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MT4; H1299; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5; ENST00000498335.1
External Link	RMBase: m6A_site_513268
mod ID: M6ASITE050391		Click to Show/Hide the Full List
mod site	chr2:226795196-226795197:-		[6]
Sequence	GAATGGTCTTAACTACATAGACCTGGATTTGGTCAAGGACT
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; MT4; H1299; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000498335.1; ENST00000305123.5
External Link	RMBase: m6A_site_513269
mod ID: M6ASITE050392		Click to Show/Hide the Full List
mod site	chr2:226795243-226795244:-		[6]
Sequence	GCCCCCAAGGAGCCAGCCAAACTGTGTGGGGCTGCTGGGGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5; ENST00000498335.1
External Link	RMBase: m6A_site_513270
mod ID: M6ASITE050393		Click to Show/Hide the Full List
mod site	chr2:226795431-226795432:-		[6]
Sequence	GGCGGAGGCATAGCTCCGAGACTTTCTCCTCAACACCCAGT
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513271
mod ID: M6ASITE050394		Click to Show/Hide the Full List
mod site	chr2:226795466-226795467:-		[6]
Sequence	TGCCAAAGTGATCCGTGCAGACCCACAAGGGTGCCGGCGGA
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513272
mod ID: M6ASITE050395		Click to Show/Hide the Full List
mod site	chr2:226795511-226795512:-		[6]
Sequence	GAGCGCCTTCACCCGGGTGAACCTCAGTCCTAACCGCAACC
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513273
mod ID: M6ASITE050396		Click to Show/Hide the Full List
mod site	chr2:226795543-226795544:-		[6]
Sequence	CTGCTGGGGGGCCCACAAGGACCTGGGGGCATGAGCGCCTT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513274
mod ID: M6ASITE050397		Click to Show/Hide the Full List
mod site	chr2:226795689-226795690:-		[6]
Sequence	TAAGCTATGCTGACATGCGAACAGGCATTGCTGCAGAGGAG
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513275
mod ID: M6ASITE050398		Click to Show/Hide the Full List
mod site	chr2:226795730-226795731:-		[6]
Sequence	TCCCCGTCAGAGCTACGTGGACACCTCGCCAGCTGCCCCTG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513276
mod ID: M6ASITE050399		Click to Show/Hide the Full List
mod site	chr2:226795846-226795847:-		[6]
Sequence	ACTGGGGTCGAGATGGGCAGACTGGGCCCTGCACCTCCCGG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513277
mod ID: M6ASITE050400		Click to Show/Hide the Full List
mod site	chr2:226795904-226795905:-		[6]
Sequence	TGAGGAGTACATGAAGATGGACCTGGGGCCGGGCCGGAGGG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513278
mod ID: M6ASITE050401		Click to Show/Hide the Full List
mod site	chr2:226795932-226795933:-		[6]
Sequence	CAGCTCCCAGAGAGGAAGAGACTGGCACTGAGGAGTACATG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513279
mod ID: M6ASITE050402		Click to Show/Hide the Full List
mod site	chr2:226796187-226796188:-		[6]
Sequence	AGGTGGACACAGCTGCTCAGACCAATAGCCGCCTGGCCCGG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; U2OS; A549; HEK293A-TOA; iSLK; MSC; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513280
mod ID: M6ASITE050403		Click to Show/Hide the Full List
mod site	chr2:226796201-226796202:-		[6]
Sequence	CCATCTGCCTCGAAAGGTGGACACAGCTGCTCAGACCAATA
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; A549; HEK293A-TOA; iSLK; MSC; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513281
mod ID: M6ASITE050404		Click to Show/Hide the Full List
mod site	chr2:226796474-226796475:-		[6]
Sequence	CTGCTACTACGGCCCTGAGGACCCCCAGCACAAGCCAGTCC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1B; hESCs; Huh7; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513282
mod ID: M6ASITE050405		Click to Show/Hide the Full List
mod site	chr2:226796513-226796514:-		[7]
Sequence	GTCACCAGTGGGGGACTCCAACACCAGCAGCCCCTCCGACT
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T; A549
Seq Type List	MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513283
mod ID: M6ASITE050406		Click to Show/Hide the Full List
mod site	chr2:226796519-226796520:-		[6]
Sequence	GAACATGTCACCAGTGGGGGACTCCAACACCAGCAGCCCCT
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513284
mod ID: M6ASITE050407		Click to Show/Hide the Full List
mod site	chr2:226796537-226796538:-		[6]
Sequence	TTGCACAGGTGACTACATGAACATGTCACCAGTGGGGGACT
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; Huh7; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513285
mod ID: M6ASITE050408		Click to Show/Hide the Full List
mod site	chr2:226796593-226796594:-		[6]
Sequence	CATGTCTTGCCTCACCCCAAACCCCCAGTGGAGAGCAGCGG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1B; H1A; hNPCs; hESCs; fibroblasts; GM12878; Huh7; Jurkat; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513286
mod ID: M6ASITE050409		Click to Show/Hide the Full List
mod site	chr2:226796640-226796641:-		[6]
Sequence	CCAGCTATGGAAAGCTGTGGACAAACGGGGTAGGGGGCCAC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; fibroblasts; GM12878; H1299; Huh7; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513287
mod ID: M6ASITE050410		Click to Show/Hide the Full List
mod site	chr2:226796661-226796662:-		[6]
Sequence	GCAACGCCGTCCCTTCCGGGACCAGCTATGGAAAGCTGTGG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; fibroblasts; GM12878; H1299; Huh7; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513288
mod ID: M6ASITE050411		Click to Show/Hide the Full List
mod site	chr2:226796765-226796766:-		[6]
Sequence	ACGCCATCCCCAGAGAGTGGACCCCAATGGCTACATGATGA
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; H1299; Huh7; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513289
mod ID: M6ASITE050412		Click to Show/Hide the Full List
mod site	chr2:226796846-226796847:-		[6]
Sequence	TGGCCGAAAGGGCAGTGGAGACTATATGCCCATGAGCCCCA
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; H1299; Huh7; Jurkat; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513290
mod ID: M6ASITE050413		Click to Show/Hide the Full List
mod site	chr2:226796933-226796934:-		[6]
Sequence	GGGGGGGCACCACCGCCCAGACAGCTCCACCCTCCACACGG
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; Huh7; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513291
mod ID: M6ASITE050414		Click to Show/Hide the Full List
mod site	chr2:226797028-226797029:-		[6]
Sequence	AGTGGAGGCCGACTGCCGGGACACAGGCACTCCGCCTTCGT
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; H1A; hESCs; fibroblasts; H1299; Huh7; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513292
mod ID: M6ASITE050415		Click to Show/Hide the Full List
mod site	chr2:226797123-226797124:-		[6]
Sequence	CTACCATTACCCACCAGAAGACCCCGTCCCAGTCCTCAGTG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; hNPCs; hESCs; fibroblasts; H1299; Huh7; HEK293A-TOA; iSLK; MSC; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513293
mod ID: M6ASITE050416		Click to Show/Hide the Full List
mod site	chr2:226797150-226797151:-		[10]
Sequence	AGAGAACTCACTCGGCAGGCACATCCCCTACCATTACCCAC
Motif Score	2.830589286
Cell/Tissue List	kidney
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513294
mod ID: M6ASITE050417		Click to Show/Hide the Full List
mod site	chr2:226797165-226797166:-		[6]
Sequence	ATAATCGGTTCCGAAAGAGAACTCACTCGGCAGGCACATCC
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; hESCs; fibroblasts; H1299; Huh7; HEK293A-TOA; iSLK; MSC; TREX; endometrial
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513295
mod ID: M6ASITE050418		Click to Show/Hide the Full List
mod site	chr2:226797246-226797247:-		[6]
Sequence	GCCACCGCTGCACCCCAGGAACAGGCTTGGGCACGAGTCCA
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; HEK293T; fibroblasts; A549; Huh7; HEK293A-TOA; iSLK; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513296
mod ID: M6ASITE050419		Click to Show/Hide the Full List
mod site	chr2:226797678-226797679:-		[6]
Sequence	TGAGTCCCAGCACCAACAGAACCCACGCCCACCGGCATCGG
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; GSC-11; iSLK; MSC; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513297
mod ID: M6ASITE050420		Click to Show/Hide the Full List
mod site	chr2:226797984-226797985:-		[6]
Sequence	TGGCCCAGAACATGCACGAGACCATCCTGGAGGCCATGCGG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; U2OS; H1A; H1B; Huh7; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513298
mod ID: M6ASITE050421		Click to Show/Hide the Full List
mod site	chr2:226797995-226797996:-		[6]
Sequence	TGACTCTGTGGTGGCCCAGAACATGCACGAGACCATCCTGG
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; HEK293T; U2OS; H1A; H1B; Huh7; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513299
mod ID: M6ASITE050422		Click to Show/Hide the Full List
mod site	chr2:226798082-226798083:-		[6]
Sequence	GCGCTGTGGCCACTCGGAAAACTTCTTCTTCATCGAGGTGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513300
mod ID: M6ASITE050423		Click to Show/Hide the Full List
mod site	chr2:226798109-226798110:-		[6]
Sequence	CGTGGTGCTGCAGCTGATGAACATCAGGCGCTGTGGCCACT
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513301
mod ID: M6ASITE050424		Click to Show/Hide the Full List
mod site	chr2:226798145-226798146:-		[6]
Sequence	CATCAGCTTCGTGAAGCTGAACTCGGAGGCAGCGGCCGTGG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513302
mod ID: M6ASITE050425		Click to Show/Hide the Full List
mod site	chr2:226798167-226798168:-		[6]
Sequence	GCCTTTGCCTGACCAGCAAGACCATCAGCTTCGTGAAGCTG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513303
mod ID: M6ASITE050426		Click to Show/Hide the Full List
mod site	chr2:226798205-226798206:-		[6]
Sequence	GGGCCTGGGTCAGACAAAGAACCTGATTGGTATCTACCGCC
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; fibroblasts; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513304
mod ID: M6ASITE050427		Click to Show/Hide the Full List
mod site	chr2:226798212-226798213:-		[6]
Sequence	AGCCCAAGGGCCTGGGTCAGACAAAGAACCTGATTGGTATC
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; fibroblasts; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513305
mod ID: M6ASITE050428		Click to Show/Hide the Full List
mod site	chr2:226798267-226798268:-		[6]
Sequence	TACGGTGACGTGCCCCCAGGACCCGCATTCAAAGAGGTCTG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513306
mod ID: M6ASITE050429		Click to Show/Hide the Full List
mod site	chr2:226798295-226798296:-		[6]
Sequence	CCTTGGTGAGGCTGGGGAGGACTTGAGCTACGGTGACGTGC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513307
mod ID: M6ASITE050430		Click to Show/Hide the Full List
mod site	chr2:226798427-226798428:-		[6]
Sequence	GGACAGCGAGGCCGAGCAAGACAGCTGGTACCAGGCTCTCC
Motif Score	2.897386905
Cell/Tissue List	HeLa; HepG2; HEK293T; U2OS; A549; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513308
mod ID: M6ASITE050431		Click to Show/Hide the Full List
mod site	chr2:226798445-226798446:-		[6]
Sequence	GCACTTTGCCATCGCGGCGGACAGCGAGGCCGAGCAAGACA
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; U2OS; A549; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513309
mod ID: M6ASITE050432		Click to Show/Hide the Full List
mod site	chr2:226798499-226798500:-		[6]
Sequence	CAAGCGGGCTGACTCCAAGAACAAGCACCTGGTGGCTCTCT
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; U2OS; A549; Huh7; peripheral-blood; HEK293A-TOA; iSLK; MSC; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513310
mod ID: M6ASITE050433		Click to Show/Hide the Full List
mod site	chr2:226798675-226798676:-		[6]
Sequence	AAGGTGGGCTACCTGCGCAAACCCAAGAGCATGCACAAACG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; U2OS; iSLK; MSC; endometrial
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513311
mod ID: M6ASITE050434		Click to Show/Hide the Full List
mod site	chr2:226798948-226798949:-		[6]
Sequence	CGGGCGTGAAGCGCCCGAAAACTCCGGTCGGGCTCTCTCCT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; GM12878; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513312
mod ID: M6ASITE050435		Click to Show/Hide the Full List
mod site	chr2:226799023-226799024:-		[6]
Sequence	GCGGCGGCGGCTGAGAGGAGACTTGGCTCTCGGAGGATCGG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; Jurkat; CD4T; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513313
mod ID: M6ASITE050436		Click to Show/Hide the Full List
mod site	chr2:226799089-226799090:-		[6]
Sequence	CTGTCGCCTCCCTGTGCCGGACTCCAGCCGGGGCGACGAGA
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; Jurkat; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513314
mod ID: M6ASITE050437		Click to Show/Hide the Full List
mod site	chr2:226799117-226799118:-		[6]
Sequence	CCTGGAGGGGCACCGCAGGGACCCCCGACTGTCGCCTCCCT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; Jurkat; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513315
mod ID: M6ASITE050438		Click to Show/Hide the Full List
mod site	chr2:226799170-226799171:-		[6]
Sequence	ATCGCTGCTTCCAGAGGGGAACTCAGGAGGGAAGGCGCGCG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; Huh7; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513316
mod ID: M6ASITE050439		Click to Show/Hide the Full List
mod site	chr2:226799240-226799241:-		[6]
Sequence	GAACCCCGTGCAACGTTGGGACTTGGCAACCCGCCTCCCCC
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; Huh7; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513317
mod ID: M6ASITE050440		Click to Show/Hide the Full List
mod site	chr2:226799258-226799259:-		[6]
Sequence	GAGGCGAAGGAGGAGGGAGAACCCCGTGCAACGTTGGGACT
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; Huh7; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513318
mod ID: M6ASITE050441		Click to Show/Hide the Full List
mod site	chr2:226799590-226799591:-		[6]
Sequence	CTTCCCCGAACCCTTCCCAAACCTCCCCCATCCCCTCTCGC
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; A549; H1B; H1A; peripheral-blood; GSC-11; HEK293T; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513319
mod ID: M6ASITE050442		Click to Show/Hide the Full List
mod site	chr2:226799601-226799602:-		[6]
Sequence	GGAACAGGCGTCTTCCCCGAACCCTTCCCAAACCTCCCCCA
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; A549; H1B; H1A; peripheral-blood; GSC-11; HEK293T; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513320
mod ID: M6ASITE050443		Click to Show/Hide the Full List
mod site	chr2:226799618-226799619:-		[6]
Sequence	GCGGCAGCGCCTCCCGAGGAACAGGCGTCTTCCCCGAACCC
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; A549; H1B; H1A; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000305123.5
External Link	RMBase: m6A_site_513321

Ref 1	YTHDF2 inhibit the tumorigenicity of endometrial cancer via downregulating the expression of IRS1 methylated with m(6)A. J Cancer. 2021 May 5;12(13):3809-3818. doi: 10.7150/jca.54527. eCollection 2021.
Ref 2	Breast cancer resistance protein (BCRP/ABCG2) transports fluoroquinolone antibiotics and affects their oral availability, pharmacokinetics, and milk secretion. Drug Metab Dispos. 2006 Apr;34(4):690-5. doi: 10.1124/dmd.105.008219. Epub 2006 Jan 24.
Ref 3	RADAR: a rigorously annotated database of A-to-I RNA editing. Nucleic Acids Res. 2014 Jan;42(Database issue):D109-13. doi: 10.1093/nar/gkt996. Epub 2013 Oct 25.
Ref 4	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 5	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 6	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 7	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 8	A majority of m6A residues are in the last exons, allowing the potential for 3' UTR regulation. Genes Dev. 2015 Oct 1;29(19):2037-53. doi: 10.1101/gad.269415.115. Epub 2015 Sep 24.
Ref 9	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10;8(1):284-96. doi: 10.1016/j.celrep.2014.05.048. Epub 2014 Jun 26.
Ref 10	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

Visitor Map