m6A Target Gene Information
General Information of the m6A Target Gene (ID: M6ATAR00474)
| Target Name | Protein AATF (AATF/CHE1) | ||||
|---|---|---|---|---|---|
| Synonyms |
Apoptosis-antagonizing transcription factor; Rb-binding protein Che-1; CHE1; DED; HSPC277
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| Gene Name | AATF | ||||
| Chromosomal Location | 17q12 | ||||
| Family | AATF family. {ECO:0000305}. | ||||
| Function |
May function as a general inhibitor of the histone deacetylase HDAC1. Binding to the pocket region of RB1 may displace HDAC1 from RB1/E2F complexes, leading to activation of E2F target genes and cell cycle progression. Conversely, displacement of HDAC1 from SP1 bound to the CDKN1A promoter leads to increased expression of this CDK inhibitor and blocks cell cycle progression. Also antagonizes PAWR mediated induction of aberrant amyloid peptide production in Alzheimer disease (presenile and senile dementia), although the molecular basis for this phenomenon has not been described to date. {ECO:0000269|PubMed:12450794, ECO:0000269|PubMed:12847090, ECO:0000269|PubMed:14627703, ECO:0000269|PubMed:15207272}.
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Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
AATF
can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
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Methyltransferase-like 3 (METTL3) [WRITER]
| Representative RNA-seq result indicating the expression of this target gene regulated by METTL3 | ||
| Cell Line | Liver | Mus musculus |
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Treatment: Mettl3 knockout liver
Control: Wild type liver cells
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GSE198513 | |
| Regulation |
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logFC: -6.23E-01 p-value: 2.02E-10 |
| More Results | Click to View More RNA-seq Results | |
| In total 1 item(s) under this regulator | ||||
| Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene | [1] | |||
| Response Summary | METTL3 promotes adriamycin resistance in MCF-7 breast cancer cells by accelerating pri-microRNA-221-3p maturation in a m6A-dependent manner. METTL3 knockdown was shown to reduce the expression of miR-221-3p by reducing pri-miR-221-3p m6A mRNA methylation, reducing the expression of MDR1 and BCRP, and inducing apoptosis. Identified the METTL3/miR-221-3p/HIPK2/Protein AATF (AATF/CHE1) axis as a novel signaling event that will be responsible for resistance of BC cells to ADR. | |||
| Target Regulation | Up regulation | |||
| Responsed Disease | Breast cancer | ICD-11: 2C60 | ||
| Responsed Drug | Doxil | Approved | ||
| Cell Process | Cell growth and death | |||
| Cell apoptosis | ||||
| In-vitro Model | ADR-resistant MCF-7 (MCF-7/ADR) cells (Human breast cancer doxorubicin-resistant cell line) | |||
| MCF-7 | Invasive breast carcinoma | Homo sapiens | CVCL_0031 | |
| MCF-10A | Normal | Homo sapiens | CVCL_0598 | |
| In-vivo Model | Cell suspensions (2 × 106 cells/mL) made with MCF-7/ADR cells stably expressing METTL3 and/or miR-221-3p inhibitor were subcutaneously implanted into each mouse. One week later, xenografted mice were injected with 0.1 mL ADR (25 mg/kg, intraperitoneal injection) twice a week. | |||
Breast cancer [ICD-11: 2C60]
| In total 1 item(s) under this disease | ||||
| Experiment 1 Reporting the m6A-centered Disease Response | [1] | |||
| Response Summary | METTL3 promotes adriamycin resistance in MCF-7 breast cancer cells by accelerating pri-microRNA-221-3p maturation in a m6A-dependent manner. METTL3 knockdown was shown to reduce the expression of miR-221-3p by reducing pri-miR-221-3p m6A mRNA methylation, reducing the expression of MDR1 and BCRP, and inducing apoptosis. Identified the METTL3/miR-221-3p/HIPK2/Protein AATF (AATF/CHE1) axis as a novel signaling event that will be responsible for resistance of BC cells to ADR. | |||
| Responsed Disease | Breast cancer [ICD-11: 2C60] | |||
| Target Regulator | Methyltransferase-like 3 (METTL3) | WRITER | ||
| Target Regulation | Up regulation | |||
| Responsed Drug | Doxil | Approved | ||
| Cell Process | Cell growth and death | |||
| Cell apoptosis | ||||
| In-vitro Model | ADR-resistant MCF-7 (MCF-7/ADR) cells (Human breast cancer doxorubicin-resistant cell line) | |||
| MCF-7 | Invasive breast carcinoma | Homo sapiens | CVCL_0031 | |
| MCF-10A | Normal | Homo sapiens | CVCL_0598 | |
| In-vivo Model | Cell suspensions (2 × 106 cells/mL) made with MCF-7/ADR cells stably expressing METTL3 and/or miR-221-3p inhibitor were subcutaneously implanted into each mouse. One week later, xenografted mice were injected with 0.1 mL ADR (25 mg/kg, intraperitoneal injection) twice a week. | |||
Doxil
[Approved]
| In total 1 item(s) under this drug | ||||
| Experiment 1 Reporting the m6A-centered Drug Response | [1] | |||
| Response Summary | METTL3 promotes adriamycin resistance in MCF-7 breast cancer cells by accelerating pri-microRNA-221-3p maturation in a m6A-dependent manner. METTL3 knockdown was shown to reduce the expression of miR-221-3p by reducing pri-miR-221-3p m6A mRNA methylation, reducing the expression of MDR1 and BCRP, and inducing apoptosis. Identified the METTL3/miR-221-3p/HIPK2/Protein AATF (AATF/CHE1) axis as a novel signaling event that will be responsible for resistance of BC cells to ADR. | |||
| Target Regulator | Methyltransferase-like 3 (METTL3) | WRITER | ||
| Target Regulation | Up regulation | |||
| Responsed Disease | Breast cancer | ICD-11: 2C60 | ||
| Cell Process | Cell growth and death | |||
| Cell apoptosis | ||||
| In-vitro Model | ADR-resistant MCF-7 (MCF-7/ADR) cells (Human breast cancer doxorubicin-resistant cell line) | |||
| MCF-7 | Invasive breast carcinoma | Homo sapiens | CVCL_0031 | |
| MCF-10A | Normal | Homo sapiens | CVCL_0598 | |
| In-vivo Model | Cell suspensions (2 × 106 cells/mL) made with MCF-7/ADR cells stably expressing METTL3 and/or miR-221-3p inhibitor were subcutaneously implanted into each mouse. One week later, xenografted mice were injected with 0.1 mL ADR (25 mg/kg, intraperitoneal injection) twice a week. | |||
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00474)
| In total 30 m6A sequence/site(s) in this target gene | |||
| mod ID: A2ISITE007894 | Click to Show/Hide the Full List | ||
| mod site | chr17:36968674-36968675:+ | [2] | |
| Sequence | TCTGTCACCTAGACCGGAGTACAGTGGTGTGATCATAGCTC | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: RNA-editing_site_56946 | ||
| mod ID: A2ISITE007895 | Click to Show/Hide the Full List | ||
| mod site | chr17:36970184-36970185:+ | [2] | |
| Sequence | ATGCATGTTTAACTTCGGAAACTGCCAAGCTATTTTCCAAA | ||
| Transcript ID List | ENST00000613840.1; ENST00000619387.5 | ||
| External Link | RMBase: RNA-editing_site_56947 | ||
| mod ID: A2ISITE007896 | Click to Show/Hide the Full List | ||
| mod site | chr17:36970195-36970196:+ | [2] | |
| Sequence | ACTTCGGAAACTGCCAAGCTATTTTCCAAAGTGGTTATACC | ||
| Transcript ID List | ENST00000613840.1; ENST00000619387.5 | ||
| External Link | RMBase: RNA-editing_site_56948 | ||
| mod ID: A2ISITE007897 | Click to Show/Hide the Full List | ||
| mod site | chr17:36970211-36970212:+ | [2] | |
| Sequence | AGCTATTTTCCAAAGTGGTTATACCATTTTGCAGTCCCACC | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: RNA-editing_site_56949 | ||
| mod ID: A2ISITE007898 | Click to Show/Hide the Full List | ||
| mod site | chr17:36970216-36970217:+ | [2] | |
| Sequence | TTTTCCAAAGTGGTTATACCATTTTGCAGTCCCACCAGCAG | ||
| Transcript ID List | ENST00000613840.1; ENST00000619387.5 | ||
| External Link | RMBase: RNA-editing_site_56950 | ||
| mod ID: A2ISITE007899 | Click to Show/Hide the Full List | ||
| mod site | chr17:36971437-36971438:+ | [2] | |
| Sequence | CCAAGTGCTGGGAAGAATGTAGAGCAACTGGAGCTTTCATA | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1; rmsk_4682631 | ||
| External Link | RMBase: RNA-editing_site_56951 | ||
| mod ID: A2ISITE007900 | Click to Show/Hide the Full List | ||
| mod site | chr17:36971481-36971482:+ | [2] | |
| Sequence | TGCTGATGGGAATGCAAAATAGTACAGCCACTTTGGAAAAA | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1; rmsk_4682631 | ||
| External Link | RMBase: RNA-editing_site_56952 | ||
| mod ID: A2ISITE007901 | Click to Show/Hide the Full List | ||
| mod site | chr17:36971528-36971529:+ | [3] | |
| Sequence | GGCAGTTTTTAAATAAAGCTAAACATATATTCATCATACGA | ||
| Transcript ID List | ENST00000619387.5; rmsk_4682631; ENST00000613840.1 | ||
| External Link | RMBase: RNA-editing_site_56953 | ||
| mod ID: A2ISITE007902 | Click to Show/Hide the Full List | ||
| mod site | chr17:36971545-36971546:+ | [3] | |
| Sequence | GCTAAACATATATTCATCATACGAGCCTGATCCAGTAGTCT | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1; rmsk_4682631 | ||
| External Link | RMBase: RNA-editing_site_56954 | ||
| mod ID: A2ISITE007903 | Click to Show/Hide the Full List | ||
| mod site | chr17:36971649-36971650:+ | [2] | |
| Sequence | CGTTCATAGCAGCATTATTTATAATCACCAAAAACTGGAAA | ||
| Transcript ID List | rmsk_4682631; ENST00000613840.1; ENST00000619387.5 | ||
| External Link | RMBase: RNA-editing_site_56955 | ||
| mod ID: A2ISITE007904 | Click to Show/Hide the Full List | ||
| mod site | chr17:36971764-36971765:+ | [2] | |
| Sequence | AAAAACGTGGATGAACCTCAAGGGTATTATACTAAGTGAAA | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1; rmsk_4682631 | ||
| External Link | RMBase: RNA-editing_site_56956 | ||
| mod ID: A2ISITE007905 | Click to Show/Hide the Full List | ||
| mod site | chr17:36971774-36971775:+ | [2] | |
| Sequence | ATGAACCTCAAGGGTATTATACTAAGTGAAATATGCCAGCC | ||
| Transcript ID List | rmsk_4682631; ENST00000613840.1; ENST00000619387.5 | ||
| External Link | RMBase: RNA-editing_site_56957 | ||
| mod ID: A2ISITE007906 | Click to Show/Hide the Full List | ||
| mod site | chr17:36971777-36971778:+ | [2] | |
| Sequence | AACCTCAAGGGTATTATACTAAGTGAAATATGCCAGCCTCA | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1; rmsk_4682631 | ||
| External Link | RMBase: RNA-editing_site_56958 | ||
| mod ID: A2ISITE007907 | Click to Show/Hide the Full List | ||
| mod site | chr17:36971873-36971874:+ | [2] | |
| Sequence | ATTGGGACAGATCAGTGGCTACCATGGATTAGGAATGGGAG | ||
| Transcript ID List | rmsk_4682631; ENST00000613840.1; ENST00000619387.5 | ||
| External Link | RMBase: RNA-editing_site_56959 | ||
| mod ID: A2ISITE007908 | Click to Show/Hide the Full List | ||
| mod site | chr17:36996383-36996384:+ | [2] | |
| Sequence | GTCGAAGCTACGGTGAGCCAAGATCGCATCACTACACTCCA | ||
| Transcript ID List | ENST00000610798.4; rmsk_4682675; ENST00000616434.1; ENST00000619387.5 | ||
| External Link | RMBase: RNA-editing_site_56960 | ||
| mod ID: A2ISITE007909 | Click to Show/Hide the Full List | ||
| mod site | chr17:37010276-37010277:+ | [2] | |
| Sequence | ATCCTGGCTAACATGGTGAAACCCTGTCCCTACTAAAAATA | ||
| Transcript ID List | ENST00000610798.4; ENST00000619387.5; rmsk_4682717; ENST00000616434.1 | ||
| External Link | RMBase: RNA-editing_site_56961 | ||
| mod ID: A2ISITE007910 | Click to Show/Hide the Full List | ||
| mod site | chr17:37011227-37011228:+ | [2] | |
| Sequence | TAAAAATTTATACAAAAATTAGCCCGGCGTGGTGGTGCACG | ||
| Transcript ID List | rmsk_4682721; ENST00000619387.5; ENST00000616434.1; ENST00000610798.4 | ||
| External Link | RMBase: RNA-editing_site_56962 | ||
| mod ID: A2ISITE007911 | Click to Show/Hide the Full List | ||
| mod site | chr17:37023499-37023500:+ | [2] | |
| Sequence | AGTAAAATCTTATTCTTTTTAAACAGAGTTTAAAAAGAGGC | ||
| Transcript ID List | ENST00000616392.1; ENST00000616434.1; ENST00000619387.5 | ||
| External Link | RMBase: RNA-editing_site_56963 | ||
| mod ID: A2ISITE007912 | Click to Show/Hide the Full List | ||
| mod site | chr17:37023895-37023896:+ | [2] | |
| Sequence | ATGCTCAAGTTCCTTATATAAAGTGGCATAGTATTTGCATA | ||
| Transcript ID List | ENST00000619387.5; ENST00000616392.1; ENST00000616434.1 | ||
| External Link | RMBase: RNA-editing_site_56964 | ||
| mod ID: A2ISITE007913 | Click to Show/Hide the Full List | ||
| mod site | chr17:37023915-37023916:+ | [2] | |
| Sequence | AAGTGGCATAGTATTTGCATATAACCTACACACATCCTCCC | ||
| Transcript ID List | ENST00000616434.1; ENST00000619387.5; ENST00000616392.1 | ||
| External Link | RMBase: RNA-editing_site_56965 | ||
| mod ID: A2ISITE007914 | Click to Show/Hide the Full List | ||
| mod site | chr17:37023981-37023982:+ | [2] | |
| Sequence | CTTATAATACCTAGTTCAATATGAACGCCATGTAAATAATT | ||
| Transcript ID List | ENST00000619387.5; ENST00000616392.1; ENST00000616434.1 | ||
| External Link | RMBase: RNA-editing_site_56966 | ||
| mod ID: A2ISITE007915 | Click to Show/Hide the Full List | ||
| mod site | chr17:37028678-37028679:+ | [4] | |
| Sequence | TCCTGTAGTTCCAGCTACTCAGGAGGCTGAGGTGAGAGGAT | ||
| Transcript ID List | ENST00000619387.5; ENST00000616392.1; rmsk_4682765; ENST00000616434.1 | ||
| External Link | RMBase: RNA-editing_site_56967 | ||
| mod ID: A2ISITE007916 | Click to Show/Hide the Full List | ||
| mod site | chr17:37031241-37031242:+ | [2] | |
| Sequence | GTCATTATTCCCTGAACAATACATTGTACAACTATTTACGT | ||
| Transcript ID List | ENST00000619387.5; ENST00000616434.1; ENST00000616392.1; rmsk_4682774 | ||
| External Link | RMBase: RNA-editing_site_56968 | ||
| mod ID: A2ISITE007917 | Click to Show/Hide the Full List | ||
| mod site | chr17:37031271-37031272:+ | [2] | |
| Sequence | ACTATTTACGTAGCATTTACATTGCATTAAGTATTTTAAGT | ||
| Transcript ID List | rmsk_4682774; ENST00000616434.1; ENST00000616392.1; ENST00000619387.5 | ||
| External Link | RMBase: RNA-editing_site_56969 | ||
| mod ID: A2ISITE007918 | Click to Show/Hide the Full List | ||
| mod site | chr17:37031279-37031280:+ | [2] | |
| Sequence | CGTAGCATTTACATTGCATTAAGTATTTTAAGTAATCTAGA | ||
| Transcript ID List | rmsk_4682774; ENST00000616392.1; ENST00000619387.5; ENST00000616434.1 | ||
| External Link | RMBase: RNA-editing_site_56970 | ||
| mod ID: A2ISITE007919 | Click to Show/Hide the Full List | ||
| mod site | chr17:37031280-37031281:+ | [2] | |
| Sequence | GTAGCATTTACATTGCATTAAGTATTTTAAGTAATCTAGAG | ||
| Transcript ID List | rmsk_4682774; ENST00000616392.1; ENST00000619387.5; ENST00000616434.1 | ||
| External Link | RMBase: RNA-editing_site_56971 | ||
| mod ID: A2ISITE007920 | Click to Show/Hide the Full List | ||
| mod site | chr17:37031358-37031359:+ | [2] | |
| Sequence | TGCAAATACTATGCCATTTTATATAAGGAACTTGAGCATCC | ||
| Transcript ID List | rmsk_4682774; ENST00000616392.1; ENST00000616434.1; ENST00000619387.5 | ||
| External Link | RMBase: RNA-editing_site_56972 | ||
| mod ID: A2ISITE007921 | Click to Show/Hide the Full List | ||
| mod site | chr17:37031362-37031363:+ | [2] | |
| Sequence | AATACTATGCCATTTTATATAAGGAACTTGAGCATCCGTGG | ||
| Transcript ID List | ENST00000619387.5; ENST00000616392.1; ENST00000616434.1; rmsk_4682774 | ||
| External Link | RMBase: RNA-editing_site_56973 | ||
| mod ID: A2ISITE007922 | Click to Show/Hide the Full List | ||
| mod site | chr17:37031363-37031364:+ | [2] | |
| Sequence | ATACTATGCCATTTTATATAAGGAACTTGAGCATCCGTGGA | ||
| Transcript ID List | rmsk_4682774; ENST00000616434.1; ENST00000619387.5; ENST00000616392.1 | ||
| External Link | RMBase: RNA-editing_site_56974 | ||
| mod ID: A2ISITE007923 | Click to Show/Hide the Full List | ||
| mod site | chr17:37049423-37049424:+ | [2] | |
| Sequence | CATCCTGGCTAACACAGTGAAACCCTGTGTGTACTAAAAAT | ||
| Transcript ID List | ENST00000617141.1; rmsk_4682802; ENST00000616392.1; ENST00000619387.5; ENST00000616434.1 | ||
| External Link | RMBase: RNA-editing_site_56975 | ||
5-methylcytidine (m5C)
| In total 1 m6A sequence/site(s) in this target gene | |||
| mod ID: M5CSITE001091 | Click to Show/Hide the Full List | ||
| mod site | chr17:36989363-36989364:+ | [5] | |
| Sequence | TCTATCGAGTTCTTGGCAAACCTGAGCCAGCAGCTCAGCCT | ||
| Cell/Tissue List | frontalcortex; lung; testis; HeLa; T24 | ||
| Seq Type List | Bisulfite-seq; m5C-RIP-seq | ||
| Transcript ID List | ENST00000619387.5; ENST00000610798.4 | ||
| External Link | RMBase: m5C_site_18590 | ||
N6-methyladenosine (m6A)
| In total 27 m6A sequence/site(s) in this target gene | |||
| mod ID: M6ASITE031978 | Click to Show/Hide the Full List | ||
| mod site | chr17:36949082-36949083:+ | [6] | |
| Sequence | GGGGCCGGGGGTTGGGCCGCACATTTACGTGCGCGAAGCGG | ||
| Motif Score | 2.830589286 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: m6A_site_359453 | ||
| mod ID: M6ASITE031979 | Click to Show/Hide the Full List | ||
| mod site | chr17:36950234-36950235:+ | [7] | |
| Sequence | CACTGCTGCCAGGGTGATTGACAGGTTTGATGAAGGGGAAG | ||
| Motif Score | 2.859755952 | ||
| Cell/Tissue List | HEK293T | ||
| Seq Type List | DART-seq | ||
| Transcript ID List | ENST00000613840.1; ENST00000619387.5 | ||
| External Link | RMBase: m6A_site_359454 | ||
| mod ID: M6ASITE031980 | Click to Show/Hide the Full List | ||
| mod site | chr17:36950318-36950319:+ | [6] | |
| Sequence | GGCATCAGCCTCCCTCTTGGACACGGACAAAAGGTATTGCG | ||
| Motif Score | 3.643047619 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: m6A_site_359455 | ||
| mod ID: M6ASITE031981 | Click to Show/Hide the Full List | ||
| mod site | chr17:36950324-36950325:+ | [6] | |
| Sequence | AGCCTCCCTCTTGGACACGGACAAAAGGTATTGCGGCAAAA | ||
| Motif Score | 3.643047619 | ||
| Cell/Tissue List | hESC-HEK293T; AML | ||
| Seq Type List | MAZTER-seq; miCLIP | ||
| Transcript ID List | ENST00000613840.1; ENST00000619387.5 | ||
| External Link | RMBase: m6A_site_359456 | ||
| mod ID: M6ASITE031982 | Click to Show/Hide the Full List | ||
| mod site | chr17:36952982-36952983:+ | [6] | |
| Sequence | GACCTGGGTGCTGCTGAGGAACAGGAGTGTGGTGATCACAG | ||
| Motif Score | 2.951386905 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: m6A_site_359457 | ||
| mod ID: M6ASITE031983 | Click to Show/Hide the Full List | ||
| mod site | chr17:36953037-36953038:+ | [6] | |
| Sequence | GCAGAAGCCACTCTGCAAAAACACCGGGCTTCAGTGTCCAG | ||
| Motif Score | 2.20572619 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: m6A_site_359458 | ||
| mod ID: M6ASITE031984 | Click to Show/Hide the Full List | ||
| mod site | chr17:36953068-36953069:+ | [8] | |
| Sequence | CAGTGTCCAGAGTATCAGTGACTTTGAGAAATTTACCAAGG | ||
| Motif Score | 3.28175 | ||
| Cell/Tissue List | A549 | ||
| Seq Type List | m6A-CLIP/IP | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: m6A_site_359459 | ||
| mod ID: M6ASITE031985 | Click to Show/Hide the Full List | ||
| mod site | chr17:36953206-36953207:+ | [9] | |
| Sequence | AGACAGGGCTGGAGATAGAAACAGTGAGGATGATGGTGTGG | ||
| Motif Score | 2.20572619 | ||
| Cell/Tissue List | kidney | ||
| Seq Type List | m6A-REF-seq | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: m6A_site_359460 | ||
| mod ID: M6ASITE031986 | Click to Show/Hide the Full List | ||
| mod site | chr17:36953806-36953807:+ | [6] | |
| Sequence | TTGGAAGGAAGGATCAAACTACAAAAAGCTCTGTTGACCAC | ||
| Motif Score | 2.078666667 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: m6A_site_359461 | ||
| mod ID: M6ASITE031987 | Click to Show/Hide the Full List | ||
| mod site | chr17:36953868-36953869:+ | [6] | |
| Sequence | TGTTTTCCCATTGTTCAAGGACAAAGGTGGCCCAGAATTTT | ||
| Motif Score | 3.643047619 | ||
| Cell/Tissue List | hESC-HEK293T; AML | ||
| Seq Type List | MAZTER-seq; miCLIP | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: m6A_site_359462 | ||
| mod ID: M6ASITE031988 | Click to Show/Hide the Full List | ||
| mod site | chr17:36986619-36986620:+ | [6] | |
| Sequence | TGTCCTTTATTTCCCAGGTCACAAGGCACTTAAAGCATTGT | ||
| Motif Score | 2.047297619 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: m6A_site_359463 | ||
| mod ID: M6ASITE031989 | Click to Show/Hide the Full List | ||
| mod site | chr17:36986688-36986689:+ | [6] | |
| Sequence | GTTGCTTTTCCAGTACCCAGACACTAGATATCTAGTAGATG | ||
| Motif Score | 2.897386905 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: m6A_site_359464 | ||
| mod ID: M6ASITE031990 | Click to Show/Hide the Full List | ||
| mod site | chr17:36986711-36986712:+ | [6] | |
| Sequence | CTAGATATCTAGTAGATGGGACAAAGCCCAATGCGGGAAGG | ||
| Motif Score | 3.643047619 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: m6A_site_359465 | ||
| mod ID: M6ASITE031991 | Click to Show/Hide the Full List | ||
| mod site | chr17:36988666-36988667:+ | [6] | |
| Sequence | TTACAGTCTACAGGAACCGCACACTTCAGAAATGGCACGAT | ||
| Motif Score | 2.830589286 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000610798.4; ENST00000619387.5; ENST00000613840.1 | ||
| External Link | RMBase: m6A_site_359466 | ||
| mod ID: M6ASITE031992 | Click to Show/Hide the Full List | ||
| mod site | chr17:36989301-36989302:+ | [6] | |
| Sequence | GATCGACCATATTCTGATGGACAAAGAGAGATTACTTCGAA | ||
| Motif Score | 3.643047619 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000619387.5; ENST00000610798.4 | ||
| External Link | RMBase: m6A_site_359467 | ||
| mod ID: M6ASITE031993 | Click to Show/Hide the Full List | ||
| mod site | chr17:37020971-37020972:+ | [6] | |
| Sequence | GAAGTTACGAAGCAAAATCCACAAAAAAGTAGATAGGAAAG | ||
| Motif Score | 2.053113095 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000610798.4; ENST00000619387.5; ENST00000616392.1; ENST00000616434.1 | ||
| External Link | RMBase: m6A_site_359468 | ||
| mod ID: M6ASITE031994 | Click to Show/Hide the Full List | ||
| mod site | chr17:37031665-37031666:+ | [6] | |
| Sequence | TGGCACCTATTGACCATACTACAATGAATGATGATGCCAGG | ||
| Motif Score | 2.078666667 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000617141.1; ENST00000616434.1; ENST00000616392.1; ENST00000619387.5 | ||
| External Link | RMBase: m6A_site_359469 | ||
| mod ID: M6ASITE031995 | Click to Show/Hide the Full List | ||
| mod site | chr17:37056663-37056664:+ | [6] | |
| Sequence | GACGAAGGCCACGGGGATTGACATCGCCCACCTCCGACACC | ||
| Motif Score | 2.859755952 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000622432.1; ENST00000617141.1; ENST00000616434.1; ENST00000616392.1; ENST00000615319.1; ENST00000616062.1; ENST00000619387.5 | ||
| External Link | RMBase: m6A_site_359470 | ||
| mod ID: M6ASITE031996 | Click to Show/Hide the Full List | ||
| mod site | chr17:37056679-37056680:+ | [6] | |
| Sequence | ATTGACATCGCCCACCTCCGACACCCAGTGGGCGCCTTGGC | ||
| Motif Score | 2.865571429 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000616434.1; ENST00000616062.1; ENST00000615319.1; ENST00000622432.1; ENST00000619387.5; ENST00000616392.1; ENST00000617141.1 | ||
| External Link | RMBase: m6A_site_359471 | ||
| mod ID: M6ASITE031997 | Click to Show/Hide the Full List | ||
| mod site | chr17:37056802-37056803:+ | [6] | |
| Sequence | GTTCCGAACCTGTGCCTAATACACGCAAGGGCGCTGTCCCG | ||
| Motif Score | 2.110482143 | ||
| Cell/Tissue List | hESC-HEK293T | ||
| Seq Type List | MAZTER-seq | ||
| Transcript ID List | ENST00000622432.1; ENST00000617141.1; ENST00000616434.1; ENST00000616062.1; ENST00000615319.1; ENST00000616392.1; ENST00000619387.5 | ||
| External Link | RMBase: m6A_site_359472 | ||
| mod ID: M6ASITE094648 | Click to Show/Hide the Full List | ||
| mod site | KI270857.1:1186751-1186752:+ | [10] | |
| Sequence | ATGAAGACCATTGGGAGCAGACTCTGCCAGGATCGTCTGGT | ||
| Motif Score | 3.319380952 | ||
| Cell/Tissue List | HeLa | ||
| Seq Type List | m6A-seq | ||
| Transcript ID List | ENST00000620004.2; ENST00000632039.1 | ||
| External Link | RMBase: m6A_site_881250 | ||
| mod ID: M6ASITE094649 | Click to Show/Hide the Full List | ||
| mod site | KI270857.1:1189299-1189300:+ | [10] | |
| Sequence | GGAGATGAAGATTCAGAGGGACTGGGTCTGGAGGAATATGA | ||
| Motif Score | 4.065041667 | ||
| Cell/Tissue List | HeLa; HEK293A-TOA | ||
| Seq Type List | m6A-seq | ||
| Transcript ID List | ENST00000620004.2; ENST00000632039.1 | ||
| External Link | RMBase: m6A_site_881251 | ||
| mod ID: M6ASITE094650 | Click to Show/Hide the Full List | ||
| mod site | KI270857.1:1189347-1189348:+ | [10] | |
| Sequence | GACCTGGGTGCTGCTGAGGAACAGGAGTGTGGTGATCACAG | ||
| Motif Score | 2.951386905 | ||
| Cell/Tissue List | HeLa | ||
| Seq Type List | m6A-seq | ||
| Transcript ID List | ENST00000620004.2; ENST00000632039.1 | ||
| External Link | RMBase: m6A_site_881252 | ||
| mod ID: M6ASITE094651 | Click to Show/Hide the Full List | ||
| mod site | KI270857.1:1189402-1189403:+ | [10] | |
| Sequence | GCAGAAGCCACTCTGCAAAAACACCGGGCTTCAGTGTCCAG | ||
| Motif Score | 2.20572619 | ||
| Cell/Tissue List | HeLa | ||
| Seq Type List | m6A-seq | ||
| Transcript ID List | ENST00000620004.2; ENST00000632039.1 | ||
| External Link | RMBase: m6A_site_881253 | ||
| mod ID: M6ASITE094652 | Click to Show/Hide the Full List | ||
| mod site | KI270857.1:1189529-1189530:+ | [10] | |
| Sequence | AGAAGGGGATGACGCGGAAGACTCCCAAGGCGAGAGTGAGG | ||
| Motif Score | 3.319380952 | ||
| Cell/Tissue List | HeLa | ||
| Seq Type List | m6A-seq | ||
| Transcript ID List | ENST00000632039.1; ENST00000620004.2; rmsk_5542434 | ||
| External Link | RMBase: m6A_site_881254 | ||
| mod ID: M6ASITE094653 | Click to Show/Hide the Full List | ||
| mod site | KI270857.1:1189553-1189554:+ | [10] | |
| Sequence | CCAAGGCGAGAGTGAGGAAGACAGGGCTGGAGATAGAAACA | ||
| Motif Score | 2.897386905 | ||
| Cell/Tissue List | HeLa | ||
| Seq Type List | m6A-seq | ||
| Transcript ID List | ENST00000620004.2; ENST00000632039.1 | ||
| External Link | RMBase: m6A_site_881255 | ||
| mod ID: M6ASITE094654 | Click to Show/Hide the Full List | ||
| mod site | KI270857.1:1189571-1189572:+ | [10] | |
| Sequence | AGACAGGGCTGGAGATAGAAACAGTGAGGATGATGGTGTGG | ||
| Motif Score | 2.20572619 | ||
| Cell/Tissue List | HeLa | ||
| Seq Type List | m6A-seq | ||
| Transcript ID List | ENST00000632039.1; ENST00000620004.2 | ||
| External Link | RMBase: m6A_site_881256 | ||
References