m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00268)
Target Name Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B)
Synonyms
GSK-3 beta; Serine/threonine-protein kinase GSK3B
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Gene Name GSK3B
Chromosomal Location 3q13.33
Family protein kinase superfamily; CMGC Ser/Thr protein kinase family; GSK-3 subfamily
Function
Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), EIF2B, CTNNB1/beta-catenin, APC, AXIN1, DPYSL2/CRMP2, JUN, NFATC1/NFATC, MAPT/TAU and MACF1. Requires primed phosphorylation of the majority of its substrates. In skeletal muscle, contributes to insulin regulation of glycogen synthesis by phosphorylating and inhibiting GYS1 activity and hence glycogen synthesis. May also mediate the development of insulin resistance by regulating activation of transcription factors. Regulates protein synthesis by controlling the activity of initiation factor 2B (EIF2BE/EIF2B5) in the same manner as glycogen synthase. In Wnt signaling, GSK3B forms a multimeric complex with APC, AXIN1 and CTNNB1/beta-catenin and phosphorylates the N-terminus of CTNNB1 leading to its degradation mediated by ubiquitin/proteasomes. Phosphorylates JUN at sites proximal to its DNA-binding domain, thereby reducing its affinity for DNA. Phosphorylates NFATC1/NFATC on conserved serine residues promoting NFATC1/NFATC nuclear export, shutting off NFATC1/NFATC gene regulation, and thereby opposing the action of calcineurin. Phosphorylates MAPT/TAU on 'Thr-548', decreasing significantly MAPT/TAU ability to bind and stabilize microtubules. MAPT/TAU is the principal component of neurofibrillary tangles in Alzheimer disease. Plays an important role in ERBB2-dependent stabilization of microtubules at the cell cortex. Phosphorylates MACF1, inhibiting its binding to microtubules which is critical for its role in bulge stem cell migration and skin wound repair (By similarity). Probably regulates NF-kappa-B (NFKB1) at the transcriptional level and is required for the NF-kappa-B-mediated anti-apoptotic response to TNF-alpha (TNF/TNFA) (By similarity). Negatively regulates replication in pancreatic beta-cells, resulting in apoptosis, loss of beta-cells and diabetes (By similarity). Through phosphorylation of the anti-apoptotic protein MCL1, may control cell apoptosis in response to growth factors deprivation (By similarity). Phosphorylates MUC1 in breast cancer cells, decreasing the interaction of MUC1 with CTNNB1/beta-catenin. Is necessary for the establishment of neuronal polarity and axon outgrowth. Phosphorylates MARK2, leading to inhibit its activity (By similarity). Phosphorylates SIK1 at 'Thr-182', leading to sustain its activity. Phosphorylates ZC3HAV1 which enhances its antiviral activity. Phosphorylates SNAI1, leading to its BTRC-triggered ubiquitination and proteasomal degradation. Phosphorylates SFPQ at 'Thr-687' upon T-cell activation. Phosphorylates NR1D1 st 'Ser-55' and 'Ser-59' and stabilizes it by protecting it from proteasomal degradation. Regulates the circadian clock via phosphorylation of the major clock components including ARNTL/BMAL1, CLOCK and PER2. Phosphorylates CLOCK AT 'Ser-427' and targets it for proteasomal degradation. Phosphorylates ARNTL/BMAL1 at 'Ser-17' and 'Ser-21' and primes it for ubiquitination and proteasomal degradation. Phosphorylates OGT at 'Ser-3' or 'Ser-4' which positively regulates its activity. Phosphorylates MYCN in neuroblastoma cells which may promote its degradation. Regulates the circadian rhythmicity of hippocampal long-term potentiation and ARNTL/BMLA1 and PER2 expression (By similarity). Acts as a regulator of autophagy by mediating phosphorylation of KAT5/TIP60 under starvation conditions, leading to activate KAT5/TIP60 acetyltransferase activity and promote acetylation of key autophagy regulators, such as ULK1 and RUBCNL/Pacer. Negatively regulates extrinsic apoptotic signaling pathway via death domain receptors. Promotes the formation of an anti-apoptotic complex, made of DDX3X, BRIC2 and GSK3B, at death receptors, including TNFRSF10B. The anti-apoptotic function is most effective with weak apoptotic signals and can be overcome by stronger stimulation. Phosphorylates E2F1, promoting the interaction between E2F1 and USP11, leading to stabilize E2F1 and promote its activity.
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Gene ID 2932
Uniprot ID
GSK3B_HUMAN
HGNC ID
HGNC:4617
KEGG ID
hsa:2932
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
GSK3B can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
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Fat mass and obesity-associated protein (FTO) [ERASER]
 Regulator Info 
Representative RNA-seq result indicating the expression of this target gene regulated by FTO
Cell Line B16-OVA cell line Mus musculus
Treatment: shFTO B16-OVA cells
Control: shNC B16-OVA cells
 GSE154952
Regulation
logFC: 6.35E-01
p-value: 1.84E-09
More Results Click to View More RNA-seq Results
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [1]
Response Summary FTO expression significantly contributes to the phenotype conversion of VSMCs and the aortic dissecting aneurysm by the demethylation function (m6A), thereby providing a novel therapeutic target. Knockdown of FTO suppresses the Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B) levels and Klf5 expression regardless of AngII treatment.
Target Regulation Up regulation
Responsed Disease Aortic aneurysm or dissection ICD-11: BD50
 Disease Info 
Pathway Response Nucleotide excision repair hsa03420
Cell Process DNA repair
Cell proliferation and migration
In-vitro Model VSMC (Human aortic vascular smooth muscle cells)
Methyltransferase-like 14 (METTL14) [WRITER]
 Regulator Info 
Representative RNA-seq result indicating the expression of this target gene regulated by METTL14
Cell Line BMDM Mus musculus
Treatment: METTL14 knockout mice BMDM
Control: Wild type mice BMDM
 GSE153512
Regulation
logFC: 1.08E+00
p-value: 1.69E-24
More Results Click to View More RNA-seq Results
In total 3 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [2]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B) and activates beta-catenin/TCF4-SLC7A11/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Target Regulation Down regulation
Responsed Disease Breast cancer ICD-11: 2C60
 Disease Info 
Responsed Drug Pertuzumab Approved
 Drug Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Experiment 2 Reporting the m6A Methylation Regulator of This Target Gene [2]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B) and activates beta-catenin/TCF4-SLC7A11/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Target Regulation Down regulation
Responsed Disease Breast cancer ICD-11: 2C60
 Disease Info 
Responsed Drug Trastuzumab Approved
 Drug Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Experiment 3 Reporting the m6A Methylation Regulator of This Target Gene [2]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B) and activates beta-catenin/TCF4-SLC7A11/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Target Regulation Down regulation
Responsed Disease Breast cancer ICD-11: 2C60
 Disease Info 
Responsed Drug Tucatinib Approved
 Drug Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Breast cancer [ICD-11: 2C60]
 Disease Info 
In total 3 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [2]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B) and activates beta-catenin/TCF4-SLC7A11/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Responsed Disease Breast cancer [ICD-11: 2C60]
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Responsed Drug Pertuzumab Approved
 Drug Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Experiment 2 Reporting the m6A-centered Disease Response [2]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B) and activates beta-catenin/TCF4-SLC7A11/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Responsed Disease Breast cancer [ICD-11: 2C60]
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Responsed Drug Trastuzumab Approved
 Drug Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Experiment 3 Reporting the m6A-centered Disease Response [2]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B) and activates beta-catenin/TCF4-SLC7A11/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Responsed Disease Breast cancer [ICD-11: 2C60]
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Responsed Drug Tucatinib Approved
 Drug Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Aortic aneurysm or dissection [ICD-11: BD50]
 Disease Info 
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [1]
Response Summary FTO expression significantly contributes to the phenotype conversion of VSMCs and the aortic dissecting aneurysm by the demethylation function (m6A), thereby providing a novel therapeutic target. Knockdown of FTO suppresses the Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B) levels and Klf5 expression regardless of AngII treatment.
Responsed Disease Aortic aneurysm or dissection [ICD-11: BD50]
Target Regulator Fat mass and obesity-associated protein (FTO) ERASER
 Regulator Info 
Target Regulation Up regulation
Pathway Response Nucleotide excision repair hsa03420
Cell Process DNA repair
Cell proliferation and migration
In-vitro Model VSMC (Human aortic vascular smooth muscle cells)
Pertuzumab [Approved]
 Drug Info 
In total 1 item(s) under this drug
Experiment 1 Reporting the m6A-centered Drug Response [2]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B) and activates beta-catenin/TCF4-SLC7A11/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Responsed Disease Breast cancer ICD-11: 2C60
 Disease Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Trastuzumab [Approved]
 Drug Info 
In total 1 item(s) under this drug
Experiment 1 Reporting the m6A-centered Drug Response [2]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B) and activates beta-catenin/TCF4-SLC7A11/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Responsed Disease Breast cancer ICD-11: 2C60
 Disease Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Tucatinib [Approved]
 Drug Info 
In total 1 item(s) under this drug
Experiment 1 Reporting the m6A-centered Drug Response [2]
Response Summary m6A-hypomethylation regulated FGFR4 phosphorylates Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B) and activates beta-catenin/TCF4-SLC7A11/FPN1 signaling to drive anti-HER2 resistance. Knockdown of METTL14 significantly increased the expression level of FGFR4 in HER2-positive breast cancer cells. FGFR4 reduced the sensitivity of HER2-positive breast cancer to trastuzumab plus pertuzumab or tucatinib. These results pinpoint a mechanism of anti-HER2 resistance and provide a strategy for overcoming resistance via FGFR4 inhibition in recalcitrant HER2-positive breast cancer.
Target Regulator Methyltransferase-like 14 (METTL14) WRITER
 Regulator Info 
Target Regulation Down regulation
Responsed Disease Breast cancer ICD-11: 2C60
 Disease Info 
Pathway Response Wnt signaling pathway hsa04310
Cell Process Glutathione synthesis
In-vitro Model ZR-75-1 Invasive breast carcinoma Homo sapiens CVCL_0588
T-47D Invasive breast carcinoma Homo sapiens CVCL_0553
SUM-159 (A mesenchymal triple-negative breast cancer cell line)
SK-BR-3 Breast adenocarcinoma Homo sapiens CVCL_0033
MDA-MB-468 Breast adenocarcinoma Homo sapiens CVCL_0419
MDA-MB-453 Breast adenocarcinoma Homo sapiens CVCL_0418
MDA-MB-361 Breast adenocarcinoma Homo sapiens CVCL_0620
MDA-MB-231 Breast adenocarcinoma Homo sapiens CVCL_0062
MCF-7 Invasive breast carcinoma Homo sapiens CVCL_0031
MCF-10A Normal Homo sapiens CVCL_0598
HEK293T Normal Homo sapiens CVCL_0063
BT-549 Invasive breast carcinoma Homo sapiens CVCL_1092
BT-474 Invasive breast carcinoma Homo sapiens CVCL_0179
AU565 Breast adenocarcinoma Homo sapiens CVCL_1074
In-vivo Model Luciferase-labeled rSKBR3 and MDA-MB-361 cells (1 × 107 cells) mixed with 1:1 Matrigel (Corning, 356237) were subcutaneously injected into the fat pads of mice. After a tumor was palpable, the mice were randomized into four groups (five mice per group), and they were treated with vehicle, trastuzumab (20 mg/kg, intraperitoneal administration), roblitinib (30 mg/kg, oral administration), or a combination of both drugs.
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
DNA modification
m6A Regulator: Methyltransferase-like 14 (METTL14)
 Regulator Info 
In total 9 item(s) under this m6A regulator
Crosstalk ID: M6ACROT02210
 Crosstalk Info 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 3B (DNMT3B)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Pertuzumab
 Drug Info 
Crosstalk ID: M6ACROT02218
 Crosstalk Info 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 3B (DNMT3B)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Tucatinib
 Drug Info 
Crosstalk ID: M6ACROT02223
 Crosstalk Info 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 3B (DNMT3B)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Trastuzumab
 Drug Info 
Crosstalk ID: M6ACROT02234
 Crosstalk Info 
Epigenetic Regulator Cysteine methyltransferase DNMT3A (DNMT3A)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Pertuzumab
 Drug Info 
Crosstalk ID: M6ACROT02242
 Crosstalk Info 
Epigenetic Regulator Cysteine methyltransferase DNMT3A (DNMT3A)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Tucatinib
 Drug Info 
Crosstalk ID: M6ACROT02247
 Crosstalk Info 
Epigenetic Regulator Cysteine methyltransferase DNMT3A (DNMT3A)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Trastuzumab
 Drug Info 
Crosstalk ID: M6ACROT02258
 Crosstalk Info 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 1 (DNMT1)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Pertuzumab
 Drug Info 
Crosstalk ID: M6ACROT02266
 Crosstalk Info 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 1 (DNMT1)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Tucatinib
 Drug Info 
Crosstalk ID: M6ACROT02271
 Crosstalk Info 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 1 (DNMT1)
Regulated Target Methyltransferase-like protein 14 (METTL14)
Crosstalk relationship DNA modification → m6A
Disease Breast cancer
 Disease Info 
Drug Trastuzumab
 Drug Info 
Non-coding RNA
m6A Regulator: YTH domain-containing family protein 2 (YTHDF2)
 Regulator Info 
In total 1 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05278
 Crosstalk Info 
Epigenetic Regulator hsa-miR-6125
Regulated Target YTH domain-containing family protein 2 (YTHDF2)
Crosstalk relationship ncRNA → m6A
Disease Colorectal cancer
 Disease Info 
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00268)
Glycogen synthase kinase-3 beta (GSK3Beta/GSK3B)
N4-acetylcytidine (ac4C)
In total 1 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000073 Click to Show/Hide the Full List
mod site chr3:119863466-119863467:- [5]
Sequence TACGGGACCCAAATGTCAAACTACCAAATGGGCGAGACACA
Cell/Tissue List H1
Seq Type List ac4C-seq
Transcript ID List ENST00000650344.1; ENST00000316626.5; ENST00000264235.12; ENST00000473886.1
External Link RMBase: ac4C_site_1391
Adenosine-to-Inosine editing (A-to-I)
In total 40 m6A sequence/site(s) in this target gene
mod ID: A2ISITE012015 Click to Show/Hide the Full List
mod site chr3:119824205-119824206:- [6]
Sequence AATAAAAAGCTCCTCACCAAATTCAAGCTTGTACATTATAT
Transcript ID List ENST00000264235.12
External Link RMBase: RNA-editing_site_98909
mod ID: A2ISITE012016 Click to Show/Hide the Full List
mod site chr3:119826351-119826352:- [7]
Sequence CTAGTGTGAGACTTTGGTATAGTGCACAGCTTGAAATTGGT
Transcript ID List ENST00000264235.12
External Link RMBase: RNA-editing_site_98910
mod ID: A2ISITE012017 Click to Show/Hide the Full List
mod site chr3:119843010-119843011:- [8]
Sequence AGACAGGAGAATTGCTTGAAACCGGGAGGCGGAGGTTGCAT
Transcript ID List ENST00000316626.5; ENST00000650344.1; ENST00000474830.1; ENST00000264235.12; rmsk_1074251; ENST00000473886.1
External Link RMBase: RNA-editing_site_98911
mod ID: A2ISITE012018 Click to Show/Hide the Full List
mod site chr3:119843011-119843012:- [8]
Sequence GAGACAGGAGAATTGCTTGAAACCGGGAGGCGGAGGTTGCA
Transcript ID List ENST00000264235.12; rmsk_1074251; ENST00000473886.1; ENST00000474830.1; ENST00000316626.5; ENST00000650344.1
External Link RMBase: RNA-editing_site_98912
mod ID: A2ISITE012019 Click to Show/Hide the Full List
mod site chr3:119843052-119843053:- [8]
Sequence TGTGGTGGCAGGTGCCTGTAATCCCAGCTTCTGGGGAGGCT
Transcript ID List ENST00000474830.1; ENST00000264235.12; ENST00000650344.1; ENST00000316626.5; rmsk_1074251; ENST00000473886.1
External Link RMBase: RNA-editing_site_98913
mod ID: A2ISITE012020 Click to Show/Hide the Full List
mod site chr3:119843063-119843064:- [8]
Sequence ACTTAGCCAGGTGTGGTGGCAGGTGCCTGTAATCCCAGCTT
Transcript ID List ENST00000474830.1; rmsk_1074251; ENST00000650344.1; ENST00000264235.12; ENST00000473886.1; ENST00000316626.5
External Link RMBase: RNA-editing_site_98914
mod ID: A2ISITE012021 Click to Show/Hide the Full List
mod site chr3:119843075-119843076:- [8]
Sequence CTAAAAATAAAAACTTAGCCAGGTGTGGTGGCAGGTGCCTG
Transcript ID List ENST00000473886.1; ENST00000650344.1; rmsk_1074251; ENST00000264235.12; ENST00000474830.1; ENST00000316626.5
External Link RMBase: RNA-editing_site_98915
mod ID: A2ISITE012022 Click to Show/Hide the Full List
mod site chr3:119843079-119843080:- [8]
Sequence TCTACTAAAAATAAAAACTTAGCCAGGTGTGGTGGCAGGTG
Transcript ID List ENST00000473886.1; ENST00000650344.1; ENST00000316626.5; rmsk_1074251; ENST00000474830.1; ENST00000264235.12
External Link RMBase: RNA-editing_site_98916
mod ID: A2ISITE012023 Click to Show/Hide the Full List
mod site chr3:119843089-119843090:- [8]
Sequence AAACCTTGTCTCTACTAAAAATAAAAACTTAGCCAGGTGTG
Transcript ID List rmsk_1074251; ENST00000650344.1; ENST00000264235.12; ENST00000474830.1; ENST00000316626.5; ENST00000473886.1
External Link RMBase: RNA-editing_site_98917
mod ID: A2ISITE012024 Click to Show/Hide the Full List
mod site chr3:119843107-119843108:- [8]
Sequence AGCCTGACCAACAAGGTGAAACCTTGTCTCTACTAAAAATA
Transcript ID List ENST00000474830.1; ENST00000316626.5; ENST00000650344.1; ENST00000473886.1; ENST00000264235.12; rmsk_1074251
External Link RMBase: RNA-editing_site_98918
mod ID: A2ISITE012025 Click to Show/Hide the Full List
mod site chr3:119843114-119843115:- [8]
Sequence TGAGACCAGCCTGACCAACAAGGTGAAACCTTGTCTCTACT
Transcript ID List ENST00000473886.1; ENST00000264235.12; ENST00000474830.1; ENST00000316626.5; rmsk_1074251; ENST00000650344.1
External Link RMBase: RNA-editing_site_98919
mod ID: A2ISITE012026 Click to Show/Hide the Full List
mod site chr3:119843118-119843119:- [8]
Sequence AGTTTGAGACCAGCCTGACCAACAAGGTGAAACCTTGTCTC
Transcript ID List ENST00000650344.1; ENST00000264235.12; ENST00000474830.1; ENST00000473886.1; rmsk_1074251; ENST00000316626.5
External Link RMBase: RNA-editing_site_98920
mod ID: A2ISITE012027 Click to Show/Hide the Full List
mod site chr3:119843121-119843122:- [8]
Sequence AGGAGTTTGAGACCAGCCTGACCAACAAGGTGAAACCTTGT
Transcript ID List ENST00000650344.1; ENST00000316626.5; ENST00000473886.1; ENST00000474830.1; ENST00000264235.12; rmsk_1074251
External Link RMBase: RNA-editing_site_98921
mod ID: A2ISITE012028 Click to Show/Hide the Full List
mod site chr3:119843127-119843128:- [8]
Sequence GAGGTCAGGAGTTTGAGACCAGCCTGACCAACAAGGTGAAA
Transcript ID List ENST00000650344.1; ENST00000316626.5; ENST00000264235.12; ENST00000474830.1; rmsk_1074251; ENST00000473886.1
External Link RMBase: RNA-editing_site_98922
mod ID: A2ISITE012029 Click to Show/Hide the Full List
mod site chr3:119843141-119843142:- [8]
Sequence TGGGTGGATCACCTGAGGTCAGGAGTTTGAGACCAGCCTGA
Transcript ID List ENST00000264235.12; ENST00000474830.1; ENST00000473886.1; rmsk_1074251; ENST00000650344.1; ENST00000316626.5
External Link RMBase: RNA-editing_site_98923
mod ID: A2ISITE012030 Click to Show/Hide the Full List
mod site chr3:119843178-119843179:- [8]
Sequence CTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGG
Transcript ID List ENST00000650344.1; ENST00000474830.1; ENST00000264235.12; rmsk_1074251; ENST00000473886.1; ENST00000316626.5
External Link RMBase: RNA-editing_site_98924
mod ID: A2ISITE012031 Click to Show/Hide the Full List
mod site chr3:119843181-119843182:- [8]
Sequence TGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGT
Transcript ID List ENST00000316626.5; ENST00000474830.1; rmsk_1074251; ENST00000650344.1; ENST00000264235.12; ENST00000473886.1
External Link RMBase: RNA-editing_site_98925
mod ID: A2ISITE012032 Click to Show/Hide the Full List
mod site chr3:119843193-119843194:- [8]
Sequence GGCTGGGCATGATGGCTCACACCTGTAATCCCAGCACTTTG
Transcript ID List ENST00000264235.12; ENST00000316626.5; ENST00000650344.1; ENST00000473886.1; ENST00000474830.1; rmsk_1074251
External Link RMBase: RNA-editing_site_98926
mod ID: A2ISITE012033 Click to Show/Hide the Full List
mod site chr3:119843202-119843203:- [8]
Sequence CATATTCTGGGCTGGGCATGATGGCTCACACCTGTAATCCC
Transcript ID List ENST00000650344.1; ENST00000264235.12; rmsk_1074251; ENST00000473886.1; ENST00000316626.5; ENST00000474830.1
External Link RMBase: RNA-editing_site_98927
mod ID: A2ISITE012034 Click to Show/Hide the Full List
mod site chr3:119843271-119843272:- [8]
Sequence AGCTGCTTCAACCCCCACAAATGCCACAGCAGCGTCAGGTA
Transcript ID List ENST00000473886.1; ENST00000316626.5; ENST00000474830.1; ENST00000650344.1; ENST00000264235.12
External Link RMBase: RNA-editing_site_98928
mod ID: A2ISITE012035 Click to Show/Hide the Full List
mod site chr3:119843272-119843273:- [8]
Sequence CAGCTGCTTCAACCCCCACAAATGCCACAGCAGCGTCAGGT
Transcript ID List ENST00000473886.1; ENST00000474830.1; ENST00000316626.5; ENST00000650344.1; ENST00000264235.12
External Link RMBase: RNA-editing_site_98929
mod ID: A2ISITE012036 Click to Show/Hide the Full List
mod site chr3:119878396-119878397:- [7]
Sequence GGTGGTATCTTGTTTTAATTAGCATTTCCCTAATGATTAAT
Transcript ID List ENST00000650344.1; ENST00000316626.5; ENST00000264235.12
External Link RMBase: RNA-editing_site_98930
mod ID: A2ISITE012037 Click to Show/Hide the Full List
mod site chr3:119878400-119878401:- [7]
Sequence ATATGGTGGTATCTTGTTTTAATTAGCATTTCCCTAATGAT
Transcript ID List ENST00000264235.12; ENST00000650344.1; ENST00000316626.5
External Link RMBase: RNA-editing_site_98931
mod ID: A2ISITE012038 Click to Show/Hide the Full List
mod site chr3:119878533-119878534:- [7]
Sequence AACTTCCAAACTGTTTTCCAAGGTGCTATATACCATTTCAC
Transcript ID List ENST00000264235.12; ENST00000316626.5; ENST00000650344.1
External Link RMBase: RNA-editing_site_98932
mod ID: A2ISITE012039 Click to Show/Hide the Full List
mod site chr3:119880225-119880226:- [7]
Sequence AGGTATATGAGAGGTGCTCAACATCATTGATCATCAGAGAA
Transcript ID List rmsk_1074303; ENST00000316626.5; ENST00000264235.12; ENST00000650344.1
External Link RMBase: RNA-editing_site_98933
mod ID: A2ISITE012040 Click to Show/Hide the Full List
mod site chr3:119959576-119959577:- [8]
Sequence GGTTGCAGTGAGCTGAGATCATGCCACTGCACTCCAGCCTG
Transcript ID List ENST00000650344.1; ENST00000316626.5; rmsk_1074450; ENST00000264235.12
External Link RMBase: RNA-editing_site_98934
mod ID: A2ISITE012041 Click to Show/Hide the Full List
mod site chr3:119959610-119959611:- [8]
Sequence GAGGCAGGAGAATCACTTGAACCTGGGAGACAGAGGTTGCA
Transcript ID List rmsk_1074450; ENST00000264235.12; ENST00000650344.1; ENST00000316626.5
External Link RMBase: RNA-editing_site_98935
mod ID: A2ISITE012042 Click to Show/Hide the Full List
mod site chr3:119959611-119959612:- [8]
Sequence TGAGGCAGGAGAATCACTTGAACCTGGGAGACAGAGGTTGC
Transcript ID List ENST00000650344.1; ENST00000264235.12; rmsk_1074450; ENST00000316626.5
External Link RMBase: RNA-editing_site_98936
mod ID: A2ISITE012043 Click to Show/Hide the Full List
mod site chr3:119959625-119959626:- [8]
Sequence GCTACTCAGGAGGCTGAGGCAGGAGAATCACTTGAACCTGG
Transcript ID List rmsk_1074450; ENST00000316626.5; ENST00000650344.1; ENST00000264235.12
External Link RMBase: RNA-editing_site_98937
mod ID: A2ISITE012044 Click to Show/Hide the Full List
mod site chr3:119959638-119959639:- [8]
Sequence GCGTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAAT
Transcript ID List rmsk_1074450; ENST00000650344.1; ENST00000264235.12; ENST00000316626.5
External Link RMBase: RNA-editing_site_98938
mod ID: A2ISITE012045 Click to Show/Hide the Full List
mod site chr3:119959642-119959643:- [8]
Sequence ACACGCGTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGA
Transcript ID List ENST00000650344.1; rmsk_1074450; ENST00000316626.5; ENST00000264235.12
External Link RMBase: RNA-editing_site_98939
mod ID: A2ISITE012046 Click to Show/Hide the Full List
mod site chr3:119959646-119959647:- [8]
Sequence TGGTACACGCGTGTAATCCCAGCTACTCAGGAGGCTGAGGC
Transcript ID List ENST00000316626.5; rmsk_1074450; ENST00000264235.12; ENST00000650344.1
External Link RMBase: RNA-editing_site_98940
mod ID: A2ISITE012047 Click to Show/Hide the Full List
mod site chr3:119959652-119959653:- [8]
Sequence GCATGGTGGTACACGCGTGTAATCCCAGCTACTCAGGAGGC
Transcript ID List ENST00000316626.5; ENST00000650344.1; ENST00000264235.12; rmsk_1074450
External Link RMBase: RNA-editing_site_98941
mod ID: A2ISITE012048 Click to Show/Hide the Full List
mod site chr3:119959685-119959686:- [8]
Sequence CATCTCTACTAAAAATACAAAAAAATTAGCTGGGCATGGTG
Transcript ID List ENST00000264235.12; ENST00000650344.1; rmsk_1074450; ENST00000316626.5
External Link RMBase: RNA-editing_site_98942
mod ID: A2ISITE012049 Click to Show/Hide the Full List
mod site chr3:119959694-119959695:- [8]
Sequence GTGAAACCCCATCTCTACTAAAAATACAAAAAAATTAGCTG
Transcript ID List rmsk_1074450; ENST00000316626.5; ENST00000264235.12; ENST00000650344.1
External Link RMBase: RNA-editing_site_98943
mod ID: A2ISITE012050 Click to Show/Hide the Full List
mod site chr3:119959695-119959696:- [8]
Sequence GGTGAAACCCCATCTCTACTAAAAATACAAAAAAATTAGCT
Transcript ID List ENST00000264235.12; ENST00000650344.1; ENST00000316626.5; rmsk_1074450
External Link RMBase: RNA-editing_site_98944
mod ID: A2ISITE012051 Click to Show/Hide the Full List
mod site chr3:119971144-119971145:- [7]
Sequence CCTAGATTGCTTCAACTTCAATCCATTTGGGGAATTTTGGA
Transcript ID List ENST00000650344.1; ENST00000316626.5; ENST00000264235.12
External Link RMBase: RNA-editing_site_98945
mod ID: A2ISITE012052 Click to Show/Hide the Full List
mod site chr3:120027293-120027294:- [7]
Sequence ACCTCCACCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCC
Transcript ID List ENST00000264235.12; ENST00000650344.1; ENST00000316626.5
External Link RMBase: RNA-editing_site_98946
mod ID: A2ISITE012053 Click to Show/Hide the Full List
mod site chr3:120029082-120029083:- [9]
Sequence TGATTCATATTGCCAAATAGTAGCTGATCCAAATGCACAGC
Transcript ID List ENST00000264235.12; ENST00000316626.5; ENST00000650344.1
External Link RMBase: RNA-editing_site_98947
mod ID: A2ISITE012054 Click to Show/Hide the Full List
mod site chr3:120074059-120074060:- [7]
Sequence TATCCACCTCGGCCTCCCATAGTGCTGGGATTACAGTCGTG
Transcript ID List ENST00000650344.1; ENST00000316626.5; ENST00000264235.12
External Link RMBase: RNA-editing_site_98948
5-methylcytidine (m5C)
In total 1 m6A sequence/site(s) in this target gene
mod ID: M5CSITE003140 Click to Show/Hide the Full List
mod site chr3:119876478-119876479:- [10]
Sequence ACTCCAACAAGGGAGCAAATCAGAGAAATGAACCCAAACTA
Seq Type List Bisulfite-seq
Transcript ID List ENST00000264235.12; ENST00000316626.5; ENST00000473886.1; ENST00000650344.1
External Link RMBase: m5C_site_32712
N6-methyladenosine (m6A)
In total 116 m6A sequence/site(s) in this target gene
mod ID: M6ASITE062167 Click to Show/Hide the Full List
mod site chr3:119821819-119821820:- [11]
Sequence ATTAATCTTTGTTATACAGAACAAGATATCAATACCACTTC
Motif Score 2.951386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604622
mod ID: M6ASITE062168 Click to Show/Hide the Full List
mod site chr3:119821841-119821842:- [11]
Sequence CCATTCCTCTAATTAGGGAAACATTAATCTTTGTTATACAG
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604623
mod ID: M6ASITE062169 Click to Show/Hide the Full List
mod site chr3:119822046-119822047:- [12]
Sequence TTCCCCATTCCCTTGTAAATACATTTTGTTCTATGTGACTT
Motif Score 2.110482143
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604624
mod ID: M6ASITE062170 Click to Show/Hide the Full List
mod site chr3:119822161-119822162:- [12]
Sequence GGAAAAGCAAAATCTGTATAACATTATTACTACTTGAATGC
Motif Score 2.168095238
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604625
mod ID: M6ASITE062171 Click to Show/Hide the Full List
mod site chr3:119822210-119822211:- [12]
Sequence TTGTATACAAACTATTGCAAACACTTGTGCAAATCTGTCTT
Motif Score 2.20572619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604626
mod ID: M6ASITE062172 Click to Show/Hide the Full List
mod site chr3:119822290-119822291:- [11]
Sequence TGACCACTTCCATCTTAAAAACAAACCTAAAAAACAAAATT
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604627
mod ID: M6ASITE062173 Click to Show/Hide the Full List
mod site chr3:119822327-119822328:- [13]
Sequence GATGGATCACTTGGGCCTGTACACATACCAATTAGCGTGAC
Motif Score 2.856142857
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604628
mod ID: M6ASITE062174 Click to Show/Hide the Full List
mod site chr3:119822475-119822476:- [12]
Sequence GTACATAAGGGGTTAGCTTGACAAAGTAGACTTCCTTGTGT
Motif Score 2.859755952
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604629
mod ID: M6ASITE062175 Click to Show/Hide the Full List
mod site chr3:119822502-119822503:- [12]
Sequence TCTGCAATAAAAGCAAAATGACAACCAGTACATAAGGGGTT
Motif Score 2.859755952
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604630
mod ID: M6ASITE062176 Click to Show/Hide the Full List
mod site chr3:119822569-119822570:- [12]
Sequence CTGGGGTTTGGATTATTTTCACAAGGGTTATGCCGTTTTAT
Motif Score 2.047297619
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604631
mod ID: M6ASITE062177 Click to Show/Hide the Full List
mod site chr3:119822626-119822627:- [11]
Sequence GAAGCACAGTAGAGTCCCAGACTGAGATCTACCTTTGAGAG
Motif Score 3.319380952
Cell/Tissue List HeLa; HEK293T
Seq Type List m6A-seq; DART-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604632
mod ID: M6ASITE062178 Click to Show/Hide the Full List
mod site chr3:119822653-119822654:- [11]
Sequence AGCCACTGAAAATAAAAGAGACAACTAGAAGCACAGTAGAG
Motif Score 2.897386905
Cell/Tissue List HeLa; HEK293T; hESC-HEK293T
Seq Type List m6A-seq; DART-seq; MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604633
mod ID: M6ASITE062179 Click to Show/Hide the Full List
mod site chr3:119822678-119822679:- [11]
Sequence ATCTGTCTTTTCTGGTAGAAACCTGAGCCACTGAAAATAAA
Motif Score 2.185083333
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604634
mod ID: M6ASITE062180 Click to Show/Hide the Full List
mod site chr3:119822706-119822707:- [12]
Sequence TGGAAAAGTAGGTATGCTTTACAATAAAATCTGTCTTTTCT
Motif Score 2.07285119
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604635
mod ID: M6ASITE062181 Click to Show/Hide the Full List
mod site chr3:119822744-119822745:- [11]
Sequence TCATCTAATCACAGAGCCAAACACTTTTCTCCCCTGTGTGG
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604636
mod ID: M6ASITE062182 Click to Show/Hide the Full List
mod site chr3:119822781-119822782:- [13]
Sequence TGAAATTGTATCTGATTCCTACTGTTCATGTTAGTGATCAT
Motif Score 2.500660714
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604637
mod ID: M6ASITE062183 Click to Show/Hide the Full List
mod site chr3:119822803-119822804:- [13]
Sequence GGGGGTTTTCTTTCTTTTCAACTGAAATTGTATCTGATTCC
Motif Score 2.595904762
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604638
mod ID: M6ASITE062184 Click to Show/Hide the Full List
mod site chr3:119822922-119822923:- [13]
Sequence CTATCCCTGTGGATATGAAGACACTGGCATTTCATCTATTT
Motif Score 2.897386905
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604639
mod ID: M6ASITE062185 Click to Show/Hide the Full List
mod site chr3:119823029-119823030:- [11]
Sequence TAAGTCCTCTTAATTTTTAGACACATTTTTGGTTTATGTTT
Motif Score 2.897386905
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604640
mod ID: M6ASITE062186 Click to Show/Hide the Full List
mod site chr3:119823069-119823070:- [12]
Sequence ACTGCACCTTCTTTCCAGTGACATGCTGTGTCATTTTTTTT
Motif Score 2.859755952
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604641
mod ID: M6ASITE062187 Click to Show/Hide the Full List
mod site chr3:119823089-119823090:- [11]
Sequence TCATTCCAGCAAGGCAGAAGACTGCACCTTCTTTCCAGTGA
Motif Score 3.319380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604642
mod ID: M6ASITE062188 Click to Show/Hide the Full List
mod site chr3:119823120-119823121:- [11]
Sequence CAAAGGTTACTATTTTTGAAACATCGTGTGTTCATTCCAGC
Motif Score 2.20572619
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604643
mod ID: M6ASITE062189 Click to Show/Hide the Full List
mod site chr3:119823142-119823143:- [11]
Sequence ATAGAAGAAAAAACTACCAAACCAAAGGTTACTATTTTTGA
Motif Score 2.185083333
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604644
mod ID: M6ASITE062190 Click to Show/Hide the Full List
mod site chr3:119823150-119823151:- [11]
Sequence TGTCTTGAATAGAAGAAAAAACTACCAAACCAAAGGTTACT
Motif Score 2.627720238
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604645
mod ID: M6ASITE062191 Click to Show/Hide the Full List
mod site chr3:119823231-119823232:- [12]
Sequence TAATTCTTACTGTGTGCCCAACACGAAGGCCTTTTTTGAAA
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604646
mod ID: M6ASITE062192 Click to Show/Hide the Full List
mod site chr3:119823335-119823336:- [11]
Sequence ACTGTTGTTTTAACAAGGGAACTCTTAGCCCATTTCCTCCC
Motif Score 3.373380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604647
mod ID: M6ASITE062193 Click to Show/Hide the Full List
mod site chr3:119823355-119823356:- [11]
Sequence TGCCACCGTGCCAATAGAGGACTGTTGTTTTAACAAGGGAA
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604648
mod ID: M6ASITE062194 Click to Show/Hide the Full List
mod site chr3:119823556-119823557:- [11]
Sequence CCTAACCATGGGTCTTAAAAACAGCAGATTCTGGGAGCCTT
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604649
mod ID: M6ASITE062195 Click to Show/Hide the Full List
mod site chr3:119823652-119823653:- [11]
Sequence CATACTTAGTCCATTCAGGGACTTAGTGTAGCACCAGGGAG
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604650
mod ID: M6ASITE062196 Click to Show/Hide the Full List
mod site chr3:119823685-119823686:- [11]
Sequence TCCTCCTCGGTAGCAGTGAGACCGGTTTCATTTCATACTTA
Motif Score 2.876744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604651
mod ID: M6ASITE062197 Click to Show/Hide the Full List
mod site chr3:119823990-119823991:- [12]
Sequence TACCGGCCTGTATTATTGTAACAATAACTCTAGCAATGTAT
Motif Score 2.168095238
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604652
mod ID: M6ASITE062198 Click to Show/Hide the Full List
mod site chr3:119824018-119824019:- [13]
Sequence CCATATAGTTTTAACTCTGTACAGTAGGTACCGGCCTGTAT
Motif Score 2.856142857
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604653
mod ID: M6ASITE062199 Click to Show/Hide the Full List
mod site chr3:119824064-119824065:- [11]
Sequence TGATTCTGTTTAATAATCAGACAAAATGTAGACGAGCTTTT
Motif Score 2.897386905
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604654
mod ID: M6ASITE062200 Click to Show/Hide the Full List
mod site chr3:119824122-119824123:- [11]
Sequence GTAAATATGTGGACCCAGGAACTGTTATTAATGAGCAAAAA
Motif Score 3.373380952
Cell/Tissue List HeLa; HEK293T
Seq Type List m6A-seq; DART-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604655
mod ID: M6ASITE062201 Click to Show/Hide the Full List
mod site chr3:119824130-119824131:- [11]
Sequence TTTTGTATGTAAATATGTGGACCCAGGAACTGTTATTAATG
Motif Score 3.622404762
Cell/Tissue List HeLa; HEK293T
Seq Type List m6A-seq; DART-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604656
mod ID: M6ASITE062202 Click to Show/Hide the Full List
mod site chr3:119824193-119824194:- [12]
Sequence CTCACCAAATTCAAGCTTGTACATTATATTTTCTTTCTGTG
Motif Score 2.856142857
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604657
mod ID: M6ASITE062203 Click to Show/Hide the Full List
mod site chr3:119824270-119824271:- [12]
Sequence GGATCACAGAACTCTTTTATACAAGTGAGATCCAGGTCTCT
Motif Score 2.110482143
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604658
mod ID: M6ASITE062204 Click to Show/Hide the Full List
mod site chr3:119824280-119824281:- [11]
Sequence GATCATGGTGGGATCACAGAACTCTTTTATACAAGTGAGAT
Motif Score 3.373380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604659
mod ID: M6ASITE062205 Click to Show/Hide the Full List
mod site chr3:119824432-119824433:- [11]
Sequence ATCAGTGCTTATTTTAGGAAACAGGTTGCCCCCCACAACTG
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604660
mod ID: M6ASITE062206 Click to Show/Hide the Full List
mod site chr3:119824493-119824494:- [11]
Sequence CAGCAAGCGTTTGGATGCAGACACTGCTCTGGACGTGGTAT
Motif Score 2.897386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604661
mod ID: M6ASITE062207 Click to Show/Hide the Full List
mod site chr3:119824536-119824537:- [11]
Sequence GGTCTGTGATAGAGAAATGGACCTGCATTCAGATCCAACTG
Motif Score 3.622404762
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604662
mod ID: M6ASITE062208 Click to Show/Hide the Full List
mod site chr3:119824585-119824586:- [11]
Sequence CGTTGATAGACCATTTTCAGACAGAATTTATAAAGAATCTG
Motif Score 2.897386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604663
mod ID: M6ASITE062209 Click to Show/Hide the Full List
mod site chr3:119824596-119824597:- [11]
Sequence AAAGGTAGTGGCGTTGATAGACCATTTTCAGACAGAATTTA
Motif Score 2.876744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604664
mod ID: M6ASITE062210 Click to Show/Hide the Full List
mod site chr3:119824623-119824624:- [13]
Sequence TCAAAGTATTTGGCAGCATAACTCCTTAAAGGTAGTGGCGT
Motif Score 2.590089286
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604665
mod ID: M6ASITE062211 Click to Show/Hide the Full List
mod site chr3:119824706-119824707:- [14]
Sequence GCTCAGTCAAACCAAATCAAACAAATTGAATTTTATGTTTT
Motif Score 2.20572619
Cell/Tissue List peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604666
mod ID: M6ASITE062212 Click to Show/Hide the Full List
mod site chr3:119824716-119824717:- [14]
Sequence AAGGAAACATGCTCAGTCAAACCAAATCAAACAAATTGAAT
Motif Score 2.185083333
Cell/Tissue List peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604667
mod ID: M6ASITE062213 Click to Show/Hide the Full List
mod site chr3:119824730-119824731:- [14]
Sequence CAGAGTTTATGAGAAAGGAAACATGCTCAGTCAAACCAAAT
Motif Score 2.20572619
Cell/Tissue List peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604668
mod ID: M6ASITE062214 Click to Show/Hide the Full List
mod site chr3:119824764-119824765:- [14]
Sequence CCACAAAAGGGGTTTCACAAACCTCTGGATATATCAGAGTT
Motif Score 2.185083333
Cell/Tissue List peripheral-blood
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604669
mod ID: M6ASITE062215 Click to Show/Hide the Full List
mod site chr3:119825212-119825213:- [11]
Sequence CCTTATATACTCTAAAATGAACTTTAGTCACCTTGGTGCTT
Motif Score 3.373380952
Cell/Tissue List HeLa; HEK293T
Seq Type List m6A-seq; DART-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604670
mod ID: M6ASITE062216 Click to Show/Hide the Full List
mod site chr3:119825456-119825457:- [13]
Sequence TGTCTACAGTATCAAAATTGACTGGTTGAAGCATGAGAAGA
Motif Score 3.28175
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604671
mod ID: M6ASITE062217 Click to Show/Hide the Full List
mod site chr3:119825587-119825588:- [12]
Sequence TGGTAGAAATATTAAAAACTACACATCAGAATGATACAGTC
Motif Score 2.078666667
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604672
mod ID: M6ASITE062218 Click to Show/Hide the Full List
mod site chr3:119825633-119825634:- [12]
Sequence TTTTTAACCTCATGCTTTTTACATTTATTTATTGATGCATG
Motif Score 2.07285119
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604673
mod ID: M6ASITE062219 Click to Show/Hide the Full List
mod site chr3:119825801-119825802:- [11]
Sequence GGAAAGATACACTTGAGAGGACATTGTAGTTAAATAATGTG
Motif Score 3.643047619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604674
mod ID: M6ASITE062220 Click to Show/Hide the Full List
mod site chr3:119825890-119825891:- [11]
Sequence GATGAGCCCAGAGGAAGGGGACAGGTCAGGGATACATCTCA
Motif Score 3.643047619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604675
mod ID: M6ASITE062221 Click to Show/Hide the Full List
mod site chr3:119825977-119825978:- [11]
Sequence AAATCTTAGCACAGTTTCAAACTAGTGACCTGGGAGGAGAT
Motif Score 2.627720238
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604676
mod ID: M6ASITE062222 Click to Show/Hide the Full List
mod site chr3:119826046-119826047:- [12]
Sequence GCAGCAAGCAAGACTCAGGCACACATGCTCTACAGGTGGCT
Motif Score 2.830589286
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604677
mod ID: M6ASITE062223 Click to Show/Hide the Full List
mod site chr3:119826054-119826055:- [11]
Sequence GAGGGGAAGCAGCAAGCAAGACTCAGGCACACATGCTCTAC
Motif Score 3.319380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604678
mod ID: M6ASITE062224 Click to Show/Hide the Full List
mod site chr3:119826088-119826089:- [15]
Sequence CTAGTGATGTAGAGGCTTGTACAGGAGGCTGCCAGAGGGGA
Motif Score 2.856142857
Cell/Tissue List brain
Seq Type List m6A-REF-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604679
mod ID: M6ASITE062225 Click to Show/Hide the Full List
mod site chr3:119826167-119826168:- [11]
Sequence GGAGGTCAATAAAGTTTGGAACTCTACAGGGAAGATTCTTA
Motif Score 3.373380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604680
mod ID: M6ASITE062226 Click to Show/Hide the Full List
mod site chr3:119826217-119826218:- [11]
Sequence GTTGGTGGCAGGTGTGGCAGACAAAGAAATGTGTATCATTC
Motif Score 2.897386905
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604681
mod ID: M6ASITE062227 Click to Show/Hide the Full List
mod site chr3:119826252-119826253:- [11]
Sequence ATATCTTCGGGTATTTATAGACTTGCCTTTGGCATGTTGGT
Motif Score 3.319380952
Cell/Tissue List HeLa; HEK293T
Seq Type List m6A-seq; DART-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604682
mod ID: M6ASITE062228 Click to Show/Hide the Full List
mod site chr3:119826300-119826301:- [11]
Sequence GCAGGTATAACTCAACGGGGACTTAAATGTCACTTGTAAAA
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604683
mod ID: M6ASITE062229 Click to Show/Hide the Full List
mod site chr3:119826361-119826362:- [11]
Sequence CTTTTAAAGTCTAGTGTGAGACTTTGGTATAGTGCACAGCT
Motif Score 3.319380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604684
mod ID: M6ASITE062230 Click to Show/Hide the Full List
mod site chr3:119826391-119826392:- [11]
Sequence GTGCTGATGGGTTTTTTTGAACTTTGTTTTCTTTTAAAGTC
Motif Score 3.373380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604685
mod ID: M6ASITE062231 Click to Show/Hide the Full List
mod site chr3:119826421-119826422:- [11]
Sequence CCCTTCCACAAAAGAAGAAAACCTTTTTCTGTGCTGATGGG
Motif Score 2.185083333
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604686
mod ID: M6ASITE062232 Click to Show/Hide the Full List
mod site chr3:119826456-119826457:- [11]
Sequence TTGTATACTTTAAAAACAGGACTCCTGCCTCATGCCCCTTC
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604687
mod ID: M6ASITE062233 Click to Show/Hide the Full List
mod site chr3:119826461-119826462:- [11]
Sequence TGCTGTTGTATACTTTAAAAACAGGACTCCTGCCTCATGCC
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604688
mod ID: M6ASITE062234 Click to Show/Hide the Full List
mod site chr3:119826504-119826505:- [12]
Sequence CATACAATCTCTCTCCCACGACAATCTTTTTTTATTAAAAG
Motif Score 2.865571429
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604689
mod ID: M6ASITE062235 Click to Show/Hide the Full List
mod site chr3:119826606-119826607:- [13]
Sequence TAAAATATCTATAAATACAAACCAATTTCATTGTATTCTCA
Motif Score 2.185083333
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604690
mod ID: M6ASITE062236 Click to Show/Hide the Full List
mod site chr3:119826610-119826611:- [13]
Sequence CTTGTAAAATATCTATAAATACAAACCAATTTCATTGTATT
Motif Score 2.110482143
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604691
mod ID: M6ASITE062237 Click to Show/Hide the Full List
mod site chr3:119826726-119826727:- [12]
Sequence TACTTGAGTGTCACTCAGCAACACTGGTCACGTTTGGAAAG
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000650344.1; ENST00000316626.5; ENST00000264235.12; ENST00000474830.1; ENST00000473886.1
External Link RMBase: m6A_site_604692
mod ID: M6ASITE062238 Click to Show/Hide the Full List
mod site chr3:119826755-119826756:- [11]
Sequence CAGCCAGCTGCACAGGAAAAACCACCAGTTACTTGAGTGTC
Motif Score 2.185083333
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000474830.1; ENST00000650344.1; ENST00000264235.12; ENST00000316626.5; ENST00000473886.1
External Link RMBase: m6A_site_604693
mod ID: M6ASITE062239 Click to Show/Hide the Full List
mod site chr3:119826786-119826787:- [11]
Sequence CAGCTTCCAACTCCACCTGAACAGTCCCGAGCAGCCAGCTG
Motif Score 2.951386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000473886.1; ENST00000650344.1; ENST00000316626.5; ENST00000474830.1; ENST00000264235.12
External Link RMBase: m6A_site_604694
mod ID: M6ASITE062240 Click to Show/Hide the Full List
mod site chr3:119826832-119826833:- [11]
Sequence GCTAATACTGGAGACCGTGGACAGACCAATAATGCTGCTTC
Motif Score 3.643047619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12; ENST00000650344.1; ENST00000316626.5; ENST00000474830.1; ENST00000473886.1
External Link RMBase: m6A_site_604695
mod ID: M6ASITE062241 Click to Show/Hide the Full List
mod site chr3:119843275-119843276:- [12]
Sequence AAGCAGCTGCTTCAACCCCCACAAATGCCACAGCAGCGTCA
Motif Score 2.053113095
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000316626.5; ENST00000473886.1; ENST00000650344.1; ENST00000474830.1; ENST00000264235.12
External Link RMBase: m6A_site_604696
mod ID: M6ASITE062242 Click to Show/Hide the Full List
mod site chr3:119843351-119843352:- [16]
Sequence GTGTCTTAACCTTCTATAGAACTGTCAAGTAATCCACCTCT
Motif Score 3.373380952
Cell/Tissue List Huh7
Seq Type List MeRIP-seq
Transcript ID List ENST00000316626.5; ENST00000474830.1; ENST00000473886.1; ENST00000650344.1; ENST00000264235.12
External Link RMBase: m6A_site_604697
mod ID: M6ASITE062243 Click to Show/Hide the Full List
mod site chr3:119843383-119843384:- [16]
Sequence GCATACAAAGTTAAGAGTGGACTCTAACATTTGTGTCTTAA
Motif Score 4.065041667
Cell/Tissue List Huh7
Seq Type List MeRIP-seq
Transcript ID List ENST00000264235.12; ENST00000474830.1; ENST00000650344.1; ENST00000316626.5; ENST00000473886.1
External Link RMBase: m6A_site_604698
mod ID: M6ASITE062244 Click to Show/Hide the Full List
mod site chr3:119863450-119863451:- [11]
Sequence CAAACTACCAAATGGGCGAGACACACCTGCACTCTTCAACT
Motif Score 2.897386905
Cell/Tissue List HeLa; MT4; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000473886.1; ENST00000264235.12; ENST00000650344.1; ENST00000316626.5
External Link RMBase: m6A_site_604699
mod ID: M6ASITE062245 Click to Show/Hide the Full List
mod site chr3:119863467-119863468:- [11]
Sequence TTACGGGACCCAAATGTCAAACTACCAAATGGGCGAGACAC
Motif Score 2.627720238
Cell/Tissue List HeLa; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000316626.5; ENST00000473886.1; ENST00000264235.12; ENST00000650344.1
External Link RMBase: m6A_site_604700
mod ID: M6ASITE062246 Click to Show/Hide the Full List
mod site chr3:119863480-119863481:- [11]
Sequence ATTTTTTGATGAATTACGGGACCCAAATGTCAAACTACCAA
Motif Score 3.622404762
Cell/Tissue List HeLa; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000473886.1; ENST00000264235.12; ENST00000650344.1; ENST00000316626.5
External Link RMBase: m6A_site_604701
mod ID: M6ASITE062247 Click to Show/Hide the Full List
mod site chr3:119863530-119863531:- [13]
Sequence GAGTATACACCAACTGCCCGACTAACACCACTGGAAGCTTG
Motif Score 3.287565476
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000473886.1; ENST00000264235.12; ENST00000650344.1; ENST00000316626.5
External Link RMBase: m6A_site_604702
mod ID: M6ASITE062248 Click to Show/Hide the Full List
mod site chr3:119863544-119863545:- [12]
Sequence GTAGCCGTCTGCTGGAGTATACACCAACTGCCCGACTAACA
Motif Score 2.110482143
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12; ENST00000650344.1; ENST00000316626.5; ENST00000473886.1
External Link RMBase: m6A_site_604703
mod ID: M6ASITE062249 Click to Show/Hide the Full List
mod site chr3:119863569-119863570:- [13]
Sequence ACTCCACCGGAGGCAATTGCACTGTGTAGCCGTCTGCTGGA
Motif Score 3.252583333
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000264235.12; ENST00000650344.1; ENST00000473886.1; ENST00000316626.5
External Link RMBase: m6A_site_604704
mod ID: M6ASITE062250 Click to Show/Hide the Full List
mod site chr3:119863589-119863590:- [11]
Sequence TGCAGGTCTTCCGACCCCGAACTCCACCGGAGGCAATTGCA
Motif Score 3.373380952
Cell/Tissue List HeLa; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000473886.1; ENST00000650344.1; ENST00000316626.5; ENST00000264235.12
External Link RMBase: m6A_site_604705
mod ID: M6ASITE062251 Click to Show/Hide the Full List
mod site chr3:119866610-119866611:- [11]
Sequence TAGGATTCGTCAGGAACAGGACATTTCACCTCAGGAGTGCG
Motif Score 3.643047619
Cell/Tissue List HeLa; hESC-HEK293T; Huh7
Seq Type List m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List ENST00000264235.12; ENST00000473886.1; ENST00000650344.1; ENST00000316626.5
External Link RMBase: m6A_site_604706
mod ID: M6ASITE062252 Click to Show/Hide the Full List
mod site chr3:119866615-119866616:- [11]
Sequence ATCTTTAGGATTCGTCAGGAACAGGACATTTCACCTCAGGA
Motif Score 2.951386905
Cell/Tissue List HeLa; Huh7
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000316626.5; ENST00000473886.1; ENST00000264235.12; ENST00000650344.1
External Link RMBase: m6A_site_604707
mod ID: M6ASITE062253 Click to Show/Hide the Full List
mod site chr3:119876417-119876418:- [16]
Sequence AAATTAAGGCACATCCTTGGACTAAGGTGAGTTAGATTTTT
Motif Score 4.065041667
Cell/Tissue List Huh7
Seq Type List MeRIP-seq
Transcript ID List ENST00000316626.5; ENST00000650344.1; ENST00000473886.1; ENST00000264235.12
External Link RMBase: m6A_site_604708
mod ID: M6ASITE062254 Click to Show/Hide the Full List
mod site chr3:119876456-119876457:- [13]
Sequence GAGAAATGAACCCAAACTACACAGAATTTAAATTCCCTCAA
Motif Score 2.084928571
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000264235.12; ENST00000316626.5; ENST00000473886.1; ENST00000650344.1
External Link RMBase: m6A_site_604709
mod ID: M6ASITE062255 Click to Show/Hide the Full List
mod site chr3:119876467-119876468:- [13]
Sequence GGAGCAAATCAGAGAAATGAACCCAAACTACACAGAATTTA
Motif Score 2.930744048
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000316626.5; ENST00000264235.12; ENST00000650344.1; ENST00000473886.1
External Link RMBase: m6A_site_604710
mod ID: M6ASITE062256 Click to Show/Hide the Full List
mod site chr3:119876492-119876493:- [12]
Sequence TCTAGGTCCTGGGAACTCCAACAAGGGAGCAAATCAGAGAA
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000650344.1; ENST00000316626.5; ENST00000473886.1; ENST00000264235.12
External Link RMBase: m6A_site_604711
mod ID: M6ASITE062257 Click to Show/Hide the Full List
mod site chr3:119905808-119905809:- [13]
Sequence TTGGCTGAGCTGTTACTAGGACAACCAATATTTCCAGGGGA
Motif Score 3.643047619
Cell/Tissue List HEK293T; hESC-HEK293T
Seq Type List DART-seq; MAZTER-seq
Transcript ID List ENST00000264235.12; ENST00000316626.5; ENST00000650344.1
External Link RMBase: m6A_site_604712
mod ID: M6ASITE062258 Click to Show/Hide the Full List
mod site chr3:119912756-119912757:- [13]
Sequence TTCGTATATCTGTTCTCGGTACTATAGGGCACCAGAGTTGA
Motif Score 3.278136905
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000264235.12; ENST00000650344.1; ENST00000316626.5
External Link RMBase: m6A_site_604713
mod ID: M6ASITE062259 Click to Show/Hide the Full List
mod site chr3:119916052-119916053:- [13]
Sequence TGCTGTATTAAAACTCTGTGACTTTGGAAGGTAAGCTACTG
Motif Score 3.28175
Cell/Tissue List HEK293T
Seq Type List DART-seq
Transcript ID List ENST00000650344.1; ENST00000264235.12; ENST00000316626.5
External Link RMBase: m6A_site_604714
mod ID: M6ASITE062260 Click to Show/Hide the Full List
mod site chr3:119916060-119916061:- [11]
Sequence CCTGATACTGCTGTATTAAAACTCTGTGACTTTGGAAGGTA
Motif Score 2.627720238
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12; ENST00000316626.5; ENST00000650344.1
External Link RMBase: m6A_site_604715
mod ID: M6ASITE062261 Click to Show/Hide the Full List
mod site chr3:119916094-119916095:- [11]
Sequence TCGGGATATTAAACCGCAGAACCTCTTGTTGGATCCTGATA
Motif Score 2.930744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12; ENST00000650344.1; ENST00000316626.5
External Link RMBase: m6A_site_604716
mod ID: M6ASITE062262 Click to Show/Hide the Full List
mod site chr3:119916102-119916103:- [11]
Sequence ATCTGCCATCGGGATATTAAACCGCAGAACCTCTTGTTGGA
Motif Score 2.185083333
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000316626.5; ENST00000650344.1; ENST00000264235.12
External Link RMBase: m6A_site_604717
mod ID: M6ASITE062263 Click to Show/Hide the Full List
mod site chr3:119923399-119923400:- [11]
Sequence AGACACTATAGTCGAGCCAAACAGACGCTCCCTGTGATTTA
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000650344.1; ENST00000316626.5; ENST00000264235.12
External Link RMBase: m6A_site_604718
mod ID: M6ASITE062264 Click to Show/Hide the Full List
mod site chr3:119923417-119923418:- [11]
Sequence ACAGTATACAGAGTTGCCAGACACTATAGTCGAGCCAAACA
Motif Score 2.897386905
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000650344.1; ENST00000264235.12; ENST00000316626.5
External Link RMBase: m6A_site_604719
mod ID: M6ASITE062265 Click to Show/Hide the Full List
mod site chr3:119923437-119923438:- [11]
Sequence TGCTGGACTATGTTCCGGAAACAGTATACAGAGTTGCCAGA
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000650344.1; ENST00000316626.5; ENST00000264235.12
External Link RMBase: m6A_site_604720
mod ID: M6ASITE062266 Click to Show/Hide the Full List
mod site chr3:119923451-119923452:- [11]
Sequence CTATCTTAATCTGGTGCTGGACTATGTTCCGGAAACAGTAT
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12; ENST00000316626.5; ENST00000650344.1
External Link RMBase: m6A_site_604721
mod ID: M6ASITE062267 Click to Show/Hide the Full List
mod site chr3:119947310-119947311:- [12]
Sequence GAGAAAGCTAGATCACTGTAACATAGTCCGATTGCGTTATT
Motif Score 2.168095238
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000316626.5; ENST00000264235.12; ENST00000650344.1
External Link RMBase: m6A_site_604722
mod ID: M6ASITE062268 Click to Show/Hide the Full List
mod site chr3:120002058-120002059:- [11]
Sequence CATCAAGAAAGTATTGCAGGACAAGAGATTTAAGGTAAAAT
Motif Score 3.643047619
Cell/Tissue List HeLa; hESC-HEK293T
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000650344.1; ENST00000316626.5; ENST00000264235.12
External Link RMBase: m6A_site_604723
mod ID: M6ASITE062269 Click to Show/Hide the Full List
mod site chr3:120002087-120002088:- [11]
Sequence AAACTTTGTGATTCAGGAGAACTGGTCGCCATCAAGAAAGT
Motif Score 3.373380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000316626.5; ENST00000264235.12; ENST00000650344.1
External Link RMBase: m6A_site_604724
mod ID: M6ASITE062270 Click to Show/Hide the Full List
mod site chr3:120002105-120002106:- [11]
Sequence GGTGTGGTATATCAAGCCAAACTTTGTGATTCAGGAGAACT
Motif Score 2.627720238
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000316626.5; ENST00000650344.1; ENST00000264235.12
External Link RMBase: m6A_site_604725
mod ID: M6ASITE062271 Click to Show/Hide the Full List
mod site chr3:120002154-120002155:- [11]
Sequence ACAAGAAGTCAGCTATACAGACACTAAAGTGATTGGAAATG
Motif Score 2.897386905
Cell/Tissue List HeLa; hESC-HEK293T; MM6; Jurkat; peripheral-blood; endometrial; NB4
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000316626.5; ENST00000650344.1; ENST00000264235.12
External Link RMBase: m6A_site_604726
mod ID: M6ASITE062272 Click to Show/Hide the Full List
mod site chr3:120002181-120002182:- [11]
Sequence AACTCCTGGGCAGGGTCCAGACAGGCCACAAGAAGTCAGCT
Motif Score 2.897386905
Cell/Tissue List HeLa; HepG2; MM6; Jurkat; CD4T; peripheral-blood; endometrial; HEC-1-A; NB4
Seq Type List m6A-seq
Transcript ID List ENST00000264235.12; ENST00000650344.1; ENST00000316626.5
External Link RMBase: m6A_site_604727
mod ID: M6ASITE062273 Click to Show/Hide the Full List
mod site chr3:120002235-120002236:- [11]
Sequence TTCCTTTCTTCCTTTAGGAGACAAGGACGGCAGCAAGGTGA
Motif Score 2.897386905
Cell/Tissue List HeLa; HepG2; hESC-HEK293T; LCLs; MM6; Jurkat; CD4T; peripheral-blood; endometrial; HEC-1-A; NB4
Seq Type List m6A-seq; MAZTER-seq
Transcript ID List ENST00000264235.12; ENST00000650344.1; ENST00000316626.5
External Link RMBase: m6A_site_604728
mod ID: M6ASITE062274 Click to Show/Hide the Full List
mod site chr3:120093415-120093416:- [11]
Sequence TCATGTCAGGGCGGCCCAGAACCACCTCCTTTGCGGAGAGC
Motif Score 2.930744048
Cell/Tissue List HeLa; HepG2; HEK293T; hNPCs; fibroblasts; LCLs; MM6; Jurkat; CD4T; peripheral-blood; endometrial; HEC-1-A; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000316626.5; ENST00000650344.1; ENST00000264235.12
External Link RMBase: m6A_site_604730
mod ID: M6ASITE062275 Click to Show/Hide the Full List
mod site chr3:120093488-120093489:- [11]
Sequence CCTAACACCCCAACATAAAGACAAAAGGAAGAAAAGGAGGA
Motif Score 2.897386905
Cell/Tissue List HeLa; HEK293T; hESC-HEK293T; hNPCs; fibroblasts; A549; LCLs; MT4; MM6; Jurkat; iSLK
Seq Type List m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List ENST00000316626.5; ENST00000264235.12; ENST00000650344.1
External Link RMBase: m6A_site_604731
mod ID: M6ASITE062276 Click to Show/Hide the Full List
mod site chr3:120093504-120093505:- [12]
Sequence CTGCATTTATCGTTAACCTAACACCCCAACATAAAGACAAA
Motif Score 2.168095238
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000316626.5; ENST00000650344.1; ENST00000264235.12
External Link RMBase: m6A_site_604732
mod ID: M6ASITE062277 Click to Show/Hide the Full List
mod site chr3:120093532-120093533:- [11]
Sequence TCTTTTTCTTCTGTGGGAGAACTTAATGCTGCATTTATCGT
Motif Score 3.373380952
Cell/Tissue List HeLa; HEK293T; hNPCs; fibroblasts; A549; LCLs; MT4; iSLK
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000650344.1; ENST00000264235.12; ENST00000316626.5
External Link RMBase: m6A_site_604733
mod ID: M6ASITE062278 Click to Show/Hide the Full List
mod site chr3:120093589-120093590:- [12]
Sequence TGTTTTGTTTTTTATAGTATACAAAAGGAGTGAAAAGCCAA
Motif Score 2.110482143
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000264235.12; ENST00000650344.1; ENST00000316626.5
External Link RMBase: m6A_site_604734
mod ID: M6ASITE062279 Click to Show/Hide the Full List
mod site chr3:120093831-120093832:- [17]
Sequence GCCGCTTCCCTTCTTCATTGACTCGGAAAAAAAATCCCCGA
Motif Score 3.28175
Cell/Tissue List CD8T
Seq Type List m6A-CLIP/IP
Transcript ID List ENST00000264235.12; ENST00000650344.1
External Link RMBase: m6A_site_604735
mod ID: M6ASITE062280 Click to Show/Hide the Full List
mod site chr3:120093866-120093867:- [11]
Sequence CCTTTCTCTTCAAGCGTGAGACTCGTGATCCTTCCGCCGCT
Motif Score 3.319380952
Cell/Tissue List HeLa; HepG2; HEK293T; A549; U2OS; H1B; hESCs; fibroblasts; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; HEC-1-A; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000264235.12; ENST00000650344.1
External Link RMBase: m6A_site_604736
mod ID: M6ASITE062281 Click to Show/Hide the Full List
mod site chr3:120094168-120094169:- [11]
Sequence ATGTCCCCGGCGAATGGGGAACAGTCGAGGAGCCGCTGCCT
Motif Score 2.951386905
Cell/Tissue List HeLa; CD34; HepG2; A549; HEK293T; U2OS; H1A; H1B; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; TREX; MSC; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604737
mod ID: M6ASITE062282 Click to Show/Hide the Full List
mod site chr3:120094297-120094298:- [11]
Sequence TGGGCTGGGGCAAAGCGCGGACACTTCCTGAGCGGGCACCG
Motif Score 3.643047619
Cell/Tissue List HeLa; CD34; HepG2; A549; HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; MT4; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List m6A-seq; MeRIP-seq
Transcript ID List ENST00000264235.12
External Link RMBase: m6A_site_604738
Pseudouridine (Pseudo)
In total 1 m6A sequence/site(s) in this target gene
mod ID: PSESITE000189 Click to Show/Hide the Full List
mod site chr3:120093530-120093531:- [18]
Sequence TTTTTCTTCTGTGGGAGAACTTAATGCTGCATTTATCGTTA
Transcript ID List ENST00000650344.1; ENST00000264235.12; ENST00000316626.5
External Link RMBase: Pseudo_site_3581