m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00220)
Target Name Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1B)
Synonyms
CPT1-M; Carnitine O-palmitoyltransferase I, muscle isoform; CPT I; CPTI-M; Carnitine palmitoyltransferase 1B; Carnitine palmitoyltransferase I-like protein; KIAA1670
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Gene Name CPT1B
Chromosomal Location 22q13.33
Family carnitine/choline acetyltransferase family
Function
Catalyzes the transfer of the acyl group of long-chain fatty acid-CoA conjugates onto carnitine, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion.
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Gene ID 1375
Uniprot ID
CPT1B_HUMAN
HGNC ID
HGNC:2329
KEGG ID
hsa:1375
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
CPT1B can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Disease
Solid tumour/cancer [ICD-11: 2A00-2F9Z]
 Disease Info 
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response []
Response Summary m6A induced ERR-Gamma confers chemoresistance of cancer cells through upregulation of ABCB1 and Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1B).
Responsed Disease Solid tumour/cancer [ICD-11: 2A00-2F9Z]
Pathway Response ABC transporters hsa02010
Fatty acid metabolism hsa01212
Fatty acid degradation hsa00071
Cell Process Fatty acid oxidation
In-vitro Model ()
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In-vivo Model Both sh-control and sh- ERRγ HepG2/ADR cells (5 × 106 per mouse, n=5 for each group) were diluted in 200uL PBS + 200 uL Matrigel (BD Biosciences) and subcutaneously injected into immunodeficient mice.
RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00220)
Carnitine O-palmitoyltransferase 1, muscle isoform (CPT1B)
5-methylcytidine (m5C)
In total 3 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002974 Click to Show/Hide the Full List
mod site chr22:50572914-50572915:-
Sequence AAGATGAGGCCAGCCTCAGCCTCTATGGCAAGGCCCTGCTA
Cell/Tissue List testis
Seq Type List Bisulfite-seq
Transcript ID List ENST00000405237.7; ENST00000457250.5; ENST00000475238.1; ENST00000423069.1; ENST00000312108.11; ENST00000492556.5; ENST00000395650.6; ENST00000360719.6; ENST00000453634.5
External Link RMBase: m5C_site_31430
mod ID: M5CSITE002975 Click to Show/Hide the Full List
mod site chr22:50576979-50576980:-
Sequence CTTCTCAGCATGGCCATCTTCTCCACGGGCGTCTGGGTGAC
Cell/Tissue List testis
Seq Type List Bisulfite-seq
Transcript ID List ENST00000453634.5; ENST00000460853.1; ENST00000360719.6; ENST00000461117.1; ENST00000417176.1; ENST00000312108.11; ENST00000492556.5; ENST00000457250.5; ENST00000395650.6; ENST00000405237.7
External Link RMBase: m5C_site_31431
mod ID: M5CSITE002976 Click to Show/Hide the Full List
mod site chr22:50577327-50577328:-
Sequence GCATCCAGAGATGCCTCCCTCAGGGGTAAGGAGTGAAACTG
Cell/Tissue List testis
Seq Type List Bisulfite-seq
Transcript ID List ENST00000460853.1; ENST00000457250.5; ENST00000492556.5; ENST00000395650.6; ENST00000417176.1; ENST00000453634.5; ENST00000360719.6; ENST00000461117.1; ENST00000405237.7; ENST00000312108.11
External Link RMBase: m5C_site_31432
N6-methyladenosine (m6A)
In total 35 m6A sequence/site(s) in this target gene
mod ID: M6ASITE059205 Click to Show/Hide the Full List
mod site chr22:50568970-50568971:- [1]
Sequence TGGAAGACTGTTCATGAGGGACTTGTGTGACCTGCTTTGAA
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000312108.11; ENST00000405237.7; ENST00000492556.5
External Link RMBase: m6A_site_574220
mod ID: M6ASITE059206 Click to Show/Hide the Full List
mod site chr22:50568984-50568985:- [1]
Sequence AGAAGGGCTGAAGCTGGAAGACTGTTCATGAGGGACTTGTG
Motif Score 3.319380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000312108.11; ENST00000405237.7; ENST00000492556.5
External Link RMBase: m6A_site_574221
mod ID: M6ASITE059207 Click to Show/Hide the Full List
mod site chr22:50569021-50569022:- [1]
Sequence CTCCCCCTCCCCCAGCTCAGACCACAGAGGTGGCAAGAGAA
Motif Score 2.876744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000453634.5; ENST00000492556.5; ENST00000312108.11; ENST00000405237.7
External Link RMBase: m6A_site_574222
mod ID: M6ASITE059208 Click to Show/Hide the Full List
mod site chr22:50569398-50569399:- [2]
Sequence CGCCCAGCGCTTTGGAAACCACATCCGCAAAGCCCTGCTGG
Motif Score 2.053113095
Cell/Tissue List brain; kidney
Seq Type List m6A-REF-seq
Transcript ID List ENST00000360719.6; ENST00000457250.5; ENST00000453634.5; ENST00000395650.6; ENST00000405237.7; ENST00000492556.5; ENST00000312108.11
External Link RMBase: m6A_site_574223
mod ID: M6ASITE059209 Click to Show/Hide the Full List
mod site chr22:50571035-50571036:- [3]
Sequence TTCTGCCCCGCAGAAAGCAGACCTGCGAGATCTCTTCCAGA
Motif Score 2.876744048
Cell/Tissue List HeLa
Seq Type List MeRIP-seq
Transcript ID List ENST00000453634.5; ENST00000497224.1; ENST00000492556.5; ENST00000395650.6; ENST00000405237.7; ENST00000457250.5; ENST00000312108.11; ENST00000360719.6
External Link RMBase: m6A_site_574224
mod ID: M6ASITE059210 Click to Show/Hide the Full List
mod site chr22:50571195-50571196:- [2]
Sequence GTTCCTGTACCAGCGAGTCCACAGCCTTTGTGCAGGCCATG
Motif Score 2.053113095
Cell/Tissue List kidney
Seq Type List m6A-REF-seq
Transcript ID List ENST00000312108.11; ENST00000453634.5; ENST00000405237.7; ENST00000395650.6; ENST00000457250.5; ENST00000497224.1; ENST00000360719.6; ENST00000492556.5
External Link RMBase: m6A_site_574225
mod ID: M6ASITE059211 Click to Show/Hide the Full List
mod site chr22:50571222-50571223:- [3]
Sequence TCCGGGAGGGACGGACTGAGACTGTGCGTTCCTGTACCAGC
Motif Score 3.319380952
Cell/Tissue List HeLa
Seq Type List MeRIP-seq
Transcript ID List ENST00000405237.7; ENST00000395650.6; ENST00000453634.5; ENST00000492556.5; ENST00000457250.5; ENST00000360719.6; ENST00000312108.11; ENST00000497224.1
External Link RMBase: m6A_site_574226
mod ID: M6ASITE059212 Click to Show/Hide the Full List
mod site chr22:50571228-50571229:- [3]
Sequence GAATGTTCCGGGAGGGACGGACTGAGACTGTGCGTTCCTGT
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List MeRIP-seq
Transcript ID List ENST00000405237.7; ENST00000457250.5; ENST00000497224.1; ENST00000312108.11; ENST00000360719.6; ENST00000453634.5; ENST00000492556.5; ENST00000395650.6
External Link RMBase: m6A_site_574227
mod ID: M6ASITE059213 Click to Show/Hide the Full List
mod site chr22:50571290-50571291:- [3]
Sequence ACCCCTCTGTATATCCCAGGACAGGGGTAAGTTCTGCCTGA
Motif Score 3.643047619
Cell/Tissue List HeLa
Seq Type List MeRIP-seq
Transcript ID List ENST00000497224.1; ENST00000360719.6; ENST00000312108.11; ENST00000457250.5; ENST00000453634.5; ENST00000405237.7; ENST00000492556.5; ENST00000395650.6
External Link RMBase: m6A_site_574228
mod ID: M6ASITE059214 Click to Show/Hide the Full List
mod site chr22:50571424-50571425:- [3]
Sequence GCCTCATCAAGAAGTGCCGGACCAGCCCTGATGCCTTTGTG
Motif Score 3.622404762
Cell/Tissue List HeLa
Seq Type List MeRIP-seq
Transcript ID List ENST00000453634.5; ENST00000312108.11; ENST00000395650.6; ENST00000492556.5; ENST00000457250.5; ENST00000360719.6; ENST00000497224.1; ENST00000405237.7
External Link RMBase: m6A_site_574229
mod ID: M6ASITE059215 Click to Show/Hide the Full List
mod site chr22:50572008-50572009:- [1]
Sequence CTGCAGTGGGACATTCCAAAACAGGTGGGTTGGAAGCTCCC
Motif Score 2.20572619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000457250.5; ENST00000492556.5; ENST00000453634.5; ENST00000497224.1; ENST00000405237.7; ENST00000395650.6; ENST00000475238.1; ENST00000360719.6; ENST00000312108.11
External Link RMBase: m6A_site_574230
mod ID: M6ASITE059216 Click to Show/Hide the Full List
mod site chr22:50572018-50572019:- [1]
Sequence TCCTACACGGCTGCAGTGGGACATTCCAAAACAGGTGGGTT
Motif Score 3.643047619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000492556.5; ENST00000457250.5; ENST00000405237.7; ENST00000395650.6; ENST00000497224.1; ENST00000453634.5; ENST00000360719.6; ENST00000312108.11; ENST00000475238.1
External Link RMBase: m6A_site_574231
mod ID: M6ASITE059217 Click to Show/Hide the Full List
mod site chr22:50572054-50572055:- [1]
Sequence GCACTGCCTGGGCAAACCGAACCCTGCGCTCGCACCTCCTA
Motif Score 2.930744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000492556.5; ENST00000457250.5; ENST00000360719.6; ENST00000405237.7; ENST00000497224.1; ENST00000312108.11; ENST00000395650.6; ENST00000475238.1; ENST00000453634.5
External Link RMBase: m6A_site_574232
mod ID: M6ASITE059218 Click to Show/Hide the Full List
mod site chr22:50572059-50572060:- [1]
Sequence ACCGGGCACTGCCTGGGCAAACCGAACCCTGCGCTCGCACC
Motif Score 2.185083333
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000405237.7; ENST00000475238.1; ENST00000360719.6; ENST00000395650.6; ENST00000457250.5; ENST00000453634.5; ENST00000492556.5; ENST00000497224.1; ENST00000312108.11
External Link RMBase: m6A_site_574233
mod ID: M6ASITE059219 Click to Show/Hide the Full List
mod site chr22:50572079-50572080:- [1]
Sequence TCCACCTGGGCTACACGGAGACCGGGCACTGCCTGGGCAAA
Motif Score 2.876744048
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000475238.1; ENST00000360719.6; ENST00000457250.5; ENST00000312108.11; ENST00000497224.1; ENST00000395650.6; ENST00000453634.5; ENST00000405237.7; ENST00000492556.5
External Link RMBase: m6A_site_574234
mod ID: M6ASITE059220 Click to Show/Hide the Full List
mod site chr22:50573693-50573694:- [4]
Sequence TGTGCTACAGCACCTCTCAGACAGCCGGCACGTGGCTGTCT
Motif Score 2.897386905
Cell/Tissue List MT4; peripheral-blood
Seq Type List MeRIP-seq; m6A-seq
Transcript ID List ENST00000492556.5; ENST00000395650.6; ENST00000457250.5; ENST00000453634.5; ENST00000312108.11; ENST00000405237.7; ENST00000360719.6; ENST00000423069.1
External Link RMBase: m6A_site_574235
mod ID: M6ASITE059221 Click to Show/Hide the Full List
mod site chr22:50573811-50573812:- [4]
Sequence CCAGGCAGAGGCCGAGCAAAACAGGGTCTGCAGGGGTCACC
Motif Score 2.20572619
Cell/Tissue List MT4; peripheral-blood
Seq Type List MeRIP-seq; m6A-seq
Transcript ID List ENST00000453634.5; ENST00000360719.6; ENST00000457250.5; ENST00000492556.5; ENST00000405237.7; ENST00000423069.1; ENST00000395650.6; ENST00000312108.11
External Link RMBase: m6A_site_574236
mod ID: M6ASITE059222 Click to Show/Hide the Full List
mod site chr22:50573863-50573864:- [4]
Sequence AGCACAGGGCCTGGTTTAGGACACACGGATCCCATCCAGGG
Motif Score 3.643047619
Cell/Tissue List MT4
Seq Type List MeRIP-seq
Transcript ID List ENST00000453634.5; ENST00000423069.1; ENST00000492556.5; ENST00000395650.6; ENST00000457250.5; ENST00000312108.11; ENST00000405237.7; ENST00000360719.6
External Link RMBase: m6A_site_574237
mod ID: M6ASITE059223 Click to Show/Hide the Full List
mod site chr22:50574339-50574340:- [4]
Sequence CACTCGGATCCCGGGCAAGGACACAGGTAACTGAGCCCCCT
Motif Score 3.643047619
Cell/Tissue List MT4; peripheral-blood
Seq Type List MeRIP-seq; m6A-seq
Transcript ID List ENST00000492556.5; ENST00000453634.5; ENST00000395650.6; ENST00000360719.6; ENST00000457250.5; ENST00000405237.7; ENST00000312108.11; ENST00000423069.1
External Link RMBase: m6A_site_574238
mod ID: M6ASITE059224 Click to Show/Hide the Full List
mod site chr22:50574363-50574364:- [5]
Sequence CCAGATGGAGAGGATGTTCAACACCACTCGGATCCCGGGCA
Motif Score 2.173910714
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000492556.5; ENST00000457250.5; ENST00000405237.7; ENST00000453634.5; ENST00000312108.11; ENST00000360719.6; ENST00000423069.1; ENST00000395650.6
External Link RMBase: m6A_site_574239
mod ID: M6ASITE059225 Click to Show/Hide the Full List
mod site chr22:50574511-50574512:- [4]
Sequence CATGTATCGCCGTAAACTGGACCGTGAAGAAATCAAGCCTG
Motif Score 3.622404762
Cell/Tissue List MT4
Seq Type List MeRIP-seq
Transcript ID List ENST00000453634.5; ENST00000395650.6; ENST00000423069.1; ENST00000312108.11; ENST00000360719.6; ENST00000492556.5; ENST00000479886.1; ENST00000405237.7; ENST00000457250.5
External Link RMBase: m6A_site_574240
mod ID: M6ASITE059226 Click to Show/Hide the Full List
mod site chr22:50574516-50574517:- [4]
Sequence ATGATCATGTATCGCCGTAAACTGGACCGTGAAGAAATCAA
Motif Score 2.627720238
Cell/Tissue List MT4
Seq Type List MeRIP-seq
Transcript ID List ENST00000457250.5; ENST00000453634.5; ENST00000405237.7; ENST00000492556.5; ENST00000312108.11; ENST00000360719.6; ENST00000395650.6; ENST00000423069.1; ENST00000479886.1
External Link RMBase: m6A_site_574241
mod ID: M6ASITE059227 Click to Show/Hide the Full List
mod site chr22:50574550-50574551:- [4]
Sequence GCAGGCAGCCCGCCTGGGAAACATCATCCACGCCATGATCA
Motif Score 2.20572619
Cell/Tissue List MT4
Seq Type List MeRIP-seq
Transcript ID List ENST00000360719.6; ENST00000492556.5; ENST00000457250.5; ENST00000312108.11; ENST00000395650.6; ENST00000405237.7; ENST00000479886.1; ENST00000423069.1; ENST00000453634.5
External Link RMBase: m6A_site_574242
mod ID: M6ASITE059228 Click to Show/Hide the Full List
mod site chr22:50576089-50576090:- [5]
Sequence GAGTGACTGGTGGGAAGAGTACATCTACCTTCGAGGCAGGA
Motif Score 2.856142857
Cell/Tissue List hESC-HEK293T
Seq Type List MAZTER-seq
Transcript ID List ENST00000492556.5; ENST00000476790.1; ENST00000405237.7; ENST00000360719.6; rmsk_5316824; ENST00000395650.6; ENST00000457250.5; ENST00000453634.5; ENST00000312108.11
External Link RMBase: m6A_site_574243
mod ID: M6ASITE059229 Click to Show/Hide the Full List
mod site chr22:50576253-50576254:- [1]
Sequence CCAAAGAATTCCAGGACAAGACTGCCCCCAGGCTGCAGAAA
Motif Score 3.319380952
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000395650.6; ENST00000476790.1; ENST00000457250.5; ENST00000405237.7; ENST00000453634.5; ENST00000492556.5; ENST00000312108.11; ENST00000360719.6
External Link RMBase: m6A_site_574244
mod ID: M6ASITE059230 Click to Show/Hide the Full List
mod site chr22:50576258-50576259:- [1]
Sequence GCTGGCCAAAGAATTCCAGGACAAGACTGCCCCCAGGCTGC
Motif Score 3.643047619
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000492556.5; ENST00000453634.5; ENST00000395650.6; ENST00000360719.6; ENST00000457250.5; ENST00000476790.1; ENST00000405237.7; ENST00000312108.11
External Link RMBase: m6A_site_574245
mod ID: M6ASITE059231 Click to Show/Hide the Full List
mod site chr22:50576768-50576769:- [6]
Sequence GAGCTAGACGGGAGAGGCAGACAGGGCACTGGTGCCTGGTG
Motif Score 2.897386905
Cell/Tissue List HEK293A-TOA
Seq Type List m6A-seq
Transcript ID List ENST00000360719.6; ENST00000405237.7; ENST00000457250.5; ENST00000460853.1; ENST00000395650.6; ENST00000476790.1; ENST00000461117.1; ENST00000312108.11; ENST00000453634.5; ENST00000492556.5
External Link RMBase: m6A_site_574246
mod ID: M6ASITE059232 Click to Show/Hide the Full List
mod site chr22:50576804-50576805:- [6]
Sequence CCTGGGTTGAGACTCTTTGGACTCCTTTGGGGTTCTGAGCT
Motif Score 4.065041667
Cell/Tissue List HEK293A-TOA
Seq Type List m6A-seq
Transcript ID List ENST00000461117.1; ENST00000405237.7; ENST00000457250.5; ENST00000492556.5; ENST00000476790.1; ENST00000453634.5; ENST00000395650.6; ENST00000312108.11; ENST00000460853.1; ENST00000360719.6
External Link RMBase: m6A_site_574247
mod ID: M6ASITE059233 Click to Show/Hide the Full List
mod site chr22:50576813-50576814:- [6]
Sequence GTTCAGGCACCTGGGTTGAGACTCTTTGGACTCCTTTGGGG
Motif Score 3.319380952
Cell/Tissue List HEK293A-TOA
Seq Type List m6A-seq
Transcript ID List ENST00000360719.6; ENST00000453634.5; ENST00000460853.1; ENST00000461117.1; ENST00000405237.7; ENST00000395650.6; ENST00000492556.5; ENST00000457250.5; ENST00000312108.11; ENST00000476790.1
External Link RMBase: m6A_site_574248
mod ID: M6ASITE059234 Click to Show/Hide the Full List
mod site chr22:50576882-50576883:- [1]
Sequence TGTTTGAGATGCATGGCAAGACCAGCAACTTGACCAGGATC
Motif Score 2.876744048
Cell/Tissue List HeLa; HEK293A-TOA
Seq Type List m6A-seq
Transcript ID List ENST00000457250.5; ENST00000476790.1; ENST00000492556.5; ENST00000312108.11; ENST00000453634.5; ENST00000460853.1; ENST00000461117.1; ENST00000360719.6; ENST00000395650.6; ENST00000405237.7
External Link RMBase: m6A_site_574249
mod ID: M6ASITE059235 Click to Show/Hide the Full List
mod site chr22:50576936-50576937:- [1]
Sequence GCATCTTCTTCTTCCGCCAAACCCTGAAGCTGCTTCTCTGC
Motif Score 2.185083333
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000360719.6; ENST00000492556.5; ENST00000460853.1; ENST00000312108.11; ENST00000453634.5; ENST00000457250.5; ENST00000405237.7; ENST00000461117.1; ENST00000395650.6
External Link RMBase: m6A_site_574250
mod ID: M6ASITE059236 Click to Show/Hide the Full List
mod site chr22:50578012-50578013:- [1]
Sequence GGGGGCGCGAGGGGTCGCGGACTGGCTGGGGGCGTCTCGGC
Motif Score 4.065041667
Cell/Tissue List HeLa
Seq Type List m6A-seq
Transcript ID List ENST00000452668.1; ENST00000417176.1; ENST00000395650.6; ENST00000405237.7; ENST00000312108.11; ENST00000492556.5; ENST00000460853.1; ENST00000453634.5
External Link RMBase: m6A_site_574251
mod ID: M6ASITE059237 Click to Show/Hide the Full List
mod site chr22:50578393-50578394:- [7]
Sequence CCACGCACGGACAGGAGTGAACCCGAGCTGTGAGTAGGGGC
Motif Score 2.930744048
Cell/Tissue List HEK293T
Seq Type List m6A-seq
Transcript ID List ENST00000312108.11; ENST00000492556.5; ENST00000460853.1; ENST00000395650.6; ENST00000453634.5; ENST00000452668.1
External Link RMBase: m6A_site_574252
mod ID: M6ASITE059238 Click to Show/Hide the Full List
mod site chr22:50578403-50578404:- [7]
Sequence GTGGCTGGCCCCACGCACGGACAGGAGTGAACCCGAGCTGT
Motif Score 3.643047619
Cell/Tissue List HEK293T
Seq Type List m6A-seq
Transcript ID List ENST00000460853.1; ENST00000395650.6; ENST00000492556.5; ENST00000453634.5; ENST00000312108.11; ENST00000452668.1
External Link RMBase: m6A_site_574253
mod ID: M6ASITE059239 Click to Show/Hide the Full List
mod site chr22:50578435-50578436:- [7]
Sequence TAGGCCTGAAGGACGTGGGGACACGGGCCAGAGTGGCTGGC
Motif Score 3.643047619
Cell/Tissue List HEK293T
Seq Type List m6A-seq
Transcript ID List ENST00000452668.1; ENST00000460853.1; ENST00000453634.5; ENST00000492556.5; ENST00000395650.6
External Link RMBase: m6A_site_574254