m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00162)

Target Name	Neutral amino acid transporter B(0) (SLC1A5)
Synonyms	ATB(0); Baboon M7 virus receptor; RD114/simian type D retrovirus receptor; Sodium-dependent neutral amino acid transporter type 2; Solute carrier family 1 member 5; ASCT2; M7V1; RDR; RDRC Click to Show/Hide
Gene Name	SLC1A5
Chromosomal Location	19q13.32
Family	dicarboxylate/amino acid:cation symporter (DAACS) (TC 2;A;23) family; SLC1A5 subfamily
Function	Sodium-dependent amino acids transporter that has a broad substrate specificity, with a preference for zwitterionic amino acids. It accepts as substrates all neutral amino acids, including glutamine, asparagine, and branched-chain and aromatic amino acids, and excludes methylated, anionic, and cationic amino acids. Through binding of the fusogenic protein syncytin-1/ERVW-1 may mediate trophoblasts syncytialization, the spontaneous fusion of their plasma membranes, an essential process in placental development. (Microbial infection) Acts as a cell surface receptor for Feline endogenous virus RD114. (Microbial infection) Acts as a cell surface receptor for Baboon M7 endogenous virus. (Microbial infection) Acts as a cell surface receptor for type D simian retroviruses. Click to Show/Hide
Gene ID	6510
Uniprot ID	AAAT_HUMAN
HGNC ID	HGNC:10943
KEGG ID	hsa:6510

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

SLC1A5 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

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Fat mass and obesity-associated protein (FTO) [ERASER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by FTO*
Cell Line	253J cell line	Homo sapiens
Treatment: siFTO 253J cells Control: 253J cells		GSE150239
Regulation		logFC: -1.02E+00 p-value: 5.80E-30
More Results	Click to View More RNA-seq Results

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene			[1]
Response Summary	Genetic inactivation of FTO using multiple orthogonal approaches revealed that FTO inhibition selectively reduces the growth and survival of VHL-deficient cells in vitro and in vivo. Integrated analysis of transcriptome-wide m6A-seq and mRNA-seq analysis identified the glutamine transporter Neutral amino acid transporter B(0) (SLC1A5) as an FTO target that promotes metabolic reprogramming and survival of VHL-deficient ccRCC cells. GLS1 inhibitors that target mitochondrial glutaminase and the conversion of glutamine to glutamate are currently being evaluated in early-phase clinical trials in ccRCC. These findings identify FTO as a potential HIF-independent therapeutic target for the treatment of VHL-deficient renal cell carcinoma.
Target Regulation	Up regulation
Responsed Disease	Renal cell carcinoma	ICD-11: 2C90	Disease Info
Responsed Drug	GLS-IN-968	Investigative	Drug Info
Pathway Response	Central carbon metabolism in cancer		hsa05230
	HIF-1 signaling pathway		hsa04066
	Central carbon metabolism in cancer		hsa05230
	Metabolic pathways		hsa01100
	VEGF signaling pathway		hsa04370
In-vitro Model	UMRC2-vec (CCRCC isogenic cell lines that are VHL-deficient)

Renal cell carcinoma [ICD-11: 2C90]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response			[1]
Response Summary	Genetic inactivation of FTO using multiple orthogonal approaches revealed that FTO inhibition selectively reduces the growth and survival of VHL-deficient cells in vitro and in vivo. Integrated analysis of transcriptome-wide m6A-seq and mRNA-seq analysis identified the glutamine transporter Neutral amino acid transporter B(0) (SLC1A5) as an FTO target that promotes metabolic reprogramming and survival of VHL-deficient ccRCC cells. GLS1 inhibitors that target mitochondrial glutaminase and the conversion of glutamine to glutamate are currently being evaluated in early-phase clinical trials in ccRCC. These findings identify FTO as a potential HIF-independent therapeutic target for the treatment of VHL-deficient renal cell carcinoma.
Responsed Disease	Renal cell carcinoma [ICD-11: 2C90]
Target Regulator	Fat mass and obesity-associated protein (FTO)	ERASER	Regulator Info
Target Regulation	Up regulation
Responsed Drug	GLS-IN-968	Investigative	Drug Info
Pathway Response	Central carbon metabolism in cancer		hsa05230
	HIF-1 signaling pathway		hsa04066
	Central carbon metabolism in cancer		hsa05230
	Metabolic pathways		hsa01100
	VEGF signaling pathway		hsa04370
In-vitro Model	UMRC2-vec (CCRCC isogenic cell lines that are VHL-deficient)

GLS-IN-968 [Investigative]

Drug Info

In total 1 item(s) under this drug
Experiment 1 Reporting the m6A-centered Drug Response			[1]
Response Summary	Genetic inactivation of FTO using multiple orthogonal approaches revealed that FTO inhibition selectively reduces the growth and survival of VHL-deficient cells in vitro and in vivo. Integrated analysis of transcriptome-wide m6A-seq and mRNA-seq analysis identified the glutamine transporter Neutral amino acid transporter B(0) (SLC1A5) as an FTO target that promotes metabolic reprogramming and survival of VHL-deficient ccRCC cells. GLS1 inhibitors that target mitochondrial glutaminase and the conversion of glutamine to glutamate are currently being evaluated in early-phase clinical trials in ccRCC. These findings identify FTO as a potential HIF-independent therapeutic target for the treatment of VHL-deficient renal cell carcinoma.
Target Regulator	Fat mass and obesity-associated protein (FTO)	ERASER	Regulator Info
Target Regulation	Up regulation
Responsed Disease	Renal cell carcinoma	ICD-11: 2C90	Disease Info
Pathway Response	Central carbon metabolism in cancer		hsa05230
	HIF-1 signaling pathway		hsa04066
	Central carbon metabolism in cancer		hsa05230
	Metabolic pathways		hsa01100
	VEGF signaling pathway		hsa04370
In-vitro Model	UMRC2-vec (CCRCC isogenic cell lines that are VHL-deficient)

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00162)

Neutral amino acid transporter B(0) (SLC1A5)

N4-acetylcytidine (ac4C)

In total 2 m6A sequence/site(s) in this target gene
mod ID: AC4SITE000002		Click to Show/Hide the Full List
mod site	chr19:46775580-46775581:-
Sequence	TCCCCACTGAGGAAGGAAACCCCCTCCTCAAACACTATCGG
Cell/Tissue List	DLD1
Seq Type List	acRIP-seq
Transcript ID List	ENST00000412532.6; ENST00000542575.6; ENST00000594991.5; ENST00000434726.6
External Link	RMBase: ac4C_site_1025
mod ID: AC4SITE000003		Click to Show/Hide the Full List
mod site	chr19:46787551-46787552:-
Sequence	CTGCTCTTTTTCCTGGTCACCACGCTGCTGGCGTCGGCGCT
Cell/Tissue List	DLD1
Seq Type List	acRIP-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: ac4C_site_1026

Adenosine-to-Inosine editing (A-to-I)

In total 17 m6A sequence/site(s) in this target gene
mod ID: A2ISITE009243		Click to Show/Hide the Full List
mod site	chr19:46776375-46776376:-		[2]
Sequence	ATCTCCACTAAAAATACAAAAAAATTAGCCGGGTATGGTGG
Transcript ID List	ENST00000594991.5; ENST00000434726.6; ENST00000542575.6; rmsk_5014510; ENST00000412532.6
External Link	RMBase: RNA-editing_site_71360
mod ID: A2ISITE009244		Click to Show/Hide the Full List
mod site	chr19:46779984-46779985:-		[3]
Sequence	TAGCACGCGCCTATAGTCCCAGCTACTTGGGAGGCTGAGGC
Transcript ID List	ENST00000542575.6; ENST00000594991.5; ENST00000412532.6; ENST00000593713.1; ENST00000434726.6; rmsk_5014518
External Link	RMBase: RNA-editing_site_71361
mod ID: A2ISITE009245		Click to Show/Hide the Full List
mod site	chr19:46779992-46779993:-		[3]
Sequence	GGGCGTGGTAGCACGCGCCTATAGTCCCAGCTACTTGGGAG
Transcript ID List	ENST00000434726.6; ENST00000593713.1; ENST00000412532.6; ENST00000542575.6; ENST00000594991.5; rmsk_5014518
External Link	RMBase: RNA-editing_site_71362
mod ID: A2ISITE009246		Click to Show/Hide the Full List
mod site	chr19:46780000-46780001:-		[3]
Sequence	AATTAGCTGGGCGTGGTAGCACGCGCCTATAGTCCCAGCTA
Transcript ID List	ENST00000542575.6; ENST00000412532.6; ENST00000434726.6; rmsk_5014518; ENST00000593713.1; ENST00000594991.5
External Link	RMBase: RNA-editing_site_71363
mod ID: A2ISITE009247		Click to Show/Hide the Full List
mod site	chr19:46780003-46780004:-		[3]
Sequence	AAAAATTAGCTGGGCGTGGTAGCACGCGCCTATAGTCCCAG
Transcript ID List	ENST00000594991.5; ENST00000593713.1; ENST00000542575.6; rmsk_5014518; ENST00000412532.6; ENST00000434726.6
External Link	RMBase: RNA-editing_site_71364
mod ID: A2ISITE009248		Click to Show/Hide the Full List
mod site	chr19:46780016-46780017:-		[3]
Sequence	TACTAAAAATACAAAAAATTAGCTGGGCGTGGTAGCACGCG
Transcript ID List	ENST00000412532.6; ENST00000593713.1; ENST00000542575.6; ENST00000594991.5; ENST00000434726.6; rmsk_5014518
External Link	RMBase: RNA-editing_site_71365
mod ID: A2ISITE009249		Click to Show/Hide the Full List
mod site	chr19:46780048-46780049:-		[3]
Sequence	CCATCCTGGCTAACACAGAAAAACCCTGTCTCTACTAAAAA
Transcript ID List	ENST00000593713.1; ENST00000542575.6; rmsk_5014518; ENST00000434726.6; ENST00000594991.5; ENST00000412532.6
External Link	RMBase: RNA-editing_site_71366
mod ID: A2ISITE009250		Click to Show/Hide the Full List
mod site	chr19:46780049-46780050:-		[3]
Sequence	ACCATCCTGGCTAACACAGAAAAACCCTGTCTCTACTAAAA
Transcript ID List	ENST00000542575.6; ENST00000434726.6; ENST00000412532.6; rmsk_5014518; ENST00000594991.5; ENST00000593713.1
External Link	RMBase: RNA-editing_site_71367
mod ID: A2ISITE009251		Click to Show/Hide the Full List
mod site	chr19:46780052-46780053:-		[3]
Sequence	GAGACCATCCTGGCTAACACAGAAAAACCCTGTCTCTACTA
Transcript ID List	ENST00000542575.6; ENST00000594991.5; ENST00000412532.6; ENST00000593713.1; ENST00000434726.6; rmsk_5014518
External Link	RMBase: RNA-editing_site_71368
mod ID: A2ISITE009252		Click to Show/Hide the Full List
mod site	chr19:46780056-46780057:-		[3]
Sequence	GATCGAGACCATCCTGGCTAACACAGAAAAACCCTGTCTCT
Transcript ID List	ENST00000593713.1; ENST00000594991.5; ENST00000434726.6; rmsk_5014518; ENST00000542575.6; ENST00000412532.6
External Link	RMBase: RNA-editing_site_71369
mod ID: A2ISITE009253		Click to Show/Hide the Full List
mod site	chr19:46780080-46780081:-		[3]
Sequence	GGCAGGCAGATCACGAGGTCAGGAGATCGAGACCATCCTGG
Transcript ID List	ENST00000593713.1; rmsk_5014518; ENST00000434726.6; ENST00000412532.6; ENST00000594991.5; ENST00000542575.6
External Link	RMBase: RNA-editing_site_71370
mod ID: A2ISITE009254		Click to Show/Hide the Full List
mod site	chr19:46780093-46780094:-		[3]
Sequence	TTTGGGAGGCTGAGGCAGGCAGATCACGAGGTCAGGAGATC
Transcript ID List	rmsk_5014518; ENST00000434726.6; ENST00000412532.6; ENST00000542575.6; ENST00000593713.1; ENST00000594991.5
External Link	RMBase: RNA-editing_site_71371
mod ID: A2ISITE009255		Click to Show/Hide the Full List
mod site	chr19:46780097-46780098:-		[3]
Sequence	GCACTTTGGGAGGCTGAGGCAGGCAGATCACGAGGTCAGGA
Transcript ID List	ENST00000594991.5; ENST00000412532.6; ENST00000542575.6; rmsk_5014518; ENST00000593713.1; ENST00000434726.6
External Link	RMBase: RNA-editing_site_71372
mod ID: A2ISITE009256		Click to Show/Hide the Full List
mod site	chr19:46780101-46780102:-		[3]
Sequence	CCCAGCACTTTGGGAGGCTGAGGCAGGCAGATCACGAGGTC
Transcript ID List	ENST00000542575.6; ENST00000412532.6; ENST00000434726.6; rmsk_5014518; ENST00000593713.1; ENST00000594991.5
External Link	RMBase: RNA-editing_site_71373
mod ID: A2ISITE009257		Click to Show/Hide the Full List
mod site	chr19:46780126-46780127:-		[3]
Sequence	CAGTACGGAGGCTCATGCCTATAATCCCAGCACTTTGGGAG
Transcript ID List	ENST00000594991.5; ENST00000593713.1; ENST00000412532.6; rmsk_5014518; ENST00000542575.6; ENST00000434726.6
External Link	RMBase: RNA-editing_site_71374
mod ID: A2ISITE009258		Click to Show/Hide the Full List
mod site	chr19:46780145-46780146:-		[3]
Sequence	TTTAAGAAACTGGGTGGCCCAGTACGGAGGCTCATGCCTAT
Transcript ID List	rmsk_5014518; ENST00000594991.5; ENST00000542575.6; ENST00000434726.6; ENST00000412532.6; ENST00000593713.1
External Link	RMBase: RNA-editing_site_71375
mod ID: A2ISITE009259		Click to Show/Hide the Full List
mod site	chr19:46780577-46780578:-		[2]
Sequence	ATTGCTTGAGGCCAGGAGTTAGAGACTAGCCTGGTCAACAT
Transcript ID List	ENST00000542575.6; ENST00000412532.6; ENST00000594991.5; rmsk_5014520; ENST00000593713.1; ENST00000434726.6
External Link	RMBase: RNA-editing_site_71376

5-methylcytidine (m5C)

In total 8 m6A sequence/site(s) in this target gene
mod ID: M5CSITE002063		Click to Show/Hide the Full List
mod site	chr19:46775577-46775578:-		[4]
Sequence	CCACTGAGGAAGGAAACCCCCTCCTCAAACACTATCGGGGG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000594991.5; ENST00000542575.6; ENST00000434726.6; ENST00000412532.6
External Link	RMBase: m5C_site_25031
mod ID: M5CSITE002064		Click to Show/Hide the Full List
mod site	chr19:46775578-46775579:-		[4]
Sequence	CCCACTGAGGAAGGAAACCCCCTCCTCAAACACTATCGGGG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000434726.6; ENST00000594991.5; ENST00000412532.6; ENST00000542575.6
External Link	RMBase: m5C_site_25032
mod ID: M5CSITE002065		Click to Show/Hide the Full List
mod site	chr19:46775579-46775580:-		[4]
Sequence	CCCCACTGAGGAAGGAAACCCCCTCCTCAAACACTATCGGG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000434726.6; ENST00000542575.6; ENST00000412532.6; ENST00000594991.5
External Link	RMBase: m5C_site_25033
mod ID: M5CSITE002066		Click to Show/Hide the Full List
mod site	chr19:46775580-46775581:-		[4]
Sequence	TCCCCACTGAGGAAGGAAACCCCCTCCTCAAACACTATCGG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000412532.6; ENST00000542575.6; ENST00000434726.6; ENST00000594991.5
External Link	RMBase: m5C_site_25034
mod ID: M5CSITE002067		Click to Show/Hide the Full List
mod site	chr19:46778680-46778681:-		[4]
Sequence	GGCCACTGCCTTTGGGACCTCTTCCAGGTACGGCCTTGGGG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000412532.6; ENST00000434726.6; ENST00000593713.1; ENST00000594991.5; ENST00000542575.6
External Link	RMBase: m5C_site_25035
mod ID: M5CSITE002068		Click to Show/Hide the Full List
mod site	chr19:46780620-46780621:-		[4]
Sequence	TCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGGGGGA
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000412532.6; rmsk_5014520; ENST00000434726.6; ENST00000594991.5; ENST00000593713.1; ENST00000542575.6
External Link	RMBase: m5C_site_25036
mod ID: M5CSITE002069		Click to Show/Hide the Full List
mod site	chr19:46780625-46780626:-		[4]
Sequence	GTACCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000542575.6; rmsk_5014520; ENST00000434726.6; ENST00000593713.1; ENST00000594991.5; ENST00000412532.6
External Link	RMBase: m5C_site_25037
mod ID: M5CSITE002070		Click to Show/Hide the Full List
mod site	chr19:46780626-46780627:-		[4]
Sequence	GGTACCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAG
Seq Type List	Bisulfite-seq
Transcript ID List	ENST00000594991.5; ENST00000434726.6; rmsk_5014520; ENST00000412532.6; ENST00000593713.1; ENST00000542575.6
External Link	RMBase: m5C_site_25038

N6-methyladenosine (m6A)

In total 61 m6A sequence/site(s) in this target gene
mod ID: M6ASITE041632		Click to Show/Hide the Full List
mod site	chr19:46774921-46774922:-		[5]
Sequence	ACCTGCTGTCACTCCAGAGGACATTTTTTTTAGCAATAAAA
Motif Score	3.643047619
Cell/Tissue List	HEK293T; A549
Seq Type List	DART-seq; m6A-seq
Transcript ID List	ENST00000542575.6; ENST00000434726.6; ENST00000594991.5
External Link	RMBase: m6A_site_445566
mod ID: M6ASITE041633		Click to Show/Hide the Full List
mod site	chr19:46774947-46774948:-		[5]
Sequence	ACTCTGGGGAGAGGCTGAGGACAAATACCTGCTGTCACTCC
Motif Score	3.643047619
Cell/Tissue List	HEK293T; hESC-HEK293T; A549
Seq Type List	DART-seq; MAZTER-seq; m6A-seq; m6A-CLIP/IP
Transcript ID List	ENST00000434726.6; ENST00000542575.6; ENST00000412532.6; ENST00000594991.5
External Link	RMBase: m6A_site_445567
mod ID: M6ASITE041634		Click to Show/Hide the Full List
mod site	chr19:46774967-46774968:-		[6]
Sequence	TAACAGAAACACTCCCAGGGACTCTGGGGAGAGGCTGAGGA
Motif Score	4.065041667
Cell/Tissue List	A549
Seq Type List	m6A-seq
Transcript ID List	ENST00000542575.6; ENST00000594991.5; ENST00000412532.6; ENST00000434726.6
External Link	RMBase: m6A_site_445568
mod ID: M6ASITE041635		Click to Show/Hide the Full List
mod site	chr19:46774977-46774978:-		[5]
Sequence	CCCTCCACAATAACAGAAACACTCCCAGGGACTCTGGGGAG
Motif Score	2.506922619
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000412532.6; ENST00000542575.6; ENST00000594991.5; ENST00000434726.6
External Link	RMBase: m6A_site_445569
mod ID: M6ASITE041637		Click to Show/Hide the Full List
mod site	chr19:46774979-46774980:-		[5]
Sequence	TTCCCTCCACAATAACAGAAACACTCCCAGGGACTCTGGGG
Motif Score	2.20572619
Cell/Tissue List	HEK293T; A549
Seq Type List	DART-seq; m6A-seq
Transcript ID List	ENST00000594991.5; ENST00000542575.6; ENST00000434726.6; ENST00000412532.6
External Link	RMBase: m6A_site_445570
mod ID: M6ASITE041638		Click to Show/Hide the Full List
mod site	chr19:46774985-46774986:-		[7]
Sequence	CCCCTATTCCCTCCACAATAACAGAAACACTCCCAGGGACT
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T; AML
Seq Type List	MAZTER-seq; miCLIP
Transcript ID List	ENST00000434726.6; ENST00000542575.6; ENST00000412532.6; ENST00000594991.5
External Link	RMBase: m6A_site_445571
mod ID: M6ASITE041639		Click to Show/Hide the Full List
mod site	chr19:46774991-46774992:-		[7]
Sequence	CCAGATCCCCTATTCCCTCCACAATAACAGAAACACTCCCA
Motif Score	2.053113095
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000542575.6; ENST00000412532.6; ENST00000594991.5; ENST00000434726.6
External Link	RMBase: m6A_site_445572
mod ID: M6ASITE041640		Click to Show/Hide the Full List
mod site	chr19:46775027-46775028:-		[5]
Sequence	TGACCTCCTGTCCCCATGGTACGTCCCACCCTGTCCCCAGA
Motif Score	2.830077381
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000412532.6; ENST00000594991.5; ENST00000434726.6; ENST00000542575.6
External Link	RMBase: m6A_site_445573
mod ID: M6ASITE041641		Click to Show/Hide the Full List
mod site	chr19:46775091-46775092:-		[5]
Sequence	GTGGGGGGATGTGTGTGTGCACGTGTGTGTGTGTGTGTGTG
Motif Score	2.80452381
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000542575.6; ENST00000594991.5; ENST00000434726.6; ENST00000412532.6
External Link	RMBase: m6A_site_445574
mod ID: M6ASITE041642		Click to Show/Hide the Full List
mod site	chr19:46775143-46775144:-		[7]
Sequence	CCCACTGGGGGGATGTTACAACACCATGCTGGTTATTTTGG
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000594991.5; ENST00000434726.6; ENST00000542575.6; ENST00000412532.6
External Link	RMBase: m6A_site_445575
mod ID: M6ASITE041643		Click to Show/Hide the Full List
mod site	chr19:46775146-46775147:-		[5]
Sequence	GCCCCCACTGGGGGGATGTTACAACACCATGCTGGTTATTT
Motif Score	2.07285119
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000434726.6; ENST00000542575.6; ENST00000594991.5; ENST00000412532.6
External Link	RMBase: m6A_site_445576
mod ID: M6ASITE041644		Click to Show/Hide the Full List
mod site	chr19:46775267-46775268:-		[8]
Sequence	CCCCAACTCAAGGCTAGAAAACAGCAAGATGGAGAAATAAT
Motif Score	2.20572619
Cell/Tissue List	HepG2; A549; HEK293T; HeLa; MM6; peripheral-blood; iSLK; TREX; MSC; TIME; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000412532.6; ENST00000542575.6; ENST00000594991.5; ENST00000434726.6
External Link	RMBase: m6A_site_445577
mod ID: M6ASITE041645		Click to Show/Hide the Full List
mod site	chr19:46775295-46775296:-		[5]
Sequence	CCTCAAAACCCCCAGTTCTCACTCATGTCCCCAACTCAAGG
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000412532.6; ENST00000542575.6; ENST00000594991.5; ENST00000434726.6
External Link	RMBase: m6A_site_445578
mod ID: M6ASITE041646		Click to Show/Hide the Full List
mod site	chr19:46775308-46775309:-		[9]
Sequence	CACAAGGGTTACTCCTCAAAACCCCCAGTTCTCACTCATGT
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000434726.6; ENST00000412532.6; ENST00000542575.6; ENST00000594991.5
External Link	RMBase: m6A_site_445579
mod ID: M6ASITE041648		Click to Show/Hide the Full List
mod site	chr19:46775327-46775328:-		[5]
Sequence	CTGCTGGAGTACATGTGTTCACAAGGGTTACTCCTCAAAAC
Motif Score	2.047297619
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000542575.6; ENST00000412532.6; ENST00000434726.6; ENST00000594991.5
External Link	RMBase: m6A_site_445580
mod ID: M6ASITE041649		Click to Show/Hide the Full List
mod site	chr19:46775337-46775338:-		[5]
Sequence	GGATGCCTGGCTGCTGGAGTACATGTGTTCACAAGGGTTAC
Motif Score	2.856142857
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000434726.6; ENST00000412532.6; ENST00000594991.5; ENST00000542575.6
External Link	RMBase: m6A_site_445581
mod ID: M6ASITE041650		Click to Show/Hide the Full List
mod site	chr19:46775369-46775370:-		[9]
Sequence	GGGCCCCAGCACCCTCCAGGACAGGAGATCTGGGATGCCTG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; AML
Seq Type List	m6A-seq; MeRIP-seq; DART-seq; MAZTER-seq; miCLIP
Transcript ID List	ENST00000542575.6; ENST00000434726.6; ENST00000594991.5; ENST00000412532.6
External Link	RMBase: m6A_site_445582
mod ID: M6ASITE041651		Click to Show/Hide the Full List
mod site	chr19:46775406-46775407:-		[7]
Sequence	GGCTCTGGGGGTCTGCCTGCACACTCTGGGGAGCCAGGGGC
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000412532.6; ENST00000434726.6; ENST00000542575.6; ENST00000594991.5
External Link	RMBase: m6A_site_445583
mod ID: M6ASITE041652		Click to Show/Hide the Full List
mod site	chr19:46775464-46775465:-		[9]
Sequence	CTGCTGGGGGTGCTCTTTGGACACTGGATTATGAGGAATGG
Motif Score	3.643047619
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; CD8T; H1299; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000542575.6; ENST00000434726.6; ENST00000412532.6; ENST00000594991.5
External Link	RMBase: m6A_site_445584
mod ID: M6ASITE041653		Click to Show/Hide the Full List
mod site	chr19:46775496-46775497:-		[9]
Sequence	TCATGTAAACCCCGGGAGGGACCTTCCCTGCCCTGCTGGGG
Motif Score	3.622404762
Cell/Tissue List	HeLa; CD34; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6; ENST00000434726.6; ENST00000594991.5; ENST00000412532.6
External Link	RMBase: m6A_site_445585
mod ID: M6ASITE041654		Click to Show/Hide the Full List
mod site	chr19:46775508-46775509:-		[9]
Sequence	AGAAGGAATCAGTCATGTAAACCCCGGGAGGGACCTTCCCT
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; peripheral-blood; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6; ENST00000434726.6; ENST00000412532.6; ENST00000594991.5
External Link	RMBase: m6A_site_445586
mod ID: M6ASITE041655		Click to Show/Hide the Full List
mod site	chr19:46775569-46775570:-		[9]
Sequence	GAAGGAAACCCCCTCCTCAAACACTATCGGGGGCCCGCAGG
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T; hESC-HEK293T; HepG2; U2OS; hESCs; fibroblasts; A549; MM6; Huh7; HEK293A-TOA; TREX
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000434726.6; ENST00000542575.6; ENST00000412532.6; ENST00000594991.5
External Link	RMBase: m6A_site_445587
mod ID: M6ASITE041656		Click to Show/Hide the Full List
mod site	chr19:46775582-46775583:-		[9]
Sequence	AGTCCCCACTGAGGAAGGAAACCCCCTCCTCAAACACTATC
Motif Score	2.185083333
Cell/Tissue List	HeLa; HEK293T; HepG2; U2OS; hESCs; fibroblasts; A549; MM6; Huh7; HEK293A-TOA; TREX
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6; ENST00000434726.6; ENST00000594991.5; ENST00000412532.6
External Link	RMBase: m6A_site_445588
mod ID: M6ASITE041657		Click to Show/Hide the Full List
mod site	chr19:46775638-46775639:-		[7]
Sequence	AGCACAGAGCCTGAGTTGATACAAGTGAAGAGTGAGCTGCC
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000594991.5; ENST00000412532.6; ENST00000434726.6; ENST00000542575.6
External Link	RMBase: m6A_site_445589
mod ID: M6ASITE041659		Click to Show/Hide the Full List
mod site	chr19:46775675-46775676:-		[10]
Sequence	ACTCCTCCAAAATTACGTGGACCGTACGGAGTCGAGAAGCA
Motif Score	3.622404762
Cell/Tissue List	HepG2; MM6; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000412532.6; ENST00000542575.6; ENST00000434726.6; ENST00000594991.5
External Link	RMBase: m6A_site_445590
mod ID: M6ASITE041660		Click to Show/Hide the Full List
mod site	chr19:46775695-46775696:-		[10]
Sequence	GGTGACGCTCTGGGGGCAGGACTCCTCCAAAATTACGTGGA
Motif Score	4.065041667
Cell/Tissue List	HepG2; Huh7; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000412532.6; ENST00000594991.5; ENST00000542575.6; ENST00000434726.6
External Link	RMBase: m6A_site_445591
mod ID: M6ASITE041661		Click to Show/Hide the Full List
mod site	chr19:46776983-46776984:-		[10]
Sequence	CTCCTTGATCCTGGCTGTGGACTGGCTAGTGTGAGTGTGGG
Motif Score	4.065041667
Cell/Tissue List	HepG2; Huh7; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000594991.5; ENST00000434726.6; ENST00000412532.6; ENST00000542575.6
External Link	RMBase: m6A_site_445594
mod ID: M6ASITE041662		Click to Show/Hide the Full List
mod site	chr19:46777234-46777235:-		[10]
Sequence	GCTCAGCCAGCAGTCCTTGGACTTCGTAAAGATCATCACCA
Motif Score	4.065041667
Cell/Tissue List	HepG2; Huh7; peripheral-blood
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000412532.6; ENST00000542575.6; ENST00000593713.1; ENST00000434726.6; ENST00000594991.5
External Link	RMBase: m6A_site_445595
mod ID: M6ASITE041663		Click to Show/Hide the Full List
mod site	chr19:46777306-46777307:-		[7]
Sequence	GCCCATCGGCGCCACCGTCAACATGGACGGTGCCGCGCTCT
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000594991.5; ENST00000434726.6; ENST00000542575.6; ENST00000412532.6; ENST00000593713.1
External Link	RMBase: m6A_site_445596
mod ID: M6ASITE041664		Click to Show/Hide the Full List
mod site	chr19:46777345-46777346:-		[7]
Sequence	GAATAATGGCGTGGCCAAGCACATCAGCCGTTTCATCCTGC
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000593713.1; ENST00000594991.5; ENST00000434726.6; ENST00000412532.6; ENST00000542575.6
External Link	RMBase: m6A_site_445597
mod ID: M6ASITE041665		Click to Show/Hide the Full List
mod site	chr19:46778684-46778685:-		[11]
Sequence	CGCTGGCCACTGCCTTTGGGACCTCTTCCAGGTACGGCCTT
Motif Score	3.622404762
Cell/Tissue List	HepG2; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6; ENST00000594991.5; ENST00000593713.1; ENST00000412532.6; ENST00000434726.6
External Link	RMBase: m6A_site_445598
mod ID: M6ASITE041666		Click to Show/Hide the Full List
mod site	chr19:46778737-46778738:-		[12]
Sequence	CTTCCTCTTCACCCGCAAAAACCCCTACCGCTTCCTGTGGG
Motif Score	2.185083333
Cell/Tissue List	Huh7
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000593713.1; ENST00000594991.5; ENST00000434726.6; ENST00000542575.6; ENST00000412532.6
External Link	RMBase: m6A_site_445599
mod ID: M6ASITE041668		Click to Show/Hide the Full List
mod site	chr19:46778818-46778819:-		[7]
Sequence	CTTTGCCCGCCTTGGCAAGTACATTCTGTGCTGCCTGCTGG
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000434726.6; ENST00000594991.5; ENST00000593713.1; ENST00000542575.6; ENST00000412532.6
External Link	RMBase: m6A_site_445600
mod ID: M6ASITE041669		Click to Show/Hide the Full List
mod site	chr19:46782517-46782518:-		[9]
Sequence	GCAGGAGGTGGAGGGGATGAACATCCTGGGCTTGGTAGTGT
Motif Score	2.951386905
Cell/Tissue List	HeLa; HepG2; hESC-HEK293T
Seq Type List	m6A-seq; MAZTER-seq
Transcript ID List	ENST00000598022.1; ENST00000594991.5; ENST00000542575.6; ENST00000593713.1; ENST00000412532.6; ENST00000434726.6
External Link	RMBase: m6A_site_445601
mod ID: M6ASITE041670		Click to Show/Hide the Full List
mod site	chr19:46784107-46784108:-		[13]
Sequence	AAGAGAGGAATATCACCGGAACCAGGGTGAAGGTGAGAGCA
Motif Score	2.930744048
Cell/Tissue List	HepG2
Seq Type List	m6A-seq
Transcript ID List	ENST00000542575.6; ENST00000598022.1; ENST00000593713.1; ENST00000412532.6; ENST00000594991.5; ENST00000434726.6
External Link	RMBase: m6A_site_445602
mod ID: M6ASITE041671		Click to Show/Hide the Full List
mod site	chr19:46784615-46784616:-		[5]
Sequence	ACGCCAACCCAGCCTCTCAGACAATGCTGCCCTCCCACTAT
Motif Score	2.897386905
Cell/Tissue List	HEK293T; peripheral-blood; MM6
Seq Type List	DART-seq; m6A-seq
Transcript ID List	ENST00000434726.6; ENST00000412532.6; ENST00000598022.1; ENST00000593713.1; ENST00000542575.6; ENST00000594991.5
External Link	RMBase: m6A_site_445603
mod ID: M6ASITE041672		Click to Show/Hide the Full List
mod site	chr19:46784806-46784807:-		[9]
Sequence	GCCAGCATTCCTCACCCCGAACCCACAATGCCTCAGGGCTA
Motif Score	2.930744048
Cell/Tissue List	HeLa; peripheral-blood
Seq Type List	m6A-seq
Transcript ID List	ENST00000412532.6; ENST00000542575.6; ENST00000594991.5; ENST00000434726.6
External Link	RMBase: m6A_site_445604
mod ID: M6ASITE041673		Click to Show/Hide the Full List
mod site	chr19:46787302-46787303:-		[10]
Sequence	TTGGGGCCCCTGGAGCAGAGACTTCCCTCTAGAGTCTTAGG
Motif Score	3.319380952
Cell/Tissue List	HepG2; HEK293T; NB4; MM6
Seq Type List	m6A-seq
Transcript ID List	ENST00000412532.6; ENST00000542575.6
External Link	RMBase: m6A_site_445605
mod ID: M6ASITE041674		Click to Show/Hide the Full List
mod site	chr19:46787335-46787336:-		[10]
Sequence	TGGCGGGAGTGGTCACGTGGACAGGACGGGGCTTTGGGGCC
Motif Score	3.643047619
Cell/Tissue List	HepG2; HEK293T; TREX; NB4; MM6
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6; ENST00000412532.6
External Link	RMBase: m6A_site_445606
mod ID: M6ASITE041675		Click to Show/Hide the Full List
mod site	chr19:46787606-46787607:-		[9]
Sequence	CGGCGGCGCCGCCAGCCTGGACCCCGGCGCGCTCGGCCGTC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; A549; HEK293T; U2OS; H1A; H1B; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TREX; TIME; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445607
mod ID: M6ASITE041676		Click to Show/Hide the Full List
mod site	chr19:46787758-46787759:-		[9]
Sequence	GTGGCCGGCGTGGCGCTGGGACTGGGGGTGTCGGGGGCCGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445608
mod ID: M6ASITE041677		Click to Show/Hide the Full List
mod site	chr19:46787793-46787794:-		[7]
Sequence	CCAACCTGCTTGTGCTGCTGACAGTGGTGGCCGTGGTGGCC
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T; AML
Seq Type List	MAZTER-seq; miCLIP
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445609
mod ID: M6ASITE041679		Click to Show/Hide the Full List
mod site	chr19:46787837-46787838:-		[9]
Sequence	CGGCTACTGCGGTTCCCGGGACCAGGTGCGCCGCTGCCTTC
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445610
mod ID: M6ASITE041680		Click to Show/Hide the Full List
mod site	chr19:46787876-46787877:-		[9]
Sequence	GGCGCTGGCCTCCATCGAGGACCAAGGCGCGGCAGCAGGCG
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445612
mod ID: M6ASITE041681		Click to Show/Hide the Full List
mod site	chr19:46787942-46787943:-		[9]
Sequence	GGTGGCCGATCCTCCTCGAGACTCCAAGGGGCTCGCAGCGG
Motif Score	3.319380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; CD8T; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445613
mod ID: M6ASITE041682		Click to Show/Hide the Full List
mod site	chr19:46787982-46787983:-		[9]
Sequence	CAGCTTCCAGGCGCTAAGAAACCCCGGTGCTTCCCATCATG
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445614
mod ID: M6ASITE041683		Click to Show/Hide the Full List
mod site	chr19:46788103-46788104:-		[7]
Sequence	AACTTCAGTGCTGTGAACTCACAACTCTAAGGAGCCCTCCA
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445619
mod ID: M6ASITE041685		Click to Show/Hide the Full List
mod site	chr19:46788107-46788108:-		[9]
Sequence	AAGGAACTTCAGTGCTGTGAACTCACAACTCTAAGGAGCCC
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP; miCLIP
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445620
mod ID: M6ASITE041686		Click to Show/Hide the Full List
mod site	chr19:46788122-46788123:-		[9]
Sequence	CAGCTTCCAAGAGCCAAGGAACTTCAGTGCTGTGAACTCAC
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445621
mod ID: M6ASITE041687		Click to Show/Hide the Full List
mod site	chr19:46788148-46788149:-		[9]
Sequence	GCCCAGCCTGGGGAATTTAAACACTCCAGCTTCCAAGAGCC
Motif Score	2.20572619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; MAZTER-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445622
mod ID: M6ASITE041688		Click to Show/Hide the Full List
mod site	chr19:46788196-46788197:-		[7]
Sequence	CCAGCTTTCGGACATCTGGCACACGGGGCAGAGCAGAGAAG
Motif Score	2.830589286
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445623
mod ID: M6ASITE041689		Click to Show/Hide the Full List
mod site	chr19:46788205-46788206:-		[9]
Sequence	TCCGAACTCCCAGCTTTCGGACATCTGGCACACGGGGCAGA
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; kidney; A549; hESC-HEK293T; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq; m6A-REF-seq; MAZTER-seq; m6A-CLIP/IP
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445624
mod ID: M6ASITE041690		Click to Show/Hide the Full List
mod site	chr19:46788220-46788221:-		[9]
Sequence	AAGGAACCCGGGCGCTCCGAACTCCCAGCTTTCGGACATCT
Motif Score	3.373380952
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP; miCLIP
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445625
mod ID: M6ASITE041691		Click to Show/Hide the Full List
mod site	chr19:46788235-46788236:-		[9]
Sequence	CCAGCTCCTAGGGCCAAGGAACCCGGGCGCTCCGAACTCCC
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; miCLIP
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445626
mod ID: M6ASITE041692		Click to Show/Hide the Full List
mod site	chr19:46788267-46788268:-		[9]
Sequence	CCCACGTCCCACCCAGAGAAACTCTCGTATTCCCAGCTCCT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hNPCs; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4; AML
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP; miCLIP
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445627
mod ID: M6ASITE041693		Click to Show/Hide the Full List
mod site	chr19:46788330-46788331:-		[9]
Sequence	CAGAACCTAGCCTCCTGCAGACCTCCGCCATCTGGGGGCAC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445628
mod ID: M6ASITE041694		Click to Show/Hide the Full List
mod site	chr19:46788346-46788347:-		[9]
Sequence	CCGGGATCTGCGCCACCAGAACCTAGCCTCCTGCAGACCTC
Motif Score	2.930744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; H1299; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445629
mod ID: M6ASITE041696		Click to Show/Hide the Full List
mod site	chr19:46788406-46788407:-		[9]
Sequence	CCCAGCCCTCAGTGTCCAAGACCCAGGCAGCCCGGGTCCCC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; GM12878; LCLs; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445631
mod ID: M6ASITE041697		Click to Show/Hide the Full List
mod site	chr19:46788487-46788488:-		[9]
Sequence	CCCGCATCCCACCCTCCCGGACCTAAGAGCCTGGGTCCCCT
Motif Score	3.622404762
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MT4; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445636
mod ID: M6ASITE041698		Click to Show/Hide the Full List
mod site	chr19:46788531-46788532:-		[9]
Sequence	CCGCTACTCCCGGACACCAGACCACCGCCTTCCGTACACAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MT4; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; GSCs; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445637
mod ID: M6ASITE041699		Click to Show/Hide the Full List
mod site	chr19:46788538-46788539:-		[9]
Sequence	CTGGTAACCGCTACTCCCGGACACCAGACCACCGCCTTCCG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HepG2; HEK293T; A549; U2OS; H1A; H1B; hESCs; fibroblasts; GM12878; LCLs; MT4; MM6; Huh7; Jurkat; CD4T; peripheral-blood; GSC-11; HEK293A-TOA; iSLK; MSC; TIME; TREX; endometrial; HEC-1-A; NB4
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000542575.6
External Link	RMBase: m6A_site_445638

Ref 1	The m(6)A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor. Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21441-21449. doi: 10.1073/pnas.2000516117. Epub 2020 Aug 19.
Ref 2	Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Nat Biotechnol. 2012 Feb 12;30(3):253-60. doi: 10.1038/nbt.2122.
Ref 3	Identification of widespread ultra-edited human RNAs. PLoS Genet. 2011 Oct;7(10):e1002317. doi: 10.1371/journal.pgen.1002317. Epub 2011 Oct 20.
Ref 4	5-methylcytosine promotes mRNA export - NSUN2 as the methyltransferase and ALYREF as an m(5)C reader. Cell Res. 2017 May;27(5):606-625. doi: 10.1038/cr.2017.55. Epub 2017 Apr 18.
Ref 5	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 6	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10;8(1):284-96. doi: 10.1016/j.celrep.2014.05.048. Epub 2014 Jun 26.
Ref 7	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 8	Histone H3 trimethylation at lysine 36 guides m(6)A RNA modification co-transcriptionally. Nature. 2019 Mar;567(7748):414-419. doi: 10.1038/s41586-019-1016-7. Epub 2019 Mar 13.
Ref 9	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 10	Efficacy of MEK inhibition in patients with histiocytic neoplasms. Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.
Ref 11	Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq. Nature. 2012 Apr 29;485(7397):201-6. doi: 10.1038/nature11112.
Ref 12	N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection. Cell Host Microbe. 2016 Nov 9;20(5):654-665. doi: 10.1016/j.chom.2016.09.015. Epub 2016 Oct 20.
Ref 13	[Action myoclonias and paranoid alternative psychosis in progressive myoclonic epilepsy (late form of the Lafora type)]. Nervenarzt. 1986 Apr;57(4):233-7.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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