m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00117)
Target Name Small nucleolar RNA host gene 1 (SNHG1)
Synonyms
SNHG1; small nucleolar RNA host gene 1 (non-protein coding); UHG; NCRNA00057; LINC00057; lncRNA16; U22 snoRNA host gene; non-protein coding RNA 57; long intergenic non-protein coding RNA 57
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Gene Name SNHG1
Chromosomal Location 11q12.3
Family Small nucleolar RNA non-coding host genes
Gene ID 23642
HGNC ID
HGNC:32688
Ensembl Gene ID
ENSG00000255717
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
SNHG1 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Regulator
Browse Disease
Methyltransferase-like 3 (METTL3) [WRITER]
 Regulator Info 
Representative RNA-seq result indicating the expression of this target gene regulated by METTL3
Cell Line ARPE-19 cell line Homo sapiens
Treatment: shMETTL3 ARPE-19 cells
Control: shControl ARPE-19 cells
 GSE202017
Regulation
logFC: -1.12E+00
p-value: 7.04E-06
More Results Click to View More RNA-seq Results
Representative RIP-seq result supporting the interaction between SNHG1 and the regulator
Cell Line MDA-MB-231 Homo sapiens
Regulation logFC: 1.90E+00 GSE60213
In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene [1]
Response Summary METTL3/Small nucleolar RNA host gene 1 (SNHG1)/miR-140-3p/UBE2C axis plays a crucial role in cancer progression and the immune response in non-small cell lung cancer.
Target Regulation Up regulation
Responsed Disease Non-small-cell lung carcinoma ICD-11: 2C25.Y
 Disease Info 
In-vitro Model A-549 Lung adenocarcinoma Homo sapiens CVCL_0023
BEAS-2B Normal Homo sapiens CVCL_0168
NCI-H1299 Lung large cell carcinoma Homo sapiens CVCL_0060
NCI-H1975 Lung adenocarcinoma Homo sapiens CVCL_1511
Lung cancer [ICD-11: 2C25]
 Disease Info 
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response [1]
Response Summary METTL3/Small nucleolar RNA host gene 1 (SNHG1)/miR-140-3p/UBE2C axis plays a crucial role in cancer progression and the immune response in non-small cell lung cancer.
Responsed Disease Non-small-cell lung carcinoma [ICD-11: 2C25.Y]
Target Regulator Methyltransferase-like 3 (METTL3) WRITER
 Regulator Info 
Target Regulation Up regulation
In-vitro Model A-549 Lung adenocarcinoma Homo sapiens CVCL_0023
BEAS-2B Normal Homo sapiens CVCL_0168
NCI-H1299 Lung large cell carcinoma Homo sapiens CVCL_0060
NCI-H1975 Lung adenocarcinoma Homo sapiens CVCL_1511
References
Ref 1 Comprehensive Pan-Cancer Analysis of the Prognostic and Immunological Roles of the METTL3/lncRNA-SNHG1/miRNA-140-3p/UBE2C Axis. Front Cell Dev Biol. 2021 Nov 10;9:765772. doi: 10.3389/fcell.2021.765772. eCollection 2021.