m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00117)

Target Name	Small nucleolar RNA host gene 1 (SNHG1)
Synonyms	SNHG1; small nucleolar RNA host gene 1 (non-protein coding); UHG; NCRNA00057; LINC00057; lncRNA16; U22 snoRNA host gene; non-protein coding RNA 57; long intergenic non-protein coding RNA 57 Click to Show/Hide
Gene Name	SNHG1
Chromosomal Location	11q12.3
Family	Small nucleolar RNA non-coding host genes
Gene ID	23642
HGNC ID	HGNC:32688

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

SNHG1 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Regulator

Browse Disease

Methyltransferase-like 3 (METTL3) [WRITER]

Regulator Info

*Representative RNA-seq result indicating the expression of this target gene regulated by METTL3*
Cell Line	ARPE-19 cell line	Homo sapiens
Treatment: shMETTL3 ARPE-19 cells Control: shControl ARPE-19 cells		GSE202017
Regulation		logFC: -1.12E+00 p-value: 7.04E-06
More Results	Click to View More RNA-seq Results
*Representative RIP-seq result supporting the interaction between SNHG1 and the regulator*
Cell Line	MDA-MB-231	Homo sapiens
Regulation	logFC: 1.90E+00	GSE60213

In total 1 item(s) under this regulator
Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene				[1]
Response Summary	METTL3/Small nucleolar RNA host gene 1 (SNHG1)/miR-140-3p/UBE2C axis plays a crucial role in cancer progression and the immune response in non-small cell lung cancer.
Target Regulation	Up regulation
Responsed Disease	Non-small-cell lung carcinoma		ICD-11: 2C25.Y	Disease Info
In-vitro Model	A-549	Lung adenocarcinoma	Homo sapiens	CVCL_0023
	BEAS-2B	Normal	Homo sapiens	CVCL_0168
	NCI-H1299	Lung large cell carcinoma	Homo sapiens	CVCL_0060
	NCI-H1975	Lung adenocarcinoma	Homo sapiens	CVCL_1511

Lung cancer [ICD-11: 2C25]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response				[1]
Response Summary	METTL3/Small nucleolar RNA host gene 1 (SNHG1)/miR-140-3p/UBE2C axis plays a crucial role in cancer progression and the immune response in non-small cell lung cancer.
Responsed Disease	Non-small-cell lung carcinoma [ICD-11: 2C25.Y]
Target Regulator	Methyltransferase-like 3 (METTL3)		WRITER	Regulator Info
Target Regulation	Up regulation
In-vitro Model	A-549	Lung adenocarcinoma	Homo sapiens	CVCL_0023
	BEAS-2B	Normal	Homo sapiens	CVCL_0168
	NCI-H1299	Lung large cell carcinoma	Homo sapiens	CVCL_0060
	NCI-H1975	Lung adenocarcinoma	Homo sapiens	CVCL_1511

Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator

Histone modification

m6A Regulator: Methyltransferase-like 3 (METTL3)

Regulator Info

In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT03582		Crosstalk Info
Epigenetic Regulator	Histone acetyltransferase p300 (P300)
Regulated Target	Histone H3 lysine 27 acetylation (H3K27ac)
Crosstalk relationship	Histone modification → m6A
Disease	Colorectal cancer	Disease Info
Crosstalk ID: M6ACROT03627		Crosstalk Info
Epigenetic Regulator	N-lysine methyltransferase SMYD2 (SMYD2)
Regulated Target	Histone H3 lysine 4 trimethylation (H3K4me3)
Crosstalk relationship	Histone modification → m6A
Disease	Colorectal cancer	Disease Info

Non-coding RNA

m6A Regulator: Methyltransferase-like 3 (METTL3)

Regulator Info

In total 2 item(s) under this m6A regulator
Crosstalk ID: M6ACROT05545		Crosstalk Info
Epigenetic Regulator	Small nucleolar RNA host gene 1 (SNHG1)
Regulated Target	hsa-miR-140-3p
Crosstalk relationship	m6A → ncRNA
Disease	Non-small cell lung cancer	Disease Info
Crosstalk ID: M6ACROT05701		Crosstalk Info
Epigenetic Regulator	Small nucleolar RNA host gene 1 (SNHG1)
Crosstalk relationship	m6A → ncRNA
Disease	Colorectal cancer	Disease Info

RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00117)

Small nucleolar RNA host gene 1 (SNHG1)

2'-O-Methylation (2'-O-Me)

In total 1 m6A sequence/site(s) in this target gene
mod ID: 2OMSITE000608		Click to Show/Hide the Full List
mod site	chr11:62853674-62853675:-		[3]
Sequence	GACTTGCTGTTGAGACTCTGAAATCTGATTTTCTGAGAATG
Cell/Tissue List	HeLa
Seq Type List	Nm-seq
Transcript ID List	ENST00000545688.5; ENST00000541578.5; ENST00000545440.5; ENST00000535076.5; ENST00000538654.5; ENST00000539975.5; ENST00000537068.5; ENST00000538266.5; ENST00000544550.5; ENST00000540865.5; ENST00000541615.5; ENST00000539303.5; ENST00000384693.1; ENST00000537925.5; ENST00000537024.5; ENST00000540725.5; ENST00000542112.5; ENST00000537869.5; ENST00000539921.5; ENST00000535689.5; ENST00000545920.1
External Link	RMBase: Nm_site_978

N6-methyladenosine (m6A)

In total 54 m6A sequence/site(s) in this target gene
mod ID: M6ASITE006289		Click to Show/Hide the Full List
mod site	chr11:62851991-62851992:-		[4]
Sequence	AAATAATAAAATGATTGATTACATAGTCCTGTTTACTTTTT
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000539921.5; ENST00000537068.5; ENST00000538654.5; ENST00000540725.5; ENST00000537925.5; ENST00000537869.5
External Link	RMBase: m6A_site_145024
mod ID: M6ASITE006290		Click to Show/Hide the Full List
mod site	chr11:62852051-62852052:-		[5]
Sequence	CAAAAAAGGTTCCCTTGAGGACTGGCTGTCAATTTGTGTTG
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000539921.5; ENST00000539975.5; ENST00000537068.5; ENST00000537925.5; ENST00000535076.5; ENST00000540725.5; ENST00000538654.5; ENST00000537869.5
External Link	RMBase: m6A_site_145025
mod ID: M6ASITE006291		Click to Show/Hide the Full List
mod site	chr11:62852075-62852076:-		[6]
Sequence	CATTCAGGGCCTTGCTCTTCACTTCAAAAAAGGTTCCCTTG
Motif Score	2.469291667
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000537925.5; ENST00000539975.5; ENST00000539921.5; ENST00000537068.5; ENST00000535076.5; ENST00000540725.5; ENST00000537869.5; ENST00000538654.5
External Link	RMBase: m6A_site_145026
mod ID: M6ASITE006292		Click to Show/Hide the Full List
mod site	chr11:62852174-62852175:-		[7]
Sequence	TCGTGTCTGTTCCTCTGTATACAGCCACCTTCTGTTCCCGT
Motif Score	2.110482143
Cell/Tissue List	brain
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000540725.5; ENST00000538654.5; ENST00000535076.5; ENST00000537068.5; ENST00000537925.5; ENST00000539975.5; ENST00000539921.5; ENST00000537869.5
External Link	RMBase: m6A_site_145027
mod ID: M6ASITE006293		Click to Show/Hide the Full List
mod site	chr11:62852212-62852213:-		[5]
Sequence	TGTTGCCAATTGTTGATTGAACTTCCCATAACTCCACTTCG
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000539921.5; ENST00000537869.5; ENST00000537925.5; ENST00000537068.5; ENST00000535076.5; ENST00000540725.5; ENST00000539975.5; ENST00000538654.5
External Link	RMBase: m6A_site_145028
mod ID: M6ASITE006294		Click to Show/Hide the Full List
mod site	chr11:62852240-62852241:-		[6]
Sequence	ACCACTTTCGTAAACTACTGACCTAGCTTGTTGCCAATTGT
Motif Score	2.839113095
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000539921.5; ENST00000540725.5; ENST00000537869.5; ENST00000539975.5; ENST00000535076.5; ENST00000537925.5; ENST00000537068.5; ENST00000538654.5
External Link	RMBase: m6A_site_145029
mod ID: M6ASITE006295		Click to Show/Hide the Full List
mod site	chr11:62852244-62852245:-		[6]
Sequence	GATGACCACTTTCGTAAACTACTGACCTAGCTTGTTGCCAA
Motif Score	2.500660714
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000539975.5; ENST00000538654.5; ENST00000535076.5; ENST00000539921.5; ENST00000540725.5; ENST00000537068.5; ENST00000537925.5; ENST00000537869.5
External Link	RMBase: m6A_site_145030
mod ID: M6ASITE006296		Click to Show/Hide the Full List
mod site	chr11:62852247-62852248:-		[5]
Sequence	ATAGATGACCACTTTCGTAAACTACTGACCTAGCTTGTTGC
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000538654.5; ENST00000537068.5; ENST00000540725.5; ENST00000537925.5; ENST00000535076.5; ENST00000537869.5; ENST00000539975.5; ENST00000539921.5
External Link	RMBase: m6A_site_145031
mod ID: M6ASITE006297		Click to Show/Hide the Full List
mod site	chr11:62852280-62852281:-		[5]
Sequence	GATCCAGGCCCAGAACCCAAACTCAGGCACTGTATAGATGA
Motif Score	2.627720238
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000538654.5; ENST00000537068.5; ENST00000539975.5; ENST00000535076.5; ENST00000542112.5; ENST00000545440.5; ENST00000540725.5; ENST00000539921.5; ENST00000537925.5; ENST00000537869.5
External Link	RMBase: m6A_site_145032
mod ID: M6ASITE006298		Click to Show/Hide the Full List
mod site	chr11:62852286-62852287:-		[5]
Sequence	TTACATGATCCAGGCCCAGAACCCAAACTCAGGCACTGTAT
Motif Score	2.930744048
Cell/Tissue List	HeLa; HEK293T
Seq Type List	m6A-seq; DART-seq
Transcript ID List	ENST00000537869.5; ENST00000540725.5; ENST00000537925.5; ENST00000537068.5; ENST00000539921.5; ENST00000545440.5; ENST00000535076.5; ENST00000539975.5; ENST00000538654.5; ENST00000542112.5
External Link	RMBase: m6A_site_145033
mod ID: M6ASITE006299		Click to Show/Hide the Full List
mod site	chr11:62852304-62852305:-		[6]
Sequence	CAGACTTTGCTGCCTTTCTTACATGATCCAGGCCCAGAACC
Motif Score	2.07285119
Cell/Tissue List	HEK293T; hESC-HEK293T
Seq Type List	DART-seq; MAZTER-seq
Transcript ID List	ENST00000540725.5; ENST00000539921.5; ENST00000538654.5; ENST00000545440.5; ENST00000537869.5; ENST00000537925.5; ENST00000539975.5; ENST00000541615.5; ENST00000535076.5; ENST00000541578.5; ENST00000537068.5; ENST00000542112.5
External Link	RMBase: m6A_site_145034
mod ID: M6ASITE006300		Click to Show/Hide the Full List
mod site	chr11:62852321-62852322:-		[5]
Sequence	GTGTGATTCATGGCACCCAGACTTTGCTGCCTTTCTTACAT
Motif Score	3.319380952
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000541578.5; ENST00000545440.5; ENST00000542112.5; ENST00000535076.5; ENST00000537068.5; ENST00000540725.5; ENST00000539921.5; ENST00000538654.5; ENST00000537869.5; ENST00000539975.5; ENST00000537925.5; ENST00000541615.5
External Link	RMBase: m6A_site_145035
mod ID: M6ASITE006301		Click to Show/Hide the Full List
mod site	chr11:62852369-62852370:-		[7]
Sequence	CTTTAAGAGATCCTCTCACCACAGATTTCCAAAGTGCTGGG
Motif Score	2.053113095
Cell/Tissue List	HEK293
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000537068.5; ENST00000535076.5; ENST00000539921.5; ENST00000537869.5; ENST00000545440.5; ENST00000540725.5; ENST00000539975.5; ENST00000537925.5; ENST00000541615.5; ENST00000541578.5; ENST00000542112.5; ENST00000538654.5
External Link	RMBase: m6A_site_145036
mod ID: M6ASITE006302		Click to Show/Hide the Full List
mod site	chr11:62852433-62852434:-		[4]
Sequence	TGCCCTTTTGTTTTTTAGATACAAGGGCTTGGTTTTGTTAC
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000537925.5; ENST00000540725.5; ENST00000545440.5; ENST00000539921.5; ENST00000541615.5; ENST00000539975.5; ENST00000538654.5; ENST00000535076.5; ENST00000537869.5; ENST00000542112.5; ENST00000537068.5; ENST00000541578.5
External Link	RMBase: m6A_site_145037
mod ID: M6ASITE006303		Click to Show/Hide the Full List
mod site	chr11:62852476-62852477:-		[4]
Sequence	TTTATCACCCCCTTCCTGCAACATTATTTATCTGGAATCTA
Motif Score	2.173910714
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000537068.5; ENST00000537925.5; ENST00000539975.5; ENST00000542112.5; ENST00000541578.5; ENST00000537869.5; ENST00000541615.5; ENST00000540725.5; ENST00000545440.5; ENST00000539921.5; ENST00000538654.5; ENST00000535076.5
External Link	RMBase: m6A_site_145038
mod ID: M6ASITE006304		Click to Show/Hide the Full List
mod site	chr11:62852535-62852536:-		[5]
Sequence	AGACACTGGGAGCCAATGAAACAGCAGTTGAGGGTTTGCTG
Motif Score	2.20572619
Cell/Tissue List	HeLa
Seq Type List	m6A-seq
Transcript ID List	ENST00000535076.5; ENST00000545440.5; ENST00000537869.5; ENST00000537925.5; ENST00000541615.5; ENST00000539921.5; ENST00000539975.5; ENST00000542112.5; ENST00000541578.5; ENST00000537068.5; ENST00000540725.5; ENST00000538654.5
External Link	RMBase: m6A_site_145039
mod ID: M6ASITE006305		Click to Show/Hide the Full List
mod site	chr11:62852553-62852554:-		[6]
Sequence	GTTAGCAGACACAGATTAAGACACTGGGAGCCAATGAAACA
Motif Score	2.897386905
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000535076.5; ENST00000537925.5; ENST00000537068.5; ENST00000539975.5; ENST00000540725.5; ENST00000541578.5; ENST00000542112.5; ENST00000545440.5; ENST00000538654.5; ENST00000537869.5; ENST00000541615.5; ENST00000539921.5
External Link	RMBase: m6A_site_145040
mod ID: M6ASITE006306		Click to Show/Hide the Full List
mod site	chr11:62852565-62852566:-		[4]
Sequence	GTACCTTAAAGTGTTAGCAGACACAGATTAAGACACTGGGA
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000541615.5; ENST00000538654.5; ENST00000537869.5; ENST00000537925.5; ENST00000540725.5; ENST00000541578.5; ENST00000545440.5; ENST00000539975.5; ENST00000542112.5; ENST00000535076.5; ENST00000539921.5; ENST00000537068.5
External Link	RMBase: m6A_site_145041
mod ID: M6ASITE006307		Click to Show/Hide the Full List
mod site	chr11:62852583-62852584:-		[6]
Sequence	TTGGGGGGTATTTCAGATGTACCTTAAAGTGTTAGCAGACA
Motif Score	2.8355
Cell/Tissue List	HEK293T
Seq Type List	DART-seq
Transcript ID List	ENST00000535076.5; ENST00000541578.5; ENST00000538654.5; ENST00000537925.5; ENST00000539921.5; ENST00000540725.5; ENST00000537869.5; ENST00000545440.5; ENST00000541615.5; ENST00000537068.5; ENST00000539975.5; ENST00000542112.5
External Link	RMBase: m6A_site_145042
mod ID: M6ASITE006308		Click to Show/Hide the Full List
mod site	chr11:62852633-62852634:-		[4]
Sequence	TGAATTTTCCAAGTTCTTGGACAACCTAGCTGTTGAAAAGC
Motif Score	3.643047619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000542112.5; ENST00000539921.5; ENST00000535076.5; ENST00000541615.5; ENST00000545440.5; ENST00000537925.5; ENST00000541578.5; ENST00000540725.5; ENST00000538654.5; ENST00000537869.5; ENST00000537068.5; ENST00000538266.5; ENST00000539975.5
External Link	RMBase: m6A_site_145043
mod ID: M6ASITE006309		Click to Show/Hide the Full List
mod site	chr11:62852664-62852665:-		[4]
Sequence	GCAGGAATCTGTCTTGGAGGACATCAGAAGGTGAATTTTCC
Motif Score	3.643047619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000539921.5; ENST00000539975.5; ENST00000538654.5; ENST00000541615.5; ENST00000537925.5; ENST00000535076.5; ENST00000541578.5; ENST00000537869.5; ENST00000537068.5; ENST00000538266.5; ENST00000542112.5; ENST00000545440.5; ENST00000540725.5
External Link	RMBase: m6A_site_145044
mod ID: M6ASITE006310		Click to Show/Hide the Full List
mod site	chr11:62852922-62852923:-		[5]
Sequence	GAAGATTTGTTCCAGAAGGAACTGTCTGAGGGATGATAAAG
Motif Score	3.373380952
Cell/Tissue List	HeLa; A549; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000384756.1; ENST00000541615.5; ENST00000535076.5; ENST00000537068.5; ENST00000537925.5; ENST00000544550.5; ENST00000541578.5; ENST00000540725.5; ENST00000538266.5; ENST00000539975.5; ENST00000539921.5; ENST00000537869.5; ENST00000545688.5; ENST00000542112.5; ENST00000545440.5; ENST00000538654.5
External Link	RMBase: m6A_site_145045
mod ID: M6ASITE006311		Click to Show/Hide the Full List
mod site	chr11:62852961-62852962:-		[5]
Sequence	GTAAAGGTGAACCCACTGGGACTGGCTGGGGGAGAAGAGGA
Motif Score	4.065041667
Cell/Tissue List	HeLa; A549; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000535076.5; ENST00000541615.5; ENST00000545688.5; ENST00000539975.5; ENST00000541578.5; ENST00000538266.5; ENST00000544550.5; ENST00000545440.5; ENST00000537869.5; ENST00000542112.5; ENST00000538654.5; ENST00000384756.1; ENST00000537925.5; ENST00000537068.5; ENST00000539921.5; ENST00000540725.5
External Link	RMBase: m6A_site_145046
mod ID: M6ASITE006312		Click to Show/Hide the Full List
mod site	chr11:62852971-62852972:-		[5]
Sequence	CCCAGAGCCTGTAAAGGTGAACCCACTGGGACTGGCTGGGG
Motif Score	2.930744048
Cell/Tissue List	HeLa; A549; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000539921.5; ENST00000537925.5; ENST00000544550.5; ENST00000384756.1; ENST00000539975.5; ENST00000545688.5; ENST00000535076.5; ENST00000537068.5; ENST00000545440.5; ENST00000540725.5; ENST00000537869.5; ENST00000538266.5; ENST00000541615.5; ENST00000538654.5; ENST00000542112.5; ENST00000541578.5
External Link	RMBase: m6A_site_145047
mod ID: M6ASITE006313		Click to Show/Hide the Full List
mod site	chr11:62853015-62853016:-		[4]
Sequence	TTCCCAATGAAGAAACTTTCACATGTCTTACTCTCTGTCCT
Motif Score	2.047297619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000535076.5; ENST00000539921.5; ENST00000537068.5; ENST00000538266.5; ENST00000541578.5; ENST00000540725.5; ENST00000541615.5; ENST00000539975.5; ENST00000545688.5; ENST00000537925.5; ENST00000384756.1; ENST00000538654.5; ENST00000544550.5; ENST00000542112.5; ENST00000537869.5; ENST00000545440.5
External Link	RMBase: m6A_site_145048
mod ID: M6ASITE006314		Click to Show/Hide the Full List
mod site	chr11:62853021-62853022:-		[5]
Sequence	TAAAAATTCCCAATGAAGAAACTTTCACATGTCTTACTCTC
Motif Score	2.627720238
Cell/Tissue List	HeLa; A549; endometrial
Seq Type List	m6A-seq
Transcript ID List	ENST00000538266.5; ENST00000539975.5; ENST00000538654.5; ENST00000537068.5; ENST00000540725.5; ENST00000537869.5; ENST00000541578.5; ENST00000545440.5; ENST00000384756.1; ENST00000539921.5; ENST00000544550.5; ENST00000545688.5; ENST00000542112.5; ENST00000537925.5; ENST00000535076.5; ENST00000541615.5
External Link	RMBase: m6A_site_145049
mod ID: M6ASITE006315		Click to Show/Hide the Full List
mod site	chr11:62853048-62853049:-		[8]
Sequence	TAAACCTAAATGTAAGGTGGACTATGCTAAAAATTCCCAAT
Motif Score	4.065041667
Cell/Tissue List	A549
Seq Type List	m6A-seq
Transcript ID List	ENST00000544550.5; ENST00000541615.5; ENST00000537925.5; ENST00000538266.5; ENST00000540725.5; ENST00000538654.5; ENST00000545688.5; ENST00000545440.5; ENST00000535076.5; ENST00000537068.5; ENST00000542112.5; ENST00000539921.5; ENST00000539975.5; ENST00000537869.5; ENST00000541578.5
External Link	RMBase: m6A_site_145050
mod ID: M6ASITE006316		Click to Show/Hide the Full List
mod site	chr11:62853065-62853066:-		[8]
Sequence	CTGAAGTTACAGGTGAGTAAACCTAAATGTAAGGTGGACTA
Motif Score	2.185083333
Cell/Tissue List	A549
Seq Type List	m6A-seq
Transcript ID List	ENST00000535076.5; ENST00000537068.5; ENST00000541578.5; ENST00000542112.5; ENST00000540725.5; ENST00000544550.5; ENST00000539975.5; ENST00000545688.5; ENST00000539921.5; ENST00000537925.5; ENST00000538654.5; ENST00000537869.5; ENST00000545440.5; ENST00000538266.5; ENST00000541615.5
External Link	RMBase: m6A_site_145051
mod ID: M6ASITE006317		Click to Show/Hide the Full List
mod site	chr11:62853077-62853078:-		[7]
Sequence	GTTCACTCCAGGCTGAAGTTACAGGTGAGTAAACCTAAATG
Motif Score	2.07285119
Cell/Tissue List	HEK293
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000539975.5; ENST00000545440.5; ENST00000539921.5; ENST00000545688.5; ENST00000542112.5; ENST00000537925.5; ENST00000541615.5; ENST00000540865.5; ENST00000537869.5; ENST00000541578.5; ENST00000537068.5; ENST00000538654.5; ENST00000535076.5; ENST00000538266.5; ENST00000540725.5; ENST00000544550.5; ENST00000545920.1
External Link	RMBase: m6A_site_145052
mod ID: M6ASITE006318		Click to Show/Hide the Full List
mod site	chr11:62853189-62853190:-		[4]
Sequence	CTTTCTGCCAAGCAATAGATACAATTGAGAGATTGTAAAAT
Motif Score	2.110482143
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000545688.5; ENST00000541578.5; ENST00000540725.5; ENST00000539975.5; ENST00000544550.5; ENST00000542112.5; ENST00000537925.5; ENST00000540865.5; ENST00000537068.5; ENST00000539921.5; ENST00000541615.5; ENST00000545440.5; ENST00000535076.5; ENST00000545920.1; ENST00000538266.5; ENST00000537869.5; ENST00000538654.5
External Link	RMBase: m6A_site_145053
mod ID: M6ASITE006319		Click to Show/Hide the Full List
mod site	chr11:62853415-62853416:-		[9]
Sequence	CAAAGTCTTTGATCTCCTGAACCACCAGTGATGAATTGCTG
Motif Score	2.930744048
Cell/Tissue List	BGC823
Seq Type List	m6A-seq
Transcript ID List	ENST00000535076.5; ENST00000537068.5; ENST00000545440.5; ENST00000537869.5; ENST00000545920.1; ENST00000537925.5; ENST00000539975.5; ENST00000539921.5; ENST00000542112.5; ENST00000540725.5; ENST00000538266.5; ENST00000535689.5; ENST00000544550.5; ENST00000545688.5; ENST00000540865.5; ENST00000538654.5; ENST00000541578.5; ENST00000541615.5
External Link	RMBase: m6A_site_145054
mod ID: M6ASITE006320		Click to Show/Hide the Full List
mod site	chr11:62853452-62853453:-		[9]
Sequence	GTCTGGGTGAATGTACACAGACATAACTGGCTTAACCCAAA
Motif Score	2.897386905
Cell/Tissue List	BGC823
Seq Type List	m6A-seq
Transcript ID List	ENST00000538654.5; ENST00000538266.5; ENST00000545688.5; ENST00000537869.5; ENST00000535076.5; ENST00000540725.5; ENST00000537925.5; ENST00000544550.5; ENST00000542112.5; ENST00000545920.1; ENST00000545440.5; ENST00000535689.5; ENST00000541615.5; ENST00000537068.5; ENST00000540865.5; ENST00000539921.5; ENST00000539975.5; ENST00000541578.5
External Link	RMBase: m6A_site_145055
mod ID: M6ASITE006321		Click to Show/Hide the Full List
mod site	chr11:62853643-62853644:-		[9]
Sequence	TCTGAGAATGATGGGTGGGAACAACATAATGCGGGATATGA
Motif Score	2.951386905
Cell/Tissue List	BGC823
Seq Type List	m6A-seq
Transcript ID List	ENST00000542112.5; ENST00000539921.5; ENST00000537869.5; ENST00000538266.5; ENST00000540725.5; ENST00000545688.5; ENST00000535076.5; ENST00000538654.5; ENST00000541578.5; ENST00000541615.5; ENST00000540865.5; ENST00000545920.1; ENST00000544550.5; ENST00000539975.5; ENST00000537024.5; ENST00000535689.5; ENST00000537925.5; ENST00000539303.5; ENST00000537068.5; ENST00000545440.5
External Link	RMBase: m6A_site_145056
mod ID: M6ASITE006322		Click to Show/Hide the Full List
mod site	chr11:62853680-62853681:-		[9]
Sequence	GCTGATGACTTGCTGTTGAGACTCTGAAATCTGATTTTCTG
Motif Score	3.319380952
Cell/Tissue List	BGC823
Seq Type List	m6A-seq
Transcript ID List	ENST00000540725.5; ENST00000541578.5; ENST00000537925.5; ENST00000544550.5; ENST00000538654.5; ENST00000384693.1; ENST00000539303.5; ENST00000545920.1; ENST00000542112.5; ENST00000539975.5; ENST00000541615.5; ENST00000537869.5; ENST00000545440.5; ENST00000545688.5; ENST00000537068.5; ENST00000535689.5; ENST00000539921.5; ENST00000535076.5; ENST00000540865.5; ENST00000538266.5; ENST00000537024.5
External Link	RMBase: m6A_site_145057
mod ID: M6ASITE006323		Click to Show/Hide the Full List
mod site	chr11:62853717-62853718:-		[4]
Sequence	GCCTGTGTTTGTGATGACTTACATGGAATCTCGTTCGGCTG
Motif Score	2.07285119
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000538266.5; ENST00000542112.5; ENST00000540725.5; ENST00000537068.5; ENST00000535689.5; ENST00000541615.5; ENST00000537925.5; ENST00000538654.5; ENST00000545440.5; ENST00000540865.5; ENST00000544550.5; ENST00000539303.5; ENST00000545688.5; ENST00000545920.1; ENST00000539921.5; ENST00000541578.5; ENST00000539975.5; ENST00000384693.1; ENST00000537024.5; ENST00000537869.5
External Link	RMBase: m6A_site_145058
mod ID: M6ASITE006324		Click to Show/Hide the Full List
mod site	chr11:62853904-62853905:-		[5]
Sequence	AATACATGAACACCTGAGAAACTGGAGAACGCAGGGAGTGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; BGC823
Seq Type List	m6A-seq
Transcript ID List	ENST00000537068.5; ENST00000537925.5; ENST00000541615.5; ENST00000537869.5; ENST00000538266.5; ENST00000539921.5; ENST00000542112.5; ENST00000540865.5; ENST00000540725.5; ENST00000545920.1; ENST00000545440.5; ENST00000545688.5; ENST00000537024.5; ENST00000539303.5; ENST00000535689.5; ENST00000544550.5; ENST00000538654.5; ENST00000541578.5; ENST00000539975.5
External Link	RMBase: m6A_site_145059
mod ID: M6ASITE006325		Click to Show/Hide the Full List
mod site	chr11:62853915-62853916:-		[5]
Sequence	CCGACAGTGAAAATACATGAACACCTGAGAAACTGGAGAAC
Motif Score	2.951386905
Cell/Tissue List	HeLa; BGC823
Seq Type List	m6A-seq
Transcript ID List	ENST00000537024.5; ENST00000544550.5; ENST00000539975.5; ENST00000545688.5; ENST00000537925.5; ENST00000538654.5; ENST00000537869.5; ENST00000541615.5; ENST00000542112.5; ENST00000540865.5; ENST00000545920.1; ENST00000539303.5; ENST00000545440.5; ENST00000535689.5; ENST00000539921.5; ENST00000538266.5; ENST00000537068.5; ENST00000541578.5; ENST00000540725.5
External Link	RMBase: m6A_site_145060
mod ID: M6ASITE006326		Click to Show/Hide the Full List
mod site	chr11:62853932-62853933:-		[7]
Sequence	AAACTAGCTCACTATGACCGACAGTGAAAATACATGAACAC
Motif Score	2.865571429
Cell/Tissue List	HEK293
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000542112.5; ENST00000544550.5; ENST00000537869.5; ENST00000539303.5; ENST00000540865.5; ENST00000540725.5; ENST00000541578.5; ENST00000537068.5; ENST00000545440.5; ENST00000535689.5; ENST00000537925.5; ENST00000541615.5; ENST00000545920.1; ENST00000538266.5; ENST00000537024.5; ENST00000545688.5; ENST00000539921.5; ENST00000539975.5; ENST00000538654.5
External Link	RMBase: m6A_site_145061
mod ID: M6ASITE006327		Click to Show/Hide the Full List
mod site	chr11:62853950-62853951:-		[5]
Sequence	CAGTTTCTATGATGAATCAAACTAGCTCACTATGACCGACA
Motif Score	2.627720238
Cell/Tissue List	HeLa; BGC823; AML
Seq Type List	m6A-seq; miCLIP
Transcript ID List	ENST00000541615.5; ENST00000540865.5; ENST00000545440.5; ENST00000545920.1; ENST00000545688.5; ENST00000538266.5; ENST00000537068.5; ENST00000540725.5; ENST00000539921.5; ENST00000538654.5; ENST00000541578.5; ENST00000537925.5; ENST00000537024.5; ENST00000539303.5; ENST00000535689.5; ENST00000542112.5; ENST00000537869.5; ENST00000544550.5; ENST00000539975.5
External Link	RMBase: m6A_site_145062
mod ID: M6ASITE006328		Click to Show/Hide the Full List
mod site	chr11:62854163-62854164:-		[4]
Sequence	TCCATAAGGAATTGTCTGAGACATTTGGTTACCTTTTCTTA
Motif Score	2.897386905
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000544550.5; ENST00000539921.5; ENST00000545440.5; ENST00000539975.5; ENST00000539303.5; ENST00000538654.5; ENST00000537869.5; ENST00000516331.1; ENST00000537024.5; ENST00000545920.1; ENST00000541578.5; ENST00000535689.5; ENST00000540725.5; ENST00000537068.5; ENST00000538266.5; ENST00000541416.5; ENST00000537925.5; ENST00000541615.5; ENST00000540865.5; ENST00000542112.5; ENST00000545688.5
External Link	RMBase: m6A_site_145063
mod ID: M6ASITE006329		Click to Show/Hide the Full List
mod site	chr11:62854208-62854209:-		[4]
Sequence	TTGTGAACTCACCAGGGTTAACATGAAGAGGGCATGAGAGC
Motif Score	2.168095238
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000516331.1; ENST00000545440.5; ENST00000539303.5; ENST00000545688.5; ENST00000537068.5; ENST00000538654.5; ENST00000540725.5; ENST00000538266.5; ENST00000537869.5; ENST00000541615.5; ENST00000539921.5; ENST00000537925.5; ENST00000539975.5; ENST00000541578.5; ENST00000545920.1; ENST00000535689.5; ENST00000537024.5; ENST00000540865.5; ENST00000542112.5; ENST00000541416.5; ENST00000544550.5
External Link	RMBase: m6A_site_145064
mod ID: M6ASITE006330		Click to Show/Hide the Full List
mod site	chr11:62854268-62854269:-		[4]
Sequence	TCTGCTCCAATGAGGAGGAAACATCCTGCCTTACCCCTGTT
Motif Score	2.20572619
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000537869.5; ENST00000539975.5; ENST00000545440.5; ENST00000538654.5; ENST00000541615.5; ENST00000535689.5; ENST00000540865.5; ENST00000542112.5; ENST00000541578.5; ENST00000538266.5; ENST00000516331.1; ENST00000544550.5; ENST00000539921.5; ENST00000541416.5; ENST00000537024.5; ENST00000539303.5; ENST00000545688.5; ENST00000545920.1; ENST00000540725.5; ENST00000537925.5; ENST00000537068.5
External Link	RMBase: m6A_site_145065
mod ID: M6ASITE006331		Click to Show/Hide the Full List
mod site	chr11:62854967-62854968:-		[4]
Sequence	TTGAATGACTATTTTTAGGTACATAAAATGCTTTCCTCTGT
Motif Score	2.856142857
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000544983.1; ENST00000537068.5; ENST00000541578.5; ENST00000537869.5; ENST00000539303.5; ENST00000545440.5; ENST00000544550.5; ENST00000541416.5; ENST00000535689.5; ENST00000540865.5; ENST00000537965.5; ENST00000540725.5; ENST00000539921.5; ENST00000540904.1; ENST00000545688.5; ENST00000538654.5; ENST00000538266.5; ENST00000541615.5; ENST00000537925.5; ENST00000542112.5; ENST00000539975.5; ENST00000537024.5; ENST00000545308.5
External Link	RMBase: m6A_site_145066
mod ID: M6ASITE006332		Click to Show/Hide the Full List
mod site	chr11:62855044-62855045:-		[5]
Sequence	AATGACAAGCATATGGCTGAACTTTCAAGTGATGTCATCTT
Motif Score	3.373380952
Cell/Tissue List	HeLa; AML
Seq Type List	m6A-seq; miCLIP
Transcript ID List	ENST00000539303.5; ENST00000540904.1; ENST00000544983.1; ENST00000539975.5; ENST00000538266.5; ENST00000537925.5; ENST00000545688.5; ENST00000537869.5; ENST00000541615.5; ENST00000540725.5; ENST00000535689.5; ENST00000537965.5; ENST00000540865.5; ENST00000541578.5; ENST00000541416.5; ENST00000545308.5; ENST00000544550.5; ENST00000542112.5; ENST00000363981.1; ENST00000537024.5; ENST00000537068.5; ENST00000539921.5; ENST00000545440.5; ENST00000538654.5
External Link	RMBase: m6A_site_145067
mod ID: M6ASITE006333		Click to Show/Hide the Full List
mod site	chr11:62855060-62855061:-		[4]
Sequence	TCCATGATGAACACAAAATGACAAGCATATGGCTGAACTTT
Motif Score	2.859755952
Cell/Tissue List	hESC-HEK293T
Seq Type List	MAZTER-seq
Transcript ID List	ENST00000535689.5; ENST00000542112.5; ENST00000538654.5; ENST00000540725.5; ENST00000537965.5; ENST00000539921.5; ENST00000538266.5; ENST00000544983.1; ENST00000545308.5; ENST00000541416.5; ENST00000541578.5; ENST00000537068.5; ENST00000539303.5; ENST00000540904.1; ENST00000537869.5; ENST00000539975.5; ENST00000544550.5; ENST00000363981.1; ENST00000545440.5; ENST00000537024.5; ENST00000537925.5; ENST00000540865.5; ENST00000541615.5; ENST00000545688.5
External Link	RMBase: m6A_site_145068
mod ID: M6ASITE006334		Click to Show/Hide the Full List
mod site	chr11:62855204-62855205:-		[7]
Sequence	TTTTTTCAGATGTTCAGCCCACAAGAGCTTACTGGTGAAGG
Motif Score	2.053113095
Cell/Tissue List	HEK293
Seq Type List	m6A-REF-seq
Transcript ID List	ENST00000544550.5; ENST00000545308.5; ENST00000545688.5; ENST00000537869.5; ENST00000541578.5; ENST00000540904.1; ENST00000545440.5; ENST00000541416.5; ENST00000544983.1; ENST00000537024.5; ENST00000541615.5; ENST00000535689.5; ENST00000537965.5; ENST00000542112.5; ENST00000537925.5; ENST00000538266.5; ENST00000540725.5; ENST00000538654.5; ENST00000539921.5; ENST00000540865.5; ENST00000539975.5; ENST00000537068.5
External Link	RMBase: m6A_site_145069
mod ID: M6ASITE006335		Click to Show/Hide the Full List
mod site	chr11:62855309-62855310:-		[5]
Sequence	CTGATGGATTAGTGGAGAAAACAGAAAATTCTGAGTAGCAC
Motif Score	2.20572619
Cell/Tissue List	HeLa; BGC823
Seq Type List	m6A-seq
Transcript ID List	ENST00000540904.1; ENST00000541615.5; ENST00000545308.5; ENST00000538654.5; ENST00000384147.1; ENST00000544983.1; ENST00000538266.5; ENST00000540865.5; ENST00000537068.5; ENST00000535689.5; ENST00000537965.5; ENST00000540725.5; ENST00000537024.5; ENST00000537925.5; ENST00000541416.5; ENST00000545440.5; ENST00000545688.5; ENST00000544550.5; ENST00000537869.5; ENST00000541578.5; ENST00000542112.5
External Link	RMBase: m6A_site_145070
mod ID: M6ASITE006336		Click to Show/Hide the Full List
mod site	chr11:62855340-62855341:-		[5]
Sequence	GGGATGATTTTACGAACTGAACTCTCTCTTTCTGATGGATT
Motif Score	3.373380952
Cell/Tissue List	HeLa; BGC823
Seq Type List	m6A-seq
Transcript ID List	ENST00000538654.5; ENST00000537965.5; ENST00000542112.5; ENST00000541615.5; ENST00000541416.5; ENST00000544983.1; ENST00000384147.1; ENST00000540865.5; ENST00000535689.5; ENST00000537068.5; ENST00000540904.1; ENST00000537869.5; ENST00000541578.5; ENST00000537925.5; ENST00000545440.5; ENST00000545308.5; ENST00000540725.5; ENST00000537024.5; ENST00000544550.5; ENST00000538266.5; ENST00000545688.5
External Link	RMBase: m6A_site_145071
mod ID: M6ASITE006337		Click to Show/Hide the Full List
mod site	chr11:62855345-62855346:-		[5]
Sequence	CTACGGGGATGATTTTACGAACTGAACTCTCTCTTTCTGAT
Motif Score	3.373380952
Cell/Tissue List	HeLa; BGC823; AML
Seq Type List	m6A-seq; miCLIP
Transcript ID List	ENST00000537024.5; ENST00000545308.5; ENST00000537925.5; ENST00000538266.5; ENST00000537068.5; ENST00000541578.5; ENST00000540865.5; ENST00000544550.5; ENST00000384147.1; ENST00000544983.1; ENST00000540725.5; ENST00000541416.5; ENST00000537965.5; ENST00000538654.5; ENST00000540904.1; ENST00000537869.5; ENST00000535689.5; ENST00000545440.5; ENST00000545688.5; ENST00000541615.5; ENST00000542112.5
External Link	RMBase: m6A_site_145072
mod ID: M6ASITE006338		Click to Show/Hide the Full List
mod site	chr11:62855446-62855447:-		[5]
Sequence	GGATTTACGCGCACGTTGGAACCGAAGAGAGCTCTGTTGTT
Motif Score	2.930744048
Cell/Tissue List	HeLa; BGC823
Seq Type List	m6A-seq
Transcript ID List	ENST00000537925.5; ENST00000538266.5; ENST00000541615.5; ENST00000535689.5; ENST00000540904.1; ENST00000545440.5; ENST00000538654.5; ENST00000544983.1; ENST00000545308.5; ENST00000537024.5; ENST00000540865.5; ENST00000537869.5; ENST00000542112.5; ENST00000541416.5; ENST00000545688.5; ENST00000537965.5; ENST00000544550.5; ENST00000540725.5; ENST00000537068.5; ENST00000541578.5
External Link	RMBase: m6A_site_145073
mod ID: M6ASITE006339		Click to Show/Hide the Full List
mod site	chr11:62855604-62855605:-		[9]
Sequence	TGATGAGGACCTTTTCACAGACCTGTACTGAGCTCCGTGAG
Motif Score	2.876744048
Cell/Tissue List	BGC823
Seq Type List	m6A-seq
Transcript ID List	ENST00000541416.5; ENST00000537068.5; ENST00000544983.1; ENST00000540725.5; ENST00000537925.5; ENST00000538654.5; ENST00000542112.5; ENST00000365607.2
External Link	RMBase: m6A_site_145074
mod ID: M6ASITE006340		Click to Show/Hide the Full List
mod site	chr11:62855616-62855617:-		[9]
Sequence	TCCCCCTTCCTATGATGAGGACCTTTTCACAGACCTGTACT
Motif Score	3.622404762
Cell/Tissue List	BGC823
Seq Type List	m6A-seq
Transcript ID List	ENST00000541416.5; ENST00000544983.1; ENST00000537068.5; ENST00000537925.5; ENST00000365607.2; ENST00000542112.5; ENST00000538654.5; ENST00000540725.5
External Link	RMBase: m6A_site_145075
mod ID: M6ASITE006341		Click to Show/Hide the Full List
mod site	chr11:62855664-62855665:-		[4]
Sequence	GCAGTGGGGCTTTGTGAAGGACAAAATGGCGATGGCGGGCC
Motif Score	3.643047619
Cell/Tissue List	hESC-HEK293T; BGC823
Seq Type List	MAZTER-seq; m6A-seq
Transcript ID List	ENST00000544983.1; ENST00000538654.5; ENST00000540725.5; ENST00000537925.5; ENST00000541416.5; ENST00000537068.5; ENST00000542112.5
External Link	RMBase: m6A_site_145076
mod ID: M6ASITE006342		Click to Show/Hide the Full List
mod site	chr11:62855781-62855782:-		[5]
Sequence	TCTTTTGAGCGATTGTGCGAACATAGCATAGCACGCACTAT
Motif Score	2.951386905
Cell/Tissue List	HeLa; hESC-HEK293T; MT4
Seq Type List	m6A-seq; MAZTER-seq; MeRIP-seq
Transcript ID List	ENST00000537068.5; ENST00000541416.5; ENST00000542112.5; ENST00000537925.5; ENST00000538654.5
External Link	RMBase: m6A_site_145077

Ref 1	Comprehensive Pan-Cancer Analysis of the Prognostic and Immunological Roles of the METTL3/lncRNA-SNHG1/miRNA-140-3p/UBE2C Axis. Front Cell Dev Biol. 2021 Nov 10;9:765772. doi: 10.3389/fcell.2021.765772. eCollection 2021.
Ref 2	Diabetes-enhanced tumor necrosis factor-alpha production promotes apoptosis and the loss of retinal microvascular cells in type 1 and type 2 models of diabetic retinopathy. Am J Pathol. 2008 May;172(5):1411-8. doi: 10.2353/ajpath.2008.071070. Epub 2008 Apr 10.
Ref 3	Nm-seq maps 2'-O-methylation sites in human mRNA with base precision. Nat Methods. 2017 Jul;14(7):695-698. doi: 10.1038/nmeth.4294. Epub 2017 May 15.
Ref 4	Deciphering the "m(6)A Code" via Antibody-Independent Quantitative Profiling. Cell. 2019 Jul 25;178(3):731-747.e16. doi: 10.1016/j.cell.2019.06.013. Epub 2019 Jun 27.
Ref 5	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 6	DART-seq: an antibody-free method for global m(6)A detection. Nat Methods. 2019 Dec;16(12):1275-1280. doi: 10.1038/s41592-019-0570-0. Epub 2019 Sep 23.
Ref 7	Single-base mapping of m(6)A by an antibody-independent method. Sci Adv. 2019 Jul 3;5(7):eaax0250. doi: 10.1126/sciadv.aax0250. eCollection 2019 Jul.
Ref 8	Perturbation of m6A writers reveals two distinct classes of mRNA methylation at internal and 5' sites. Cell Rep. 2014 Jul 10;8(1):284-96. doi: 10.1016/j.celrep.2014.05.048. Epub 2014 Jun 26.
Ref 9	METTL3-mediated N6-methyladenosine modification is critical for epithelial-mesenchymal transition and metastasis of gastric cancer. Mol Cancer. 2019 Oct 13;18(1):142. doi: 10.1186/s12943-019-1065-4.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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