m6A Target Gene Information

General Information of the m6A Target Gene (ID: M6ATAR00093)

Target Name	Long intergenic non-protein coding RNA 857 (LINC00857)
Synonyms	LINC00857; HUMT; lncRNA highly upregulated in metastatic TNBC-lymph node Click to Show/Hide
Gene Name	LINC00857
Chromosomal Location	10q22.3
Family	Long intergenic non-protein coding RNAs
Gene ID	439990
HGNC ID	HGNC:45114

Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)

LINC00857 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).

Browse Disease

Pancreatic cancer [ICD-11: 2C10]

Disease Info

In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response		[]
Response Summary	LINC00857/miR-150-5p/E2F3 regulatory axis is taken as an alternative therapeutic target for treating pancreatic Cancer.
Responsed Disease	Pancreatic cancer [ICD-11: 2C10]
Cell Process	RNA stability
	Cell apoptosis
In-vitro Model	()
	()
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RNA Modification Sequencing Data Associated with the Target (ID: M6ATAR00093)

Long intergenic non-protein coding RNA 857 (LINC00857)

N6-methyladenosine (m6A)

In total 29 m6A sequence/site(s) in this target gene
mod ID: M6ASITE001053		Click to Show/Hide the Full List
mod site	chr10:80207904-80207905:+		[1]
Sequence	CCTTTTATAATTTTCAACAAACCTGCGTTTAGCCCCGGCTA
Motif Score	2.185083333
Cell/Tissue List	HeLa; HepG2; A549; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1
External Link	RMBase: m6A_site_108119
mod ID: M6ASITE001055		Click to Show/Hide the Full List
mod site	chr10:80207946-80207947:+		[1]
Sequence	GTGCCAGCAAGTTGCTAGGGACTGAGGAGGCTCTGCAGAGG
Motif Score	4.065041667
Cell/Tissue List	HeLa; A549; HepG2; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq; m6A-CLIP/IP
Transcript ID List	ENST00000422847.1
External Link	RMBase: m6A_site_108120
mod ID: M6ASITE001056		Click to Show/Hide the Full List
mod site	chr10:80207967-80207968:+		[1]
Sequence	CTGAGGAGGCTCTGCAGAGGACCCGAGCTGAGGCCCTAATC
Motif Score	3.622404762
Cell/Tissue List	HeLa; A549; HepG2; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1
External Link	RMBase: m6A_site_108121
mod ID: M6ASITE001057		Click to Show/Hide the Full List
mod site	chr10:80208051-80208052:+		[1]
Sequence	AACGCGGTGTGAAGGAAAAGACACCAAACTCGGTGTTCAAA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; U2OS; HEK293A-TOA; iSLK; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	rmsk_3359083; ENST00000422847.1
External Link	RMBase: m6A_site_108122
mod ID: M6ASITE001058		Click to Show/Hide the Full List
mod site	chr10:80208058-80208059:+		[1]
Sequence	TGTGAAGGAAAAGACACCAAACTCGGTGTTCAAATGTGTGG
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; U2OS; HEK293A-TOA; iSLK; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	rmsk_3359083; ENST00000422847.1
External Link	RMBase: m6A_site_108123
mod ID: M6ASITE001059		Click to Show/Hide the Full List
mod site	chr10:80208219-80208220:+		[1]
Sequence	GTTTCCCAGGGCTCATAGAAACATCATACAAGGTAAGGGAA
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T; A549; U2OS; Huh7; HEK293A-TOA; iSLK; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1; rmsk_3359083; ENST00000432308.1
External Link	RMBase: m6A_site_108124
mod ID: M6ASITE001060		Click to Show/Hide the Full List
mod site	chr10:80218041-80218042:+		[1]
Sequence	GAGAAGAGTACCCAAGAAGGACAAGCTTGGAATGGGGCCCC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; A549; U2OS; Huh7; HEK293A-TOA; iSLK; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000432308.1; ENST00000422847.1
External Link	RMBase: m6A_site_108125
mod ID: M6ASITE001061		Click to Show/Hide the Full List
mod site	chr10:80218082-80218083:+		[1]
Sequence	CTCCCCAGGCTGGAGATCAGACATTGTTGGAGAAGGTATCA
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; U2OS; Huh7; HEK293A-TOA; iSLK; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000432308.1; ENST00000422847.1
External Link	RMBase: m6A_site_108126
mod ID: M6ASITE001062		Click to Show/Hide the Full List
mod site	chr10:80218170-80218171:+		[1]
Sequence	GAGCTGGTTGCAATTATTGGACAAGCAGGAAACAAACCTCC
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; A549; Huh7; HEK293A-TOA; iSLK; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000432308.1; ENST00000422847.1
External Link	RMBase: m6A_site_108127
mod ID: M6ASITE001063		Click to Show/Hide the Full List
mod site	chr10:80218181-80218182:+		[1]
Sequence	AATTATTGGACAAGCAGGAAACAAACCTCCACAGCCCATGC
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T; A549; Huh7; HEK293A-TOA; iSLK; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1; ENST00000432308.1
External Link	RMBase: m6A_site_108128
mod ID: M6ASITE001064		Click to Show/Hide the Full List
mod site	chr10:80218260-80218261:+		[1]
Sequence	TGATTGGGTCTCCAGTGCGGACAGAAGGCATGGATCGCGTG
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; A549; Huh7; HEK293A-TOA; iSLK; MSC
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1; ENST00000432308.1
External Link	RMBase: m6A_site_108129
mod ID: M6ASITE001066		Click to Show/Hide the Full List
mod site	chr10:80218326-80218327:+		[1]
Sequence	AGGGCGATCACCATGCCAGGACAAGACTAGTTGCCTGGGAT
Motif Score	3.643047619
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; U2OS; fibroblasts; H1299; Huh7; HEK293A-TOA; iSLK; MSC; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1; ENST00000432308.1
External Link	RMBase: m6A_site_108130
mod ID: M6ASITE001067		Click to Show/Hide the Full List
mod site	chr10:80218331-80218332:+		[1]
Sequence	GATCACCATGCCAGGACAAGACTAGTTGCCTGGGATCTTCT
Motif Score	3.319380952
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; U2OS; fibroblasts; H1299; Huh7; HEK293A-TOA; iSLK; MSC; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1; ENST00000432308.1
External Link	RMBase: m6A_site_108131
mod ID: M6ASITE001068		Click to Show/Hide the Full List
mod site	chr10:80218401-80218402:+		[1]
Sequence	GATCTCCTCACACCAGCCAGACCCAGGAAGAGAAGCTCCTT
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; A549; HepG2; U2OS; H1B; fibroblasts; H1299; Huh7; HEK293A-TOA; iSLK; MSC; endometrial; HEC-1-A
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000432308.1; ENST00000422847.1
External Link	RMBase: m6A_site_108132
mod ID: M6ASITE001069		Click to Show/Hide the Full List
mod site	chr10:80218609-80218610:+		[2]
Sequence	ATATTTGAAGAACGCTGTGAACACATATGCATGGGTCCATG
Motif Score	2.951386905
Cell/Tissue List	A549
Seq Type List	MeRIP-seq
Transcript ID List	ENST00000422847.1; ENST00000432308.1
External Link	RMBase: m6A_site_108133
mod ID: M6ASITE001070		Click to Show/Hide the Full List
mod site	chr10:80219202-80219203:+		[1]
Sequence	CATTCCTGGGCGTAGGCTGAACTAACTTTGGGAGAAACTTA
Motif Score	3.373380952
Cell/Tissue List	HeLa; HEK293T; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1; rmsk_3359114
External Link	RMBase: m6A_site_108134
mod ID: M6ASITE001071		Click to Show/Hide the Full List
mod site	chr10:80219218-80219219:+		[1]
Sequence	CTGAACTAACTTTGGGAGAAACTTAGTTTGTAGTTATAGTT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293T; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	rmsk_3359114; ENST00000422847.1
External Link	RMBase: m6A_site_108135
mod ID: M6ASITE001072		Click to Show/Hide the Full List
mod site	chr10:80219242-80219243:+		[1]
Sequence	AGTTTGTAGTTATAGTTTAAACAAAGACTGTGACAGCCCTT
Motif Score	2.20572619
Cell/Tissue List	HeLa; HEK293T; A549; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1; rmsk_3359114
External Link	RMBase: m6A_site_108136
mod ID: M6ASITE001073		Click to Show/Hide the Full List
mod site	chr10:80219248-80219249:+		[1]
Sequence	TAGTTATAGTTTAAACAAAGACTGTGACAGCCCTTTCCCAA
Motif Score	3.319380952
Cell/Tissue List	HeLa; HEK293T; A549; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1; rmsk_3359114
External Link	RMBase: m6A_site_108137
mod ID: M6ASITE001074		Click to Show/Hide the Full List
mod site	chr10:80219274-80219275:+		[1]
Sequence	ACAGCCCTTTCCCAATGCAGACCTCCTTCTTGTCTGGGGAC
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293T; A549; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1; rmsk_3359114
External Link	RMBase: m6A_site_108138
mod ID: M6ASITE001075		Click to Show/Hide the Full List
mod site	chr10:80219293-80219294:+		[1]
Sequence	GACCTCCTTCTTGTCTGGGGACTAGACTAACATTAGCCACA
Motif Score	4.065041667
Cell/Tissue List	HeLa; HEK293T; A549; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	rmsk_3359114; ENST00000422847.1
External Link	RMBase: m6A_site_108139
mod ID: M6ASITE001077		Click to Show/Hide the Full List
mod site	chr10:80219298-80219299:+		[1]
Sequence	CCTTCTTGTCTGGGGACTAGACTAACATTAGCCACAGGATT
Motif Score	3.319380952
Cell/Tissue List	HeLa; HEK293T; A549; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	rmsk_3359114; ENST00000422847.1
External Link	RMBase: m6A_site_108140
mod ID: M6ASITE001078		Click to Show/Hide the Full List
mod site	chr10:80219377-80219378:+		[1]
Sequence	AAGATTCTGACCCTCCCTAAACTGCTTCTAAGATCAGTGCT
Motif Score	2.627720238
Cell/Tissue List	HeLa; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000422847.1; rmsk_3359114
External Link	RMBase: m6A_site_108141
mod ID: M6ASITE001079		Click to Show/Hide the Full List
mod site	chr10:80219402-80219403:+		[1]
Sequence	TTCTAAGATCAGTGCTTGAGACATGTTGCAGACCCCGCACT
Motif Score	2.897386905
Cell/Tissue List	HeLa; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	rmsk_3359114; ENST00000422847.1
External Link	RMBase: m6A_site_108142
mod ID: M6ASITE001080		Click to Show/Hide the Full List
mod site	chr10:80219413-80219414:+		[1]
Sequence	GTGCTTGAGACATGTTGCAGACCCCGCACTTGCTGGATCAG
Motif Score	2.876744048
Cell/Tissue List	HeLa; HEK293A-TOA
Seq Type List	m6A-seq
Transcript ID List	ENST00000422847.1; rmsk_3359114
External Link	RMBase: m6A_site_108143
mod ID: M6ASITE001081		Click to Show/Hide the Full List
mod site	chr10:80219456-80219457:+		[1]
Sequence	GACGCCACACAGATGGATAAACTGCCTCGTCTGATCTTGTG
Motif Score	2.627720238
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1; rmsk_3359114
External Link	RMBase: m6A_site_108144
mod ID: M6ASITE001082		Click to Show/Hide the Full List
mod site	chr10:80219491-80219492:+		[1]
Sequence	CTTGTGGCCCCCACCCGGGAACTGACGAAGCGCAAGAAGAC
Motif Score	3.373380952
Cell/Tissue List	HeLa; Huh7; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	rmsk_3359114; ENST00000422847.1
External Link	RMBase: m6A_site_108145
mod ID: M6ASITE001083		Click to Show/Hide the Full List
mod site	chr10:80219510-80219511:+		[1]
Sequence	AACTGACGAAGCGCAAGAAGACAGCTTCGACTCCCTGTGAG
Motif Score	2.897386905
Cell/Tissue List	HeLa; Huh7; HEK293A-TOA
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1; rmsk_3359114
External Link	RMBase: m6A_site_108146
mod ID: M6ASITE001084		Click to Show/Hide the Full List
mod site	chr10:80219620-80219621:+		[1]
Sequence	CTCCCCGAATTCTCGAGGAGACTGATTTGAGTGATAATAAA
Motif Score	3.319380952
Cell/Tissue List	HeLa; Huh7
Seq Type List	m6A-seq; MeRIP-seq
Transcript ID List	ENST00000422847.1; rmsk_3359114
External Link	RMBase: m6A_site_108147

Ref 1	VIRMA mediates preferential m(6)A mRNA methylation in 3'UTR and near stop codon and associates with alternative polyadenylation. Cell Discov. 2018 Feb 27;4:10. doi: 10.1038/s41421-018-0019-0. eCollection 2018.
Ref 2	Viral N(6)-methyladenosine upregulates replication and pathogenesis of human respiratory syncytial virus. Nat Commun. 2019 Oct 9;10(1):4595. doi: 10.1038/s41467-019-12504-y.

m6A Target Gene Information

Cite M6AREG

Correspondence

Prof. Feng ZHU

Prof. Shuiping Liu

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