m6A Target Gene Information
General Information of the m6A Target Gene (ID: M6ATAR00046)
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
hsa-miR-320d
can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
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Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) [READER]
| In total 1 item(s) under this regulator | ||||
| Experiment 1 Reporting the m6A Methylation Regulator of This Target Gene | [1] | |||
| Response Summary | HNRNPC, YTHDF, ZC3H13, YTHDC2, and METTL14 were dysregulated in esophageal cancer tissues. miR-186 interacted with HNRNPC and suppressed the expression of HNRNPC. Four miRNAs (miR-186, miR-320c, hsa-miR-320d, and miR-320b) were used to construct a prognostic signature, which could serve as a prognostic predictor independent from routine clinicopathological features. | |||
| Responsed Disease | Esophageal cancer | ICD-11: 2B70 | ||
| In-vitro Model | HEEC cell line (Normal esophageal epithelial cell line) | |||
| KYSE-30 | Esophageal squamous cell carcinoma | Homo sapiens | CVCL_1351 | |
| TE-1 | Esophageal squamous cell carcinoma | Homo sapiens | CVCL_1759 | |
Esophageal cancer [ICD-11: 2B70]
| In total 1 item(s) under this disease | ||||
| Experiment 1 Reporting the m6A-centered Disease Response | [1] | |||
| Response Summary | HNRNPC, YTHDF, ZC3H13, YTHDC2, and METTL14 were dysregulated in esophageal cancer tissues. miR-186 interacted with HNRNPC and suppressed the expression of HNRNPC. Four miRNAs (miR-186, miR-320c, hsa-miR-320d, and miR-320b) were used to construct a prognostic signature, which could serve as a prognostic predictor independent from routine clinicopathological features. | |||
| Responsed Disease | Esophageal cancer [ICD-11: 2B70] | |||
| Target Regulator | Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC) | READER | ||
| In-vitro Model | HEEC cell line (Normal esophageal epithelial cell line) | |||
| KYSE-30 | Esophageal squamous cell carcinoma | Homo sapiens | CVCL_1351 | |
| TE-1 | Esophageal squamous cell carcinoma | Homo sapiens | CVCL_1759 | |
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Regulator
Non-coding RNA
m6A Regulator: Heterogeneous nuclear ribonucleoproteins C1/C2 (HNRNPC)
| In total 1 item(s) under this m6A regulator | ||
| Crosstalk ID: M6ACROT05508 | ||
| Epigenetic Regulator | hsa-miR-320d | |
| Regulated Target | Heterogeneous nuclear ribonucleoprotein C (HNRNPC) | |
| Crosstalk relationship | m6A → ncRNA | |
| Disease | Esophageal cancer | |