General Information of the m6A Target Gene (ID: M6ATAR00008)
Target Name Circ_E7
Gene Name Circ_E7
Full List of m6A Methylation Regulator of This Target Gene and Corresponding Disease/Drug Response(s)
Circ_E7 can be regulated by the following regulator(s), and cause disease/drug response(s). You can browse detail information of regulator(s) or disease/drug response(s).
Browse Disease
Papillomaviruses [ICD-11: 1D9Z]
In total 1 item(s) under this disease
Experiment 1 Reporting the m6A-centered Disease Response []
Response Summary Oncogenic human papillomaviruses (HPVs) generate circRNAs, some of which encompass the E7 oncogene (circE7). Circ_E7 is N6-methyladenosine (m6A) modified, preferentially localized to the cytoplasm, associated with polysomes, and translated to produce E7 oncoprotein.
Responsed Disease Papillomaviruses [ICD-11: 1D9Z]
Cell Process RNA metabolism
In-vitro Model ()
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In-vivo Model Mice were anesthetized and shaved on both flanks and injected subcutaneously with 4 × 106 tumor cells in 200 uL of PBS.