Results indicating the target gene (PEDF ) expression regulated by m6A regulator (METTL3 )
2B33: Malignant haematopoietic neoplasm
In total 1 results
Result 1 indicating the PEDF expression regulated by METTL3
Cell Line Raw 264.7 cell line CVCL_0493
Condition Leukemia Mus musculus
Treatment: METTL3 knockout Raw 264.7 cells
Control: Wild type Raw 264.7 cells
GSE162248
Regulation
logFC: -1.76E+00
p-value: 4.94E-06
2B91: Colorectal cancer
In total 1 results
Result 1 indicating the PEDF expression regulated by METTL3
Cell Line Caco-2 cell line CVCL_0025
Condition Colorectal adenocarcinoma Homo sapiens
Treatment: shMETTL3 Caco-2 cells
Control: shNTC Caco-2 cells
GSE167075
Regulation
logFC: -9.30E-01
p-value: 1.13E-16
Healthy
In total 7 results
Result 1 indicating the PEDF expression regulated by METTL3
Cell Line Pancreatic islets
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mice
Control: Mettl3 flox/flox mice
GSE155612
Regulation
logFC: 9.63E-01
p-value: 1.67E-02
Result 2 indicating the PEDF expression regulated by METTL3
Cell Line ARPE-19 cell line CVCL_0145
Condition Healthy Homo sapiens
Treatment: shMETTL3 ARPE-19 cells
Control: shControl ARPE-19 cells
GSE202017
Regulation
logFC: -2.90E+00
p-value: 2.60E-09
Result 3 indicating the PEDF expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- mESCs
Control: Wild type ESCs
GSE147849
Regulation
logFC: 3.66E+00
p-value: 9.37E-18
Result 4 indicating the PEDF expression regulated by METTL3
Cell Line Tfh cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Tfh cells
Control: Wild type splenic Tfh cells
GSE129648
Regulation
logFC: -3.74E+00
p-value: 1.19E-12
Result 5 indicating the PEDF expression regulated by METTL3
Cell Line E14.5 LSK cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout E14.5 LSK cells
Control: Wild type E14.5 LSK cells
GSE148882
Regulation
logFC: -1.06E+00
p-value: 5.51E-10
Result 6 indicating the PEDF expression regulated by METTL3
Cell Line Embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3 knockout mESCs
Control: Wild type mESCs
GSE156481
Regulation
logFC: 1.38E+00
p-value: 1.99E-09
Result 7 indicating the PEDF expression regulated by METTL3
Cell Line mouse embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- ESCs
Control: Wild type ESCs
GSE145309
Regulation
logFC: 1.40E+00
p-value: 3.93E-04