Results indicating the target gene (CD274 ) expression regulated by m6A regulator (METTL3 )
2B33: Malignant haematopoietic neoplasm
In total 1 results
Result 1 indicating the CD274 expression regulated by METTL3
Cell Line Raw 264.7 cell line CVCL_0493
Condition Leukemia Mus musculus
Treatment: METTL3 knockout Raw 264.7 cells
Control: Wild type Raw 264.7 cells
GSE162248
Regulation
logFC: -1.32E+00
p-value: 1.08E-20
2B90: Colon cancer
In total 1 results
Result 1 indicating the CD274 expression regulated by METTL3
Cell Line CT26 cell line CVCL_7254
Condition Colon adenocarcinoma Mus musculus
Treatment: METTL3 knockout CT26 cells
Control: CT26 cells
GSE142589
Regulation
logFC: 1.30E+00
p-value: 1.96E-05
2B91: Colorectal cancer
In total 1 results
Result 1 indicating the CD274 expression regulated by METTL3
Cell Line DKO-1 cell line CVCL_9798
Condition Colorectal cancer Homo sapiens
Treatment: METTL3 knockdown DKO-1 cell
Control: DKO-1 cell
GSE182382
Regulation
logFC: 8.58E-01
p-value: 7.05E-03
Healthy
In total 8 results
Result 1 indicating the CD274 expression regulated by METTL3
Cell Line Liver
Condition Healthy Mus musculus
Treatment: Mettl3 knockout liver
Control: Wild type liver cells
GSE198513
Regulation
logFC: 7.53E-01
p-value: 7.16E-05
Result 2 indicating the CD274 expression regulated by METTL3
Cell Line Pancreatic islets
Condition Healthy Mus musculus
Treatment: Mettl3 knockout mice
Control: Mettl3 flox/flox mice
GSE155612
Regulation
logFC: 7.65E-01
p-value: 1.54E-02
Result 3 indicating the CD274 expression regulated by METTL3
Cell Line LX2 cell line CVCL_5792
Condition Healthy Homo sapiens
Treatment: shMETTL3 LX2 cells
Control: shLuc LX2 cells
GSE207909
Regulation
logFC: -1.82E+00
p-value: 4.68E-65
Result 4 indicating the CD274 expression regulated by METTL3
Cell Line ARPE-19 cell line CVCL_0145
Condition Healthy Homo sapiens
Treatment: shMETTL3 ARPE-19 cells
Control: shControl ARPE-19 cells
GSE202017
Regulation
logFC: -2.69E+00
p-value: 2.99E-08
Result 5 indicating the CD274 expression regulated by METTL3
Cell Line HUVEC cell line
Condition Healthy Homo sapiens
Treatment: shMETTL3 HUVEC cells
Control: shScramble HUVEC cells
GSE157544
Regulation
logFC: -5.98E-01
p-value: 2.23E-02
Result 6 indicating the CD274 expression regulated by METTL3
Cell Line Th1 cell line CVCL_5J51
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Th1 cells
Control: Wild type splenic Th1 cells
GSE129648
Regulation
logFC: 1.80E+00
p-value: 3.15E-17
Result 7 indicating the CD274 expression regulated by METTL3
Cell Line mouse embryonic stem cells
Condition Healthy Mus musculus
Treatment: METTL3-/- ESCs
Control: Wild type ESCs
GSE145309
Regulation
logFC: 2.23E+00
p-value: 3.34E-07
Result 8 indicating the CD274 expression regulated by METTL3
Cell Line Tfh cell line
Condition Healthy Mus musculus
Treatment: METTL3 knockout splenic Tfh cells
Control: Wild type splenic Tfh cells
GSE129648
Regulation
logFC: 8.24E-01
p-value: 5.52E-04