m6A-centered Drug Response Information
General Information of the Drug (ID: M6ADRUG0232)
| Name |
Trimethoprim
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| Synonyms |
AcSDKP; Seraspenide; BIM-32001; Acetyl-seryl-aspartyl-lysyl-proline
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| Structure |
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3D MOL
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| Formula |
C14H18N4O3
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| InChI |
1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)
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| InChIKey |
IEDVJHCEMCRBQM-UHFFFAOYSA-N
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Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Drug
| In total 1 item(s) under this drug | ||
| Crosstalk ID: M6ACROT00123 | ||
| m6A Regulator | Methyltransferase-like 3 (METTL3) | |
| m6A Target | Interferon-inducible protein 4 (ADAR1) | |
| Epigenetic Regulator | Interferon-inducible protein 4 (ADAR1) | |
| Regulated Target | Dihydrofolate reductase (DHFR) | |
| Crosstalk relationship | m6A → A-to-I | |