m6A-centered Drug Response Information
General Information of the Drug (ID: M6ADRUG0149)
| Name |
Fludarabine
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| Synonyms |
FaraA; Fludarabina; Fludarabinum; Fluradosa; Fludarabina [Spanish]; Fludarabine [INN]; Fludarabinum [Latin]; SQ Fludarabine; Fludara, Fludarabine; Fludarabine (INN); Fluradosa (TN); F-Ara-A; (2R,3S,4S,5R)-2-(6-amino-2-fluoro-9H-purin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; (2R,3S,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol; 2-F-ara-A; 2-Fluoro Ara-A; 2-Fluoro-9-beta-D-arabinofuranosyladenine; 9-beta-D-Arabinofuranosyl-2-fluoroadenine; 9-beta-D-arabinofuranosyl-2-fluoro-9H-purin-6-amine; 9H-Purin-6-amine, 9-beta-D-arabinofuranosyl-2-fluoro-(9CI)
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| Structure |
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3D MOL
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| Formula |
C10H12FN5O4
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| InChI |
1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6+,9-/m1/s1
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| InChIKey |
HBUBKKRHXORPQB-FJFJXFQQSA-N
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Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Drug
| In total 1 item(s) under this drug | ||
| Crosstalk ID: M6ACROT00075 | ||
| m6A Regulator | Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) | |
| m6A Target | RNA cytidine acetyltransferase (NAT10) | |
| Epigenetic Regulator | RNA cytidine acetyltransferase (NAT10) | |
| Regulated Target | Acyl-CoA thioesterase 7 (ACOT7) | |
| Crosstalk relationship | m6A → ac4C | |
| Disease | Ovarian cancer | |