General Information of the Drug (ID: M6ADRUG0141)
Name
iFSP1
Synonyms
13-Amino-11-(4-methylphenyl)-1,8-diazatricyclo[7.4.0.0,2,7]trideca-2,4,6,8,10,12-hexaene-10,12-dicarbonitrile, 851-482-1, iFSP1, 150651-39-1, 1-Amino-3-p-tolyl-benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile, 1-amino-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile, MLS000578038, SMR000187223, MFCD01572665, iFSP 1, iFSP-1, iFSP1, Oprea1_094186, cid_699043, CHEMBL1490169, SCHEMBL16941529, BDBM54217, CHEBI:176501, HMS2306H22, AGA65139, EX-A4300, s9663, STK759754, 1-amino-3-(p-tolyl)benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile, AKOS000122129, AC-36527, BS-45796, DA-74421, HY-136057, CS-0119295, EU-0085305, EN300-02854, E73442, AB00097494-01, AG-205/37224011, SR-01000523391, SR-01000523391-1, Z55430237, 1-amino-3-(p-tolyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile, 1-azanyl-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile, 1-AMINO-2-CYANO-3-(4-METHYLPHENYL)PYRIDO[1,2-A][1,3]BENZIMIDAZOL-4-YL CYANIDE, 13-AMINO-11-(4-METHYLPHENYL)-1,8-DIAZATRICYCLO[7.4.0.0(2),]TRIDECA-2,4,6,8,10,12-HEXAENE-10,12-DICARBONITRILE, 13-amino-11-(4-methylphenyl)-1,8-diazatricyclo[7.4.0.0,2,7]trideca-2(7),3,5,8,10,12-hexaene-10,12-dicarbonitrile
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Structure
3D MOL
Formula
C20H13N5
InChI
InChI=1S/C20H13N5/c1-12-6-8-13(9-7-12)18-14(10-21)19(23)25-17-5-3-2-4-16(17)24-20(25)15(18)11-22/h2-9H,23H2,1H3
InChIKey
FNESYDFRCQEEKA-UHFFFAOYSA-N
PubChem CID
699043
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Drug
In total 1 item(s) under this drug
Crosstalk ID: M6ACROT03324
m6A Regulator Methyltransferase-like 3 (METTL3)
m6A Target Ferroptosis suppressor protein 1 (AIFM2)
Epigenetic Regulator Probable JmjC domain-containing histone demethylation protein 2C (JMJD1C)
Regulated Target Histone H3 lysine 9 monomethylation (H3K9me1)
Crosstalk relationship Histone modification → m6A
Disease Brain cancer
References
Ref 1 Mechanism-based inactivation of human cytochrome P4502C8 by drugs in vitro. J Pharmacol Exp Ther. 2004 Dec;311(3):996-1007. doi: 10.1124/jpet.104.071803. Epub 2004 Aug 10.