General Information of the Drug (ID: M6ADRUG0135)
Name
LPS
Synonyms
OD29173, Lipopolysaccharide;KDO-(a,2-4)-KDO-(a,2-6)-lipid A;KDO2-Lipid A;KLA, Di[3-deoxy-D-manno-octulosonyl]-lipid A sodium salt - 0.5mg/ml aqueous solution, OD29173, Lipopolysaccharide;KDO-(a,2-4)-KDO-(a,2-6)-lipid A;KDO2-Lipid A;KLA, Di[3-deoxy-D-manno-octulosonyl]-lipid A sodium salt - 0.5mg/ml aqueous solution
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Structure
3D MOL
Formula
C110H198N2Na4O39P2
InChI
InChI=1S/C110H202N2O39P2.4Na/c1-7-13-19-25-31-37-38-44-50-56-62-68-92(123)142-82(66-60-54-48-42-35-29-23-17-11-5)72-94(125)146-104-96(112-90(121)71-81(65-59-53-47-41-34-28-22-16-10-4)141-91(122)67-61-55-49-43-36-30-24-18-12-6)105(144-88(102(104)150-152(133,134)135)78-140-109(107(129)130)74-86(98(127)101(148-109)85(119)76-114)147-110(108(131)132)73-83(117)97(126)100(149-110)84(118)75-113)139-77-87-99(128)103(145-93(124)70-80(116)64-58-52-46-40-33-27-21-15-9-3)95(106(143-87)151-153(136,137)138)111-89(120)69-79(115)63-57-51-45-39-32-26-20-14-8-2;;;;/h79-88,95-106,113-119,126-128H,7-78H2,1-6H3,(H,111,120)(H,112,121)(H,129,130)(H,131,132)(H2,133,134,135)(H2,136,137,138);;;;/q;4*+1/p-4/t79-,80-,81-,82-,83,84-,85-,86,87,88,95,96,97,98,99,100,101,102,103,104,105,106,109,110;;;;/m1..../s1
InChIKey
LCJLFVJYTHXFIW-WSMSXMIBSA-J
PubChem CID
172642637
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Drug
In total 1 item(s) under this drug
Crosstalk ID: M6ACROT05725
m6A Regulator Methyltransferase-like 14 (METTL14)
m6A Target TNF and HNRNPL related immunoregulatory long non-coding RNA (THRIL)
Epigenetic Regulator TNF and HNRNPL related immunoregulatory long non-coding RNA (THRIL)
Crosstalk relationship m6A → ncRNA
Disease Injury of other or unspecified intrathoracic organs
References
Ref 1 Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med. 2001 Jan;7(1):108-13. doi: 10.1038/83241.
Ref 2 Antitumor efficacy of a thrombospondin 1 mimetic CovX-body. Transl Oncol. 2011 Aug;4(4):249-57. doi: 10.1593/tlo.11136. Epub 2011 Aug 1.