m6A-centered Disease Response Information

General Information of the Disease (ID: M6ADIS0257)
Name
Diabetic
ICD
ICD-11: 5A14
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Disease
In total 1 item(s) under this disease
Crosstalk ID: M6ACROT02046
 Crosstalk Info 
m6A Regulator Wilms tumor 1-associating protein (WTAP)
 Regulator Info 
m6A Target DNA (cytosine-5)-methyltransferase 1 (DNMT1)
 Target Gene 
Epigenetic Regulator DNA (cytosine-5)-methyltransferase 1 (DNMT1)
Crosstalk relationship m6A → DNA modification
References
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Ref 3 Prevent Oral Cancer With Mouthwash. Introgen Therapeutics.
Ref 4 Discovery and preclinical evaluation of anti-miR-17 oligonucleotide RGLS4326 for the treatment of polycystic kidney disease. Nat Commun. 2019 Sep 12;10(1):4148. doi: 10.1038/s41467-019-11918-y.
Ref 5 Metabolism and Disposition of Pan-Genotypic Inhibitor of Hepatitis C Virus NS5A Ombitasvir in Humans. Drug Metab Dispos. 2016 Aug;44(8):1148-57. doi: 10.1124/dmd.115.067496. Epub 2016 May 13.
Ref 6 NPS-1034, a novel MET inhibitor, inhibits the activated MET receptor and its constitutively active mutants. Invest New Drugs. 2014 Jun;32(3):389-99. doi: 10.1007/s10637-013-0039-4. Epub 2013 Oct 31.
Ref 7 In?vitro metabolism of fenofibric acid by carbonyl reducing enzymes. Chem Biol Interact. 2016 Oct 25;258:153-8. doi: 10.1016/j.cbi.2016.09.001. Epub 2016 Sep 4.