m6A-centered Disease Response Information

General Information of the Disease (ID: M6ADIS0223)
Name
Maxillofacial bone defect is a critical obstacle for maxillofacial tumors and periodontal diseases.
ICD
ICD-11: NA02
Full List of Crosstalk(s) between m6A Modification and Epigenetic Regulation Related to This Disease
In total 1 item(s) under this disease
Crosstalk ID: M6ACROT05061
 Crosstalk Info 
m6A Regulator YTH domain-containing family protein 2 (YTHDF2)
 Regulator Info 
m6A Target Fibulin-1 (FBLN1)
 Target Gene 
Epigenetic Regulator hsa-miR-615-3p
Regulated Target YTH domain-containing family protein 2 (YTHDF2)
Crosstalk relationship ncRNA → m6A
References
Ref 1 Synthesis and biological evaluation of substrate-based inhibitors of 6-phosphogluconate dehydrogenase as potential drugs against African trypanosomiasis. Bioorg Med Chem. 2003 Jul 17;11(14):3205-14. doi: 10.1016/s0968-0896(03)00191-3.
Ref 2 The cyclolignan picropodophyllin attenuates intimal hyperplasia after rat carotid balloon injury by blocking insulin-like growth factor-1 receptor signaling. J Vasc Surg. 2007 Jul;46(1):108-15. doi: 10.1016/j.jvs.2007.02.066.