m6A-centered Crosstalk Information
Mechanism of Crosstalk between m6A Modification and Epigenetic Regulation
| Crosstalk ID |
M6ACROT05769
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[1] | |||
m6A modification
Circ_PRKAR1B
Circ_PRKAR1B
METTL3
Methylation
: m6A sites
Direct
Enhancement
Non-coding RNA
circPRKAR1B
SPTBN1
lncRNA miRNA circRNA
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| m6A Modification: | |||||
|---|---|---|---|---|---|
| m6A Regulator | Methyltransferase-like 3 (METTL3) | WRITER | |||
| m6A Target | Circ_PRKAR1B | ||||
| Epigenetic Regulation that have Cross-talk with This m6A Modification: | |||||
| Epigenetic Regulation Type | Non-coding RNA (ncRNA) | ||||
| Epigenetic Regulator | Circ_PRKAR1B | circRNA | View Details | ||
| Regulated Target | Spectrin beta, non-erythrocytic 1 (SPTBN1) | View Details | |||
| Crosstalk Relationship | m6A → ncRNA | Enhancement | |||
| Crosstalk Mechanism | m6A regulators directly modulate the functionality of ncRNAs through specific targeting ncRNA | ||||
| Crosstalk Summary | METTL3-mediated m6 A modification of Circ_PRKAR1B promotes Crohn's colitis by by interacting with Spectrin beta, non-erythrocytic 1 (SPTBN1). | ||||
| Responsed Disease | Crohn disease | ICD-11: DD70.3 | |||
| Pathway Response | Autophagy | hsa04140 | |||
| Cell Process | Pyroptosis | ||||
| Cell autophagy | |||||
In-vitro Model |
NCM460 | Normal | Homo sapiens | CVCL_0460 | |
| HCoEpiC (Healthy colon epithelial HCoEpiC cells) | |||||
| In-vivo Model | Twelve-week-old wild-type (WT) and IL-10-KO mice were allocated randomly to four groups (n = 5 per group): (1) the WT group; (2) the IL-10 KO + si-control group (administrated saline as a placebo via enema once); (3) the IL-10 KO + si-circPRKAR1B group (administrated 200 μL of 1e11 vg adeno-associated virus (AAV) vector carrying si-circPRKAR1B via enema once); and (4) the IL-10 KO + si-METTL3 group (administrated 200 μL of 1e11 vg AAV vector carrying si-METTL3 via enema once). | ||||
Full List of Potential Compound(s) Related to This m6A-centered Crosstalk
| Spectrin beta, non-erythrocytic 1 (SPTBN1) | 1 Compound(s) Regulating the Target | Click to Show/Hide the Full List | ||
| ABT-413 | Phase 1 | [2] | ||
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| DD70: Crohn disease | 265 Compound(s) Regulating the Disease | Click to Show/Hide the Full List | ||
| Natalizumab | Approved | [3] | ||
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| Clofazimine | Approved | [4] | ||
| Synonyms |
2030-63-9; Lamprene; Lampren; Chlofazimine; Clofazimina; Clofaziminum; Clofaziminum [INN-Latin]; B 663 (Pharmaceutical); Clofazimina [INN-Spanish]; B-663; NSC-141046; G 30320; UNII-D959AE5USF; B 663 (VAN); C27H22Cl2N4; 3-(p-Chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin; B 663; 3-(p-Chloroanilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)phenazine; 3-(p-Chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)-phenazine; EINECS 217-980-2; CFZ; SMP2_000339; B 663, pharmaceutical; G-30320; Lamprene (TN); Liposome-encapsulated clofazimine; Clofazimine [USAN:INN:BAN]; G-30,320; Clofazimine (JAN/USP/INN); N,5-bis(4-chlorophenyl)-3-propan-2-yliminophenazin-2-amine; N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(isopropylimino)phenazin-2-amine; N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-(1-methylethyl)imino)-2-phenazinamine; N,5-Bis(4-chlorophenyl)-3,5-dihydro-3-[(1-methylethyl)imino]-2-phenazinamine; N,5-bis(4-chlorophenyl)-3-(propan-2-ylimino)-3,5-dihydrophenazin-2-amine; (3Z)-N,5-bis(4-chlorophenyl)-3-[(1-methylethyl)imino]-3,5-dihydrophenazin-2-amine; 3-(p-Chloranilino)-10-(p-chlorophenyl)-2,10-dihydro-2-(isopropylimino)phenazine; 3-(p-Chloranilino)-10-(p-chlorphenyl)-2,10-dihydro-2-(isopropylimino)-phenazin [German]; Riminophenazine
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| MLN0002 | Approved | [5] | ||
| Synonyms |
Vedolizumab
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| Vedolizmab | Approved | [6] | ||
| Synonyms |
4168-17-6
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| Metronidazole | Phase 3 | [7] | ||
| Synonyms |
APMN; Acromona; Anagiardil; Arilin; Atrivyl; Bexon; CONT; Clont; Danizol; Deflamon; Efloran; Elyzol; Entizol; Eumin; Flagemona; Flagesol; Flagil; Flagyl; Flegyl; Florazole; Fossyol; Giatricol; Gineflavir; Giniflavir; Klion; Klont; Meronidal; Methronidazole; Metric; MetroCream; MetroGel; MetroLotion; Metrodzhil; Metrogyl; Metrolag; Metrolyl; Metromidol; Metronidaz; Metronidazol; Metronidazolo; Metronidazolum; Metrotop; Metrozine; Metryl; Mexibol; Monagyl; Monasin; NIDA; Nalox; Nidagel; Noritate; Novonidazol; Orvagil; Protostat; Rathimed; Rosased; Sanatrichom; Satric; Takimetol; Trichazol; Trichex; Trichocide; Trichomol; Trichopal; Trichopol; Tricocet; Tricom; Trikacide; Trikamon; Trikojol; Trikozol; Trimeks; Trivazol; Vagilen; Vagimid; Vandazole; Vertisal; Wagitran; Zadstat; Zidoval; Flagyl Er; Ginefla vir; METRONIDAZOLE USP; Metro Cream; Metro Gel; Metronidazole Monohydrochloride; Metronidazole Phosphoester; Metronidazole in Plastic Container; Metronidazolo [DCIT]; Tricho cordes; Trichomonacid pharmachim; Tricowas B; Bayer 5360; Flagyl 375; M0924; Metric 21; RP 8823; SC 10295; Anabact (TN); Apo-Metronidazole; Deflamon-wirkstoff; Flagyl (TN); IDR-90105; METRO I.V; MetroGel (TN); MetroGel-Vaginal; Metronidazol [INN-Spanish]; Metronidazolum [INN-Latin]; Mexibol (silanes); Neo-Tric; Noritate (TN); RP-8823; Rozex (TN); Tricho-gynaedron; ZERO/004064; CB-01-14 MMX; FLAGYL I.V. RTU IN PLASTIC CONTAINER; Flagyl I.V.; Flagyl I.V. RTU; Metro I.V.; Metro I.V. In Plastic Container; Metrogel-vaginal (TN); Metronidazole (JP15/USP/INN); Metronidazole [USAN:INN:BAN:JAN]; Methyl-5-nitroimidazole-1-ethanol; 1-Hydroxyethyl-2-methyl-5-nitroimidazole; 2-(2-methyl-5-nitroimidazol-1-yl)ethanol; 2-Methyl-5-nitro-1-imidazoleethanol; 2-Methyl-5-nitroimidazole-1-ethanol; MNZ
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| Mercaptopurine | Phase 4 | [8] | ||
| Synonyms |
6-mercaptopurine; Ismipur; Leukerin; Leupurin; Mercaleukim; Mercaleukin; Mercaptopurin; Mercaptopurina; Mercaptopurinum; Mercapurin; Merkaptopuryna; Mern; Purimethol; Purinethiol; Purinethol; Thiopurine; Leupu rin; Mercaptopurin [German]; Mercaptopurina Wellcome; Mercaptopurine anhydrous; Merkaptopuryna [Polish]; Puri Nethol; BW 57 323H; Glaxo Wellcome Brand of 6 Mercaptopurine; GlaxoSmithKline Brand of 6 Mercaptopurine; M0063; NCIMech_000025; PM6; Wellcome Brand of 6 Mercaptopurine; Glaxo Wellcome Brand of 6-Mercaptopurine; GlaxoSmithKline Brand of 6-Mercaptopurine; Mercaptopurina [INN-Spanish]; Mercaptopurine (INN); Mercaptopurine (VAN); Mercaptopurine (anhydrous); Mercaptopurinum [INN-Latin]; Puri-Nethol; Purineantimetabolite: inhibits nucleic acid replication; Purinethol (TN); U-4748; Wellcome Brand of 6-Mercaptopurine; AG-670/31547064; Purine-6-thiol; Leukerin, 99%-Carc; Purine-6(1H)-thione; Purinethol, 6-mercaptopurine, 6-MP, Mercaptopurine; 6 MP; 6 Mercaptopurine Monohydrate; 6 Thiohypoxanthine; 6 Thiopurine; 6-MERCAPTOPURINE MONOHYDRATE; 6-MP; 6-Mercaptopurin; 6-Merkaptopurin; 6-Merkaptopurin [Czech]; 6-Purinethiol; 6-Thiohypoxanthine; 6-Thiopurine; 6-Thioxopurine; Mercaptopurine (Purine analog)
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| Upadacitinib | Approved | [9] | ||
| Synonyms |
ABT-494
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| Plecanatide | Phase 3 | [10] | ||
| Synonyms |
Trulance
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| Ozanimod | Phase 3 | [9] | ||
| Synonyms |
1306760-87-1; Ozanimod (RPC1063); UNII-Z80293URPV; Z80293URPV; (S)-5-(3-(1-((2-hydroxyethyl)amino)-2,3-dihydro-1H-inden-4-yl)-1,2,4-oxadiazol-5-yl)-2-isopropoxybenzonitrile; Ozanimod [USAN:INN]; Ozanimod (USAN/INN); SCHEMBL2195490; GTPL8709; CHEMBL3707247; 5-[3-[(1S)-1-(2-hydroxyethylamino)-2,3-dihydro-1H-inden-4-yl]-1,2,4-oxadiazol-5-yl]-2-propan-2-yloxybenzonitrile; EX-A1316; s7952; ZINC116109867; AKOS026674086; DB12612; CS-5070; HY-12288; AC-29883; Benzonitrile, 5-(3-((1
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| Ritlecitinib | Approved | [9] | ||
| Synonyms |
CBRJPFGIXUFMTM-WDEREUQCSA-N; 1792180-81-4; UNII-2OYE00PC25; 2OYE00PC25; PF06651600; 1-((2S,5R)-5-((7H-Pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one; GTPL9559; SCHEMBL16764638; BCP24778; EX-A2613; ZINC526061581; example 5 [WO2015083028]; ACN-040697; compound 11 [PMID: 28139931]; HY-100754; CS-0020243; 1-[(2S,5R)-2-Methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)-1-piperidinyl]-2-propen-1-one malonate; 1-[(2S,5R)-2-methyl-5-(7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)piperidin-1-yl]prop-2-en-1-one
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| Citric acid, magnesium oxide, sodium picosulfate | Approved | [11] | ||
| Synonyms |
Prepopik (TN)
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| PB006 | Phase 3 | [12] | ||
| Synonyms |
Natalizumab Biosimilar
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| Alofisel | Phase 3 | [13] | ||
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| Brazikumab | Phase 3 | [14] | ||
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| SHR0302 | Phase 3 | [15] | ||
| Synonyms |
(3AR,5S,6AS)-N-(3-METHOXY-1,2,4-THIADIAZOL-5-YL)-5-(METHYL (7H-PYRROLO(2,3- D)PYRIMIDIN-4-YL)AMINO) HEXAHYDROCYCLOPENTA(C)PYRROLE-2(1H)-CARBOXAMIDE; (3aR,5s,6aS)-N-(3-methoxy-1,2,4-thiadiazol-5-yl)-5-(methyl (7H-pyrrolo(2,3-d)pyrimidin-4-yl)amino) hexahydrocyclopenta(c)pyrrole-2(1H)-carboxamide; (3aR,6aS)-N-(3-methoxy-1,2,4-thiadiazol-5-yl)-5-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxamide; (3aS,6aR)-N-(3-methoxy-1,2,4-thiadiazol-5-yl)-5-[methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]-3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrole-2-carboxamide; 1445987-21-2; AC-36766; AKOS040759719; CHEMBL5095398; CS-0062969; CYCLOPENTA(C)PYRROLE-2(1H)-CARBOXAMIDE, HEXAHYDRO-N-(3-METHOXY-1,2,4- THIADIAZOL-5-YL)-5-(METHYL-7H-PYRROLO(2,3-D)PYRIMIDIN-4-YLAMINO)-, (3A.ALPHA.,5.ALPHA.,6A.ALPHA.)-; Cyclopenta(c)pyrrole-2(1H)-carboxamide, hexahydro-N-(3-methoxy-1,2,4-thiadiazol-5-yl)-5-(methyl-7H-pyrrolo(2,3-d)pyrimidin-4-ylamino)-, (3aalpha,5alpha,6aalpha)-; EX-A5101; example 34 [WO2013091539A1]; F82248; GTPL11878; HY-112724; Ivarmacitinib; IVARMACITINIB [INN]; Ivarmacitinib [USAN]; K6K4B9Z5TV; MS-27180; NCGC00687790-01; rel-(3aR,5s,6aS)-N-(3-Methoxy-1,2,4-thiadiazol-5-yl)-5-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxamide; SCHEMBL15077696; SCHEMBL15077710; SCHEMBL16191633; SHR0302; SHR-0302; SHR0302 base; SHR0302 FREE BASE; SHR-0302 FREE BASE; UNII-K6K4B9Z5TV; US9527851, 34; US9527851, 74; WHO 11823
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| Remestemcel-L | Phase 3 | [16] | ||
| Synonyms |
MSC-100-IV
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| Entyvio | Phase 3 | [9] | ||
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| GS-5745 | Phase 3 | [9] | ||
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| RHB-104 | Phase 3 | [9] | ||
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| Etrolizumab | Phase 3 | [9] | ||
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| Alicaforsen | Phase 3 | [17] | ||
| Synonyms |
Alicaforsen [INN]; ISIS 2302; ISIS-2302; Intercellular adhesion molecule-1 antisense oligodeoxynucleotide; DNA, d((R)-P-thio)(G-C-C-A-A-G-C-T-G-G-C-A-T-C-C-G-T-C-A); Deoxyribonucleic acid, d((R)-P-thio)(G-C-C-C-A-A-G-C-T-G-G-C-A-T-C-C-G-T-C-A)
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| AJM-300 | Phase 3 | [18] | ||
| Synonyms |
Alpha-4 integrin antagonist (inflammatory bowel disease), Ajinomoto
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| Vercirnon | Phase 3 | [19] | ||
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| ABT-874 | Discontinued in Phase 2 | [20] | ||
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| Sivelestat | Application submitted | [9] | ||
| Synonyms |
127373-66-4; UNII-DWI62G0P59; 2-[[2-[[4-(2,2-dimethylpropanoyloxy)phenyl]sulfonylamino]benzoyl]amino]acetic acid; Elastase Inhibitor IV; C20H22N2O7S; N-(2-(4-(2,2-Dimethylpropionyloxy)phenylsulfonylamino)benzoyl)aminoacetic acid; Sivelestat (ONO-5046); LY544349; CHEMBL76688; LY 544349; DWI62G0P59; Glycine, N-(2-(((4-(2,2-dimethyl-1-oxopropoxy)phenyl)sulfonyl)amino)benzoyl)-; N-(o-(p-Pivaloyloxybenzene)sulfonylaminobenzoyl)glycine
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| SB2 | Application submitted | [9] | ||
| Synonyms |
Antimony; 7440-36-0; Stibium metallicum; Antimony, metallic; UNII-9IT35J3UV3; Antymonowodor [Polish]; UNII-0VKZ97K3UB; 0VKZ97K3UB; Antimonwasserstoffes [German]; HSDB 785; 9IT35J3UV3; UN2676; Antymon; Antimonio; Antimoine; Antimony powder; MFCD00011211; Antimonyl citrate; Antimony, ion(Sb2+); Sb2+; stibanylidyne; Antimonide; Antymonowodor; Antimon; antimony atom; Antimony, citric acid complexes; antimony(0); Antimonwasserstoffes; EINECS 270-130-2; ANTIMONOUS HYDRIDE; ACMC-1BKT5; 51Sb; EC 231-146-5; AC1NS5Q0; Sb(0); ANT
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| Rifaximin DR | Phase 3 | [9] | ||
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| BI 655066 | Phase 2 | [9] | ||
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| GED-0301 | Phase 3 | [9] | ||
| Synonyms |
SMAD-7 inhibitor (oligonucleotide, Crohn's disease), Giuliani
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| MSC-100-IV | Phase 3 | [9] | ||
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| Prochymal | Phase 3 | [21] | ||
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| SHP647 | Phase 3 | [9] | ||
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| MORF-057 | Phase 2 | [22] | ||
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| BI 706321 | Phase 2 | [23] | ||
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| TEV-48574 | Phase 2 | [24] | ||
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| EB8018 | Phase 2 | [25] | ||
| Synonyms |
Sibofimloc; 1616113-45-1; Antibiotic-202; VRT-1353385; UNII-00OF00QZC4; 1-[2,7-Bis[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]ethynyl]spiro[fluorene-9,4'-piperidine]-1'-yl]ethanone; 1-[2,7-bis({2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]ethynyl})spiro[fluorene-9,4'-piperidine]-1'-yl]ethan-1-one; 1-[2,7-bis[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]ethynyl]spiro[fluorene-9,4'-piperidine]-1'-yl]ethanone; Sibofimloc [INN]; Sibofimloc [USAN]; Sibofimloc (USAN/INN); CHEMBL4594305; SCHEMBL15836795; EX-A750; Antibiotic-202;VRT-1353385; MFCD28144726; WHO 10950; ZINC209678340; ACN-052475; CS-5487; DA-43714; HY-12820; B5896; D11825; J-690221; 1-(2,7-Bis(2,6-anhydro-7,8-dideoxy-D-glycero-D-manno-oct-7-ynitol-8-yl)spiro(fluorene-9,4'-piperidin)-1'-yl)ethan-1-one; 1-[2,7-bis[2-[(2R,3S,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]ethynyl]spiro[fluorene-9,4a?piperidine]-1a?yl]ethanone; 8,8'-(1'-Acetylspiro(9H-fluorene-9,4'-piperidine)-2,7-diyl)bis(2,6-anhydro-7,8-dideoxy-D-glycero-D-manno-oct-7-ynitol); D-Glycero-D-manno-oct-7-ynitol, 8,8'-(1'-acetylspiro(9H-fluorene-9,4'-piperidine)-2,7-diyl)bis(2,6-anhydro-7,8-dideoxy-
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| PRA023 | Phase 2 | [26] | ||
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| ABBV-154 | Phase 2 | [27] | ||
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| Alequel | Phase 2 | [9] | ||
| Synonyms |
Antigens (colitis), Enzo; Antigen-specific immune regulation therapy (Crohn`s), Enzo
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| YSIL6 | Phase 2 | [28] | ||
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| CC-1088 | Phase 2 | [29] | ||
| Synonyms |
CDC801; CHEMBL88153; SCHEMBL185853; CDC-801; DDYUBCCTNHWSQM-UHFFFAOYSA-N; BDBM50216298; HY-U00179; CS-7247; 192819-27-5
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| GLPG-0634 | Phase 2 | [9] | ||
| Synonyms |
Small molecule, JAK1/JAK2 inhibitor (rheumatoid arthritis), Galapagos/GSK
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| Anti-IP10 | Phase 2 | [30] | ||
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| APD371 | Phase 2 | [31] | ||
| Synonyms |
Olorinab; UNII-581F7DFA9B; 581F7DFA9B; Olorinab [USAN]; SCHEMBL11995430; 1268881-20-4; (4aS,5aS)-N-((2S)-1-hydroxy-3,3-dimethylbutan-2-yl)-1-(4-oxidopyrazin-2-yl)-4,4a,5,5a-tetrahydro-1H-cyclopropa(4,5)cyclopenta(1,2-c)pyrazole-3-carboxamide; 1H-Cyclopropa(4,5)cyclopenta(1,2-c)pyrazole-3-carboxamide, 4,4a,5,5a-tetrahydro-N-((1S)-1-(hydroxymethyl)-2,2-dimethylpropyl)-1-(4-oxido-2-pyrazinyl)-, (4aS,5aS)-; (1aS,5aS)-2-(4-Oxy-pyrazin-2-yl)-1a,2,5,5a-tetrahydro-1H-2,3-diaza-cyclopropa(a)pentalene-4-carboxylic aci
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| OPS-2071 | Phase 2 | [32] | ||
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| MEDI2070 | Phase 2 | [33] | ||
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| EGS-21 | Phase 2 | [34] | ||
| Synonyms |
Glucocerebroside, Enzo; Glucosylceramide, Enzo Biochem
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| GSK2330811 | Phase 2 | [35] | ||
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| STA-5326 | Phase 2 | [36] | ||
| Synonyms |
Apilimod; STA 5326; STA5326; N-[(3-methylphenyl)methylideneamino]-6-morpholin-4-yl-2-(2-pyridin-2-ylethoxy)pyrimidin-4-amine
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| MDX-1100 | Phase 2 | [37] | ||
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| PF-04236921 | Phase 2 | [9] | ||
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| NN8555 | Phase 2 | [9] | ||
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| AMG-181 | Phase 2 | [38] | ||
| Synonyms |
Inflammatory bowel disease therapeutics, Amgen
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| SGX203 | Phase 2 | [9] | ||
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| Clazakizumab | Phase 2 | [39] | ||
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| MT-1303 | Phase 2 | [9] | ||
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| EcoActive | Phase 1/2 | [40] | ||
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| AZD7798 | Phase 1 | [41] | ||
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| OSSM-001 | Phase 1 | [42] | ||
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| ONS-3010 | Phase 1 | [9] | ||
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| ATR-107 | Phase 1 | [43] | ||
| Synonyms |
PF-05230900
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| ChronsVax | Phase 1 | [9] | ||
| Synonyms |
Crohn's disease vaccine; IR-777
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| C326 | Phase 1 | [44] | ||
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| AMG-139 | Phase 1 | [45] | ||
| Synonyms |
Anti-inflammatory agent (psoriasis, IBD), Amgen
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| TAK-828 | Phase 1 | [9] | ||
| Synonyms |
ICMFYVOUDGRBLG-NJMNTPMDSA-N; TAK828F; GTPL9867; TAK-828F; SCHEMBL17390967; SCHEMBL17390969; SCHEMBL17391123; ICMFYVOUDGRBLG-VFHHBZAHSA-N; ICMFYVOUDGRBLG-XVNUGVHUSA-N; compound 10 [PMID: 29510038]; E3V; {cis-3-[(5R)-5-[(7-fluoro-1,1-dimethyl-1H-inden-5-yl)carbamoyl]-2-methoxy-7,8-dihydro-1,6-naphthyridine-6(5H)-carbonyl]cyclobutyl}acetic acid; (cis-3-(((5R)-5-((7-fluoro-1,1-dimethyl-2,3-dihydro-1H-inden-5-yl)carbamoyl)-2-methoxy-7,8-dihydro-1,6-naphthyridin-6 (5H)-yl)carbonyl)cyclobutyl)acetic acid; (cis-3-(((5R)-5-((7-fluoro-1,1-dimethyl-2
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|
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| External Link | ||||
| CrohnsVax | Phase 1 | [46] | ||
| External Link | ||||
| ETX201 | Phase 1 | [9] | ||
| External Link | ||||
| VBY-129 | Phase 1 | [9] | ||
| Synonyms |
Cathepsin S inhibitor (oral, psoriasis), Virobay
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|
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| External Link | ||||
| SAR252067 | Phase 1 | [47] | ||
| External Link | ||||
| PF-06480605 | Phase 1 | [48] | ||
| External Link | ||||
| ABBV-323 | Phase 1 | [9] | ||
| External Link | ||||
| CCX-025 | Phase 1 | [49] | ||
| Synonyms |
CCX-807; CCR9 chemokine receptor-targeting therapeutic (gastrointestinal diseases), ChemoCentryx
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|
|||
| External Link | ||||
| Biaryl mannoside derivative 6 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-2f
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|
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| External Link | ||||
| Biaryl mannoside derivative 3 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-2c
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|
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| External Link | ||||
| Alkyl mannoside derivative 2 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-1b
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|
|||
| External Link | ||||
| Mannoside derivative 2 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-101
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|
|||
| External Link | ||||
| Biphenyl mannoside derivative 16 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-51
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|
|||
| External Link | ||||
| PMID26651364-Compound-126b | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-7d | Patented | [50] | ||
| External Link | ||||
| Aryl mannoside derivative 7 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-18
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|
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| External Link | ||||
| Biaryl mannoside derivative 28 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-64
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|
|||
| External Link | ||||
| Mannoside derivative 5 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-104
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|
|||
| External Link | ||||
| C-linked disaccharide biphenyl mannoside derivative 3 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-88
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|
|||
| External Link | ||||
| Mannoside derivative 4 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-103
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|
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| External Link | ||||
| PMID26651364-Compound-50 | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-118 | Patented | [50] | ||
| External Link | ||||
| Aryl mannoside derivative 18 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-80
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|
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| External Link | ||||
| Beta-cyclodextrin conjugate derivative 5 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-133
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|
|||
| External Link | ||||
| PMID26651364-Compound-49 | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-111 | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 20 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-55
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|
|||
| External Link | ||||
| PMID26651364-Compound-5b | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 23 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-68b
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|
|||
| External Link | ||||
| PMID26651364-Compound-107 | Patented | [50] | ||
| External Link | ||||
| Aryl mannoside derivative 9 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-20
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|
|||
| External Link | ||||
| Alkyl mannoside derivative 1 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-1a
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|
|||
| External Link | ||||
| PMID26651364-Compound-6d | Patented | [50] | ||
| External Link | ||||
| C-linked disaccharide biphenyl mannoside derivative 2 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-87
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|
|||
| External Link | ||||
| PMID26651364-Compound-126a | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 7 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-31
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|
|||
| External Link | ||||
| Biphenyl mannoside derivative 28 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-73
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|
|||
| External Link | ||||
| Alkyl mannoside derivative 6 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-Table2R1=n-alkyl04
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|
|||
| External Link | ||||
| Mannoside derivative 9 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-95
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|
|||
| External Link | ||||
| PMID26651364-Compound-113 | Patented | [50] | ||
| External Link | ||||
| Aryl mannoside derivative 20 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-82
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|
|||
| External Link | ||||
| Biphenyl mannoside derivative 29 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-74
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|
|||
| External Link | ||||
| Biphenyl mannoside derivative 1 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-25
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|
|||
| External Link | ||||
| PMID26651364-Compound-124 | Patented | [50] | ||
| External Link | ||||
| Alkyl mannoside derivative 3 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-Table2R1=n-alkyl01
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|
|||
| External Link | ||||
| Aryl mannoside derivative 11 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-22
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|
|||
| External Link | ||||
| Biphenyl mannoside derivative 17 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-52
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|
|||
| External Link | ||||
| Biaryl mannoside derivative 22 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-44
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|
|||
| External Link | ||||
| Biphenyl mannoside derivative 13 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-37
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|
|||
| External Link | ||||
| Mannoside derivative 3 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-102
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|
|||
| External Link | ||||
| Aryl mannoside derivative 10 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-21
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|
|||
| External Link | ||||
| Biaryl mannoside derivative 29 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-65
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|
|||
| External Link | ||||
| Biaryl mannoside derivative 1 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-2a
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|
|||
| External Link | ||||
| Aryl mannoside derivative 16 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-78
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|
|||
| External Link | ||||
| PMID26651364-Compound-47 | Patented | [50] | ||
| External Link | ||||
| Beta-cyclodextrin conjugate derivative 2 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-130
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|
|||
| External Link | ||||
| PMID26651364-Compound-5f | Patented | [50] | ||
| External Link | ||||
| Biaryl mannoside derivative 23 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-59
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|
|||
| External Link | ||||
| Mannoside derivative 13 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-99
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|
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| External Link | ||||
| PMID26651364-Compound-7e | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-9c | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-8d | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-11c | Patented | [50] | ||
| External Link | ||||
| Biaryl mannoside derivative 25 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-61
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|
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| External Link | ||||
| Mannoside derivative 1 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-100
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| External Link | ||||
| PMID26651364-Compound-8c | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-10b | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 8 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-32
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|||
| External Link | ||||
| PMID26651364-Compound-106 | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 11 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-35
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|
|||
| External Link | ||||
| Biphenyl mannoside derivative 19 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-54
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|
|||
| External Link | ||||
| PMID26651364-Compound-10d | Patented | [50] | ||
| External Link | ||||
| Alkyl mannoside derivative 5 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-Table2R1=n-alkyl03
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|
|||
| External Link | ||||
| Beta-cyclodextrin conjugate derivative 1 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-129
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|
|||
| External Link | ||||
| PMID26651364-Compound-122 | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-6c | Patented | [50] | ||
| External Link | ||||
| Aryl mannoside derivative 8 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-19
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|
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| External Link | ||||
| Biphenyl mannoside derivative 27 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-72
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|
|||
| External Link | ||||
| Alkyl mannoside derivative 4 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-Table2R1=n-alkyl02
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|
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| External Link | ||||
| Aryl mannoside derivative 6 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-17
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|
|||
| External Link | ||||
| PMID26651364-Compound-9b | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-46 | Patented | [50] | ||
| External Link | ||||
| Biaryl mannoside derivative 27 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-63
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|
|||
| External Link | ||||
| PMID26651364-Compound-112 | Patented | [50] | ||
| External Link | ||||
| Biaryl mannoside derivative 11 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-3c
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|
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| External Link | ||||
| PMID26651364-Compound-127 | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-4 | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-110 | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-117a | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-9f | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 18 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-53
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|
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| External Link | ||||
| Mannoside derivative 11 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-97
Click to Show/Hide
|
|||
| External Link | ||||
| C-linked disaccharide biphenyl mannoside derivative 1 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-86
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|
|||
| External Link | ||||
| Biaryl mannoside derivative 19 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-41
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|
|||
| External Link | ||||
| Biaryl mannoside derivative 2 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-2b
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|
|||
| External Link | ||||
| Biphenyl mannoside derivative 22 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-68a
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|
|||
| External Link | ||||
| PMID26651364-Compound-115 | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 9 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-33
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| External Link | ||||
| PMID26651364-Compound-10a | Patented | [50] | ||
| External Link | ||||
| Aryl mannoside derivative 2 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-13
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| External Link | ||||
| Aryl mannoside derivative 3 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-14
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|
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| External Link | ||||
| PMID26651364-Compound-120 | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-6a | Patented | [50] | ||
| External Link | ||||
| Biaryl mannoside derivative 13 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-3e
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| External Link | ||||
| Mannoside derivative 6 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-92
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| External Link | ||||
| Biaryl mannoside derivative 30 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-66
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|
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| External Link | ||||
| Biaryl mannoside derivative 14 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-3f
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|
|||
| External Link | ||||
| Biphenyl mannoside derivative 15 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-39
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|
|||
| External Link | ||||
| Alkyl mannoside derivative 11 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-Table2R1=n-aryl02
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|
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| External Link | ||||
| PMID26651364-Compound-5g | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-6b | Patented | [50] | ||
| External Link | ||||
| Alkyl mannoside derivative 10 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-Table2R1=n-aryl01
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| External Link | ||||
| Biaryl mannoside derivative 16 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-3h
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| External Link | ||||
| Aryl mannoside derivative 12 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-23
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|||
| External Link | ||||
| Aryl mannoside derivative 17 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-79
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|
|||
| External Link | ||||
| Alkyl mannoside derivative 7 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-Table2R1=n-alkyl05
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| External Link | ||||
| Mannoside derivative 12 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-98
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| External Link | ||||
| PMID26651364-Compound-117b | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 26 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-71
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| External Link | ||||
| PMID26651364-Compound-7c | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-5c | Patented | [50] | ||
| External Link | ||||
| Beta-cyclodextrin conjugate derivative 4 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-132
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|||
| External Link | ||||
| PMID26651364-Compound-45 | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 21 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-56
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|||
| External Link | ||||
| Biphenyl mannoside derivative 2 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-26
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|
|||
| External Link | ||||
| PMID26651364-Compound-8b | Patented | [50] | ||
| External Link | ||||
| Aryl mannoside derivative 14 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-76
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|
|||
| External Link | ||||
| C-linked disaccharide biphenyl mannoside derivative 5 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-90
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|
|||
| External Link | ||||
| Biaryl mannoside derivative 20 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-42
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|
|||
| External Link | ||||
| PMID26651364-Compound-10c | Patented | [50] | ||
| External Link | ||||
| Aryl mannoside derivative 15 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-77
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|
|||
| External Link | ||||
| PMID26651364-Compound-7b | Patented | [50] | ||
| External Link | ||||
| Biaryl mannoside derivative 4 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-2d
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|
|||
| External Link | ||||
| PMID26651364-Compound-9e | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 4 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-28
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|
|||
| External Link | ||||
| Biphenyl mannoside derivative 24 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-69
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|
|||
| External Link | ||||
| Biaryl mannoside derivative 7 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-2g
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|
|||
| External Link | ||||
| Aryl mannoside derivative 13 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-24
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|
|||
| External Link | ||||
| Mannoside derivative 7 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-93
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|
|||
| External Link | ||||
| PMID26651364-Compound-105 | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-5a | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-8a | Patented | [50] | ||
| External Link | ||||
| Biaryl mannoside derivative 18 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-40
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|
|||
| External Link | ||||
| Aryl mannoside derivative 1 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-12
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|
|||
| External Link | ||||
| PMID26651364-Compound-48 | Patented | [50] | ||
| External Link | ||||
| Mannoside derivative 8 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-94
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|
|||
| External Link | ||||
| Biaryl mannoside derivative 5 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-2e
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|
|||
| External Link | ||||
| Aryl mannoside derivative 23 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-85
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|
|||
| External Link | ||||
| Alkyl mannoside derivative 8 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-Table2R1=n-alkyl06
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|
|||
| External Link | ||||
| PMID26651364-Compound-119 | Patented | [50] | ||
| External Link | ||||
| Biaryl mannoside derivative 17 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-3i
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|
|||
| External Link | ||||
| Aryl mannoside derivative 21 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-83
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|
|||
| External Link | ||||
| Alkyl mannoside derivative 12 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-Table2R1=n-aryl03
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|
|||
| External Link | ||||
| Aryl mannoside derivative 22 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-84
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|
|||
| External Link | ||||
| Alkyl mannoside derivative 9 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-Table2R1=n-alkyl07
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|
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| External Link | ||||
| Biaryl mannoside derivative 12 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-3d
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| Aryl mannoside derivative 5 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-16
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| Biaryl mannoside derivative 26 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-62
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| PMID26651364-Compound-5e | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-6e | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 14 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-38
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| PMID26651364-Compound-11b | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 5 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-29
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| PMID26651364-Compound-123 | Patented | [50] | ||
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| PMID26651364-Compound-9a | Patented | [50] | ||
| External Link | ||||
| Mannoside derivative 10 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-96
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| PMID26651364-Compound-126c | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 30 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-75
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| PMID26651364-Compound-125 | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-128 | Patented | [50] | ||
| External Link | ||||
| C-linked disaccharide biphenyl mannoside derivative 4 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-89
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| Biphenyl mannoside derivative 25 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-70
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| External Link | ||||
| Biphenyl mannoside derivative 3 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-27
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| External Link | ||||
| Biphenyl mannoside derivative 12 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-36
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| External Link | ||||
| PMID26651364-Compound-108 | Patented | [50] | ||
| External Link | ||||
| Aryl mannoside derivative 4 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-15
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| PMID26651364-Compound-121 | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 10 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-34
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| Biaryl mannoside derivative 15 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-3g
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| C-linked disaccharide biphenyl mannoside derivative 6 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-91
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| Aryl mannoside derivative 19 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-81
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| PMID26651364-Compound-9d | Patented | [50] | ||
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| PMID26651364-Compound-7a | Patented | [50] | ||
| External Link | ||||
| Biaryl mannoside derivative 9 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-3a
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| External Link | ||||
| Biaryl mannoside derivative 10 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-3b
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| External Link | ||||
| Biaryl mannoside derivative 31 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-67
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| External Link | ||||
| Biaryl mannoside derivative 21 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-43
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| PMID26651364-Compound-5d | Patented | [50] | ||
| External Link | ||||
| Biphenyl mannoside derivative 6 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-30
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| PMID26651364-Compound-114 | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-109 | Patented | [50] | ||
| External Link | ||||
| Beta-cyclodextrin conjugate derivative 3 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-131
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| External Link | ||||
| Biaryl mannoside derivative 8 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-2h
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| External Link | ||||
| PMID26651364-Compound-116 | Patented | [50] | ||
| External Link | ||||
| PMID26651364-Compound-5 | Patented | [50] | ||
| External Link | ||||
| Biaryl mannoside derivative 24 | Patented | [50] | ||
| Synonyms |
PMID26651364-Compound-60
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| External Link | ||||
| CDP571 | Discontinued in Phase 3 | [51] | ||
| External Link | ||||
| ISIS 104838 | Discontinued in Phase 2 | [52] | ||
| External Link | ||||
| TNFQb therapeutic vaccines | Terminated | [53] | ||
| Synonyms |
TNFQb; CYT-020-TNFQb; TNF-targeted vaccine (inflammation, Immunodrug), Cytos Biotechnology; TNFQb therapeutic vaccines (rheumatoid arthritis/psoriasis/Crohn's disease); TNFQb therapeutic vaccines (rheumatoid arthritis/psoriasis/Crohn's disease), Cytos; Immunodrug vaccines (TNF) (rheumatoid arthritis/psoriasis/Crohn's disease), Cytos
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| Mycophenolic acid | Approved | [6] | ||
| External Link | ||||
| STP-432 | Investigative | [54] | ||
| Synonyms |
Multi-targeted siRNA therapeutic (nanoparticle, Crohns disease), Sirnaomics
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References
: m6A sites