m6A-centered Crosstalk Information

Mechanism of Crosstalk between m6A Modification and Epigenetic Regulation
Crosstalk ID
M6ACROT05677
 [1]
m6A modification NME1 NME1 ALKBH5 Demethylation : m6A sites Direct Enhancement Non-coding RNA RMRP Regulated Target  lncRNA       miRNA   circRNA
m6A Modification:
m6A Regulator RNA demethylase ALKBH5 (ALKBH5) ERASER
 Regulator Info 
m6A Target RMRP
 Targert Gene 
Epigenetic Regulation that have Cross-talk with This m6A Modification:
Epigenetic Regulation Type Non-coding RNA (ncRNA)
Epigenetic Regulator RMRP LncRNA View Details
Crosstalk Relationship m6A  →  ncRNA Enhancement
Crosstalk Mechanism m6A regulators directly modulate the functionality of ncRNAs through specific targeting ncRNA
Crosstalk Summary Hypoxia-induced m6A demethylase ALKBH5 promotes ovarian cancer tumorigenicity by decreasing methylation of the lncRNA RMRP.
Responsed Disease Ovarian cancer ICD-11: 2C73
 Disease Info 
Cell Process Cell growth
Cell migration
In-vitro Model
 A2780 Ovarian endometrioid adenocarcinoma Homo sapiens CVCL_0134
SK-OV-3 Ovarian serous cystadenocarcinoma Homo sapiens CVCL_0532
OVCAR-3 Ovarian serous adenocarcinoma Homo sapiens CVCL_0465
HO-8910 Endocervical adenocarcinoma Homo sapiens CVCL_6868
OVCAR-8 High grade ovarian serous adenocarcinoma Homo sapiens CVCL_1629
In-vivo Model Stable cell clones, at a density of 5000 cells, were subcutaneously injected into the right flank of six-week-old male nude (nu/nu) mice (SLAC, Shanghai, China). These clones were infected with SKOV3-Nc and SKOV3-shALKBH5 in 100 uL of sterilized phosphate-buffered saline. Mice were allowed to recover for six weeks before reinjection. In each group, the tumor weights of six mice were measured and recorded. All mice were euthanized within six weeks post-surgery, following the removal of their tumors. Tumor sizes were measured using Vernier calipers, with the volume calculated as 1/2 length × width^2.
Full List of Potential Compound(s) Related to This m6A-centered Crosstalk
2C73: Ovarian cancer 198 Compound(s) Regulating the Disease Click to Show/Hide the Full List
 Compound Name Atezolizumab Approved [2]
External Link
TTD: D0YM2K
 Compound Name Carboplatin Approved [3]
Synonyms
Azanide; Carbopaltin; Carboplatine; Carboplatino; Carboplatinum; Cbdca; Ercar; Paraplatin; Carboplatine [French]; Carboplatino [Spanish]; Carboplatinum [Latin]; C 2538; JM 8; Carboplatin (USAN); IUPAC: Azane; JM-8; Paraplatin (TN); Paraplatin, Carboplatin; Paraplatin-AQ; Cis-Diammine(cyclobutanedicarboxylato)platinumII; Platinum(+2) Cation; Carboplatin (JAN/USP/INN); Carboplatin [USAN:INN:BAN:JAN]; Cyclobutane-1,1-dicarboxylate; Cyclobutane-1,1-dicarboxylic acid; Diammine-1,1-cyclobutane dicarboxylate platinum II; Cis-Diamine[1,1-cyclobutanedicarboxylato]platinum(II); Cis-Diammine(1,1-cyclobutanedicarboxylato) platinum; Cis-Diammine(1,1-cyclobutanedicarboxylato)platinum; Cis-Diammine[1,1-cyclobutane-dicarboxylato] platinum; Diammine(1,1-cyclobutanedicarboxylato)platinum (II); Platinum, {diammine[1,1-cyclobut; Cis-(1,1-Cyclobutanedicarboxylato)diammineplatinum(II); Cis-Diamine(1,1-cyclobutanedicarboxylato)platinum(II); Cis-Diammine(1,1-cyclobutanedicarboxylato)platinum(II); Platinum(II), (1, 1-cyclobutanedicar; Diammine[cyclobutane-1,1-dicarboxylato(2-)-k2O1,O1]platinum; Diammine(cyclobutane-1,1-dicarboxylato(2-)-O,O')platinum; Platinum, diammine(1,1-cyclobutanedicarboxylato(2-)-O,O')-, (SP-4-2); (SP-4-2)-diammine[cyclobutane-1,1-dicarboxylato(2-)-kappa(2)O,O']platinum; 1,1-Cyclobutanedicarboxylate diammine platinum (II); 1,1-Cyclobutanedicarboxylate diammine platinum(II)
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CID: 426756
TTD: D0X7HM
 Compound Name Lurbinectedin Phase 3 [4]
Synonyms
UNII-2CN60TN6ZS; 497871-47-3; 2CN60TN6ZS; Lurbinectedin [INN]; SCHEMBL16152477; DTXSID30198065; DB12674; CS-6323; HY-16293; J3.652.626B
    Click to Show/Hide
External Link
CID: 57327016
TTD: D0V6OA
DrugBank: DB12674
 Compound Name Mirvetuximab soravtansine Approved [2]
Synonyms
ZOHXWSHGANNQGO-QRVRWUFNSA-N; DB12489
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External Link
CID: 91810695
TTD: D0RP2W
 Compound Name Lenvatinib Approved [5]
Synonyms
E 7080; E-7080, E7080; 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxy-quinoline-6-carboxamide
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External Link
CID: 9823820
TTD: D0R0FO
DrugBank: DB09078
 Compound Name Catumaxomab Phase 2 [6]
External Link
TTD: D0O5ER
 Compound Name Avelumab Approved [2]
External Link
TTD: D0K7SX
 Compound Name Olaparib Approved [2]
Synonyms
AZD 2281; AZD2281; AZD-2281; Acylpiperazine analogue, 47; KU-0059436; KU-59436; Olaparib, KU-0059436, AZD2281,KU0059436, AZD2281; 4-[(3-{[4-Cyclopropylcarbonyl)piperazin-4-yl]carbonyl}-4-fluorophenyl)methyl]phtalazin-1(2H)-one; 4-[3-(4-Cyclopropanecarbonyl-piperazine-1-carbonyl)-4-fluoro-benzyl]-2H-phthalazin-1-one
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External Link
CID: 23725625
TTD: D0J9HW
DrugBank: DB09074
 Compound Name Cabozantinib Approved [7]
Synonyms
Cabometyx; Cometriq
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External Link
CID: 25102847
TTD: D0IQ6P
DrugBank: DB08875
 Compound Name Taxol Approved [8]
Synonyms
C47H51NO14; weekly paclitaxel; Micellar Paclitaxel; Paclitaxel [USAN:INN:BAN]; SCHEMBL15000506; Benzenepropanoic acid, beta-(benzoylamino)-alpha-hydroxy-, 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester, (2aR-(2aalpha,4beta,4abeta,6beta,9alpha(alphaR*,betaS*),11alpha,12alpha,12aalpha,12balpha))-
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CID: 36314
TTD: D0C4RB
DrugBank: DB01229
 Compound Name Tisotumab vedotin Phase 2 [9]
External Link
TTD: D0A4GQ
 Compound Name KU-0058948 Approved [10]
Synonyms
CHEMBL380648; 4-[3-(1,4-diazepan-1-ylcarbonyl)-4-fluorobenzyl]phthalazin-1(2H)-one; 4-(3-(1,4-diazepane-1-carbonyl)-4-fluorobenzyl)phthalazin-1(2H)-one; Homopiperazine analogue, 14; SCHEMBL864319; BDBM27533; HGEPGGJUGUMFHT-UHFFFAOYSA-N; ZINC3821234; DB08058; NCGC00386677-01; KU-58948; FT-0670691; TL80090044; 4-[3-([1,4]diazepane-1-carbonyl)-4 -fluorobenzyl]-2H-phthalazin-1-one; 4-[3-([1,4]diazepane-1-carbonyl)-4-fluorobenzyl]-2H-phthalazin-1-one
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CID: 11291932
TTD: D09LSX
DrugBank: DB08058
 Compound Name MVax Approved [11]
Synonyms
MVax (TN)
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TTD: D09JNP
 Compound Name Intedanib Phase 2 [12]
Synonyms
Nintedanib; Vargatef; 656247-17-5; BIBF-1120; BIBF 1120; 928326-83-4; BIBF1120; Nintedanib (BIBF 1120); OFEV; UNII-G6HRD2P839; (Z)-methyl 3-((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenylamino)(phenyl)methylene)-2-oxoindoline-6-carboxylate; G6HRD2P839; CHEBI:85164; 1160294-26-7; Methyl (3z)-3-{[(4-{methyl[(4-Methylpiperazin-1-Yl)acetyl]amino}phenyl)amino](Phenyl)methylidene}-2-Oxo-2,3-Dihydro-1h-Indole-6-Carboxylate
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CID: 135423438
TTD: D09HNV
DrugBank: DB09079
 Compound Name Fluzone QIV Approved [11]
Synonyms
Seasonal influenza vaccine (quadrivalent)
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TTD: D09FHM
 Compound Name Pembrolizumab Approved [2]
External Link
TTD: D08ANZ
 Compound Name Plicamycin Approved [13]
Synonyms
A-2371; NSC24559; PA-144; MTM A; AC1O3EQZ; CHEMBL413720; SCHEMBL14066059; NSC-24559; AKOS030213136; EC-7071; CCG-208236; NCGC00160390-01; NCI60_004287; AB01273958-01
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CID: 163659
TTD: D06EPF
DrugBank: DB06810
 Compound Name Bevacizumab Approved [2]
Synonyms
Bevacizumab (ophthalmic slow-release tissue tablet)
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External Link
TTD: D04KBL
 Compound Name Trabectedin Approved [2]
Synonyms
Ecteinascidin; Ecteinascidin-743; Et-743; Yondelis (TN)
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CID: 108150
TTD: D03RTK
DrugBank: DB05109
 Compound Name Topotecan Approved [14]
Synonyms
Hycamptamine; Hycamptin; Hycamtamine; Topotecane; Topotecanum; Topotecan lactone; SKF 104864; SKF-S 104864; TOPOTECAN, HYCAMTIN; Topotecan (BAN); Topotecan [INN:BAN]; Topotecane [INN-French]; Topotecanum [INN-Latin]; Topotecan Monohydrochloride, (S)-Isomer; (4S)-10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; (S)-10-((Dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]-quinoline-3,14(4H,12H)-dione; (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 9-Dimethylaminomethyl-10-hydroxycamptothecin
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CID: 60700
TTD: D02PMO
DrugBank: DB01030
 Compound Name Altretamine Approved [15]
Synonyms
Altretamina; Altretaminum; HEXAMETHYLMELAMINE; HMM; HTM; HXM; Hemel; Hexalen; Hexastat; Hexinawas; Altretamine Bellon Brand; Altretamine Chiesi Brand; Altretamine Wassermann Brand; Bellon Brand of Altretamine; Chiesi Brand of Altretamine; MGI Pharma Brand of Altretamine; Rhone Poulenc Rorer Brand of Altretamine; Wassermann Brand of Altretamine; A 8723; ENT 50852; NC 195; Altretamina [INN-Spanish]; Altretaminum [INN-Latin]; Hexalen (TN); Hexalen, Altretamine; KB-913; Rhone-Poulenc Rorer Brand of Altretamine; Altretamine (USP/INN); Altretamine [USAN:INN:BAN]; No-s-triazine; N,N,N',N',N'',N''-hexamethyl-1,3,5-triazine-2,4,6-triamine; N~2~,N~2~,N~4~,N~4~,N~6~,N~6~-Hexamethyl-1,3,5-triazine-2,4,6-triamine; 2,4, 6-Tris(dimethylamino)-1,3,5-triazine; 2,4,6-Tris(dimethylami; 2,4,6-Tris(dimethylamino)-1,3,5-triazine; 2,4,6-Tris(dimethylamino-s-triazine; 2-N,2-N,4-N,4-N,6-N,6-N-hexamethyl-1,3,5-triazine-2,4,6-triamine
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CID: 2123
TTD: D02LPF
DrugBank: DB00488
 Compound Name Rucaparib Approved [16]
Synonyms
283173-50-2; Rubraca; AG-14447; UNII-8237F3U7EH; 8237F3U7EH; AK317822; 8-Fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-6H-pyrrolo[4,3,2-ef][2]benzazepin-6-one; 8-FLUORO-2-(4-((METHYLAMINO)METHYL)PHENYL)-4,5-DIHYDRO-1H-AZEPINO[5,4,3-CD]INDOL-6(3H)-ONE; 6H-Pyrrolo[4,3,2-ef][2]benzazepin-6-one,8-fluoro-1,3,4,5-tetrahydro-2-[4-[(methylamino)methyl]phenyl]-; 8-fluoro-2-(4-methylaminomethyl-phenyl)-1,3,4,5-tetrahydro-azepino[5,4,3-cd]indol-6-one
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CID: 9931954
TTD: D01SHZ
DrugBank: DB12332
 Compound Name Melphalan flufenamide Approved [17]
Synonyms
J-1; Dipeptide-conjugated melphalan prodrug (iv formulation, ovary tumor), Oncopeptides
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CID: 9935639
TTD: D01HPY
 Compound Name Nivolumab Approved [2]
External Link
TTD: D00GOV
 Compound Name Ofranergene obadenovec Phase 3 [18]
Synonyms
VB-111
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TTD: DU60ND
 Compound Name Batiraxcept Phase 3 [19]
Synonyms
AVB-S6-500
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TTD: DDRX30
 Compound Name Trebananib Phase 3 [20]
External Link
TTD: D9NL3R
 Compound Name Nemvaleukin alfa Phase 3 [21]
External Link
TTD: D1I0LQ
 Compound Name RRx-001 Phase 2 [2]
Synonyms
925206-65-1; 2-BROMO-1-(3,3-DINITROAZETIDIN-1-YL)ETHAN-1-ONE; UNII-7RPW6SU9SC; 2-Bromo-1-(3,3-dinitroazetidin-1-yl)ethanone; 7RPW6SU9SC; RRx001; Ethanone, 2-bromo-1-(3,3-dinitro-1-azetidinyl)-; SCHEMBL2249018; CHEMBL3526802; MolPort-044-559-098; EX-A2006; BCP19228; 1-bromoacetyl-3,3-dinitroazetidine; ZINC34805177; s8405; DB12060; CS-5286; HY-16438; AS-53015
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CID: 15950826
TTD: D0X8TS
DrugBank: DB12060
 Compound Name Picoplatin Phase 3 [22]
Synonyms
AMD 473; JM-473; ZD0473; (SP-4-3)-Amminedichloro(2-methylpyridine)platinium; Platinum, amminedichloro(2-methylpyridine)-, (SP-4-3)-; Picoplatin [INN:BAN]; UNII-B5TAN0L720; ZD 0473; AC1L42P3; B5TAN0L720; DB04874; Amminedichloro(2-methylpyridine)platinium; AN-30599; LS-184068; J-011604; azane; 2-methylpyridine; dichloride
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CID: 177358
TTD: D0T7GV
DrugBank: DB04874
 Compound Name VB-111 Phase 3 [2]
External Link
TTD: D0S4LV
 Compound Name Upifitamab rilsodotin Phase 3 [23]
External Link
TTD: D0QFD2
 Compound Name ABT-888 Phase 3 [2]
Synonyms
Veliparib; 912444-00-9; ABT 888; ABT-888 (Veliparib); Veliparib (ABT-888); ABT888; UNII-01O4K0631N; 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide; CHEBI:62880; 2-[(R)-2-methylpyrrolidin-2-yl]-1H-benzimidazole-4-carboxamide; (R)-2-(2-methylpyrrolidin-2-yl)-1H-benzo[d]imidazole-4-carboxamide; 01O4K0631N; 2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4-; (2r)-2-(7-Carbamoyl-1h-Benzimidazol-2-Yl)-2-Methylpyrrolidinium; Veliparib dihydrochloride
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CID: 45480520
TTD: D0Q7UD
 Compound Name Rubraca rucaparib Phase 3 [2]
External Link
TTD: D0NA8B
 Compound Name Masitinib Phase 3 [2]
Synonyms
790299-79-5; AB1010; Masatinib; Masitinib (AB1010); Masivet; AB-1010; AB 1010; UNII-M59NC4E26P; Masitinib [INN]; M59NC4E26P; 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-thiazolyl]amino]phenyl]benzamide; CHEMBL1908391; CHEBI:63450; Masitinib (INN); N-(4-Methyl-3-((4-(pyridin-3-yl)thiazol-2-yl)amino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide; Q-201339; C28H30N6OS; N-(4-methyl-3-(4-(pyridin-3-yl)thiazol-2-ylamino)phenyl)-4-((4-methylpiperazin-1-yl)methyl)benzamide
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CID: 10074640
TTD: D0MW0N
DrugBank: DB11526
 Compound Name Galinpepimut-S Phase 3 [24]
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TTD: D0M9OO
 Compound Name SNDX-275 Phase 3 [2]
Synonyms
Entinostat; Histone Deacetylase Inhibitor I; IN1470; MS 275; SNDX 275; MS 27-275; Ms-275; Entinostat (USAN/INN); MS-27-275; Pyridin-3-ylmethyl 4-(2-aminophenylcarbamoyl)benzylcarbamate; Pyridin-3-ylmethyl N-[[4-[(2-aminophenyl)carbamoyl]phenyl]methyl]carbamate; Pyridin-3-ylmethyl {4-[(2-aminophenyl)carbamoyl]benzyl}carbamate; Pyridin-3-ylmethyl{4-[(2-aminophenyl)carbamoyl]benzyl}carbamate; Carbamic acid, [[4-[[(2-aminophenyl)amino]carbonyl]phenyl] methyl]-, 3-pyridinylmethyl ester; Carbamic acid, [[4-[[(2-aminophenyl)carbaonyl]phenyl]methyl]-, 3-pyridinylmethyl ester; Entinostat, SNDX-275, MS-27-275, MS-275; N-(2-Aminophenyl)-4-[N-(pyridin-3-yl-methoxycarbonyl)aminomethyl]benzamide; N-(2-aminophenyl)-4-(N-(pyridin-3-ylmethoxycarbonyl)aminomethyl)benzamide; Carbamic acid, ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)-, 3-pyridinylmethyl ester; 3-Pyridinylmethyl ((4-(((2-aminophenyl)amino)carbonyl)phenyl)methyl)carbamate
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CID: 4261
TTD: D0M8FD
DrugBank: DB11841
 Compound Name acelarin Phase 2 [2]
Synonyms
NUC-1031
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CID: 11169170
TTD: D0M1IN
DrugBank: DB15057
 Compound Name Glufosfamide Phase 3 [5]
Synonyms
Glucosylifostamide mustard; D 19575; D-19575; Glc-IPM; Glucosyl-ifosfamide mustard; Beta-D-Glucopyranose 1-(N,N'-bis(2-chloroethyl)phosphorodiamidate; Beta-D-Glucopyranose, 1-(N,N'-bis(2-chloroethyl)phosphorodiamidate); (2S,3R,4S,5S,6R)-2-bis(2-chloroethylamino)phosphoryloxy-6-(hydroxymethyl)oxane-3,4,5-triol
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CID: 123628
TTD: D0L9IA
DrugBank: DB06177
 Compound Name PM1183 Phase 3 [8]
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TTD: D0K6AL
 Compound Name Amonafide Phase 3 [25]
Synonyms
Quinamed (TN)
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CID: 50515
TTD: D0HR7P
DrugBank: DB05022
 Compound Name Etirinotecan pegol Phase 2 [8]
Synonyms
NKTR-102
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CID: 56935717
TTD: D0H5IZ
 Compound Name INCB24360 Phase 2 [2]
Synonyms
Epacadostat
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CID: 135564890
TTD: D0G7MV
DrugBank: DB11717
 Compound Name AL3818 Phase 1/2 [2]
Synonyms
Anlotinib; 1058156-90-3; UNII-GKF8S4C432; GKF8S4C432; AL-3818; SCHEMBL2063386; GTPL9601; KSMZEXLVHXZPEF-UHFFFAOYSA-N; MolPort-044-567-604; ZINC117924202; AKOS030526233; DB11885; CS-5396; AL 3818; HY-19716; 1-[[4-[(4-fluoro-2-methyl-1H-indol-5-yl)oxy]-6-methoxyquinolin-7-yl]oxymethyl]cyclopropan-1-amine; 1-((4-(4-fluoro-2-methyl-1h-indol-5-yloxy)-6-methoxyquinolin-7-yloxy)methyl)cyclopropan-amine; Cyclopropanamine, 1-(((4-((4-fluoro-2-methyl-1H-indol-5-yl)oxy)-6-methoxy-7-quinolinyl)oxy)methyl)-
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CID: 25017411
TTD: D0G2CG
DrugBank: DB11885
 Compound Name Sapacitabine Phase 3 [2]
Synonyms
CYC682
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CID: 153970
TTD: D0D4RF
DrugBank: DB06365
 Compound Name Pelareorep Phase 2 [8]
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TTD: D0BF8Y
 Compound Name Opdivo + Yervoynivolumab + ipilimumab Phase 1/2 [2]
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TTD: D08TBK
 Compound Name Epothilon Phase 3 [5]
External Link
TTD: D07WPE
 Compound Name Oregovomab Phase 3 [26]
External Link
TTD: D07HUW
 Compound Name Farletuzumab Phase 3 [27]
External Link
TTD: D06XVN
 Compound Name DCVax-Ovarian Phase 3 [2]
Synonyms
DCVax-L; Dendritic cell-based immunotherapy (ovarian cancer), Northwest Biotherapeutics
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TTD: D02XEI
 Compound Name MK-8109 Phase 3 [28]
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TTD: D02TJT
 Compound Name Karenitecin Phase 3 [29]
Synonyms
Karenitecin (TN)
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CID: 148202
TTD: D02CZK
DrugBank: DB05806
 Compound Name TRC105 Phase 2 [30]
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TTD: D00YQI
 Compound Name SNS-595 Phase 3 [5]
Synonyms
Voreloxin; Vosaroxin; AG 7352; SNS 595; SPC 595; AG 7352 (TN); AG-7352; SNS 595 (TN); SPC 595 (TN); SPC-595; Voreloxin (TN); Voreloxin (USAN); SNS-595 (TN); 1,4-Dihydro-7-(3-methoxy-4-methylamino-1-pyrrolidinyl)-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acid
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CID: 9952884
TTD: D00NVM
DrugBank: DB11999
 Compound Name MK-4827 Phase 3 [31]
Synonyms
1038915-60-4; (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide; UNII-HMC2H89N35; HMC2H89N35; CHEMBL1094636; 2-{4-[(3s)-piperidin-3-yl]phenyl}-2h-indazole-7-carboxamide; MK4827; MK 4827; Niraparib [USAN:INN]; 2-{4-[(3S)-piperidin-3-yl]phenyl}indazole-7-carboxamide; 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide; MK 4827 (Base); Niraparib (USAN); Zejula (TN); MK-4827(Niraparib); SCHEMBL1421875; GTPL8275; CTK8B9123; EX-A290; DTXSID50146129; MolPort-023-219-142; ZINC43206370; BDBM50316226
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CID: 24958200
TTD: D00BMF
DrugBank: DB11793
 Compound Name EC20 Phase 3 [32]
Synonyms
Technetium Tc-99m etarfolatide
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CID: 135428923
TTD: D00BHL
 Compound Name Abagovomab Phase 2/3 [33]
External Link
TTD: D00KGB
 Compound Name Mecbotamab vedotin Phase 2 [34]
Synonyms
HTBA3011; HTBA3012
    Click to Show/Hide
External Link
TTD: DYI4L2
 Compound Name GEN-1 Phase 2 [2]
External Link
TTD: DRT2P7
 Compound Name Stenoparib Phase 2 [35]
External Link
TTD: DP48WE
 Compound Name DKN-01 Phase 2 [2]
External Link
TTD: DMF73Z
 Compound Name EP-100 Phase 2 [2]
External Link
TTD: DL76CW
 Compound Name EP0057 Phase 2 [36]
Synonyms
CRLX101
    Click to Show/Hide
External Link
TTD: DGD93X
 Compound Name BNT141 Phase 2 [37]
External Link
TTD: DFZ19J
 Compound Name TJ004309 Phase 2 [38]
External Link
TTD: DFYL50
 Compound Name Maveropepimut-S Phase 2 [39]
External Link
TTD: DFS8A7
 Compound Name PF-07901801 Phase 2 [40]
Synonyms
maplirpacept
    Click to Show/Hide
External Link
TTD: D6SJ0B
 Compound Name SPL-108 Phase 2 [2]
External Link
TTD: D2C0DY
 Compound Name VS-6063 Phase 2 [2]
Synonyms
Defactinib hydrochloride; 1073160-26-5; Defactinib (hydrochloride); UNII-L2S469LM49; Defactinib hydrochloride [USAN]; L2S469LM49; Defactinib hydrochloride (USAN); Benzamide, N-methyl-4-[[4-[[[3-[methyl(methylsulfonyl)amino]-2-pyrazinyl]methyl]amino]-5-(trifluoromethyl)-2-pyrimidinyl]amino]-, hydrochloride; Defactinib HCl; Benzamide, N-methyl-4-((4-(((3-(methyl(methylsulfonyl)amino)-2-pyrazinyl)methyl)amino)-5-(trifluoromethyl)-2-pyrimidinyl)amino)-, hydrochloride (1:1); Benzamide, N-methyl-4-[[4-[[[3-[methyl(methylsu
    Click to Show/Hide
External Link
CID: 25117126
TTD: D0Y1UO
DrugBank: DB12282
 Compound Name PTX-200 Phase 2 [2]
Synonyms
Plant-derived antiparkinsonian, Phytrix
    Click to Show/Hide
External Link
TTD: D0X7CV
 Compound Name Mirvetuximab soratansine Phase 2 [8]
External Link
TTD: D0V9EX
 Compound Name Ovapuldencel-T Phase 2 [2]
External Link
TTD: D0TR3Y
 Compound Name MUC-1 cancer vaccine Phase 2 [41]
Synonyms
CVac (TN)
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External Link
TTD: D0T5ES
 Compound Name FANG vaccine Phase 3 [42]
Synonyms
FANG (TN)
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External Link
TTD: D0Q4NX
 Compound Name Ispinesib Phase 2 [43]
Synonyms
SB-715992; Ispinesib (SB-715992 /CK0238273); SB-715992, CK0238273,Ispinesib; N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxoquinazolin-2-yl)-2-methylpropyl]-4-methylbenzamide
    Click to Show/Hide
External Link
CID: 6851740
TTD: D0PW4N
DrugBank: DB06188
 Compound Name EGEN-001 Phase 2 [44]
External Link
TTD: D0OS7K
 Compound Name CRLX101 Phase 2 [2]
External Link
CID: 184196
TTD: D0ND9T
 Compound Name Folate binding protein vaccine Phase 2 [45]
External Link
TTD: D0M7YU
 Compound Name RO-5126766 Phase 2 [46]
Synonyms
VS-6766; CH-5126766; Dual Raf/MEK protein kinase inhibitor (cancer), Roche
    Click to Show/Hide
External Link
CID: 16719221
TTD: D0M6BD
DrugBank: DB15254
 Compound Name TPIV200 Phase 2 [24]
External Link
TTD: D0LB8Z
 Compound Name BBI503 Phase 2 [47]
External Link
CID: 25190990
TTD: D0L9XF
DrugBank: DB14866
 Compound Name Varlilumab Phase 2 [2]
External Link
TTD: D0KV3M
 Compound Name Kevetrin Phase 2 [2]
External Link
CID: 437740
TTD: D0K7DV
DrugBank: DB13010
 Compound Name OTL38 Phase 2 [8]
External Link
TTD: D0I9IL
 Compound Name NanoPac Phase 2 [2]
External Link
TTD: D0FZ7Q
 Compound Name Sagopilone Phase 2 [48]
Synonyms
ZK-EPO; 305841-29-6; UNII-KY72JU32FO; KY72JU32FO; DE-03757; ZK-219477; EPO-477; SH-Y03757A; ZK epothilone; Sagopilone [USAN:INN]; Sagopilone (USAN/INN); SCHEMBL423579; CHEMBL2304041; SH Y03757A; Bay 86-5302; ZINC3964449; DB12391; SH-Y-03757; BAY-86-5302; AN-28960; DE 03757; ZK 219477; D09721; 841S296; (1S,3S,7S,10R,11S,12S,16R)-10-allyl-7,11-dihydroxy-8,8,12,16-tetramethyl-3-(2-methyl-1,3-benzothiazol-5-yl)-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
    Click to Show/Hide
External Link
CID: 11284169
TTD: D0F6YW
DrugBank: DB12391
 Compound Name PMID27841036-Compound-37 Phase 2 [49]
Synonyms
2X-121
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External Link
CID: 135565981
TTD: D0F5TD
 Compound Name BGB-290 Phase 2 [50]
Synonyms
Pamiparib
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External Link
CID: 135565554
TTD: D0D9IQ
DrugBank: DB14769
 Compound Name TLPLDC Phase 2 [24]
External Link
TTD: D0D0DH
 Compound Name Anetumab ravtansine Phase 2 [2]
Synonyms
Mesothelin-ADC
    Click to Show/Hide
External Link
TTD: D0CN9D
 Compound Name OGX-427 Phase 2 [51]
External Link
CID: 71710946
TTD: D0AX1N
 Compound Name ZW25 Phase 1 [2]
Synonyms
Zanidatamab
    Click to Show/Hide
External Link
TTD: D0AJ9V
 Compound Name CDX-1401 Phase 2 [2]
External Link
TTD: D09TCY
 Compound Name CA4P Phase 2 [8]
Synonyms
Fosbretabulin disodium; 168555-66-6; Combretastatin A4 disodium phosphate; CA4DP; Fosbretabulin (disodium); Zybrestat; UNII-702RHR475O; Combretastatin A4 Phosphate Disodium Salt; Fosbretabulin disodium [USAN]; 702RHR475O; Combretastatin A-4 phosphate; Fosbretabulin disodium (USAN); CHEMBL289351; Fosbretabulin (Combretastatin A4 Phosphate (CA4P)) Disodium; AC1OCF9S; Fosbretabulin Disodium Salt; CA-4P; CA 4P; SCHEMBL321426; C18H19O8P.2Na; MolPort-006-823-175; ACT03122; 3559AH; s7204; AKOS027327946; BCP9000542; CS-1484; NSC-752293; Fosbr
    Click to Show/Hide
External Link
CID: 100154
TTD: D09OKZ
DrugBank: DB05284
 Compound Name Dendritic cell vaccine Phase 2 [52]
Synonyms
Dendritic cell vaccine, University of Bonn; Human telomerase reverse transcriptase (hTERT)-pulsed dendritic cells (cancer), University of Bonn
    Click to Show/Hide
External Link
TTD: D09NFW
 Compound Name LY2606368 Phase 2 [2]
Synonyms
prexasertib; 1234015-52-1; UNII-820NH671E6; LY-2606368; 820NH671E6; Prexasertib [USAN]; 5-((5-(2-(3-aminopropoxy)-6-methoxyphenyl)-1H-pyrazol-3-yl)amino)pyrazine-2-carbonitrile; 5-({5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl}amino)pyrazine-2-carbonitrile; 5-[[5-[2-(3-aminopropoxy)-6-methoxyphenyl]-1H-pyrazol-3-yl]amino]pyrazine-2-carbonitrile; SCHEMBL1975451; GTPL9549; SCHEMBL19457660; SCHEMBL18989301; CHEMBL3544911; EX-A758; DOTGPNHGTYJDEP-UHFFFAOYSA-N; AOB87325; ZINC95837013
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External Link
CID: 46700756
TTD: D08UUL
DrugBank: DB12008
 Compound Name GSK3377794 Phase 2 [2]
External Link
TTD: D08FWJ
 Compound Name Melphalan Approved [53]
External Link
CID: 460612
TTD: D06XES
DrugBank: DB01042
 Compound Name MEDI-546 Phase 2 [54]
External Link
TTD: D06TME
 Compound Name RG-7599 Phase 2 [55]
Synonyms
DNIB-0600A; Antibody-drug conjugate (NSCLC/ovarian cancer), Genentech
    Click to Show/Hide
External Link
TTD: D05YYP
 Compound Name EP-201 Phase 2 [24]
Synonyms
Chissonox 201; Unox epoxide 201; Unox 201; Epoxide-201; EP 201; 141-37-7; CCRIS 279; NSC 61273; BRN 0246264; MLS002638023; CHEBI:82463; 3,4-epoxy-6-methylcyclohexylmethyl-3,4-epoxy-6-methylcyclohexanecarboxylate; Epoxide 201; 6-Methyl-3,4-epoxycyclohexylmethyl 6-methyl-3,4-epoxycyclohexane carboxylate; 3,4-Epoxy-6-methylcyclohexylmethyl-3,4-epoxy-6-methylcyclohexane carboxylate; 3,4-Epoxy-6-methylcyclohexylmethyl-3',4'-epoxy-6'-methylcyclohexane carboxylate; 3,4-Epoxy-6-methylcyclohexylmethyl 3,4-epoxy-6-methylcyclohexanec
    Click to Show/Hide
External Link
CID: 61094
TTD: D05GYU
 Compound Name APR-246 Phase 2 [2]
Synonyms
Eprenetapopt
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External Link
CID: 52918385
TTD: D03XTY
DrugBank: DB11684
 Compound Name Tigatuzumab Phase 2 [56]
External Link
TTD: D03LTO
 Compound Name CRS-207 Phase 2 [24]
External Link
TTD: D02WSB
 Compound Name MK-1775 Phase 2 [57]
Synonyms
955365-80-7; Adavosertib; MK1775; MK 1775; UNII-K2T6HJX3I3; AZD 1775; AZD-1775; AZD1775; 2-allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one; K2T6HJX3I3; 1-[6-(2-hydroxypropan-2-yl)pyridin-2-yl]-6-[4-(4-methylpiperazin-1-yl)anilino]-2-prop-2-enylpyrazolo[3,4-d]pyrimidin-3-one; 2-Allyl-1-(6-(2-hydroxypropan-2-yl)pyridin-2-yl)-6-((4-(4-methylpiperazin-1-yl)phenyl)amino)-1H-pyrazolo[3,4-d]pyrimidin-3(2H)-one; AK-99219
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External Link
CID: 24856436
TTD: D02KKA
DrugBank: DB11740
 Compound Name CP-547632 Phase 2 [58]
Synonyms
BFF; CP 547632; CP-547,632; 3-(4-Bromo-2,6-difluorobenzyloxy)-5-(3-(4-pyrrolidin-1-ylbutyl)ureido)isothiazole-4-carboxylic acid amide
    Click to Show/Hide
External Link
CID: 9811611
TTD: D00YPR
DrugBank: DB12962
 Compound Name Motolimid Phase 2 [8]
External Link
TTD: D00OYC
 Compound Name TC-210 Phase 1/2 [59]
External Link
TTD: DX6O9V
 Compound Name REGN5668 Phase 1/2 [60]
External Link
TTD: DT1R9E
 Compound Name TC-510 Phase 1/2 [61]
External Link
TTD: DJA64B
 Compound Name XMT-1592 Phase 1/2 [62]
External Link
TTD: DDL79K
 Compound Name GL-ONC1 Phase 2 [63]
Synonyms
olvimulogene nanivacirepvec
    Click to Show/Hide
External Link
TTD: DA6OU0
 Compound Name LY2940680 Phase 1/2 [2]
Synonyms
1258861-20-9; Taladegib; LY-2940680; UNII-QY8BWX1LJ5; 4-Fluoro-N-methyl-N-(1-(4-(1-methyl-1H-pyrazol-5-yl)phthalazin-1-yl)piperidin-4-yl)-2-(trifluoromethyl)benzamide; QY8BWX1LJ5; Taladegib (LY2940680); LY 2940680; 4-fluoro-n-methyl-n-(1-(4-(1-methyl-1h-pyrazol-5-yl)-1-phthalazinyl)-4-piperidinyl)-2-(trifluoromethyl)benzamide; 4-Fluoro-N-Methyl-N-{1-[4-(1-Methyl-1h-Pyrazol-5-Yl)phthalazin-1-Yl]piperidin-4-Yl}-2-(Trifluoromethyl)benzamide; Taladegib [USAN:INN]
    Click to Show/Hide
External Link
CID: 49848070
TTD: D0W0SL
DrugBank: DB12550
 Compound Name Her-2/neu vaccine Phase 1/2 [64]
External Link
TTD: D0U3FP
 Compound Name NY-ESO-TCR Phase 1/2 [65]
External Link
TTD: D0TN1N
 Compound Name GALE-302 Phase 1/2 [2]
External Link
TTD: D0T7MZ
 Compound Name DPX-survivac cancer vaccine Phase 1/2 [66]
External Link
TTD: D0T2IF
 Compound Name REGN4018 Phase 1/2 [67]
External Link
TTD: D0LA9K
 Compound Name GALE-301 + GALE-302 Phase 1/2 [24]
External Link
TTD: D0IW4E
 Compound Name Anti-C-met CAR-T cells Phase 1/2 [68]
External Link
TTD: D0A3OE
 Compound Name CDX-014 Phase 1/2 [2]
External Link
TTD: D09WXY
 Compound Name O-Vax Phase 1/2 [69]
Synonyms
AC vaccine (ovarian cancer), AVAX
    Click to Show/Hide
External Link
TTD: D09GRH
 Compound Name Anti-HER2 CAR-T Phase 1/2 [70]
External Link
TTD: D08QZH
 Compound Name NT-501 CNTF Phase 1/2 [71]
External Link
TTD: D07GWZ
 Compound Name Phenoxodiol Phase 1/2 [72]
Synonyms
Dehydroequol; Idronoxil; Haginin E; NV 06; NV-06; Idronoxil (USAN/INN); 2H-1-benzopyran-7-0,1,3-(4-hydroxyphenyl); 3-(4-Hydroxyphenyl)-2H-1-benzopyran-7-ol; 3-(4-Hydroxyphenyl)-2H-chromen-7-ol; 7-hydroxy-3-hydroxyphenyl-1H-benzopyran
    Click to Show/Hide
External Link
CID: 219100
TTD: D03YOS
DrugBank: DB04915
 Compound Name GALE-301 Phase 2 [24]
External Link
TTD: D02DEZ
 Compound Name IL-2/gene-modified lymphocytes Phase 1/2 [73]
External Link
TTD: D01VWB
 Compound Name Ovarian dendritic cell-based vaccine Phase 1/2 [74]
External Link
TTD: D01EMD
 Compound Name Anti-mesothelin CAR transduced PBL Phase 1/2 [75]
External Link
TTD: D00YXG
 Compound Name ONCOS-102 Phase 1/2 [2]
Synonyms
CGTG-102
    Click to Show/Hide
External Link
TTD: D00NBW
 Compound Name BNT115 Phase 1 [76]
External Link
TTD: DT3OZ4
 Compound Name MEDI3617 Phase 1 [77]
External Link
TTD: DP7J0Z
 Compound Name SL-172154 Phase 1 [78]
External Link
TTD: DKUF26
 Compound Name INKmune Phase 1 [79]
External Link
TTD: DJ9H4F
 Compound Name DeTIL-0255 Phase 1 [80]
External Link
TTD: DJ3QK6
 Compound Name DS-6000 Phase 1 [81]
External Link
TTD: DISJ28
 Compound Name MCY-M11 Phase 1 [82]
External Link
TTD: D8EIB7
 Compound Name IMT1012 Phase 1 [83]
External Link
TTD: D7W6SO
 Compound Name mRNA-2416 Phase 1 [84]
Synonyms
mRNA-OX40L
    Click to Show/Hide
External Link
TTD: D70SHJ
 Compound Name TG4050 Phase 1 [85]
External Link
TTD: D6CV1Q
 Compound Name GRN-300 Phase 1 [86]
External Link
TTD: D40NQW
 Compound Name ITIL-306 Phase 1 [87]
External Link
TTD: D3MGD9
 Compound Name STRO-002 Phase 1 [88]
External Link
TTD: D10GPJ
 Compound Name Ipafricept Phase 1 [89]
External Link
TTD: D0Z6AM
 Compound Name IMT-1012 immunotherapeutic vaccine Phase 1 [90]
External Link
TTD: D0Y9VC
 Compound Name STM 434 Phase 1 [8]
External Link
TTD: D0X6DC
 Compound Name Mibefradil Withdrawn from market [91]
Synonyms
Mibefradil (Cytostatic Checkpoint Therapy, ovarian cancer); Mibefradil (Cytostatic Checkpoint Therapy, ovarian cancer), Tau Therapeutics; Calcium T-channel inhibitor (Cytostatic Checkpoint Therapy, ovarian cancer), Tau Therapeutics
    Click to Show/Hide
External Link
CID: 60663
TTD: D0W8XT
DrugBank: DB01388
 Compound Name RG7882 Phase 1 [92]
External Link
TTD: D0V7QW
 Compound Name MOv19-BBz CAR T cells Phase 1 [93]
External Link
TTD: D0T7CR
 Compound Name SC-003 Phase 1 [2]
External Link
TTD: D0SZ2G
 Compound Name KHK-2866 Phase 1 [94]
External Link
TTD: D0S4KJ
 Compound Name PUMVC3-hIGFBP-2 Phase 1 [95]
Synonyms
IGFBP-2 DNA plasmid vaccine (intradermal, ovarian cancer); IGFBP-2 DNA plasmid vaccine (intradermal, ovarian cancer), Fred Hutchinson
    Click to Show/Hide
External Link
TTD: D0O9FH
 Compound Name Anti-hCD70 CAR transduced PBL Phase 1 [96]
External Link
TTD: D0JO9M
 Compound Name Prolanta Phase 1 [2]
External Link
TTD: D0J1OG
 Compound Name JCAR020 Phase 1 [65]
External Link
TTD: D0I0FA
 Compound Name COTI-2 Phase 1 [2]
Synonyms
UNII-2BTA1O65BR; 2BTA1O65BR; 1039455-84-9; ZINC114475331; CS-8156; HY-19896; 1-Piperazinecarbothioic acid, 4-(2-pyridinyl)-, 2-(6,7-dihydro-8(5H)-quinolinylidene)hydrazide
    Click to Show/Hide
External Link
CID: 91810660
TTD: D0G8CU
 Compound Name Anti-meso-CAR vector transduced T cells Phase 1 [97]
External Link
TTD: D0G4GY
 Compound Name Cantrixil Phase 1 [2]
Synonyms
UNII-5DVS457HEG; 5DVS457HEG; SCHEMBL19410294; TRX-E-002-1; cis-4-(p-hydroxyphenyl)-7,4'-dihydroxy-3',5'-dimethoxy-8-methylisoflavan; (+)-cis-4-(Para-hydroxyphenyl)-7,4-dihydroxy-3,5-dimethoxy-8-methylisoflavan; 1803036-93-2
    Click to Show/Hide
External Link
CID: 129851403
TTD: D0FL2K
 Compound Name Iboctadekin + Doxil Phase 1 [98]
External Link
CID: 5478883
TTD: D0F3PU
 Compound Name FATE-NK100 Phase 1 [2]
External Link
TTD: D0A9GE
 Compound Name Iboctadekin Phase 1 [99]
External Link
TTD: D0A8HN
 Compound Name Anti-CD133-CAR vector-transduced T cells Phase 1 [100]
External Link
TTD: D09HRH
 Compound Name Hu-CART meso cells Phase 1 [101]
External Link
TTD: D07YPB
 Compound Name PTC596 Phase 1 [2]
External Link
TTD: D07EKK
 Compound Name SOR-C13 Phase 1 [102]
External Link
CID: 121596688
TTD: D06UWF
DrugBank: DB15366
 Compound Name AE-O Phase 1 [103]
Synonyms
Ovarian vaccine, Generex
    Click to Show/Hide
External Link
TTD: D05MEP
 Compound Name E 7974 Phase 1 [5]
Synonyms
26510-52-1; ethyl 3-oxo-3-(pyridin-2-yl)propanoate; Ethyl picolinoylacetate; ethyl 3-oxo-3-(2-pyridyl)propionate; ethyl 3-oxo-3-pyridin-2-ylpropanoate; ethyl 3-oxo-3-(2-pyridinyl)propanoate; 3-Oxo-3-(2-pyridyl)propionic acid ethyl ester; Ethyl picolinoylacetate, 95%; ethyl 3-oxo-3-(2-pyridyl)propanoate; PubChem11088; ethyl-2-pyridoyl acetate; AC1MC5MX; AC1Q34ND; SCHEMBL601821; CHEMBL2035673; CTK4F8033; DTXSID30371376; MolPort-001-769-152; FQHXWZMJALFSJJ-UHFFFAOYSA-N; ZINC153764; Ethyl picolinoylacetate, AldrichCPR; STL131872
    Click to Show/Hide
External Link
CID: 10127315
TTD: D05HBZ
 Compound Name DMUC-5754A Phase 1 [104]
External Link
TTD: D04ZIZ
 Compound Name Alvespimycin hydrochloride Phase 1 [105]
Synonyms
Alvespimycin hydrochloride (USAN); 17-DMAG; 17-Desmethoxy-17-N,N-dimethylaminoethylamino-geldanamycin, HCl; 17-N,N-Dimethylaminoethylamino-17-demethoxy-geldanamycin, HCl; 17DMAG; 17DMAG, Alvespimycin, KOS-1022, NSC 707545, 17-DMAG
    Click to Show/Hide
External Link
CID: 9852573
TTD: D03LRU
 Compound Name Navicixizumab Phase 1 [65]
External Link
TTD: D00IVN
 Compound Name AR-A014418 Patented [106]
Synonyms
487021-52-3; GSK-3beta Inhibitor VIII; 1-(4-methoxybenzyl)-3-(5-nitrothiazol-2-yl)urea; 1-[(4-methoxyphenyl)methyl]-3-(5-nitro-1,3-thiazol-2-yl)urea; A Inhibitor VIII; N-(4-METHOXYBENZYL)-N'-(5-NITRO-1,3-THIAZOL-2-YL)UREA; UNII-87KSH90Q6D; AR-AO 14418; SN 4521; AR-A 014418; CHEMBL259850; 87KSH90Q6D; N-[(4-Methoxyphenyl)methyl]-N'-(5-nitro-2-thiazolyl)urea; AK175829; C12H12N4O4S; N-(4-Methoxybenzyl)-N& -(5-nitro-1,3-thiazol-2-yl)urea; AR 014418; GSK 3be
    Click to Show/Hide
External Link
CID: 448014
TTD: D0A3MV
DrugBank: DB01950
 Compound Name R1549 Discontinued in Phase 3 [107]
External Link
TTD: D0VE6X
 Compound Name Tanomastat Discontinued in Phase 3 [108]
Synonyms
Tanomastat (USAN/INN); (2S)-4-[4-(4-chlorophenyl)phenyl]-4-oxo-2-(phenylsulfanylmethyl)butanoic acid
    Click to Show/Hide
External Link
CID: 6918336
TTD: D0Q1CD
DrugBank: DB06276
 Compound Name IDM-1 Discontinued in Phase 3 [109]
Synonyms
Osidem
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External Link
TTD: D02YWW
 Compound Name Lurtotecan Discontinued in Phase 2 [110]
Synonyms
OSI-211; Lurtotecan [INN]; 149882-10-0; UNII-4J1L80T08I; OSI 211; NX 211; GG 211; Gi 147211; 4J1L80T08I; C28H30N4O6; CHEMBL341028; 11H-1,4-Dioxino(2,3-g)pyrano(3',4':6,7)indolizino(1,2-b)quinoline-9,12(8H,14H)-dione, 8-ethyl-2,3-dihydro-8-hydroxy-15-((4-methyl-1-piperazinyl)methyl)-, (8S)-; GI-147211C; lurtotecan liposome; AC1L1U8C; SCHEMBL19208; CHEMBL305666; DTXSID30164422; GG-211; ZINC22010625; NX-211; GW-211; BDBM50036130; DB12222; LS-173358; Lurtotecan dihydrochloride; GI 147211C; GG-147211C; GI-147211; GI-147211A; GL-147211C; Liposomal lurtotecan
    Click to Show/Hide
External Link
CID: 60956
TTD: D0Q7FC
DrugBank: DB12222
 Compound Name AGS-8M4 Discontinued in Phase 2 [111]
Synonyms
AGS-8 MAb, Agensys, AGS8M4, ASP-6183
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External Link
TTD: D05DBZ
 Compound Name Biricodar Discontinued in Phase 2 [112]
Synonyms
Incel; Biricodar [INN]; Vx 710; Incel (TN); 1,7-dipyridin-3-ylheptan-4-yl (2S)-1-[2-oxo-2-(3,4,5-trimethoxyphenyl)acetyl]piperidine-2-carboxylate
    Click to Show/Hide
External Link
CID: 3037617
TTD: D02VJY
DrugBank: DB04851
 Compound Name Onyvax-O Discontinued in Phase 1 [113]
External Link
TTD: D0XT5F
 Compound Name RG7458 Discontinued in Phase 1 [114]
External Link
TTD: D0G9ZJ
 Compound Name RG7600 Discontinued in Phase 1 [115]
External Link
TTD: D04TYP
 Compound Name S-8184 Preclinical [116]
External Link
TTD: D0X4UH
 Compound Name 111In-OC-125 F(ab1/2)-DTPA Terminated [117]
Synonyms
Indimacis 125; Indium-111-OC-125 F(ab1/2)-DTPA
    Click to Show/Hide
External Link
TTD: D07PMU
 Compound Name HumaRAD-OV Investigative [118]
Synonyms
HumaRAD88BV59; KSB-310
    Click to Show/Hide
External Link
TTD: D0Z1CQ
 Compound Name FOLIGO 002 Investigative [118]
External Link
TTD: D0Y6QX
 Compound Name HS-210 Investigative [118]
Synonyms
HS-01; Endoplasmin modulator (ovary tumor, HeatShock/fusion protein/antigen), Heat Biologics; Gp-96-Ig + unspecified tumorantigen secreting live cell vaccine (ovary tumor, HeatShock), Heat Biologics
    Click to Show/Hide
External Link
TTD: D0XK6P
 Compound Name CGEN-991 Investigative [118]
Synonyms
Anti-CGEN-991 antibody (ovarian cancer); CGEN-991 (ovarian cancer), Compugen; Anti-CGEN-991 antibody (ovarian cancer), Compugen
    Click to Show/Hide
External Link
TTD: D0V1TV
 Compound Name FabOvar Investigative [118]
Synonyms
Alpha-folate receptor-targeting I131-labeled mAb fragment (ip, ovarian carcinoma), Advanced Accelerator Applications; Alpha-folate receptor-targeting I131-labeled mAb fragment (ip, ovarian carcinoma), Dompe
    Click to Show/Hide
External Link
TTD: D0S6OY
 Compound Name ALVAC-CEA/hB7.1 Investigative [118]
External Link
TTD: D0Q2IV
 Compound Name MX-35 Investigative [118]
Synonyms
Monoclonal antibody (ovarian cancer), Recepta
    Click to Show/Hide
External Link
TTD: D0P6YL
 Compound Name 6-(4-CHLOROPHENYL)-7-(2,4-DICHLOROPHENYL)-N-(HYDROXYMETHYL)-1,2,2-TRIMETHYL-1,2,3,4-TETRAHYDRO-1,8-NAPHTHYRIDINE-4-CARBOXAMIDE (ENANTIOMERIC MIX) Investigative [119]
Synonyms
CHEMBL1082330; BDBM50320180
    Click to Show/Hide
External Link
CID: 46891330
TTD: D0OQ5H
 Compound Name ET-006 Investigative [118]
External Link
TTD: D0L3LO
 Compound Name AB-3D3 Investigative [118]
Synonyms
AB-0447a; KAAG1-targeting mAb (ovarian cancer), Alethia; KAAG1-targeting monoclonal antibody (ovarian cancer), Alethia; Kidney associated antigen 1-targeting mAb (ovarian cancer), Alethia; Kidney associated antigen 1-targeting monoclonal antibody (ovarian cancer), Alethia; AB-0447-targeting monoclonal antibodies (cancer), Alethia
    Click to Show/Hide
External Link
TTD: D0F6DF
 Compound Name RAP-701 Investigative [118]
Synonyms
Small stabilized receptor active peptide (ovarian cancer), RAPID Pharmaceuticals
    Click to Show/Hide
External Link
TTD: D0CO3O
 Compound Name Anti-folate receptor 1 humanized mab Investigative [118]
Synonyms
Anti-folate receptor 1 humanized mAb (cancer)
    Click to Show/Hide
External Link
TTD: D09IVP
 Compound Name Disorazol Z-LHRH conjugates Investigative [118]
Synonyms
Disorazol Z-LHRH conjugates (ovarian cancer)
    Click to Show/Hide
External Link
TTD: D08LRU
 Compound Name Anti-CGEN-153 mab Investigative [118]
Synonyms
CGEN-153; Anti-CGEN-153 mAb (ovarian cancer); CGEN-153 (Ovarian cancer), Compugen; Anti-CGEN-153 mAb (ovarian cancer), Compugen
    Click to Show/Hide
External Link
TTD: D08ENJ
 Compound Name OGX-427 + Paclitaxel Investigative [120]
External Link
CID: 91866823
TTD: D00ZBZ
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