m6A-centered Crosstalk Information
Mechanism of Crosstalk between m6A Modification and Epigenetic Regulation
| Crosstalk ID |
M6ACROT05675
|
[1] | |||
m6A modification
EN_42575
EN_42575
METTL3
Methylation
 : m6A sites
Direct
Enhancement
Non-coding RNA
EN_42575
Regulated Target
lncRNA miRNA circRNA
|
|||||
| m6A Modification: | |||||
|---|---|---|---|---|---|
| m6A Regulator | Methyltransferase-like 3 (METTL3) | WRITER | |||
| m6A Target | EN_42575 | ||||
| Epigenetic Regulation that have Cross-talk with This m6A Modification: | |||||
| Epigenetic Regulation Type | Non-coding RNA (ncRNA) | ||||
| Epigenetic Regulator | EN_42575 | LncRNA | View Details | ||
| Crosstalk Relationship | m6A → ncRNA | Enhancement | |||
| Crosstalk Mechanism | m6A regulators directly modulate the functionality of ncRNAs through specific targeting ncRNA | ||||
| Crosstalk Summary | METTL3-mediated lncRNA EN_42575 exerted a regulatory effect on IPEC-J2 cells exposed to CPB2 toxins. | ||||
| Responsed Disease | Change in bowel habit | ICD-11: ME05.1 | |||
| Cell Process | Cell proliferation | ||||
| Cell apoptosis | |||||
| Oxidative damage | |||||
In-vitro Model |
IPEC-J2
|
N.A. | Sus scrofa | CVCL_2246 | |