m6A-centered Crosstalk Information

Mechanism of Crosstalk between m6A Modification and Epigenetic Regulation
Crosstalk ID
M6ACROT05300
 [1]
Non-coding RNA DMDRMR IGF2BP3  lncRNA       miRNA   circRNA Direct Enhancement m6A modification FN1 FN1 IGF2BP3 : m6A sites
m6A Modification:
m6A Regulator Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) READER
 Regulator Info 
m6A Target Fibronectin (FN1)
 Targert Gene 
Epigenetic Regulation that have Cross-talk with This m6A Modification:
Epigenetic Regulation Type Non-coding RNA (ncRNA)
Epigenetic Regulator DMDRMR LncRNA View Details
Regulated Target Insulin like growth factor 2 mRNA binding protein 3 (IGF2BP3) View Details
Crosstalk Relationship ncRNA  →  m6A Enhancement
Crosstalk Mechanism ncRNAs directly impacts m6A modification through recruiting m6A regulator
Crosstalk Summary Mechanistically, DMDRMR bound insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3) to stabilize target genes, including the cell-cycle kinase CDK4 and three extracellular matrix components (COL6A1, LAMA5, and Fibronectin (FN1)), by specifically enhancing IGF2BP3 activity on them in an m6A-dependent manner.
Responsed Disease Renal cell carcinoma of kidney ICD-11: 2C90.0
 Disease Info 
Pathway Response Cell cycle hsa04110
Cell Process Accelerating the G1-S transition
Cell invasion and metastasis
In-vivo Model Stable DMDRMR knockdown (KD) and control cell lines were injected subcutaneously (s.c.; 1 × 107 cells/inoculum) into the flanks of recipient NOD/SCID/IL2Rbeta-null (NSG) mice. For tail vein injection, stable DMDRMR KD and control cell lines (5 × 106 cells/0.1 mL PBS) were injected into the lateral tail vein of age-matched NSG mice.
Full List of Potential Compound(s) Related to This m6A-centered Crosstalk
Fibronectin (FN1) 2 Compound(s) Regulating the Target Click to Show/Hide the Full List
 Compound Name Ocriplasmin Approved [2]
MOA Inhibitor
External Link
TTD: D0Y7XG
 Compound Name L19-TNF-alpha Phase 2 [3]
Synonyms
Fibromun
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External Link
TTD: D0GZ3A
2C90: Renal cell carcinoma 76 Compound(s) Regulating the Disease Click to Show/Hide the Full List
 Compound Name Atezolizumab Approved [4]
External Link
TTD: D0YM2K
 Compound Name Tivozanib Approved [5]
Synonyms
ASP4130/AV-951
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External Link
CID: 9911830
TTD: D0W7JZ
DrugBank: DB11800
 Compound Name Sorafenib Approved [6]
Synonyms
Nexavar; Sorafenibum; Sorafenib [INN]; Nexavar (TN); Sorafenib (INN); N-[4-Chloro-3-(trifluoromethyl)phenyl]-N'-[4-[2-(N-methylcarbamoyl)-4-pyridyloxy]phenyl]urea; N-(4-Chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcarbamoyl)-4-pyridyloxy)phenyl)urea; N-(4-chloro-3-(trifluoromethyl)phenyl)-N'-(4-(2-(N-methylcar bamoyl)-4-pyridyloxy)phenyl)urea; 4(4-{3-[4-Chloro-3-(trifluoromethyl)phenyl]ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide; 4-(4-((((4-Chloro-3-(trifluoromethyl)phenyl)amino)carbonyl)amino)phenoxy)-N-methyl-2-pyridinecarboxamide; 4-(4-(3-(4-chloro-3-trifluoromethylphenyl)ureido)phenoxy)pyridine-2-carboxyllic acid methyamide-4-methylbenzenesulfonate; 4-(4-{3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido}phenoxy)-N(sup 2)-methylpyridine-2-carboxamide; 4-[4-({[4-chloro-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenoxy]-N-methylpyridine-2-carboxamide; 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methyl-pyridine-2-carboxamide; 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide; 4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide; 4-{4-[({[4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL]AMINO}CARBONYL)AMINO]PHENOXY}-N-METHYLPYRIDINE-2-CARBOXAMIDE; Sorafenib (Pan-TK inhibitor)
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External Link
CID: 216239
TTD: D0W5HK
DrugBank: DB00398
 Compound Name Lenvatinib Approved [4]
Synonyms
E 7080; E-7080, E7080; 4-[3-chloro-4-(cyclopropylcarbamoylamino)phenoxy]-7-methoxy-quinoline-6-carboxamide
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External Link
CID: 9823820
TTD: D0R0FO
DrugBank: DB09078
 Compound Name Belzutifan Approved [7]
Synonyms
MK-6482
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External Link
CID: 117947097
TTD: D0NU8J
 Compound Name Reniale Approved [8]
Synonyms
Autologous renal tumor cell vaccine (renal cell carcinoma), LipoNova
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External Link
TTD: D0N7KV
 Compound Name Romidepsin Approved [9]
Synonyms
Chromadax; Istodax; Antibiotic FR 901228; FK 228; FK228; FR 901228; FR901228; HDInhib_000006; Chromadax (TN); FK-228; FK-901228; FR-901228; Istodax (TN); Romidepsin (USAN); Cyclo((2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl), cyclic (35)-disulfide; L-Valine, N-((3S,4E)-3-hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(2Z)-2-amino-2-butenoxyl-, (4-1)-lactone, cyclic (1-2)-disulfide; (1S,4S,7Z,10S,16E,21R)-7-Ethylidene-4,21-bis(1-methylethyl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo(8.7.6)tricos-16-ene-3,6,9,19,22-pentone; (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone; (1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-di(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetrazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone
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External Link
CID: 5352062
TTD: D0L7LC
DrugBank: DB06176
 Compound Name Avelumab Approved [4]
External Link
TTD: D0K7SX
 Compound Name Everolimus Approved [10]
Synonyms
Afinitor; Afinitor (TN); CERTICAN(R); Certican; Certican (TN); Everolimus (JAN/USAN/INN); Everolimus [USAN]; MTOR kinase inhibitors; NVP-RAD-001; RAD 001; RAD-001; RAD-001C; RAD001; RAD001, SDZ-RAD, Certican, Zortress, Afinitor, Everolimus; SDZ-RAD; Zortress
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External Link
CID: 6442177
TTD: D0K3QS
DrugBank: DB01590
 Compound Name Pazopanib HCl Approved [11]
Synonyms
Votrient (TN)
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External Link
CID: 11525740
TTD: D0F0ZY
 Compound Name Temsirolimus Approved [12]
Synonyms
Torisel
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External Link
CID: 6918289
TTD: D0ES1Q
 Compound Name Pembrolizumab Approved [4]
External Link
TTD: D08ANZ
 Compound Name CreaVax-RCC Approved [13]
Synonyms
Autologous DC vaccines (renal cell carcinoma), CreaGene; Autologous dendritic cell vaccines (renal cell carcinoma), CreaGene
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External Link
TTD: D06KPV
 Compound Name Aldesleukin Approved [14]
Synonyms
Proleukin (TN)
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External Link
TTD: D05PUD
 Compound Name Sifalimumab Approved [15]
Synonyms
Cci 779; CHEBI:79699; Torisel (TN); 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin; Temsirolimus (JAN/USAN/INN); 162635-04-3; DB06287; C15182; D06068; J-524319; (1R,2R,4S)-4-[(2R)-2-[(1R,9S,12S,15R,18R,19R,21R,23S,30S,32S,35R)-1,18-dihydroxy-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-2,3,10,14,20-pentaoxo-11,36-dioxa-4-azatricyclo[30.3.1.0; {4,9}]hexatriaconta-16,24,26,28-tetraen-12-yl]propyl]-2-methoxycyclohexyl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate
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External Link
TTD: D05NDR
 Compound Name BOL-303259-X Phase 3 [16]
Synonyms
Latanoprostene bunod; Latanoprostene bunod); NCX-116; PF-03187207; PF-3187207; BOL-303259-X1; NO donors (glaucoma), NicOx/Pfizer; NO-donating prostaglandin F2-alpha analogs (glaucoma), Pfizer; NO-donating prostaglandin F2-alpha analogs (glaucoma), NicOx/Pfizer; Nitric oxide-donating prostaglandin F2-alpha analogs (eye disease), NicOx/Pfizer; NO-donating prostaglandin F2-alpha analogs (glaucoma), NicOx/ Bausch & Lomb
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External Link
CID: 11156438
TTD: D05LQX
DrugBank: DB11660
 Compound Name Axitinib Approved [17]
Synonyms
AG 013736; AG013736; AG-013736; AG-13736; AG-013736, Axitinib; N-methyl-2-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]benzamide; N-methyl-2-((3-((1E)-2-(pyridin-2-yl)ethenyl)-1H-indazol-6-yl)sulfanyl)benzamide; Axitinib (VEGFR inhibitor)
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External Link
CID: 6450551
TTD: D01ZRI
DrugBank: DB06626
 Compound Name Nivolumab Approved [4]
External Link
TTD: D00GOV
 Compound Name HBI-8000 Phase 1/2 [4]
Synonyms
CS055; SCHEMBL5500152; GTPL8305; AKOS026750315; N-(2-amino-5-fluorophenyl)-4-{[3-(pyridin-3-yl)prop-2-enamido]methyl}benzamide
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External Link
CID: 12136798
TTD: D00SQN
DrugBank: DB06334
 Compound Name Human coagulation factor X BLA submitted [18]
External Link
TTD: D07JEW
 Compound Name Trebananib Phase 3 [19]
External Link
TTD: D9NL3R
 Compound Name Abexinostat Phase 3 [20]
Synonyms
PCI-24781; 783355-60-2; PCI 24781; CRA-024781; CRA 024781; UNII-IYO470654U; 3-((dimethylamino)methyl)-N-(2-(4-(hydroxycarbamoyl)phenoxy)ethyl)benzofuran-2-carboxamide; CRA-02478; Abexinostat(PCI-24781); PCI-24781 (Abexinostat); Abexinostat (PCI-24781); IYO470654U; 3-[(Dimethylamino)methyl]-N-[2-[4-[(hydroxyamino)carbonyl]phenoxy]ethyl]-2-benzofurancarboxamide; 3-((Dimethylamino)methyl)-N-(2-(4-(hydroxycarbamoyl)-phenoxy)ethyl)benzofuran-2-carboxamide
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External Link
CID: 11749858
TTD: D0V0SL
DrugBank: DB12565
 Compound Name Vitespen Phase 3 [21]
Synonyms
Oncophage (TN)
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External Link
TTD: D0UK2Z
 Compound Name AMD-070 Phase 3 [4]
Synonyms
AMD 070; AMD070; AMD11070; S14-0353; N-(1H-benzoimidazol-2-ylmethyl)-N-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine; N'-(1H-Benzo[d]imidazol-2-ylmethyl)-N'-(5,6,7,8-tetrahydroquinolin-8-yl)butane-1,4-diamine Trihydrobromide Dihydrate
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CID: 11256587
TTD: D0O2XQ
DrugBank: DB05501
 Compound Name Nivolumab + ipilimumab Phase 3 [22]
External Link
TTD: D0N5GV
 Compound Name Savolitinib Phase 3 [4]
Synonyms
1313725-88-0; AZD-6094; AZD6094; UNII-2A2DA6857R; CHEMBL3334567; 2A2DA6857R; Savolitinib [INN]; Volitinib(Savolitinib); Savolitinib [USAN:INN]; GTPL9918; SCHEMBL12489208; EX-A845; BDBM50023342; ZINC149738712; AKOS030526403; DB12048; compound 28 [PMID: 25148209]; HY-15959; AS-35250; 1H-1,2,3-Triazolo(4,5-b)pyrazine, 1-((1S)-1-imidazo(1,2-a)pyridin-6-ylethyl)-6-(1-methyl-1H-pyrazol-4-yl)-; KB-333895; FT-0700162; J-690125; 4-{1-[(1S)-1-{imidazo[1,2-a]pyri
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CID: 68289010
TTD: D0LW0T
DrugBank: DB12048
 Compound Name Rocapuldencel-T Phase 3 [23]
External Link
TTD: D0J0GR
 Compound Name Cotellic Phase 3 [4]
Synonyms
Cobimetinib fumarate; Cobimetinib hemifumarate; Xl-518 hemifumarate; GDC-0973 hemifumarate; UNII-6EXI96H8SV; 6EXI96H8SV; Cobimetinib fumarate [USAN]; 1369665-02-0; Cobimetinib fumarate (USAN); Cotellic (TN); CHEMBL2364607; CHEBI:90853; Methanone, (3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)phenyl)(3-hydroxy-3-(2S)-2-piperidinyl-1-azetidinyl)-, (2E)-2-butenedioate (2:1); D10615; bis[(2S)-2-{1-[3,4-difluoro-2-(2-fluoro-4-iodoanilino)benzoyl]-3-hydroxyazetidin-3-yl}piperidin-1-ium] (2E)-but-2-enedioate
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External Link
CID: 16222096
TTD: D0FJ9I
DrugBank: DB05239
 Compound Name BMS-986205 Phase 3 [4]
Synonyms
KRTIYQIPSAGSBP-KLAILNCOSA-N; 1923833-60-6; BMS986205; UNII-0A7729F42K; 0A7729F42K; GTPL9707; SCHEMBL18826792; SCHEMBL17740982; SCHEMBL19105151; EX-A2606; AKOS032954040; HY-101560; CS-0021719; Q29213697; (R)-N-(4-chlorophenyl)-2-((1s,4S)-4-(6-fluoroquinolin-4-yl)cyclohexyl)propanamide; (2R)-N-(4-chlorophenyl)-2-[4-(6-fluoroquinolin-4-yl)cyclohexyl]propanamide; (2R)-N-(4-Chlorophenyl)-2-(4-(6-fluoro-4-quinolyl)cyclohexyl)propanamide, cis; Cyclohexaneacetamide, N-(4-chlorophenyl)-4-(6-fluoro-4-quinolinyl)-alpha-methyl-, cis-(alphaR)-
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External Link
CID: 121328278
TTD: D0DP5I
DrugBank: DB14986
 Compound Name TKI258 Phase 3 [24]
Synonyms
Dovitinib; 405169-16-6; CHIR-258; TKI-258; Chir 258; 4-Amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one; CHIR258; Dovitinib (TKI-258, CHIR-258); UNII-I35H55G906; CHEMBL522892; 804551-71-1; I35H55G906; TKI 258; 1027263-12-2; (3Z)-4-Amino-5-fluoro-3-[5-(4-methyl-1-piperazinyl)-1,3-dihydro-2H-benzimidazol-2-ylidene]-2(3H)-quinolinone; C21H21FN6O; 4-Amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one
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CID: 135611162
TTD: D07OZR
 Compound Name AM0010 Phase 3 [22]
External Link
TTD: D03MYX
 Compound Name IMA-901 Phase 3 [25]
Synonyms
TUMAP vaccine (RCC), immatics; Tumor-associoated peptide vaccine (renal cell carcinoma), immatics
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External Link
TTD: D02UNP
 Compound Name NKTR 214 Phase 3 [22]
External Link
TTD: D02QQE
 Compound Name TRC105 Phase 2 [22]
External Link
TTD: D00YQI
 Compound Name CAP-232 Phase 2a [26]
Synonyms
TT-232; UNII-49D4Q4254Z; TT 232; 49D4Q4254Z; 147159-51-1; Phe-cys-tyr-trp-lys-cys-thr-NH2 (2-6)-disulfide; TLN 232; CAP 232; Phenylalanyl-cysteinyl-tyrosyl-tryptophyl-lysyl-cysteinyl-threoninamide (2-6)-disulfide; AC1OCF7X; CHEMBL539934; TLN-232; L-Threoninamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-cysteinyl-, cyclic (2-6)-disulfide; TT2-32; ZINC169289417; AKOS024458270; DB12088; NCGC00249606-01
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CID: 6918265
TTD: D09EFC
DrugBank: DB12088
 Compound Name CMN-001 Phase 2 [27]
External Link
TTD: DVQ1F5
 Compound Name DS-3201b Phase 2 [28]
Synonyms
Valemetostat; 1809336-39-7; UNII-60RD0234VE; 60RD0234VE; 1809336-39-7 (free base); DS-3201; (2R)-7-chloro-2-[trans-4-(dimethylamino)cyclohexyl]-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-2,4-dimethyl-1,3-benzodioxole-5-carboxamide; Valemetostat 2HCl; Valemetostat [INN]; Valemetostat (DS-3201); CHEMBL4597193; EZH1/2 inhibitor DS-3201; SCHEMBL18393626; SCHEMBL18393627; SCHEMBL18639210; EX-A3423; DS3201; NSC813381; s8926; NSC-813381; HY-109108; CS-0039740; D11551
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CID: 126481870
TTD: DNM79H
 Compound Name AGS-16C3F Phase 2 [4]
External Link
TTD: D0XT5Q
 Compound Name TV-Kidney-1 Phase 2 [23]
External Link
TTD: D0WZ0E
 Compound Name IMO-2055 Phase 2 [29]
External Link
TTD: D0W6HO
 Compound Name Anti-LAG3 Phase 2 [22]
External Link
TTD: D0T7OI
 Compound Name AGS-003 Phase 2 [30]
External Link
TTD: D0Q5OC
 Compound Name Ispinesib Phase 2 [31]
Synonyms
SB-715992; Ispinesib (SB-715992 /CK0238273); SB-715992, CK0238273,Ispinesib; N-(3-aminopropyl)-N-[(1R)-1-(3-benzyl-7-chloro-4-oxoquinazolin-2-yl)-2-methylpropyl]-4-methylbenzamide
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CID: 6851740
TTD: D0PW4N
DrugBank: DB06188
 Compound Name Ilixadencel Phase 2 [4]
External Link
TTD: D0PR4O
 Compound Name CRLX101 Phase 2 [4]
External Link
CID: 184196
TTD: D0ND9T
 Compound Name FolateImmune Phase 2 [32]
Synonyms
Folate-FITC; EC-17; UNII-V7YQ6134AE; V7YQ6134AE; EC17 (Folate-FITC); Folate-fluorescein conjugate; DTXSID40207031; ZMTAPBHUSYTHBY-PMERELPUSA-N; EC 17; DB12559; 910661-23-3; 1159606-35-5
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CID: 135564966
TTD: D0N8JG
DrugBank: DB12559
 Compound Name Varlilumab Phase 2 [4]
External Link
TTD: D0KV3M
 Compound Name TVI-Kidney-1 Phase 2 [33]
External Link
TTD: D0JH5K
 Compound Name OSI-027 Phase 2 [34]
External Link
CID: 135398516
TTD: D0H7XL
DrugBank: DB12387
 Compound Name XL880 Phase 2 [35]
Synonyms
GSK 089; GSK 1363089; GSK1363089; XL 880; GSK1363089, GSK089, foretinib, EXEL-2880, XL880; 88Z; MET inhibitors
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CID: 42642645
TTD: D0D1GF
DrugBank: DB12307
 Compound Name Girentuximab I-124 Phase 2 [36]
Synonyms
Redectane (TN)
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External Link
TTD: D0BH7Z
 Compound Name Autologous renal cell carcinoma vaccine Phase 2 [37]
External Link
TTD: D08FKD
 Compound Name RX-0201 Phase 2 [4]
External Link
TTD: D07SYZ
 Compound Name Human interleukin-2 Phase 2 [38]
Synonyms
Pulmoleukin; Human interleukin-2 (inhaled, renal cell carcinoma); Human IL-2 (inhaled, renal cell carcinoma),Immunservice; Human interleukin-2 (inhaled, renal cell carcinoma), Immunservice
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External Link
TTD: D04OJM
 Compound Name CB-839 Phase 2 [4]
External Link
CID: 71577426
TTD: D01PBW
DrugBank: DB15232
 Compound Name ATN-161 Phase 2 [39]
Synonyms
PHSCN; PHSCN, University of Michigan; Angiogenesis inhibitors (cancer), Attenuon; Integrin antagonists (cancer), Attenuon; Ac-PHSCN-NH2, University of Michigan
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External Link
CID: 9960285
TTD: D00QVT
 Compound Name TV1-Kidney-1 Phase 2 [40]
External Link
TTD: D00HMZ
 Compound Name CCT301-38 (targeting ROR2) Phase 1/2 [41]
External Link
TTD: D0RA9C
 Compound Name LAG525 Phase 1/2 [4]
External Link
TTD: D0E4LS
 Compound Name CCT301-59 (targeting ROR2) Phase 1/2 [41]
External Link
TTD: D0C2PH
 Compound Name Anti-C-met CAR-T cells Phase 1/2 [42]
External Link
TTD: D0A3OE
 Compound Name CDX-014 Phase 1/2 [4]
External Link
TTD: D09WXY
 Compound Name IL-2 XL Phase 1/2 [43]
Synonyms
IL-2 XL (controlled release, Medusa); IL-2 XL (controlled release, Medusa), Flamel; Interleukin-2 (long-acting, Medusa), Flamel
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TTD: D08XFA
 Compound Name ARO-HIF2 Phase 1 [44]
External Link
TTD: DE8V1R
 Compound Name AGS-16 mab Phase 1 [45]
Synonyms
AGS-16M18
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External Link
TTD: D0X7MY
 Compound Name Neovastat Phase 1 [46]
External Link
TTD: D0T4BL
 Compound Name Biomed 101 Discontinued in Phase 1 [47]
Synonyms
SC-41930; SC 41930; 120072-59-5; CHEMBL14823; CGS 24115; 7-(3-(4-Acetyl-3-methoxy-2-propylphenoxy)propoxy)-3,4-dihydro-8-propyl-2H-1-benzopyran-2-carboxylic acid; 2H-1-Benzopyran-2-carboxylic acid, 7-(3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy)-3,4-dihydro-8-propyl-; 2H-1-Benzopyran-2-carboxylicacid, 7-[3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy]-3,4-dihydro-8-propyl-; 7-(3-(4-acetyl-3-methoxy-2-propylphenoxy)propoxy)-8-propylchroman-2-carboxylic acid; SC-41390
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CID: 114999
TTD: D0S0WN
 Compound Name AMG 172 Phase 1 [48]
External Link
TTD: D0NC1Q
 Compound Name Anti-hCD70 CAR transduced PBL Phase 1 [49]
External Link
TTD: D0JO9M
 Compound Name Veglin Phase 1 [50]
External Link
TTD: D0G6GB
 Compound Name IL-7/CD80-expressing allogeneic RCC-26 tumor cell vaccine Phase 1 [51]
Synonyms
RCC-26 tumor cell vaccine; IL-7/CD80-expressing allogeneic RCC-26 tumorcell vaccine (renal cell carcinoma)
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TTD: D04HWK
 Compound Name Vorsetuzumab mafodotin Discontinued in Phase 1 [52]
External Link
TTD: D08WTE
 Compound Name BCL-004 Investigative [53]
External Link
TTD: D09KTE
 Compound Name GM-CAIX Investigative [53]
Synonyms
GM-CSF/cancer antigen chimeric protein (renal cancer), Kite
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TTD: D07OQJ
 Compound Name GS-168 Investigative [53]
Synonyms
GS-168A
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TTD: D05YWN
 Compound Name STF-62247 Investigative [53]
Synonyms
Renal cell carcinoma therapy, Stanford University
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CID: 704473
TTD: D01CIN
References
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